Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms

American Journal of Psychiatry

Volumn 158, Issue 2, 2001, Pages 234-243

  Sigmundsson, T ^a   Suckling, J ^a   Maier, M ^a   Williams, S C R ^a   Bullmore, E T ^a   Greenwood, K E ^a   Fukuda, R ^a   Ron, M A ^a   Toone, B K ^a  

^a LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BASAL GANGLION; BRAIN SIZE; CINGULATE GYRUS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; INSULA; LIMBIC CORTEX; MAJOR CLINICAL STUDY; MALE; NEGATIVE SYNDROME; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; SCORING SYSTEM; SUBICULUM; TEMPORAL CORTEX; WHITE MATTER;

ADULT; BASAL GANGLIA; BRAIN MAPPING; FEMALE; FRONTAL LOBE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; TEMPORAL LOBE;

EID: 0035142528     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.158.2.234     Document Type: Article

References (57)

1. Cerebral ventricular size and cognitive impairment in chronic schizophrenics
2. Reduction of cortical volume in schizophrenia on magnetic resonance imaging
3. Widespread cerebral grey matter volume deficits in schizophrenia
4. Brain abnormality in schizophrenia
5. Meta-analysis of regional brain volumes in schizophrenia
6. The case for frontostriatal dysfunction in schizophrenia
7. Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: A magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins
8. Regional brain activity in chronic schizophrenic patients during the performance of a verbal fluency task
9. Does dysplasia cause anatomical dysconnectivity in schizophrenia?
10. Mapping of grey matter changes in schizoprenia
11. The schedule for the deficit syndrome: An instrument for research in schizophrenia
12. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia
13. Removal of extracerebral tissues in dual-echo magnetic resonance images via linear scale-space features
14. A modifed fuzzy clustering algorithm for operator independent brain tissue classification of dual echo MR images
15. Computerised brain tissue classification of magnetic resonance images: A new approach to the problem of partial volume artefact
16. Generic brain activation mapping in fMRh a nonparametric approach
17. Global, voxel and cluster tests, by theory and permutation for a difference between two groups of structural MR images of the brain
18. Voxel-based morphometry - The methods
19. The coefficient of racial likeness and the future of craniometry
20. Significance tests which may be applied to samples from any population
21. Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: A meta-analytic study
22. Proton magnetic resonance spectroscopy: An in vivo method of estimating hippocampal neuronal depletion in schizophrenia
23. Proton magnetic resonance spectroscopy of the temporal lobes in schizophrenics and normal controls
24. Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging
25. Abnormalities of the left temporal lobe and thought disorder in schizophrenia: A quantitative magnetic resonance imaging study
26. Volumetric MRI assessment of temporal lobe structures in schizophrenia
27. Asymmetries in the superior temporal lobe in male and female first-episode schizophrenic patients: Measures of the planum temporale and superior temporal gyrus by MRI
28. Effects of diagnosis, laterality, and gender on brain morphology in schizophrenia
29. Superior temporal gyrus volume in schizophrenia: A study using MRI morphometry assisted by surface rendering
30. Insula and aphasia
31. Neuroanatomical correlates of production deficits in severe Broca's aphasia
32. Lesion localization in acquired deficits of emotional expression and comprehension
33. Prenatal developemental disturbances in the limbic allocortex in schizophrenia
34. Temporal lobe abnormalities in multigenerational families with schizophrenia
35. Frontal-subcortical circuits and human behaviour
36. Cerebral blood flow and mental processes in schizophrenia
37. Dopaminergic modulation of impaired cognitive activation in the anterior cingulate cortex in schizophrenia
38. Neurobiological investigations in cingulate cortex of schizophrenic brain
39. Insula of the old world monkey, III: Efferent cortical output and comments on function
40. Large-scale neurocognitive networks and distributed processing for attention, language and memory
41. Supra-regional brain systems and the neuropathology of schizophrenia
42. Brain morphology and schizophrenia: A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures
43. Structural evaluation of the prefrontal cortex in schizophrenia
44. MRI white matter diffusion anisotrophy and PET metabolic rate in schizophrenia
45. Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs
46. Changes in caudate volume with neuroleptic treatment
47. Auditory hallucinations and the temporal cortical response to speech in schizophrenia: A functional magnetic resonance imaging study
48. Schizophrenia as an anomaly of cerebral asymmetry: A post-mortem study and a proposal concerning the genetic basis of the disease
49. Mathematical/computational challenges in creating deformable and probabilistic atlases of the human brain