Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7

Molecular Pharmacology

Volumn 77, Issue 3, 2010, Pages 459-468

  Niswender, Colleen M ^a   Johnson, Kari A ^a   Miller, Nicole R ^a   Ayala, Jennifer E ^a   Luo, Qingwei ^a   Williams, Richard ^a   Saleh, Samir ^b   Orton, Darren ^b,c   Weaver, C David ^a,b   Conn, P Jeffrey ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 6 (4 METHOXYPHENYL) 5 METHYL 3 (4 PYRIDINYL)ISOXAZOLO[4,5 C]PYRIDIN 4(5H) ONE; CALCIUM; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GLUTAMATE RECEPTOR 7; GLUTAMATE RECEPTOR ANTAGONIST; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; METABOTROPIC RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ANXIETY; ARTICLE; CALCIUM MOBILIZATION; CELL STRAIN BHK; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEPRESSION; DRUG TARGETING; EPILEPSY; HUMAN; HUMAN CELL; MOUSE; NEUROPHARMACOLOGY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; SYNAPSE; SYNAPTIC TRANSMISSION;

ALLOSTERIC REGULATION; ANIMALS; CELL LINE; CRICETINAE; DOWN-REGULATION; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SIGNAL TRANSDUCTION;

EID: 77149174796     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.058768     Document Type: Article

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