Successful multi-site measurement of antisaccade performance deficits in schizophrenia

Schizophrenia Research

Volumn 89, Issue 1-3, 2007, Pages 320-329

  Radant, Allen D ^a,b   Dobie, Dorcas J ^a,b   Calkins, Monica E ^c   Olincy, Ann ^d   Braff, David L ^e   Cadenhead, Kristin S ^e   Freedman, Robert ^d   Green, Michael F ^f   Greenwood, Tiffany A ^e   Gur, Raquel E ^c   Light, Gregory A ^e   Meichle, Sean P ^a,b   Mintz, Jim ^f   Nuechterlein, Keith H ^f   Schork, Nicholas J ^e   Seidman, Larry J ^g   Siever, Larry J ^h   Silverman, Jeremy M ^h   Stone, William S ^g   Swerdlow, Neal R ^e   Tsuang, Ming T ^e,i,j   Turetsky, Bruce I ^c   Tsuang, Debby W ^a,b   more..

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Education   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^h MOUNT SINAI SCHOOL OF MEDICINE   (United States)

ⁱ MASSACHUSETTS MENTAL HEALTH CENTER   (United States)

^j HARVARD UNIVERSITY   (United States)

more..

Author keywords

Antisaccade; Endophenotype; Oculomotor; Schizophrenia; Validity

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; HUMAN; INFORMATION PROCESSING; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUALITY CONTROL; REGRESSION ANALYSIS; SCHIZOPHRENIA; SCORING SYSTEM; TASK PERFORMANCE;

ADOLESCENT; ADULT; AGED; ATTENTION; COLOR PERCEPTION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OBSERVER VARIATION; ORIENTATION; PHENOTYPE; REACTION TIME; REFERENCE VALUES; SACCADES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; UNITED STATES;

EID: 33845311169     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2006.08.010     Document Type: Article

References (50)

1. Andreasen N.C. The Scale for the Assessment of Negative Symptoms (SANS) (1983), The University of Iowa, Iowa CIty, Iowa
2. Andreasen N.C. The Scale for the Assessment of Positive Symptoms (1984), The University of Iowa, Iowa City, Iowa
3. Berrettini W.H. Genetic bases for endophenotypes in psychiatric disorders. Dialogues Clin. Neurosci. 7 2 (2005) 95-101
4. Braff D.L., and Freedman R. Endophenotypes in Studies of the Genetics of Schizophrenia. In: Davis K.L., Charney D., Coyle J.T., and Nemeroff C.B. (Eds). Neuropsychopharmacology: the Fifth Generation of Progress: an Official Publication of the American College of Neuropsychopharmacology (2002), Lippincott/Williams and Wilkins, Philadelphia 703-716
5. Braff D.L., and Light G.A. The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia. Dialogues Clin. Neurosci. 7 2 (2005) 125-135
6. Broerse A., Crawford T.J., and den Boer J.A. Parsing cognition in schizophrenia using saccadic eye movements: a selective overview. Neuropsychologia 39 7 (2001) 742-756
7. Bunney W.E., and Bunney B.G. Evidence for a compromised dorsolateral prefrontal cortical parallel circuit in schizophrenia. Brain Res. Brain Res. Rev. 31 2-3 (2000) 138-146
8. Calkins M.E., Iacono W.G., and Curtis C.E. Smooth pursuit and antisaccade performance evidence trait stability in schizophrenia patients and their relatives. Int. J. Psychophysiol. 49 2 (2003) 139-146
9. Calkins M.E., Curtis C.E., Iacono W.G., and Grove W.M. Antisaccade performance is impaired in medically and psychiatrically healthy biological relatives of schizophrenia patients. Schizophr. Res. 71 1 (2004) 167-178
10. Calkins, M.E., Dobie, D.J., Cadenhead, K.S., Olincy, A., Freedman, R., Green, M.F., Greenwood, T.A., Gur, R.E., Gur, R.C., Light, G.A., Mintz, J., Nuechterlein, K.H., Radant, A.D., Schork, N.J., Seidman, L.J., Siever, L.J., Silverman, J.M., Stone, W.S., Swerdlow, N.R., Tsuang, D.W., Tsuang, M.T., Turetsky, B.I., Braff, D.L., in press. The Consortium on the Genetics of Endophenotypes in Schizophrenia (COGS): "Model" Recruitment, Assessment, and Endophenotyping Methods for a Multi-Site Collaboration. Schizophr Bull.
11. Crawford T.J., Haeger B., Kennard C., Reveley M.A., and Henderson L. Saccadic abnormalities in psychotic patients. I. Neuroleptic-free psychotic patients. Psychol. Med. 25 3 (1995) 461-471
12. Curtis C.E., Calkins M.E., Grove W.M., Feil K.J., and Iacono W.G. Saccadic disinhibition in patients with acute and remitted schizophrenia and their first-degree biological relatives. Am. J. Psychiatry 158 1 (2001) 100-106
13. Ettinger U., Kumari V., Crawford T.J., Davis R.E., Sharma T., and Corr P.J. Reliability of smooth pursuit, fixation, and saccadic eye movements. Psychophysiology 40 4 (2003) 620-628
14. Ettinger U., Kumari V., Chitnis X.A., Corr P.J., Crawford T.J., Fannon D.G., O'Ceallaigh S., Sumich A.L., Doku V.C., and Sharma T. Volumetric neural correlates of antisaccade eye movements in first-episode psychosis. Am. J. Psychiatry 161 10 (2004) 1918-1921
15. Ettinger U., Picchioni M., Hall M.H., Schulze K., Toulopoulou T., Landau S., Crawford T.J., and Murray R.M. Antisaccade performance in monozygotic twins discordant for schizophrenia: the Maudsley twin study. Am. J. Psychiatry 163 3 (2006) 543-545
16. Fukushima J., Fukushima K., Chiba T., Tanaka S., Yamashita I., and Kato M. Disturbances of voluntary control of saccadic eye movements in schizophrenic patients. Biol. Psychiatry 23 7 (1988) 670-677
17. Gooding D.C., and Tallent K.A. The association between antisaccade task and working memory task performance in schizophrenia and bipolar disorder. J. Nerv. Ment. Dis. 189 1 (2001) 8-16
18. Gooding D.C., Mohapatra L., and Shea H.B. Temporal stability of saccadic task performance in schizophrenia and bipolar patients. Psychol. Med. 34 5 (2004) 921-932
19. Gooding D.C., Shea H.B., and Matts C.W. Saccadic performance in questionnaire-identified schizotypes over time. Psychiatry Res. 133 2-3 (2005) 173-186
20. Gottesman I.I. Schizophrenia epigenesis: past, present, and future. Acta Psychiatr. Scand., Suppl. 384 (1994) 26-33
21. Gottesman I.I., and Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160 4 (2003) 636-645
22. Harrison P.J., and Weinberger D.R. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol. Psychiatry 10 1 (2005) 40-68 (image 45)
23. Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrika 75 4 (1988) 800-802
24. Hoover D.R., and Blackwelder W.C. Allocation of subjects to test null relative risks smaller than one. Stat. Med. 20 20 (2001) 3071-3082
25. Hutton S.B., and Ettinger U. The antisaccade task as a research tool in psychopathology: a critical review. Psychophysiology 43 3 (2006) 302-313
26. Jastak S., and Wilkinson G. Wide Range Achievement Test-Revised 3 (1993), Jastak Associates, Wilmington, DE
27. Katsanis J., Kortenkamp S., Iacono W.G., and Grove W.M. Antisaccade performance in patients with schizophrenia and affective disorder. J. Abnorm. Psychology 106 3 (1997) 468-472
28. Kumari V., Ettinger U., Crawford T.J., Zachariah E., and Sharma T. Lack of association between prepulse inhibition and antisaccadic deficits in chronic schizophrenia: implications for identification of schizophrenia endophenotypes. J. Psychiatr. Res. 39 3 (2005) 227-240
29. Levy D.L., O'Driscoll G., Matthysse S., Cook S.R., Holzman P.S., and Mendell N.R. Antisaccade performance in biological relatives of schizophrenia patients: a meta-analysis. Schizophr. Res. 71 1 (2004) 113-125
30. Louchart-de la Chapelle S., Nkam I., Houy E., Belmont A., Menard J.F., Roussignol A.C., Siwek O., Mezerai M., Guillermou M., Fouldrin G., Levillain D., Dollfus S., Campion D., and Thibaut F. A concordance study of three electrophysiological measures in schizophrenia. Am. J. Psychiatry 162 3 (2005) 466-474
31. Malone S.M., and Iacono W.G. Error rate on the antisaccade task: heritability and developmental change in performance among preadolescent and late-adolescent female twin youth. Psychophysiology 39 5 (2002) 664-673
32. Maruff P., Purcell R., Tyler P., Pantelis C., and Currie J. Abnormalities of internally generated saccades in obsessive-compulsive disorder. Psychol. Med. 29 6 (1999) 1377-1385
33. Matsuda T., Matsuura M., Ohkubo T., Ohkubo H., Matsushima E., Inoue K., Taira M., and Kojima T. Functional MRI mapping of brain activation during visually guided saccades and antisaccades: cortical and subcortical networks. Psychiatry Res. 131 2 (2004) 147-155
34. McDowell J.E., and Clementz B.A. The effect of fixation condition manipulations on antisaccade performance in schizophrenia: studies of diagnostic specificity. Exp. Brain Res. 115 2 (1997) 333-344
35. McDowell J.E., Myles-Worsley M., Coon H., Byerley W., and Clementz B.A. Measuring liability for schizophrenia using optimized antisaccade stimulus parameters. Psychophysiology 36 1 (1999) 138-141
36. McDowell J.E., Brenner C.A., Myles-Worsley M., Coon H., Byerley W., and Clementz B.A. Ocular motor delayed-response task performance among patients with schizophrenia and their biological relatives. Psychophysiology 38 1 (2001) 153-156
37. Mowry B.J., and Nancarrow D.J. Molecular genetics of schizophrenia. Clin. Exp. Pharmacol. Physiol. 28 1-2 (2001) 66-69
38. Myles-Worsley M., Coon H., McDowell J., Brenner C., Hoff M., Lind B., Bennett P., Freedman R., Clementz B., and Byerley W. Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families. Am. J. Med. Genet. 88 5 (1999) 544-550
39. NIMH. NIMH Genetics Initiative: Family Interview for Genetic Studies (FIGS) (1992), National Institute of Mental Health, Rockville, MD
40. Nurnberger Jr. J.I., Blehar M.C., Kaufmann C.A., York-Cooler C., Simpson S.G., Harkavy-Friedman J., Severe J.B., Malaspina D., and Reich T. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch. Gen. Psychiatry 51 11 (1994) 849-859 (discussion 863-844)
41. O'Driscoll G.A., Depatie L., Holahan A.L., Savion-Lemieux T., Barr R.G., Jolicoeur C., and Douglas V.I. Executive functions and methylphenidate response in subtypes of attention-deficit/hyperactivity disorder. Biol. Psychiatry 57 11 (2005) 1452-1460
42. Olincy A., Ross R.G., Youngd D.A., and Freedman R. Age diminishes performance on an antisaccade eye movement task. Neurobiol. Aging 18 5 (1997) 483-489
43. Polli F.E., Barton J.J., Vangel M., Goff D.C., Iguchi L., and Manoach D.S. Schizophrenia patients show intact immediate error-related performance adjustments on an antisaccade task. Schizophr. Res. 82 2-3 (2006) 191-201
44. Radant A.D., and Hommer D.W. A quantitative analysis of saccades and smooth pursuit during visual pursuit tracking. A comparison of schizophrenics with normals and substance abusing controls. Schizophr. Res. 6 3 (1992) 225-235
45. Rosenberg D.R., Averbach D.H., O'Hearn K.M., Seymour A.B., Birmaher B., and Sweeney J.A. Oculomotor response inhibition abnormalities in pediatric obsessive-compulsive disorder. Arch. Gen. Psychiatry 54 9 (1997) 831-838
46. Ross D.E., Buchanan R.W., Lahti A.C., Medoff D., Bartko J.J., Compton A.D., and Thaker G.K. The relationship between smooth pursuit eye movements and tardive dyskinesia in schizophrenia. Schizophr. Res. 31 2-3 (1998) 141-150
47. Sidák Z. Rectangular confidence regions for the means of multivariate normal distributions. J. Am. Stat. Assoc. 62 (1967) 626-633
48. StataCorp. Stata Statistical Software: Release 9 (2005), StataCorp LP, College Station, TX
49. Tsuang M.T., Stone W.S., and Faraone S.V. Genes, environment and schizophrenia. Br. J. Psychiatr., Suppl. 40 (2001) s18-s24
50. Waterwort D.M., Bassett A.S., and Brzustowicz L.M. Recent advances in the genetics of schizophrenia. Cell. Mol. Life Sci. 59 2 (2002) 331-348