Elevated glucose impairs the endothelial cell response to shear stress

Cellular and Molecular Bioengineering

Volumn 2, Issue 4, 2009, Pages 533-543

  Brower, Jeremy B ^a   Targovnik, Jerome H ^a,b,c   Bowen, Benjamin P ^a   Caplan, Michael R ^a   Massia, Stephen P ^a  

^a Arizona State University   (United States)

^b CARL T HAYDEN VA MEDICAL CENTER   (United States)

^c BANNER GOOD SAMARITAN MEDICAL CENTER   (United States)

Author keywords

Cell shape; Diabetes complications; Glycosylation end products, advanced; Hemodynamics; Reactive oxygen species; Vascular endothelium

Indexed keywords

ADVANCED GLYCATION END PRODUCT; AMINOGUANIDINE; GLUCOSE; TEMPOL;

CELL CULTURE; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM CELL; FLUID FLOW; FORCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SHEAR STRESS;

EID: 77149136748     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-009-0080-8     Document Type: Conference Paper

References (59)

1. AI Barakat 2001 A model for shear stress-induced deformation of a flow sensor on the surface of vascular endothelial cells J. Theor. Biol. 210 221 236 10.1006/jtbi.2001.2290 (Pubitemid 32575063)
2. AI Barakat PF Davies 1998 Mechanisms of shear stress transmission and transduction in endothelial cells Chest 114 58S 63S 10.1378/chest.114.1- Supplement.58S
3. C Brindicci K Ito O Torre PJ Barnes SA Kharitonov 2009 Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients Chest 135 353 367 10.1378/chest.08-0964
4. M Brownlee 2005 The pathobiology of diabetic complications-a unifying mechanism Diabetes 54 1615 1625 10.2337/diabetes.54.6.1615 (Pubitemid 40770750)
5. AV Bui MH Nguyen 2004 Prediction of viscosity of glucose and calcium chloride solutions J. Food Eng. 62 345 349 10.1016/S0260-8774(03)00249-8
6. E Cagliero T Roth S Roy M Lorenzi 1991 Characteristics and mechanisms of high-glucose induced overexpression of basement-membrane components in cultured human endothelial-cells Diabetes 40 102 110 10.2337/diabetes.40.1.102
7. E Cagliero T Roth S Roy M Maiello M Lorenzi 1991 Expression of genes related to the extracellular-matrix in human endothelial-cells-differential modulation by elevated glucose-concentrations, phorbol esters, and camp J. Biol. Chem. 266 14244 14250
8. CG Caro JM Fitzgerald RC Schroter 1971 Atheroma and arterial wall shear-observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis Proc. R. Soc. Lond. B Biol. Sci. 177 109 159 10.1098/rspb.1971.0019
9. R Chibber PA Molinatti EM Kohner 1999 Intracellular protein glycation in cultured retinal capillary pericytes and endothelial cells exposed to high-glucose concentration Cell. Mol. Biol. 45 47 57
10. R Chibber PA Molinatti JSK Wong D Mirlees EM Kohner 1994 The effect of aminoguanidine and tolrestat on glucose toxicity in bovine retinal capillary pericytes Diabetes 43 758 763 10.2337/diabetes.43.6.758
11. P Connell T Walshe G Ferguson W Gao C O'Brien PA Cahill 2007 Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells Endothelium 14 17 24 10.1080/10623320601177213 (Pubitemid 46978766)
12. PF Davies 2009 Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology Nat. Clin. Pract. Cardiovasc. Med. 6 16 26 10.1038/ncpcardio1397
13. PF Davies DC Polacek CZ Shi BP Helmke 2002 The convergence of haemodynamics, genomics, and endothelial structure in studies of the focal origin of atherosclerosis Biorheology 39 299 306
14. PF Davies A Remuzzi EJ Gordon CF Dewey MA Gimbrone 1986 Turbulent fluid shear-stress induces vascular endothelial-cell turnover in vitro Proc. Natl. Acad. Sci. USA 83 2114 2117 10.1073/pnas.83.7.2114
15. PF Davies A Robotewskyj ML Griem 1994 Quantitative studies of endothelial-cell adhesion-directional remodeling of focal adhesion sites in response to flow forces J. Clin. Invest. 93 2031 2038 10.1172/JCI117197
16. PF Davies SC Tripathi 1993 Mechanical-stress mechanisms and the cell-an endothelial paradigm Circ. Res. 72 239 245
17. N Depaola MA Gimbrone PF Davies CF Dewey 1992 Vascular endothelium responds to fluid shear-stress gradients Arterioscler. Thromb. 12 1254 1257
18. CF Dewey SR Bussolari MA Gimbrone PF Davies 1981 The dynamic-response of vascular endothelial-cells to fluid shear-stress J. Biomech. Eng. Trans. ASME 103 177 185 10.1115/1.3138276
19. P Duann PK Datta C Pan JB Blumberg M Sharma EA Lianos 2006 Superoxide dismutase mimetic preserves the glomerular capillary permeability barrier to protein J. Pharmacol. Exp. Ther. 316 1249 1254 10.1124/jpet.105.092957 (Pubitemid 43345300)
20. RP Franke M Grafe H Schnittler D Seiffge C Mittermayer D Drenckhahn 1984 Induction of human vascular endothelial stress fibers by fluid shear-stress Nature 307 648 649 10.1038/307648a0
21. CG Galbraith R Skalak S Chien 1998 Shear stress induces spatial reorganization of the endothelial cell cytoskeleton Cell Motil. Cytoskeleton 40 317 330 10.1002/(SICI)1097-0169(1998)40:4<317::AID-CM1>3.0.CO;2-8 (Pubitemid 28364153)
22. LD Ghitescu A Gugliucci F Dumas 2001 Actin and annexins i and ii are among the main endothelial plasmalemma-associated proteins forming early glucose adducts in experimental diabetes Diabetes 50 1666 1674 10.2337/diabetes.50.7. 1666
23. MA Gimbrone 1999 Vascular endothelium, hemodynamic forces, and atherogenesis Am. J. Pathol. 155 1 5
24. A Goldin JA Beckman AM Schmidt MA Creager 2006 Advanced glycation end products-sparking the development of diabetic vascular injury Circulation 114 597 605 10.1161/CIRCULATIONAHA.106.621854 (Pubitemid 44199649)
25. AI Gottlieb BL Langille MKK Wong DW Kim 1991 Structure and function of the endothelial cytoskeleton Lab. Invest. 65 123 137
26. MJD Griffiths M Messent RJ Macallister TW Evans 1993 Aminoguanidine selectively inhibits inducible nitric-oxide synthase Br. J. Pharmacol. 110 963 968
27. AL Hazel TJ Pedley 2000 Vascular endothelial cells minimize the total force on their nuclei Biophys. J. 78 47 54 10.1016/S0006-3495(00)76571-4
28. BP Helmke 2005 Molecular control of cytoskeletal mechanics by hemodynamic forces Physiology 20 43 53 10.1152/physiol.00040.2004
29. K Higai A Shimamura K Matsumoto 2006 Amadori-modified glycated albumin predominantly induces e-selectin expression on human umbilical vein endothelial cells through NADPH oxidase activation Clin. Chim. Acta 367 137 143 10.1016/j.cca.2005.12.008
30. S Kado T Wakatsuki M Yamamoto N Nagata 2001 Expression of intercellular adhesion molecule-1 induced by high glucose concentrations in human aortic endothelial cells Life Sci. 68 727 737 10.1016/S0024-3205(00)00968-1 (Pubitemid 32168004)
31. GB Kowalsky FJ Byfield I Levitan 2008 oxLDL facilitates flow-induced realignment of aortic endothelial cells Am. J. Physiol. Cell Physiol. 295 C332 C340 10.1152/ajpcell.00335.2007 (Pubitemid 352755779)
32. DN Ku DP Giddens CK Zarins S Glagov 1985 Pulsatile flow and atherosclerosis in the human carotid bifurcation-positive correlation between plaque location and low and oscillating shear-stress Arteriosclerosis 5 293 302
33. BL Langille SL Adamson 1981 Relationship between blood-flow direction and endothelial-cell orientation at arterial branch sites in rabbits and mice Circ. Res. 48 481 488
34. YSJ Li JH Haga S Chien 2005 Molecular basis of the effects of shear stress on vascular endothelial cells J. Biomech. 38 1949 1971 10.1016/j.jbiomech.2004.09.030 (Pubitemid 41111740)
35. PJ Mack MR Kaazempur-Mofrad H Karcher RT Lee RD Kamm 2004 Force-induced focal adhesion translocation: effects of force amplitude and frequency Am. J. Physiol. Cell Physiol. 287 C954 C962 10.1152/ajpcell.00567.2003 (Pubitemid 39238319)
36. AM Malek S Izumo SL Alper 1999 Modulation by pathophysiological stimuli of the shear stress-induced up-regulation of endothelial nitric oxide synthase expression in endothelial cells Neurosurgery 45 334 344 10.1097/00006123- 199908000-00028 (Pubitemid 29395111)
37. EJ Menzel J Neumuller G Sengoelge R Reihsner 1997 Effects of aminoguanidine on adhesion molecule expression of human endothelial cells Pharmacology 55 126 135 10.1159/000139520
38. S Mohan M Hamuro K Koyoma GP Sorescu HJ Jo M Natarajan 2003 High glucose induced nf-kb DNA-binding activity in haec is maintained under low shear stress but inhibited under high shear stress: role of nitric oxide Atherosclerosis 171 225 234 10.1016/j.atherosclerosis.2003.08.023 (Pubitemid 37486074)
39. T Nagel N Resnick CF Dewey MA Gimbrone 1999 Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors Arterioscler. Thromb. Vasc. Biol. 19 1825 1834
40. L Piconi L Quagliaro R Assaloni R Da Ros A Maier G Zuodar A Ceriello 2006 Constant and intermittent high glucose enhances endothelial cell apoptosis through mitochondrial superoxide overproduction Diabetes Metab. Res. Rev. 22 198 203 10.1002/dmrr.613 (Pubitemid 43805400)
41. C Polytarchou E Papadimitriou 2005 Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity Eur. J. Pharmacol. 510 31 38 10.1016/j.ejphar.2005.01.004 (Pubitemid 40312387)
42. MA Reidy BL Langille 1980 The effect of local blood-flow patterns on endothelial-cell morphology Exp. Mol. Pathol. 32 276 289 10.1016/0014-4800(80) 90061-1
43. WB Robertson JP Strong 1968 Atherosclerosis in persons with hypertension and diabetes mellitus Lab. Invest. 18 538 551
44. T Roth F Podesta MA Stepp D Boeri M Lorenzi 1993 Integrin overexpression induced by high glucose and by human diabetes-potential pathway to cell dysfunction in diabetic microangiopathy Proc. Natl. Acad. Sci. USA 90 9640 9644 10.1073/pnas.90.20.9640 (Pubitemid 23315841)
45. A Salameh M Zinn S Dhein 1997 High d-glucose induces alterations of endothelial cell structure in a cell-culture model J. Cardiovasc. Pharmacol. 30 182 190 10.1097/00005344-199708000-00006 (Pubitemid 27524518)
46. T Sampietro S Lenzi P Cecchetti O Giampietro L Cruschelli R Navalesi 1986 Nonenzymatic glycation of human-platelet membrane-proteins in vitro and in vivo Clin. Chem. 32 1328 1331
47. A Sank D Wei J Reid D Ertl M Nimni F Weaver A Yellin TL Tuan 1994 Human endothelial-cells are defective in diabetic vascular-disease J. Surg. Res. 57 647 653 10.1006/jsre.1994.1195
48. M Sato MJ Levesque RM Nerem 1987 Micropipette aspiration of cultured bovine aortic endothelial-cells exposed to shear-stress Arteriosclerosis 7 276 286
49. JB Silkworth WE Stehbens 1975 Shape of endothelial cells in en-face preparations of rabbit blood-vessels Angiology 26 474 487 10.1177/ 000331977502600607
50. D Tang C Yang S Mondal F Liu G Canton TS Hatsukami C Yuan 2008 A negative correlation between human carotid atherosclerotic plaque progression and plaque wall stress: in vivo MRI-based 2d/3d FSI models J. Biomech. 41 727 736 10.1016/j.jbiomech.2007.11.026
51. MM Thi JM Tarbell S Weinbaum DC Spray 2004 The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "Bumper-car" Model Proc. Natl. Acad. Sci. USA 101 16483 16488 10.1073/pnas.0407474101 (Pubitemid 39557739)
52. E Tzima MA del Pozo SJ Shattil S Chien MA Schwartz 2001 Activation of integrins in endothelial cells by fluid shear stress mediates rho-dependent cytoskeletal alignment EMBO J. 20 4639 4647 10.1093/emboj/20.17.4639 (Pubitemid 32848617)
53. E Tzima M Irani-Tehrani WB Kiosses E Dejana DA Schultz B Engelhardt GY Cao H DeLisser MA Schwartz 2005 A mechanosensory complex that mediates the endothelial cell response to fluid shear stress Nature 437 426 431 10.1038/nature03952 (Pubitemid 41613506)
54. VJ Vigorita GW Moore GM Hutchins 1980 Absence of correlation between coronary arterial atherosclerosis and severity or duration of diabetes-mellitus of adult onset Am. J. Cardiol. 46 535 542 10.1016/0002-9149(80)90500-7 (Pubitemid 10009804)
55. C Wadham A Parker LJ Wang P Xia 2007 High glucose attenuates protein s-nitrosylation in endothelial cells-role of oxidative stress Diabetes 56 2715 2721 10.2337/db06-1294 (Pubitemid 350044914)
56. AR Wechezak TN Wight RF Viggers LR Sauvage 1989 Endothelial adherence under shear-stress is dependent upon microfilament reorganization J. Cell. Physiol. 139 136 146 10.1002/jcp.1041390120 (Pubitemid 19120281)
57. H Wessells TH Teal K Engel CJ Sullivan B Gallis KB Tran K Chitaley 2006 Fluid shear stress-induced nitric oxide production in human cavernosal endothelial cells: inhibition by hyperglycaemia BJU Int. 97 1047 1052 10.1111/j.1464-410X.2006.06059.x
58. CR White JA Frangos 2007 The shear stress of it all: the cell membrane and mechanochemical transduction Philos. Trans. R. Soc. Lond. B Biol. Sci. 362 1459 1467 10.1098/rstb.2007.2128 (Pubitemid 47195034)
59. Y Yao A Rabodzey CF Dewey 2007 Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress Am. J. Physiol. Heart Circ. Physiol. 293 H1023 H1030 10.1152/ajpheart.00162.2007 (Pubitemid 47254201)