Structural characterization of human heme oxygenase-1 in complex with azole-based inhibitors

Journal of Inorganic Biochemistry

Volumn 104, Issue 3, 2010, Pages 324-330

  Rahman, Mona N ^a   Vlahakis, Jason Z ^a   Roman, Gheorghe ^a   Vukomanovic, Dragic ^a   Szarek, Walter A ^a   Nakatsu, Kanji ^a   Jia, Zongchao ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Heme oxygenase; HO 1; Inhibitor; Structure; X ray crystallography

Indexed keywords

AMINO ACID; ASPARTIC ACID; AZALANSTAT; COORDINATION COMPOUND; HEME; HEME OXYGENASE 1; HEME OXYGENASE INHIBITOR; HOLOENZYME; IMIDAZOLE; PYRROLE DERIVATIVE; TRIAZOLE; UNCLASSIFIED DRUG; WATER;

CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME PURIFICATION; ENZYME STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; PROTEIN DOMAIN; REVIEW; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANILINE COMPOUNDS; ANIMALS; AZOLES; CRYSTALLOGRAPHY, X-RAY; HEME OXYGENASE-1; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SULFIDES;

EID: 77149138802     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2009.10.011     Document Type: Review

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