Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 1, 2006, Pages 277-284

  Kinobe, Robert T ^a   Dercho, Ryan A ^a   Vlahakis, Jason Z ^a   Brien, James F ^a   Szarek, Walter A ^a   Nakatsu, Kanji ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CLOTRIMAZOLE; ECONAZOLE; FLUCONAZOLE; GRISEOFULVIN; HEME OXYGENASE; HEME OXYGENASE INHIBITOR; ISOCONAZOLE; KETOCONAZOLE; MICONAZOLE; NITRIC OXIDE SYNTHASE; PYRROLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; SULCONAZOLE; TERCONAZOLE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN MICROSOME; CATALYSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIFUNGAL AGENTS; ENZYME INHIBITORS; HEME OXYGENASE (DECYCLIZING); KETOCONAZOLE; KINETICS; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33749038678     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.102699     Document Type: Article

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