Tumor suppressor XIAP-associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression

Cancer

Volumn 116, Issue 5, 2010, Pages 1252-1263

  Tu, Shui Ping ^a,b   Sun, Yun Wei ^a,b   Cui, Jian Tao ^b   Zou, Bing ^b   Lin, Marie C M ^b   Gu, Qing ^b   Jiang, Shi Hu ^a   Kung, Hsiang Fu ^c   Korneluk, Robert G ^d   Wong, Benjamin C Y ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

Apoptosis; Cancer therapy; Colon cancer; Gene therapy; Tumor necrosis factor related apoptosis inducing ligand (TRAIL); XIAP associated factor 1 (XAF1)

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYTOCHROME C; INHIBITOR OF APOPTOSIS PROTEIN 1; SURVIVIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; XIAP ASSOCIATED FACTOR 1;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER SURVIVAL; CANCER THERAPY; CARCINOGENESIS; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; GENE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NICK END LABELING; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TUMOR REGRESSION; TUMOR XENOGRAFT; VIRUS PURIFICATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; COLONIC NEOPLASMS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77149161425     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24814     Document Type: Article

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