A matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen fibrils

Human Mutation

Volumn 31, Issue 3, 2010, Pages 254-263

  Otten, Christiane ^a   Hansen, Uwe ^b   Talke, Anja ^c   Wagener, Raimund ^a   Paulsson, Mats ^a   Zaucke, Frank ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c ProteaImmun GmbH   (Germany)

Author keywords

Chondrodysplasia; Collagen fibril; Extracellular matrix; Matrilin; Osteoarthritis

Indexed keywords

AGGRECANASE 1; COLLAGEN FIBRIL; COLLAGEN TYPE 11; COLLAGEN TYPE 2; COLLAGEN TYPE 9; MATRILIN 3; METALLOPROTEINASE;

ARTICLE; BINDING AFFINITY; CARTILAGE; COLLAGEN SYNTHESIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE;

ADAM PROTEINS; ANIMALS; CARTILAGE; CELL LINE; CHONDROCYTES; COLLAGEN; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; MUTATION; OSTEOARTHRITIS; PROCOLLAGEN N-ENDOPEPTIDASE;

EID: 77149180728     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21182     Document Type: Article

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