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Volumn 45, Issue 2, 1999, Pages 334-345

Modulation by pathophysiological stimuli of the shear stress-induced up- regulation of endothelial nitric oxide synthase expression in endothelial cells

Author keywords

Atherosclerosis; Flow; Fluid mechanics; Hyperglycemia; Hypoxia; Mechanical stress; Protein kinase

Indexed keywords

GLUCOSE; MESSENGER RNA; NITRIC OXIDE SYNTHASE;

EID: 0032818222     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-199908000-00028     Document Type: Article
Times cited : (85)

References (64)
  • 1
    • 0027454162 scopus 로고
    • Morphological and proliferative responses of endothelial cells to hydrostatic pressure: Role of fibroblast growth factor
    • Acevedo AD, Bowser SS, Gerritsen ME, Bizios R: Morphological and proliferative responses of endothelial cells to hydrostatic pressure: Role of fibroblast growth factor. J Cell Physiol 157: 603-614, 1993.
    • (1993) J Cell Physiol , vol.157 , pp. 603-614
    • Acevedo, A.D.1    Bowser, S.S.2    Gerritsen, M.E.3    Bizios, R.4
  • 2
    • 0025247921 scopus 로고
    • Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries
    • Asakura T, Karino T: Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries. Circ Res 66:1045-1066, 1990.
    • (1990) Circ Res , vol.66 , pp. 1045-1066
    • Asakura, T.1    Karino, T.2
  • 3
    • 0029914567 scopus 로고    scopus 로고
    • Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells
    • Ayajiki K, Kindermann M, Hecker M, Fleming I, Busse R: Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells. Circ Res 78:750-758, 1996.
    • (1996) Circ Res , vol.78 , pp. 750-758
    • Ayajiki, K.1    Kindermann, M.2    Hecker, M.3    Fleming, I.4    Busse, R.5
  • 4
    • 0028261621 scopus 로고
    • Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits
    • Cayatte AJ, Palacino JJ, Horten K, Cohen RA: Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler Thromb 14:753-759, 1994.
    • (1994) Arterioscler Thromb , vol.14 , pp. 753-759
    • Cayatte, A.J.1    Palacino, J.J.2    Horten, K.3    Cohen, R.A.4
  • 5
    • 0028818271 scopus 로고
    • Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions
    • Clària J, Serhan CN: Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci U S A 92:9475-9479, 1995.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9475-9479
    • Clària, J.1    Serhan, C.N.2
  • 6
    • 0029987385 scopus 로고    scopus 로고
    • Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress
    • Corson MA, James NL, Latta SE, Nerem RM, Berk BC, Harrison DG: Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress. Circ Res 79:984-991, 1996.
    • (1996) Circ Res , vol.79 , pp. 984-991
    • Corson, M.A.1    James, N.L.2    Latta, S.E.3    Nerem, R.M.4    Berk, B.C.5    Harrison, D.G.6
  • 7
    • 0029072762 scopus 로고
    • Flow-mediated endothelial mechanotransduction
    • Davies PF: Flow-mediated endothelial mechanotransduction. Physiol Rev 75:519-560, 1995.
    • (1995) Physiol Rev , vol.75 , pp. 519-560
    • Davies, P.F.1
  • 8
    • 0031459881 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of nuclear factor-κB-dependent transcription involves direct interference with transactivation
    • De Bosscher K, Schmitz ML, Vanden Berghe W, Plaisance S, Fiers W, Haegeman G: Glucocorticoid-mediated repression of nuclear factor-κB-dependent transcription involves direct interference with transactivation. Proc Natl Acad Sci U S A 94:13504-13509, 1997.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13504-13509
    • De Bosscher, K.1    Schmitz, M.L.2    Vanden Berghe, W.3    Plaisance, S.4    Fiers, W.5    Haegeman, G.6
  • 9
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr, Shin WS, Liao JK: Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 96:60-68, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone M.A., Jr.6    Shin, W.S.7    Liao, J.K.8
  • 11
    • 0031893415 scopus 로고    scopus 로고
    • Regulation of the cerebral circulation: Role of endothelium and potassium channels
    • Faraci FM, Heistad DD: Regulation of the cerebral circulation: Role of endothelium and potassium channels. Physiol Rev 78: 53-97, 1998.
    • (1998) Physiol Rev , vol.78 , pp. 53-97
    • Faraci, F.M.1    Heistad, D.D.2
  • 12
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376, 1980.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 13
    • 0027336672 scopus 로고
    • Mechanisms of nitrosothiol-induced anti-mitogenesis in aortic smooth muscle cells
    • Garg UC, Hassid A: Mechanisms of nitrosothiol-induced anti-mitogenesis in aortic smooth muscle cells. Eur J Pharmacol 237:243-249, 1993.
    • (1993) Eur J Pharmacol , vol.237 , pp. 243-249
    • Garg, U.C.1    Hassid, A.2
  • 14
    • 0027691227 scopus 로고
    • The role of fluid mechanics in the localization and detection of atherosclerosis
    • Giddens DP, Zarins CK, Glagov S: The role of fluid mechanics in the localization and detection of atherosclerosis. J Biomech Eng 115:588-594, 1993.
    • (1993) J Biomech Eng , vol.115 , pp. 588-594
    • Giddens, D.P.1    Zarins, C.K.2    Glagov, S.3
  • 15
    • 2642601112 scopus 로고    scopus 로고
    • Biomechanical activation: An emerging paradigm in endothelial adhesion biology
    • Gimbrone MA Jr, Nagel T, Topper JN: Biomechanical activation: An emerging paradigm in endothelial adhesion biology. J Clin Invest 100[Suppl]:S61-S65, 1997.
    • (1997) J Clin Invest , vol.100 , Issue.SUPPL.
    • Gimbrone M.A., Jr.1    Nagel, T.2    Topper, J.N.3
  • 17
    • 0031004009 scopus 로고    scopus 로고
    • In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis
    • Gnasso A, Irace C, Carallo C, De Franceschi MS, Motti C, Mattioli PL, Pujia A: In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis. Stroke 28:993-998, 1997.
    • (1997) Stroke , vol.28 , pp. 993-998
    • Gnasso, A.1    Irace, C.2    Carallo, C.3    De Franceschi, M.S.4    Motti, C.5    Mattioli, P.L.6    Pujia, A.7
  • 18
    • 0031464761 scopus 로고    scopus 로고
    • Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia
    • Graier WF, Posch K, Wascher TC, Kostner GM: Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia. Horm Metab Res 29:622-626, 1997.
    • (1997) Horm Metab Res , vol.29 , pp. 622-626
    • Graier, W.F.1    Posch, K.2    Wascher, T.C.3    Kostner, G.M.4
  • 19
    • 0032478310 scopus 로고    scopus 로고
    • Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition
    • Gudi S, Nolan JP, Frangos JA: Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition. Proc Natl Acad Sci U S A 95:2515-2519, 1998.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2515-2519
    • Gudi, S.1    Nolan, J.P.2    Frangos, J.A.3
  • 20
    • 0031000831 scopus 로고    scopus 로고
    • Measurement of nitric oxide in the rat cerebral cortex during hypercapnoea
    • Harada M, Fuse A, Tanaka Y: Measurement of nitric oxide in the rat cerebral cortex during hypercapnoea. Neuroreport 8:999-1002, 1997.
    • (1997) Neuroreport , vol.8 , pp. 999-1002
    • Harada, M.1    Fuse, A.2    Tanaka, Y.3
  • 21
    • 0028837365 scopus 로고
    • Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ
    • Helmlinger G, Berk BC, Nerem RM: Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ. Am J Physiol 269:C367-C375, 1995.
    • (1995) Am J Physiol , vol.269
    • Helmlinger, G.1    Berk, B.C.2    Nerem, R.M.3
  • 22
    • 0028940861 scopus 로고
    • Pressure enhances endothelin-1 release from cultured human endothelial cells
    • Hishikawa K, Nakaki T, Marumo T, Suzuki H, Kato R, Saruta T: Pressure enhances endothelin-1 release from cultured human endothelial cells. Hypertension 25:449-452, 1995.
    • (1995) Hypertension , vol.25 , pp. 449-452
    • Hishikawa, K.1    Nakaki, T.2    Marumo, T.3    Suzuki, H.4    Kato, R.5    Saruta, T.6
  • 23
    • 0027505606 scopus 로고
    • Pulsatile and steady flow induces c-Fos expression in human endothelial cells
    • Hsieh HJ, Li NQ, Frangos JA: Pulsatile and steady flow induces c-Fos expression in human endothelial cells. J Cell Physiol 154: 143-151, 1993.
    • (1993) J Cell Physiol , vol.154 , pp. 143-151
    • Hsieh, H.J.1    Li, N.Q.2    Frangos, J.A.3
  • 26
    • 0031883161 scopus 로고    scopus 로고
    • Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus
    • Ishii H, Koya D, King GL: Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus. J Mol Med 76:21-31, 1998.
    • (1998) J Mol Med , vol.76 , pp. 21-31
    • Ishii, H.1    Koya, D.2    King, G.L.3
  • 28
    • 0023896658 scopus 로고
    • Roles of fluid shear stress in physiological regulation of vascular structure and function
    • Kamiya A, Ando J, Shibata M, Masuda H: Roles of fluid shear stress in physiological regulation of vascular structure and function. Biorheology 25:271-278, 1988.
    • (1988) Biorheology , vol.25 , pp. 271-278
    • Kamiya, A.1    Ando, J.2    Shibata, M.3    Masuda, H.4
  • 29
    • 0028982830 scopus 로고
    • Nuclear factor-κB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress
    • Khachigian LM, Resnick N, Gimbrone MA Jr, Collins T: Nuclear factor-κB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J Clin Invest 96:1169-1175, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 1169-1175
    • Khachigian, L.M.1    Resnick, N.2    Gimbrone M.A., Jr.3    Collins, T.4
  • 30
    • 0028167846 scopus 로고
    • Inhibition of NF-κB by sodium salicylate and aspirin
    • Kopp E, Ghosh S: Inhibition of NF-κB by sodium salicylate and aspirin. Science 265:956-959, 1994.
    • (1994) Science , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 31
    • 0026344017 scopus 로고
    • Shear stress regulates smooth muscle proliferation and neointimal thickening in porous polytetrafluoroethylene grafts
    • Kraiss LW, Kirkman TR, Kohler TR, Zierler B, Clowes AW: Shear stress regulates smooth muscle proliferation and neointimal thickening in porous polytetrafluoroethylene grafts. Arterioscler Thromb 11:1844-1852, 1991.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1844-1852
    • Kraiss, L.W.1    Kirkman, T.R.2    Kohler, T.R.3    Zierler, B.4    Clowes, A.W.5
  • 32
    • 0021966255 scopus 로고
    • Pulsatile flow and atherosclerosis in the human carotid bifurcation: Positive correlation between plaque location and low oscillating shear stress
    • Ku DN, Giddens DP, Zarins CK, Glagov S: Pulsatile flow and atherosclerosis in the human carotid bifurcation: Positive correlation between plaque location and low oscillating shear stress. Arteriosclerosis 5:293-302, 1985.
    • (1985) Arteriosclerosis , vol.5 , pp. 293-302
    • Ku, D.N.1    Giddens, D.P.2    Zarins, C.K.3    Glagov, S.4
  • 33
    • 0022587290 scopus 로고
    • Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent
    • Langille BL, O'Donnell F: Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent. Science 231:405-407, 1986.
    • (1986) Science , vol.231 , pp. 405-407
    • Langille, B.L.1    O'Donnell, F.2
  • 35
    • 0028847727 scopus 로고
    • A cone-plate apparatus for the in vitro biochemical and molecular analysis of the effect of shear stress on adherent cells
    • Malek AM, Gibbons GH, Dzau VJ, Izumo S: A cone-plate apparatus for the in vitro biochemical and molecular analysis of the effect of shear stress on adherent cells. Methods Cell Sci 17:165-176, 1995.
    • (1995) Methods Cell Sci , vol.17 , pp. 165-176
    • Malek, A.M.1    Gibbons, G.H.2    Dzau, V.J.3    Izumo, S.4
  • 36
    • 0033534742 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase mRNA by shear stress requires intracellular calcium and G-protein signals and is modulated by PI-3-kinase
    • Malek AM, Jiang L, Lee I, Sessa WC, Izumo S, Alper SL: Induction of nitric oxide synthase mRNA by shear stress requires intracellular calcium and G-protein signals and is modulated by PI-3-kinase. Biochem Biophys Res Commun 254:231-242, 1999.
    • (1999) Biochem Biophys Res Commun , vol.254 , pp. 231-242
    • Malek, A.M.1    Jiang, L.2    Lee, I.3    Sessa, W.C.4    Izumo, S.5    Alper, S.L.6
  • 37
    • 0027938194 scopus 로고
    • Kourembanas S: Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
    • [published errata appear in Am J Physiol 268(2 Pt 2): section H following table of contents and 268(6 Pt 3):section H following table of contents, 1995]
    • McQuillan LP, Leung GK, Marsden PA, Kostyk SK, Kourembanas S: Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms [published errata appear in Am J Physiol 268(2 Pt 2): section H following table of contents and 268(6 Pt 3):section H following table of contents, 1995]. Am J Physiol 267:H1921-H1927, 1994.
    • (1994) Am J Physiol , vol.267
    • McQuillan, L.P.1    Leung, G.K.2    Marsden, P.A.3    Kostyk, S.K.4
  • 40
    • 0028918698 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with essential hypertension: Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway
    • Panza JA, Garcia CE, Kilcoyne CM, Quyyumi AA, Cannon RO III: Impaired endothelium-dependent vasodilation in patients with essential hypertension: Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway. Circulation 91:1732-1738, 1995.
    • (1995) Circulation , vol.91 , pp. 1732-1738
    • Panza, J.A.1    Garcia, C.E.2    Kilcoyne, C.M.3    Quyyumi, A.A.4    Cannon R.O. III5
  • 41
    • 0029948575 scopus 로고    scopus 로고
    • Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells
    • Phelan MW, Faller DV: Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells. J Cell Physiol 167:469-476, 1996.
    • (1996) J Cell Physiol , vol.167 , pp. 469-476
    • Phelan, M.W.1    Faller, D.V.2
  • 42
    • 0028878919 scopus 로고
    • Constitutive nos expression in cultured endothelial cells is elevated by fluid shear stress
    • Ranjan V, Xiao Z, Diamond SL: Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress. Am J Physiol 269:H550-H555, 1995.
    • (1995) Am J Physiol , vol.269
    • Ranjan, V.1    Xiao, Z.2    Diamond, S.L.3
  • 44
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R: The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 362:801-809, 1993.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 45
    • 0028294885 scopus 로고
    • Premature carotid atherosclerosis: Does it occur in both familial hypercholesterolemia and homocystinuria? ultrasound assessment of arterial intima-media thickness and blood flow velocity
    • Rubba P, Mercuri M, Faccenda F, Iannuzzi A, Irace C, Strisciuglio P, Gnasso A, Tang R, Andria G, Bond MG: Premature carotid atherosclerosis: Does it occur in both familial hypercholesterolemia and homocystinuria? Ultrasound assessment of arterial intima-media thickness and blood flow velocity. Stroke 25:943-950, 1994.
    • (1994) Stroke , vol.25 , pp. 943-950
    • Rubba, P.1    Mercuri, M.2    Faccenda, F.3    Iannuzzi, A.4    Irace, C.5    Strisciuglio, P.6    Gnasso, A.7    Tang, R.8    Andria, G.9    Bond, M.G.10
  • 46
    • 0032520153 scopus 로고    scopus 로고
    • Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
    • Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC: Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest 101:731-736, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 731-736
    • Rudic, R.D.1    Shesely, E.G.2    Maeda, N.3    Smithies, O.4    Segal, S.S.5    Sessa, W.C.6
  • 47
    • 0031018333 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans
    • Tawakol A, Omland T, Gerhard M, Wu JT, Creager MA: Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation 95:1119-1121, 1997.
    • (1997) Circulation , vol.95 , pp. 1119-1121
    • Tawakol, A.1    Omland, T.2    Gerhard, M.3    Wu, J.T.4    Creager, M.A.5
  • 48
    • 0029196096 scopus 로고
    • Oscillatory shear stress and hydrostatic pressure modulate cell-matrix attachment proteins in cultured endothelial cells
    • Thoumine O, Nerem RM, Girard PR: Oscillatory shear stress and hydrostatic pressure modulate cell-matrix attachment proteins in cultured endothelial cells. In Vitro Cell Dev Biol Anim 31:45-54, 1995.
    • (1995) In Vitro Cell Dev Biol Anim , vol.31 , pp. 45-54
    • Thoumine, O.1    Nerem, R.M.2    Girard, P.R.3
  • 49
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
    • Traub O, Berk BC: Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 18:677-685, 1998.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 54
    • 0029787425 scopus 로고    scopus 로고
    • + exchange is necessary for RhoA-induced stress fiber formation
    • + exchange is necessary for RhoA-induced stress fiber formation. J Biol Chem 271:22281-22284, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 22281-22284
    • Vexler, Z.S.1    Symons, M.2    Barber, D.L.3
  • 56
    • 0028951498 scopus 로고
    • Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells
    • Weber C, Erl W, Pietsch A, Weber PC: Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation 91:1914-1917, 1995.
    • (1995) Circulation , vol.91 , pp. 1914-1917
    • Weber, C.1    Erl, W.2    Pietsch, A.3    Weber, P.C.4
  • 57
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch GN, Loscalzo J: Homocysteine and atherothrombosis. N Engl J Med 338:1042-1050, 1998.
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.N.1    Loscalzo, J.2
  • 58
    • 0344073985 scopus 로고    scopus 로고
    • Atherosclerosis and the two faces of endothelial nitric oxide synthase
    • Wever RM, Luscher TF, Cosentino F, Rabelink TJ: Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation 97:108-112, 1998.
    • (1998) Circulation , vol.97 , pp. 108-112
    • Wever, R.M.1    Luscher, T.F.2    Cosentino, F.3    Rabelink, T.J.4
  • 59
    • 0030007350 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus
    • Williams SB, Cusco JA, Roddy MA, Johnstone MT, Creager MA: Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus, J Am Coll Cardiol 27:567-574, 1996.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 567-574
    • Williams, S.B.1    Cusco, J.A.2    Roddy, M.A.3    Johnstone, M.T.4    Creager, M.A.5
  • 61
    • 0030925802 scopus 로고    scopus 로고
    • Shear stress induction of the endothelial nitric oxide synthase gene is calcium-dependent but not calcium-activated
    • Xiao Z, Zhang Z, Diamond SL: Shear stress induction of the endothelial nitric oxide synthase gene is calcium-dependent but not calcium-activated. J Cell Physiol 171:205-211, 1997.
    • (1997) J Cell Physiol , vol.171 , pp. 205-211
    • Xiao, Z.1    Zhang, Z.2    Diamond, S.L.3
  • 63
    • 0026478845 scopus 로고
    • Flow-dependent cytosolic acidification of vascular endothelial cells
    • Ziegelstein RC, Cheng L, Capogrossi MC: Flow-dependent cytosolic acidification of vascular endothelial cells. Science 258: 656-659, 1992.
    • (1992) Science , vol.258 , pp. 656-659
    • Ziegelstein, R.C.1    Cheng, L.2    Capogrossi, M.C.3
  • 64
    • 0031806789 scopus 로고    scopus 로고
    • Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells
    • Ziegler T, Bouzourene K, Harrison VJ, Brunner HR, Hayoz D: Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells. Arterioscler Thromb Vasc Biol 18:686-692, 1998.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 686-692
    • Ziegler, T.1    Bouzourene, K.2    Harrison, V.J.3    Brunner, H.R.4    Hayoz, D.5


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