메뉴 건너뛰기




Volumn 19, Issue 8, 1999, Pages 1825-1834

Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors

Author keywords

C Fos; C Jun; Disturbed flow; Early growth response 1; Nuclear factor B

Indexed keywords

IMMEDIATE EARLY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ONCOPROTEIN; PROTEIN C FOS; TRANSCRIPTION FACTOR;

EID: 0032769546     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.8.1825     Document Type: Article
Times cited : (309)

References (49)
  • 1
    • 0030800058 scopus 로고    scopus 로고
    • Hemodynamics, endothelial gene expression, and atherogenesis
    • The Fourth Saratoga International Conference on Atherosclerosis
    • Gimbrone MA Jr, Resnick N, Nagel T, Khachigian LM, Collins T, Topper JN. Hemodynamics, endothelial gene expression, and atherogenesis, in The Fourth Saratoga International Conference on Atherosclerosis. Ann N Y Acad Sci. 1997;811:1-11.
    • (1997) Ann N Y Acad Sci. , vol.811 , pp. 1-11
    • Gimbrone M.A., Jr.1    Resnick, N.2    Nagel, T.3    Khachigian, L.M.4    Collins, T.5    Topper, J.N.6
  • 2
    • 0344965953 scopus 로고
    • A hemodynamic concept of atherosclerosis, with particular reference to coronary occlusion
    • Texon M. A hemodynamic concept of atherosclerosis, with particular reference to coronary occlusion. Arch Intern Med. 1957;99:418-427.
    • (1957) Arch Intern Med. , vol.99 , pp. 418-427
    • Texon, M.1
  • 3
    • 0344534976 scopus 로고
    • Experimental atherosclerosis produced by alteration of blood vessel configuration
    • Imparato AM, Lord JW Jr, Texon M, Helpern M. Experimental atherosclerosis produced by alteration of blood vessel configuration. Surg Forum. 1961;12:245-247.
    • (1961) Surg Forum , vol.12 , pp. 245-247
    • Imparato, A.M.1    Lord J.W., Jr.2    Texon, M.3    Helpern, M.4
  • 4
    • 0014607162 scopus 로고
    • Experimental investigations of the role of hemodynamic factors in formation of intimal changes
    • Gyurko G, Szabo M. Experimental investigations of the role of hemodynamic factors in formation of intimal changes. Surgery. 1969;66: 871-874.
    • (1969) Surgery , vol.66 , pp. 871-874
    • Gyurko, G.1    Szabo, M.2
  • 6
    • 0018183008 scopus 로고
    • Experimental evaluation of streamline patterns and separated flows in a series of branching vessels with implications for atherosclerosis and thrombosis
    • el-Masry OA, Feuerstein IA, Round GF. Experimental evaluation of streamline patterns and separated flows in a series of branching vessels with implications for atherosclerosis and thrombosis. Circ Res. 1978;43: 608-618.
    • (1978) Circ Res. , vol.43 , pp. 608-618
    • El-Masry, O.A.1    Feuerstein, I.A.2    Round, G.F.3
  • 7
    • 0022911406 scopus 로고
    • Microscopic structure of disturbed flows in the arterial and venous systems, and its implication in the localization of vascular diseases
    • Karino T. Microscopic structure of disturbed flows in the arterial and venous systems, and its implication in the localization of vascular diseases. Int Angiol. 1986;5:297-313.
    • (1986) Int Angiol. , vol.5 , pp. 297-313
    • Karino, T.1
  • 8
    • 0027691227 scopus 로고
    • The role of fluid mechanics in the localization and detection of atherosclerosis
    • Giddens DP, Zarins CK, Glagov S. The role of fluid mechanics in the localization and detection of atherosclerosis. J Biomech Eng. 1993;115: 588-594.
    • (1993) J Biomech Eng. , vol.115 , pp. 588-594
    • Giddens, D.P.1    Zarins, C.K.2    Glagov, S.3
  • 9
    • 0016661285 scopus 로고
    • Calculations of pulsatile flow through a branch: Implications for the hemodynamics of atherogenesis
    • Friedman MH, O'Brien V, Ehrlich LW. Calculations of pulsatile flow through a branch: implications for the hemodynamics of atherogenesis. Circ Res. 1975;36:277-285.
    • (1975) Circ Res. , vol.36 , pp. 277-285
    • Friedman, M.H.1    O'Brien, V.2    Ehrlich, L.W.3
  • 10
    • 0025719973 scopus 로고
    • Pulsatile non-Newtonian flow characteristics in a three-dimensional human carotid bifurcation model
    • Perktold K, Resch M, Florian H. Pulsatile non-Newtonian flow characteristics in a three-dimensional human carotid bifurcation model. J Biomech Eng. 1991;113:464-475.
    • (1991) J Biomech Eng. , vol.113 , pp. 464-475
    • Perktold, K.1    Resch, M.2    Florian, H.3
  • 11
    • 0017610474 scopus 로고
    • Scanning electron microscopy of arteries. The morphology of aortic endothelium in haemodynamically stressed areas associated with branches
    • Reidy MA, Bowyer DE. Scanning electron microscopy of arteries. The morphology of aortic endothelium in haemodynamically stressed areas associated with branches. Atherosclerosis. 1977;26:181-194.
    • (1977) Atherosclerosis. , vol.26 , pp. 181-194
    • Reidy, M.A.1    Bowyer, D.E.2
  • 12
    • 0022449843 scopus 로고
    • Correlation of endothelial cell shape and wall shear stress in a stenosed dog aorta
    • Levesque MJ, Liepsch D, Moravec S, Nerem RM. Correlation of endothelial cell shape and wall shear stress in a stenosed dog aorta. Arteriosclerosis. 1986;6:220-229.
    • (1986) Arteriosclerosis , vol.6 , pp. 220-229
    • Levesque, M.J.1    Liepsch, D.2    Moravec, S.3    Nerem, R.M.4
  • 13
    • 0026911040 scopus 로고
    • Endothelial cell morphometry of atherosclerotic lesions and flow profiles at aortic bifurcations in cholesterol fed rabbits
    • Okano M, Yoshida Y. Endothelial cell morphometry of atherosclerotic lesions and flow profiles at aortic bifurcations in cholesterol fed rabbits. J Biomech Eng. 1992;114:301-308.
    • (1992) J Biomech Eng. , vol.114 , pp. 301-308
    • Okano, M.1    Yoshida, Y.2
  • 14
    • 1842330850 scopus 로고    scopus 로고
    • Biomechanical activation: An emerging paradigm in endothelial adhesion biology
    • Gimbrone MA Jr, Nagel T, Topper JN. Biomechanical activation: an emerging paradigm in endothelial adhesion biology. J Clin Invest. 1997; 99:1809-1813.
    • (1997) J Clin Invest. , vol.99 , pp. 1809-1813
    • Gimbrone M.A., Jr.1    Nagel, T.2    Topper, J.N.3
  • 16
    • 0026444077 scopus 로고
    • Vascular endothelium responds to fluid shear stress gradients
    • Correction. 1993;13:465
    • DePaola N, Gimbrone MA Jr, Davies PF, Dewey CF Jr. Vascular endothelium responds to fluid shear stress gradients. Arterioscler Thromb. 1992;12:1254-1257. (Correction. 1993;13:465.)
    • (1992) Arterioscler Thromb. , vol.12 , pp. 1254-1257
    • DePaola, N.1    Gimbrone M.A., Jr.2    Davies, P.F.3    Dewey C.F., Jr.4
  • 17
    • 0031456799 scopus 로고    scopus 로고
    • Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle
    • Tardy Y, Resnick N, Nagel T, Gimbrone MA Jr, Dewey CF Jr. Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle. Arterioscler Thromb Vasc Biol. 1997; 17:3102-3106.
    • (1997) Arterioscler Thromb Vasc Biol. , vol.17 , pp. 3102-3106
    • Tardy, Y.1    Resnick, N.2    Nagel, T.3    Gimbrone M.A., Jr.4    Dewey C.F., Jr.5
  • 18
    • 0027529593 scopus 로고
    • Mechanical stress mechanisms and the cell: An endothelial paradigm
    • Davies PF, Tripathi SC. Mechanical stress mechanisms and the cell: an endothelial paradigm. Circ Res. 1993;72:239-245.
    • (1993) Circ Res. , vol.72 , pp. 239-245
    • Davies, P.F.1    Tripathi, S.C.2
  • 19
    • 0029132731 scopus 로고
    • Hemodynamic forces are complex regulators of endothelial gene expression
    • Resnick N, Gimbrone MA Jr. Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J. 1995;9:874-882.
    • (1995) FASEB J. , vol.9 , pp. 874-882
    • Resnick, N.1    Gimbrone M.A., Jr.2
  • 20
    • 0027231432 scopus 로고
    • Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element
    • Correction. 1993;90:7908
    • Resnick N, Collins T, Atkinson W, Bonthron DT, Dewey CF Jr, Gimbrone MA Jr. Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sci USA. 1993;90:4591-4595. (Correction. 1993;90:7908.)
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4591-4595
    • Resnick, N.1    Collins, T.2    Atkinson, W.3    Bonthron, D.T.4    Dewey C.F., Jr.5    Gimbrone M.A., Jr.6
  • 21
    • 0028982830 scopus 로고
    • Nuclear factor-κB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress
    • Khachigian LM, Resnick N, Gimbrone MA Jr, Collins T. Nuclear factor-κB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J Clin Invest. 1995;96:1169-1175.
    • (1995) J Clin Invest. , vol.96 , pp. 1169-1175
    • Khachigian, L.M.1    Resnick, N.2    Gimbrone M.A., Jr.3    Collins, T.4
  • 22
    • 0031458309 scopus 로고    scopus 로고
    • Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter
    • Khachigian LM, Anderson KR, Halnon NJ, Gimbrone MA Jr, Resnick N, Collins T. Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter. Arterioscler Thromb Vasc Biol. 1997;17: 2280-2286.
    • (1997) Arterioscler Thromb Vasc Biol. , vol.17 , pp. 2280-2286
    • Khachigian, L.M.1    Anderson, K.R.2    Halnon, N.J.3    Gimbrone M.A., Jr.4    Resnick, N.5    Collins, T.6
  • 23
    • 0029147580 scopus 로고
    • The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression
    • Shyy JY, Lin MC, Han J, Lu Y, Petrime M, Chien S. The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression. Proc Natl Acad Sci USA. 1995;92:8069-8073.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8069-8073
    • Shyy, J.Y.1    Lin, M.C.2    Han, J.3    Lu, Y.4    Petrime, M.5    Chien, S.6
  • 24
    • 20644431594 scopus 로고    scopus 로고
    • Negative transcriptional regulation of the VCAM-1 gene by fluid shear stress in murine endothelial cells
    • Korenaga R, Ando J, Kosaki K, Isshiki M, Takada Y, Kamiya A. Negative transcriptional regulation of the VCAM-1 gene by fluid shear stress in murine endothelial cells. Am J Physiol. 1997;273:C1506-C1515.
    • (1997) Am J Physiol. , vol.273
    • Korenaga, R.1    Ando, J.2    Kosaki, K.3    Isshiki, M.4    Takada, Y.5    Kamiya, A.6
  • 25
    • 0016906538 scopus 로고
    • Culture of vascular endothelium
    • Spaet T, ed. New York: Grune & Stratton, Inc;
    • Gimbrone MA Jr. Culture of vascular endothelium. In: Spaet T, ed. Progress in Hemostasis and Thrombosis. Vol 3. New York: Grune & Stratton, Inc; 1976:1-28.
    • (1976) Progress in Hemostasis and Thrombosis , vol.3 , pp. 1-28
    • Gimbrone M.A., Jr.1
  • 28
    • 0021177003 scopus 로고
    • Secondary flow and turbulence in a cone-and-plate device
    • Sdougos HP, Bussolari SR, Dewey CF Jr. Secondary flow and turbulence in a cone-and-plate device. J Fluid Mech. 1984;138:379-404.
    • (1984) J Fluid Mech. , vol.138 , pp. 379-404
    • Sdougos, H.P.1    Bussolari, S.R.2    Dewey C.F., Jr.3
  • 30
    • 0030818274 scopus 로고    scopus 로고
    • Inducible expression of Egr-1-dependent genes. A paradigm of transcriptional activation in vascular endothelium
    • Khachigian LM, Collins T. Inducible expression of Egr-1-dependent genes. A paradigm of transcriptional activation in vascular endothelium. Circ Res. 1997;81:457-461.
    • (1997) Circ Res. , vol.81 , pp. 457-461
    • Khachigian, L.M.1    Collins, T.2
  • 31
    • 0025720735 scopus 로고
    • The role of Jun. Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel P, Karin M. The role of Jun. Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta. 1991;1072: 129-157.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 32
    • 0345367786 scopus 로고    scopus 로고
    • Endothelial Cx43 regulation in disturbed flows in vitro
    • DePaola N, Davies PF, Polacek D. Endothelial Cx43 regulation in disturbed flows in vitro. Microcirculation. 1997;4:167.
    • (1997) Microcirculation , vol.4 , pp. 167
    • DePaola, N.1    Davies, P.F.2    Polacek, D.3
  • 33
    • 0032556026 scopus 로고    scopus 로고
    • Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed
    • Gabriels JE, Paul DL. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ Res. 1998;83:636-643.
    • (1998) Circ Res. , vol.83 , pp. 636-643
    • Gabriels, J.E.1    Paul, D.L.2
  • 34
    • 0019393526 scopus 로고
    • Influence of molecular charge upon the endocytosis and intracellular fate of peroxidase activity in cultured arterial endothelium
    • Davies PF, Rennke HG, Cotran RS. Influence of molecular charge upon the endocytosis and intracellular fate of peroxidase activity in cultured arterial endothelium. J Cell Sci. 1981;49:69-86.
    • (1981) J Cell Sci. , vol.49 , pp. 69-86
    • Davies, P.F.1    Rennke, H.G.2    Cotran, R.S.3
  • 35
    • 0029583932 scopus 로고
    • A mechanism for heterogeneous endothelial responses to flow in vivo and in vitro
    • Davies PF, Mundel T, Barbee KA. A mechanism for heterogeneous endothelial responses to flow in vivo and in vitro. J Biomech. 1995;28: 1553-1560.
    • (1995) J Biomech. , vol.28 , pp. 1553-1560
    • Davies, P.F.1    Mundel, T.2    Barbee, K.A.3
  • 36
    • 0028291843 scopus 로고
    • Stimulation of transcription factors NF-κB and AP1 in endothelial cells subjected to shear stress
    • Lan Q, Mercurius KO, Davies PF. Stimulation of transcription factors NF-κB and AP1 in endothelial cells subjected to shear stress. Biochem Biophys Res Commun. 1994;201:950-956.
    • (1994) Biochem Biophys Res Commun. , vol.201 , pp. 950-956
    • Lan, Q.1    Mercurius, K.O.2    Davies, P.F.3
  • 37
    • 85038150352 scopus 로고    scopus 로고
    • Induction of Egr-1 gene expression and nuclear localization in cultured vascular endothelial cells exposed to laminar shear stress
    • Nagel T, Anderson KR, Topper JN, Gimbrone MA Jr. Induction of Egr-1 gene expression and nuclear localization in cultured vascular endothelial cells exposed to laminar shear stress. Microcirculation. 1997;4:A167.
    • (1997) Microcirculation , vol.4
    • Nagel, T.1    Anderson, K.R.2    Topper, J.N.3    Gimbrone M.A., Jr.4
  • 38
    • 0027505606 scopus 로고
    • Pulsatile and steady flow induces c-fos expression in human endothelial cells
    • Hsieh H J, Li NQ, Frangos JA. Pulsatile and steady flow induces c-fos expression in human endothelial cells. J Cell Physiol. 1993;154:143-151.
    • (1993) J Cell Physiol. , vol.154 , pp. 143-151
    • Hsieh, H.J.1    Li, N.Q.2    Frangos, J.A.3
  • 39
    • 0027376140 scopus 로고
    • Fluid shear stress induces synthesis and nuclear localization of c-fos in cultured human endothelial cells
    • Ranjan V, Diamond SL. Fluid shear stress induces synthesis and nuclear localization of c-fos in cultured human endothelial cells. Biochem Biophys Res Commun. 1993;196:79-84.
    • (1993) Biochem Biophys Res Commun. , vol.196 , pp. 79-84
    • Ranjan, V.1    Diamond, S.L.2
  • 40
    • 13344284663 scopus 로고    scopus 로고
    • Fluid shear stress induction of the transcriptional activator c-fos in human and bovine endothelial cells, hela, and chinese hamster ovary cells
    • Ranjan V, Waterbury R, Xiao ZH, Diamond SL. Fluid shear stress induction of the transcriptional activator c-fos in human and bovine endothelial cells, hela, and chinese hamster ovary cells. Biotechnol Bioeng. 1996;49:383-390.
    • (1996) Biotechnol Bioeng. , vol.49 , pp. 383-390
    • Ranjan, V.1    Waterbury, R.2    Xiao, Z.H.3    Diamond, S.L.4
  • 42
    • 0025770579 scopus 로고
    • Effects of pulsatile flow on cultured vascular endothelial cell morphology
    • Helmlinger G, Geiger RV, Schreck S, Nerem RM. Effects of pulsatile flow on cultured vascular endothelial cell morphology. J Biomech Eng. 1991;113:123-131.
    • (1991) J Biomech Eng. , vol.113 , pp. 123-131
    • Helmlinger, G.1    Geiger, R.V.2    Schreck, S.3    Nerem, R.M.4
  • 43
    • 0021253310 scopus 로고
    • Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells
    • Davies PF, Dewey CF Jr, Bussolari SR, Gordon EJ, Gimbrone MA Jr. Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells. J Clin Invest. 1984;73:1121-1129.
    • (1984) J Clin Invest. , vol.73 , pp. 1121-1129
    • Davies, P.F.1    Dewey C.F., Jr.2    Bussolari, S.R.3    Gordon, E.J.4    Gimbrone M.A., Jr.5
  • 44
    • 0028837365 scopus 로고
    • Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ
    • Helmlinger G, Berk BC, Nerem RM. Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ. Am J Physiol. 1995;269:C367-C375.
    • (1995) Am J Physiol. , vol.269
    • Helmlinger, G.1    Berk, B.C.2    Nerem, R.M.3
  • 45
    • 0032104153 scopus 로고    scopus 로고
    • Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: Role of a superoxide-producing NADH oxidase
    • De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Cire Res. 1998;82:1094-1101.
    • (1998) Cire Res. , vol.82 , pp. 1094-1101
    • De Keulenaer, G.W.1    Chappell, D.C.2    Ishizaka, N.3    Nerem, R.M.4    Alexander, R.W.5    Griendling, K.K.6
  • 46
    • 0032559834 scopus 로고    scopus 로고
    • Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium
    • Chappell DC, Varner SE, Nerem RM, Medford RM, Alexander RW. Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium. Circ Res. 1998;82:532-539.
    • (1998) Circ Res. , vol.82 , pp. 532-539
    • Chappell, D.C.1    Varner, S.E.2    Nerem, R.M.3    Medford, R.M.4    Alexander, R.W.5
  • 47
    • 0013689056 scopus 로고    scopus 로고
    • NO regulates PDGF-A and MCP-1 expression induced by temporal gradients in shear stress in human endothelial cells
    • Frangos JA, Bao XP. NO regulates PDGF-A and MCP-1 expression induced by temporal gradients in shear stress in human endothelial cells. Jpn J Pharmacol. 1997;75:31.
    • (1997) Jpn J Pharmacol. , vol.75 , pp. 31
    • Frangos, J.A.1    Bao, X.P.2
  • 48
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
    • Traub O, Berk BC. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol. 1998;18:677-685.
    • (1998) Arterioscler Thromb Vasc Biol. , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 49
    • 0002548116 scopus 로고    scopus 로고
    • Hemodynamics and endothelial phenotype: New insights into the modulation of vascular gene expression by fluid mechanical stimuli
    • Lelkes PI, ed. London: Harwood Academic Press: in press
    • Topper JN, Gimbrone MA Jr. Hemodynamics and endothelial phenotype: new insights into the modulation of vascular gene expression by fluid mechanical stimuli. In: Lelkes PI, ed. Endothelium and Mechanical Forces. London: Harwood Academic Press; 1999: in press.
    • (1999) Endothelium and Mechanical Forces
    • Topper, J.N.1    Gimbrone M.A., Jr.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.