Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: Computational morphometry study

British Journal of Psychiatry

Volumn 186, Issue MAY, 2005, Pages 369-377

  McDonald, Colm ^a   Bullmore, Ed ^b   Sham, Pak ^a   Chitnis, Xavier ^a   Suckling, John ^b   MacCabe, James ^a   Walshe, Muriel ^a   Murray, Robin M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BIPOLAR DISORDER; BRAIN SCINTISCANNING; BRAIN SIZE; CEREBELLUM; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; INSULA; MAJOR CLINICAL STUDY; MALE; MORPHOMETRICS; NEOCORTEX; SCHIZOPHRENIA; TEMPORAL LOBE; THALAMUS; VOLUMETRY; WHITE MATTER;

ADULT; AGED; BIPOLAR DISORDER; BRAIN; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; SCHIZOPHRENIA;

EID: 18644367817     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.186.5.369     Document Type: Article

References (43)

1. Altshuler, L. L., Bartzokis, G., Grieder, T., et al (2000) An MRI study of temporal lobe structures in men with bipolar disorder or schizophrenia. Biological Psychiatry, 48, 147-162.
2. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM-IV). Washington, DC: American Psychiatric Association.
3. Andreasen, N. C., Paradiso, S. & O'Leary, D. S. (1998) 'Cognitive dysmetria'as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical-cerebellar circuitry? Schizophrenia Bulletin, 24, 203-218.
4. Ashburner, J. & Friston, K. J. (2000) Voxel-based morphometry - the methods. Neuroimage, 11, 805-821.
5. Bearden, C. E., Hoffman, K. M. & Cannon, T. D. (2001) The neuropsychology and neuroanatomy of bipolar disorder: a critical review. Bipolar Disorders, 3, 106-150.
6. Bullmore, E. T., Frangou, S. & Murray, R. M. (1997) The dysplastic net hypothesis: an integration of developmental and dysconnectivity theories of schizophrenia. Schizophrenia Research, 28, 143-156.
7. Bullmore, E. T., Suckling, J., Overmeyer, S., et al (1999) Global, voxel, and cluster tests, by theory and permutation, for a difference between two groups of structural MR images of the brain. IEEE Transactions on Medical Imaging, 18, 32-42.
8. Davis, K. L., Stewart, D. G., Friedman, J. I., et al (2003) White matter changes in schizophrenia: evidence for myelin-related dysfunction. Archives of General Psychiatry, 60, 443-456.
9. Drevets, W. C., Price, J. L., Simpson, J. R., Jr, et al (1997) Subgenual prefrontal cortex abnormalities in mood disorders. Nature, 386, 824-827.
10. Friedman, L., Findling, R. L., Kenny, J. T., et al (1999) An MRI study of adolescent patients with either schizophrenia or bipolar disorder as compared to healthy control subjects. Biological Psychiatry, 46, 78-88.
11. Frodl, T., Meisenzahl, E. M., Zetzsche, T., et al (2002) Hippocampal changes in patients with a first episode of major depression. American Journal of Psychiatry, 159, 1112-1118.
12. Good, C. D., Johnsrude, I. S., Ashburner, J., et al (2001) A voxel-based morphometric study of ageing in 465 normal adult human brains. NeuroImage, 14, 21-36.
13. Hakak, Y., Walker, J. R., Li, C., et al (2001) Genomewide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proceedings of the National Academy of Sciences of the United States of America, 98, 4746-4751.
14. Harvey, I., Persaud, R., Ron, M. A., et al (1994) Volumetric MRI measurements in bipolars compared with schizophrenics and healthy controls. Psychological Medicine, 24, 689-699.
15. Hayasaka, S. & Nichols, T. E. (2003) Validating cluster size inference: random field and permutation methods. NeuroImage, 20, 2343-2356.
16. Hirayasu, Y., Tanaka, S., Shenton, M. E., et al (2001) Prefrontal gray matter volume reduction in first episode schizophrenia. Cerebral Cortex, 11, 374-381.
17. Hulshoff Pol, H. E., Schnack, H. G., Mandl, R. C., et al (2001) Focal gray matter density changes in schizophrenia. Archives of General Psychiatry, 58, 1118-1125.
18. Kasai, K., Shenton, M. E., Salisbury, D. F., et al (2003) Differences and similarities in insular and temporal pole MRI gray matter volume abnormalities in first-episode schizophrenia and affective psychosis. Archives of General Psychiatry, 60, 1069-1077.
19. Kieseppa, T., van Erp, T. G., Haukka, J., et al (2003) Reduced left hemispheric white matter volume in twins with bipolar I disorder, Biological Psychiatry, 54, 896-905.
20. Kraepelin, E. (1899) Psychiatrie, ein Lehrbuch für Studierende und Ärtze (6th edn). Leipzig: Barth.
21. Kubicki, M., Shenton, M. E., Salisbury, D. F., et al (2002) Voxel-based morphometric analysis of gray matter in first episode schizophrenia. Neuroimage, 17, 1711-1719.
22. Lang, D. J., Kopala, L. C.,Vandorpe, R. A., et al (2001) An MRI study of basal ganglia volumes in first-episode schizophrenia patients treated with risperidone. American Journal of Psychiatry, 158, 625-631.
23. Lim, K. O., Rosenbloom, M. J., Faustman, W. O., et al (1999) Cortical gray matter deficit in patients with bipolar disorder. Schizophrenia Research, 40, 219-227.
24. Lopez-Larson, M. P., DelBello, M. P., Zimmerman, M. E., et al (2002) Regional prefrontal gray and white matter abnormalities in bipolar disorder. Biological Psychiatry, 52, 93-100.
25. McDonald, C., Bullmore, E. T., Sham, P. C., et al (2004) Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Archives of General Psychiatry, 61, 974-984.
26. Moore, G. J., Bebchuk, J. M., Wilds, I. B., et al (2000) Lithium-induced increase in human brain grey matter. Lancet, 356, 1241-1242.
27. Nopoulos, P. C., Ceilley, J. W., Gailis, E. A., et al (1999) An MRI study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dysmetria concept. Biological Psychiatry, 46, 703-711.
28. Office of Population Censuses and Surveys (1991) Standard Occupational Classification. Volume 3: Social Classification and Coding Methodolgy. London: HMSO.
29. Pearfson, G. D., Barta, P. E., Powers, R. E., et al (1997) Ziskind-Somerfeld Research Award 1996. Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder. Biological Psychiatry, 41, 1-14.
30. Sigmundsson, T., Suckling, J., Maier, M., et al (2001) Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms. American Journal of Psychiatry, 158, 234-243.
31. Spalletta, G., Tomaiuolo, F., Marino, V., et al (2003) Chronic schizophrenia as a brain misconnection syndrome: a white matter voxel-based morphometry study. Schizophrenia Research, 64, 15-23.
32. Spitzer, R. L. & Endicott, J. (1978) Schedule for Affective Disorders and Schizophrenia - Lifetime Version. New York: New York State Psychiatric Institute.
33. Talairach, J. & Tournoux, P. (1988) Co-Planar Stereotoxic Atlas of the Human Brain. New York: Thieme.
34. Tkachev, D., Mimmack, M. L., Ryan, M. M., et al (2003) Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet, 362, 798-805.
35. Uranova, N., Orlovskaya, D., Vikhreva, O., et al (2001) Electron microscopy of oligodendroglia in severe mental illness. Brain Research Bulletin, 55, 597-610.
36. Uranova, N., Vostrikov, V., Orlovskaya, D., et al (2004) Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium. Schizophrenia Research, 67, 269-275.
37. Velakoulis, D., Pantelis, C., McGorry, P. D., et al (1999) Hippocampal volume in first-episode psychoses and chronic schizophrenia - a high-resolution magnetic resonance imaging study. Archives of General Psychiatry, 56, 133-141.
38. Walker, J., Curtis, V. & Murray, R. M. (2002) Schizophrenia and bipolar disorder: similarities in pathogenic mechanisms but differences in neurodevelopment. International Clinical Psychophormocology, 17 (suppl. 3), S11-19.
39. Wellcome Department of Imaging Neuroscience (2003) Statistical Parametric Mapping. London: FIL Methods Group. http://www.fil.ion.ucl.ac.uk/spm
40. Woodruff, P. W., McManus, I. C. & David, A. S. (1995) Meta-analysis of corpus callosum size in schizophrenia. Journal of Neurology, Neurosurgery and Psychiatry, 58, 457-461.
41. Wright, I. C., Sharma, T., Ellison, Z. R., et al (1999) Supra-regional brain systems and the neuropathology of schizophrenia. Cerebral Cortex, 9, 366-378.
42. Wright, I. C., Rabe-Hesketh, S., Woodruff, P. W. R., et al (2000) Meta-analysis of regional brain volumes in schizophrenia. American Journal of Psychiatry, 157, 16-25.
43. Zipursky, R. B., Seeman, M. V., Bury, A., et al (1997) Deficits in gray matter volume are present in schizophrenia but not bipolar disorder. Schizophrenia Research, 26, 85-92.