Longitudinal studies of antisaccades in antipsychotic-naive first-episode schizophrenia

Psychological Medicine

Volumn 36, Issue 4, 2006, Pages 485-494

  Harris, Margret S H ^a   Reilly, James L ^a   Keshavan, Matcheri S ^b   Sweeney, John A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZATROPINE; HALOPERIDOL; OLANZAPINE; RISPERIDONE;

ADULT; ARTICLE; ATTENTION; BRAIN DYSFUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EXPOSURE; EXTRAPYRAMIDAL SYMPTOM; FEMALE; FOLLOW UP; HUMAN; LATENT PERIOD; LONGITUDINAL STUDY; MALE; PREFRONTAL CORTEX; RESPONSE TIME; SACCADIC EYE MOVEMENT; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; TASK PERFORMANCE;

ADOLESCENT; ADULT; ANTIPSYCHOTIC AGENTS; FEMALE; HALOPERIDOL; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; RISPERIDONE; SACCADES; SCHIZOPHRENIA; TIME FACTORS;

EID: 33644924944     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291705006756     Document Type: Article

References (50)

1. Andreasen, N. C. (1984a). Scale for the Assessment of Negative Symptoms. University of Iowa Press: Iowa City, IA.
2. Andreasen, N. C. (1984b). Scale for the Assessment of Positive Symptoms. University of Iowa Press: Iowa City, IA.
3. Barch, D. M., Carter, C. S., Braver, T. S., Sabb, F. W., MacDonald, A., Noll, D. C. & Cohen, J. D. (2001). Selective deficits in prefrontal cortex function in medication-naive patients with schizophrenia. Archive of General Psychiatry 58, 280-288.
4. Barch, D. M., Carter, C. S., Hachten, P. C., Usher, M. & Cohen, J. D. (1999). The 'benefits' of distractibility: Mechanisms underlying increased Stroup effects in schizophrenia. Schizophrenia Bulletin 25, 749-762.
5. Bilder, R. M., Goldman, R. S., Robinson, D., Reiter, G., Bell, L., Bates, J. A., Pappadopulos, E., Willson, D. F., Alvir, J. M., Woerner, M. G., Geisler, S., Kane, J. M. & Lieberman, J. A. (2000). Neuropsychology of first-episode schizophrenia: Initial characterization and clinical correlates. American Journal of Psychiatry 157, 549-559.
6. Brownstein, J., Krastoshevsky, O., McCollum, C., Kundamal, S., Matthysse, S., Holzman, P. S., Mendell, N. R. & Levy, D. L. (2003). Antisaccade performance is abnormal in schizophrenia patients but not in their biological relatives. Schizophrenia Research 63, 13-25.
7. Bruce, C. J. & Goldberg, M. E. (1985). Primate frontal eye fields. I. Single neurons discharging before saccades. Journal of Neurophysiology 53, 603-635.
8. Burke, J. G. & Reveley, M. A. (2002). Improved antisaccade performance with risperidone in schizophrenia. Journal of Neurology, Neurosurgery & Psychiatry 72, 449-454.
9. Clementz, B. A. (1996). The ability to produce express saccades as a function of gap interval among schizophrenia patients. Experimental Brain Research 111, 121-130.
10. Clementz, B. A., McDowell, J. E. & Zisook, S. (1994). Saccadic system functioning among schizophrenia patients and their first-degree biological relatives. Journal of Abnormal Psychology 103, 277-287.
11. Corbetta, M., Miezin, F. M., Shulman, G. L. & Petersen, S. E. (1993). A PET study of visuospatial attention. Journal of Neuroscience 13, 1202-1226.
12. Crawford, T. J., Haeger, B., Kennard, C., Reveley, M. A. & Henderson, L. (1995). Saccadic abnormalities in psychotic patients. II. The role of neuroleptic treatment. Psychological Medicine 25, 473-483.
13. Curtis, C. E., Calkins, M. E., Grove, W. M., Feil, K. J. & Iacono, W. G. (2001). Saccadic disinhibition in patients with acute and remitted schizophrenia and their first-degree biological relatives. American Journal of Psychiatry 158, 100-106.
14. Everling, S. & Fischer, B. (1998). The antisaccade: A review of basic research and clinical studies. Neuropsychologia 36, 885-899.
15. Everling, S. & Munoz, D. P. (2000). Neuronal correlates for preparatory set associated with pro-saccades and anti-saccades in the primate frontal eye field. Journal of Neuroscience 20, 387-400.
16. Fukushima, J., Morita, N., Fukushima, A. K., Chiba, T., Tanaka, S. & Yamashita, I. (1990). Voluntary control of saccadic eye movements in patients with schizophrenic and affective disorders. Journal of Psychiatry Research 24, 9-24.
17. Funahashi, S., Chafee, M. V. & Goldman-Rakic, P. S. (1993). Prefrontal neuronal activity in rhesus monkeys performing a delayed anti-saccade task. Nature 365, 753-758.
18. Goldberg, T. E., Hyde, M., Kleinman, J. E. & Weinberger, D. R. (1993). Course of schizophrenia: Neuropsychological evidence for a static encephalopathy. Schizophrenia Bulletin 19, 797-804.
19. Goldman-Rakic, P. S. (1988). Topography of cognition: Parallel distributed networks in primate association cortex. Annual Review of Neuroscience 11, 137-156.
20. Gooding, D. C., Mohapatra, L. & Shea, H. B. (2004). Temporal stability of saccadic task performance in schizophrenia and bipolar patients. Psychological Medicine 34, 921-932.
21. Guitton, D., Buchtel, H. A. & Douglas, R. M. (1985). Frontal lobe lesions in man cause difficulties in suppressing reflexive glances and in generating goal-directed saccades. Experimental Brain Research 58, 455-472.
22. Gur, R. E., Cowell, P. E., Latshaw, A., Turetsky, B. I., Grossman, R. I., Arnold, S. E., Bilker, W. B. & Gur, R. C. (2000). Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia. Archives of General Psychiatry 57, 761-768.
23. Hallett, P. E. (1978). Primary and secondary saccades to goals defined by instructions. Vision Research 18, 1279-1296.
24. Hazlett, E. A., Buchsbaum, M. S., Jeu, L. A., Nenadic, I., Fleischman, M. B., Shihabuddin, L., Haznedar, M. M. & Harvey, P. D. (2000). Hypofrontality in unmedicated schizophrenia patients studied with PET during performance of a serial verbal learning task. Schizophrenia Research 43, 33-46.
25. Hedeker, D. & Gibbons, R. D. (1997). Application of random-effects pattern-mixture models for missing data in longitudinal studies. Psychological Methods 2, 64-78.
26. Heide, W., Binkofski, F., Seitz, R. J., Posse, S., Nitschke, M. F., Freund, H. J. & Koempf, D. (2001). Activation of frontoparietal cortices during memorized triple-step sequences of saccadic eye movements: An fMRI study. European Journal of Neuroscience 13, 1177-1189.
27. Hill, S. K., Schuepbach, D., Herbener, E. S., Keshavan, M. S. & Sweeney, J. A. (2004). Pretreatment and longitudinal studies of neuropsychological deficits in antipsychotic-naive patients with schizophrenia. Schizophrenia Research 68, 49-63.
28. Ho, B. C., Andreasen, N. C., Nopoulos, P., Arndt, S., Magnotta, V. & Flaum, M. (2003). Progressive structural brain abnormalities and their relationship to clinical outcome: A longitudinal magnetic resonance imaging study early in schizophrenia. Archives of General Psychiatry 60, 585-594.
29. Hollingshead, A. B. (1975). Four Factor Index of Social Status. Yale University, Department of Sociology: New Haven, CT.
30. Hutton, S. B., Crawford, T. J., Puri, B. K., Duncan, L. J., Chapman, M., Kennard, C., Barnes, T. R. E. & Joyce, E. M. (1998). Smooth pursuit and saccadic abnormalities in first-episode schizophrenia. Psychological Medicine 28, 685-692.
31. Hutton, S. B., Joyce, E. M., Barnes, T. R. E. & Kennard, C. (2002). Saccadic distractibility in first-episode schizophrenia. Neuropsychologia 40, 1729-1736.
32. Keefe, R. S. E., Silva, S. G., Perkins, D. O. & Lieberman, J. A. (1999). The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: A review and meta-analysis. Schizophrenia Bulletin 25, 201-222.
33. McDowell, J. E., Brown, G. G., Paulus, M., Martinez, A., Stewart, S. E., Dubowitz, D. J. & Braff, D. L. (2002). Neural correlates of refixation saccades and antisaccades in normal and schizophrenia subjects. Biological Psychiatry 51, 216-223.
34. McEvoy, J. P., Hogarty, G. E. & Steingard, S. (1991). Optimal dose of neuroleptic in acute schizophrenia: A controlled study of the neuroleptic threshold and higher haloperidol dose. Archives of General Psychiatry 48, 739-745.
35. Muller, N., Riedel, M., Eggert, T. & Straube, A. (1999). Internally and externally guided voluntary saccades in unmedicated and medicated schizophrenic patients: Part II. Saccadic latency, gain, and fixation suppression errors. European Archives of Psychiatry and Clinical Neuroscience 249, 7-14.
36. Munoz, D. P. & Everling, S. (2004). Look away: The anti-saccade task and the voluntary control of eye movement. Nature Reviews Neuroscience 5, 218-228.
37. O'Driscoll, G. A., Alpert, N. M., Matthysse, S. W., Levy, D. L., Rauch, S. L. & Holzman, P. S. (1995). Functional neuroanatomy of antisaccade eye movements investigated with positron emission tomography. Proceedings of the National Academy of Sciences USA 92, 925-929.
38. Overall, J. E. & Gorham, D. R. (1962). The Brief Psychiatric Rating Scale. Psychological Report 10, 799-812.
39. Perry, R. J. & Zeki, S. (2000). The neurology of saccades and covert shifts in spatial attention: An event-related fMRI study. Brain 123, 2273-2288.
40. Pierrot-Deseilligny, C. (1994). Saccade and smooth-pursuit impairment after cerebral hemispheric lesions. European Neurology 34, 121-134.
41. Pierrot-Deseilligny, C., Muri, R. M., Ploner, C. J., Gaymard, B., Demeret, S. & Rivaud-Pechoux, S. (2003). Decisional role of the dorsolateral prefrontal cortex in ocular motor behaviour. Brain 126, 1460-1473.
42. Posner, M. I., Early, T. S., Reiman, E., Pardo, P. J. & Dhawan, M. (1988). Asymmetries in hemispheric control of attention in schizophrenia. Archives of General Psychiatry 45, 814-821.
43. Raemaekers, M., Jansma, J. M., Cahn, W., van der Geest, J. N., van der Linden, J. A., Kahn, R. S. & Ramsey, N. F. (2002). Neuronal substrate of the saccadic inhibition deficit in schizophrenia investigated with 3-dimensional event-related functional magnetic resonance imaging. Archives of General Psychiatry 59, 313-320.
44. Reilly, J. L., Harris, M. S., Keshavan, M. S. & Sweeney, J. A. (2005). Abnormalities in visually guided saccades suggest corticofugal dysregulation in never-treated schizophrenia. Biological Psychiatry 57, 145-154.
45. Sereno, A. B. & Holman, P. S. (1995). Antisaccades and smooth pursuit eye movements in schizophrenia. Biological Psychiatry 37, 394-401.
46. Spitzer, R. L., Williams, J. B. W., Gibbons, M. & First, M. (1987). Structured Clinical Interview for DSM-III-R (SCID). New York State Psychiatric Institute: New York.
47. Sweeney, J. A., Levy, D. & Harris, M. S. (2002). Commentary: Eye movement research with clinical populations. In Brain's Eye: Neurobiological and Clinical Aspects of Oculomotor Research (ed. J. Hyönä, D. P. Munoz, W. Heide and R. Radach), pp. 507-522. Elsevier Science B.V. Amsterdam, The Netherlands.
48. Sweeney, J. A., Mintun, M. A., Kwee, S., Wiseman, M. B., Brown, D. L., Rosenberg, D. R. & Carl, J. R. (1996). Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. Journal of Neurophysiology 75, 454-468.
49. Tamminga, C. A. (2003). Similarities and differences among antipsychotics. Journal of Clinical Psychiatry 64 (Suppl. 17), 7-10.
50. Walker, R., Husain, M., Hodgson, T. L., Harrison, J. & Kennard, C. (1998). Saccadic eye movement and working memory deficits following damage to human prefrontal cortex. Neuropsychologia 36, 1141-1159.