Association between the RAGE G82S polymorphism and Alzheimer's disease

Journal of Neural Transmission

Volumn 117, Issue 1, 2010, Pages 97-104

  Li, Keshen ^a,b   Dai, Dawei ^c   Zhao, Bin ^a   Yao, Lifen ^c   Yao, Songpo ^c,d   Wang, Binyou ^c   Yang, Ze ^e  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b HARBIN ENGINEERING UNIVERSITY   (China)

^c HARBIN MEDICAL UNIVERSITY   (China)

^d JIAMUSI UNIVERSITY   (China)

^e BEIJING HOSPITAL   (China)

Author keywords

Alzheimer's disease; Association study; Polymorphism; Receptor for advanced glycation end products; Risk factor

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; DNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 3;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CHINESE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PREVALENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

AGE OF ONSET; AGED; ALZHEIMER DISEASE; ANTIGENS, NEOPLASM; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COGNITION DISORDERS; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION, MISSENSE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 76949092906     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-009-0334-6     Document Type: Article

References (44)

1. O Arancio HP Zhang X Chen C Lin F Trinchese D Puzzo S Liu A Hegde SF Yan A Stern JS Luddy LF Lue DG Walker A Roher M Buttini L Mucke W Li AM Schmidt M Kindy PA Hyslop DM Stern SS Du Yan 2004 RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice EMBO J 23 4096 4105 10.1038/sj.emboj.7600415 1:CAS:528:DC%2BD2cXotlCrs7Y%3D 15457210 (Pubitemid 39472430)
2. M Cacquevel N Lebeurrier S Chéenne D Vivien 2004 Cytokines in neuroinflammation and Alzheimer's disease Curr Drug Targets 5 529 534 10.2174/1389450043345308 1:CAS:528:DC%2BD2cXlslWjtro%3D 15270199 (Pubitemid 39004427)
3. M Catalano A Cortelazzo R Santi L Contino M Demicheli Y Yilmaz M Zorzetto I Campo N Lanati E Emanuele 2008 The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (receptor for advanced glycation endproducts) and the presence of peripheral arterial disease Clin Biochem 41 981 985 10.1016/j.clinbiochem.2008. 05.007 1:CAS:528:DC%2BD1cXoslemt7g%3D 18538667
4. MO Chaney WB Stine TA Kokjohn YM Kuo C Esh A Rahman DC Luehrs AM Schmidt D Stern SD Yan AE Roher 2005 RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling Biochim Biophys Acta 1741 199 205 1:CAS:528:DC%2BD2MXlt1Witr4%3D 15882940
5. X Chen DG Walker AM Schmidt O Arancio LF Lue SD Yan 2007 RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease Curr Mol Med 7 735 742 10.2174/156652407783220741 1:CAS:528: DC%2BD1cXhvF2hurk%3D 18331231
6. A Convit OT Wolf C Tarshish MJ de Leon 2003 Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly Proc Natl Acad Sci USA 100 2019 2022 10.1073/pnas.0336073100 1:CAS:528:DC%2BD3sXhsFGrsb8%3D 12571363 (Pubitemid 36254566)
7. RS Doody P Massman JK Dunn 2001 A method for estimating progression rates in Alzheimer disease Arch Neurol 58 449 454 10.1001/archneur.58.3.449 1:STN:280:DC%2BD3M7pvVCiug%3D%3D 11255449
8. E Emanuele A D'Angelo C Tomaino G Binetti R Ghidoni P Politi L Bernardi R Maletta AC Bruni D Geroldi 2005 Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia Arch Neurol 62 1734 1736 10.1001/archneur.62.11.1734 16286548 (Pubitemid 41626671)
9. Ertekin-Taner N (2007) Genetics of Alzheimer's disease: a centennial review. Neurol Clin 25:611-667, v
10. R Ghidoni L Benussi M Glionna M Franzoni D Geroldi E Emanuele G Binetti 2008 Decreased plasma levels of soluble receptor for advanced glycation end products in mild cognitive impairment J Neural Transm 115 1047 1050 10.1007/s00702-008-0069-9 1:CAS:528:DC%2BD1cXotV2mtLo%3D 18506386
11. RCP Go JS Collins B Watson Jr CJ Vanichanan RT Acton D Blacker MS Albert R Tanzi MG McInnis SS Bassett D Campbell RT Perry 1998 Evidence for linkage to 6p21.3 in Alzheimer disease families containing APOE E4/E4 genotypes Am J Hum Genet 634 A291
12. H Gu L Yang Q Sun B Zhou N Tang R Cong Y Zeng B Wang 2008 Gly82Ser polymorphism of the receptor for advanced glycation end products is associated with an increased risk of gastric cancer in a Chinese population Clin Cancer Res 14 3627 3632 10.1158/1078-0432.CCR-07-4808 1:CAS:528:DC%2BD1cXmslygt7c%3D 18519797
13. L Ho W Qin PN Pompl Z Xiang J Wang Z Zhao Y Peng G Cambareri A Rocher CV Mobbs PR Hof GM Pasinetti 2004 Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease FASEB J 18 902 904 1:CAS:528:DC%2BD2cXjvVCltr8%3D 15033922
14. MA Hofmann S Drury BI Hudson MR Gleason W Qu Y Lu E Lalla S Chitnis J Monteiro MH Stickland LG Bucciarelli B Moser G Moxley S Itescu PJ Grant PK Gregersen DM Stern AM Schmidt 2002 RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response Genes Immun 3 123 135 10.1038/sj.gene. 6363861 1:CAS:528:DC%2BD38Xktlyrsrg%3D 12070776 (Pubitemid 38961122)
15. BI Hudson MH Stickland PJ Grant 1998 Identification of polymorphisms in the receptor for advanced glycation end products (RAGE) gene: prevalence in type 2 diabetes and ethnic groups Diabetes 47 1155 1157 10.2337/diabetes.47.7.1155 1:CAS:528:DyaK1cXkt1alsr8%3D 9648842 (Pubitemid 28294561)
16. BI Hudson MH Stickland TS Futers P Grant 2001 Effects of novel polymorphisms in the RAGE gene on transcriptional regulation and their association with diabetic retinopathy Diabetes 50 1505 1511 10.2337/diabetes.50. 6.1505 1:CAS:528:DC%2BD3MXkvFSgt7w%3D 11375354
17. Y Jang JY Kim SM Kang JS Kim JS Chae OY Kim SJ Koh HC Lee CW Ahn YD Song JH Lee 2007 Association of the Gly82Ser polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating levels of soluble RAGE and inflammatory markers in nondiabetic and nonobese Koreans Metabolism 56 199 205 10.1016/j.metabol.2006.09.013 1:CAS:528:DC%2BD2sXlslSgtQ%3D%3D 17224333 (Pubitemid 46074066)
18. FM LaFerla S Oddo 2005 Alzheimer's disease: Abeta, tau and synaptic dysfunction Trends Mol Med 11 170 176 10.1016/j.molmed.2005.02.009 1:CAS:528:DC%2BD2MXjtVylsb8%3D 15823755
19. JC Lambert D Mann J Harris L Araria-Goumidi MC Chartier-Harlin D Cottel T Iwatsubo P Amouyel C Lendon 2004 Association study of Notch 4 polymorphisms with Alzheimer's disease J Neurol Neurosurg Psychiatry 75 377 381 10.1136/jnnp.2003.017368 14966150 (Pubitemid 38338765)
20. LF Lue DG Walker L Brachova TG Beach J Rogers AM Schmidt DM Stern SD Yan 2001 Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism Exp Neurol 171 29 45 10.1006/exnr.2001.7732 1:CAS:528:DC%2BD3MXmtFyqtrc%3D 11520119 (Pubitemid 32848443)
21. LF Lue SD Yan DM Stern DG Walker 2005 Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease Curr Drug Targets CNS Neurol Disord 4 249 266 10.2174/1568007054038210 1:CAS:528:DC%2BD2MXkvF2ls7o%3D 15975028 (Pubitemid 40754161)
22. SL Ma NL Tang CW Tam VW Lui EW Suen HF Chiu LC Lam 2008 Association between HLA-A alleles and Alzheimer's disease in a southern Chinese community Dement Geriatr Cogn Disord 26 391 397 10.1159/000164275 1:CAS:528: DC%2BD1cXhtl2qtbnJ 18936542
23. T Matsui S Yamagishi S Ueda K Nakamura T Imaizumi M Takeuchi H Inoue 2007 Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-gamma activation J Int Med Res 35 482 489 1:CAS:528:DC%2BD2sXhtVers7fP 17697525
24. G McKhann D Drachman M Folstein R Katzman D Price EM Stadlan 1984 Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease Neurology 34 939 944 1:STN:280:DyaL2c3ks1altQ%3D%3D 6610841
25. M Neeper AM Schmidt J Brett SD Yan F Wang YC Pan K Elliston D Stern A Shaw 1992 Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins J Biol Chem 267 14998 15004 1:CAS:528:DyaK3sXktVGnt7w%3D 1378843
26. I Nozaki T Watanabe M Kawaguchi H Akatsu K Tsuneyama Y Yamamoto K Ohe H Yonekura M Yamada H Yamamoto 2007 Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains Arch Histol Cytol 70 279 290 10.1679/aohc.70.279 1:CAS:528:DC%2BD1cXmtlSkurk%3D 18431028 (Pubitemid 351594919)
27. IG Onyango JB Tuttle JP Bennett Jr 2005 Altered intracellular signaling and reduced viability of Alzheimer's disease neuronal cybrids is reproduced by beta-amyloid peptide acting through receptor for advanced glycation end products (RAGE) Mol Cell Neurosci 29 333 343 10.1016/j.mcn.2005.02.012 1:CAS:528:DC%2BD2MXks1Wlu70%3D 15911356 (Pubitemid 40725622)
28. N Origlia M Righi S Capsoni A Cattaneo F Fang DM Stern JX Chen AM Schmidt O Arancio SD Yan L Domenici 2008 Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction J Neurosci 28 3521 3530 10.1523/JNEUROSCI.0204-08.2008 1:CAS:528:DC%2BD1cXkt1ahtLo%3D 18367618
29. IH Park SI Yeon JH Youn JE Choi N Sasaki IH Choi JS Shin 2004 Expression of a novel secreted splice variant of the receptor for advanced glycation end products (RAGE) in human brain astrocytes and peripheral blood mononuclear cells Mol Immunol 40 1203 1211 10.1016/j.molimm.2003.11.027 1:CAS:528: DC%2BD2cXht1agurg%3D 15104125 (Pubitemid 38210272)
30. G Prevost I Fajardy P Fontaine PM Danze C Besmond 1999 Human RAGE GLY82SER dimorphism and HLA class II DRB1-DQA1-DQB1 haplotypes in type 1 diabetes Eur J Immunogenet 26 343 348 10.1046/j.1365-2370.1999.00168.x 1:CAS:528:DyaK1MXnvVWqtb8%3D 10553500 (Pubitemid 29479000)
31. R Pullerits M Bokarewa L Dahlberg A Tarkowski 2005 Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control Arthritis Res Ther 7 R817 R824 10.1186/ar1749 1:CAS:528:DC%2BD2MXkt1Cjsb4%3D 15987483
32. C Schlueter S Hauke AM Flohr P Rogalla J Bullerdiek 2003 Tissue-specific expression patterns of the RAGE receptor and its soluble forms-a result of regulated alternative splicing? Biochim Biophys Acta 1630 1 6 1:CAS:528:DC%2BD3sXot1Oksbw%3D 14580673
33. AM Schmidt SD Yan SF Yan DM Stern 2000 The biology of the receptor for advanced glycation end products and its ligands Biochim Biophys Acta 1498 99 111 10.1016/S0167-4889(00)00087-2 1:CAS:528:DC%2BD3cXosFCjsrw%3D 11108954
34. AM Schmidt SD Yan SF Yan DM Stern 2001 The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses J Clin Invest 108 949 955 1:CAS:528:DC%2BD3MXnt1Cku7k%3D 11581294
35. AM Stranahan ED Norman K Lee RG Cutler RS Telljohann JM Egan MP Mattson 2008 Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats Hippocampus 18 1085 1088 10.1002/hipo.20470 18651634
36. E Sturchler A Galichet M Weibel E Leclerc CW Heizmann 2008 Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity J Neurosci 28 5149 5158 10.1523/JNEUROSCI.4878-07.2008 1:CAS:528:DC%2BD1cXmt1SltrY%3D 18480271
37. K Sugaya T Fukagawa K Matsumoto K Mita E Takahashi A Ando H Inoko T Ikemura 1994 Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3 Genomics 23 408 419 10.1006/geno.1994.1517 1:CAS:528: DyaK2MXhtFOhsb8%3D 7835890 (Pubitemid 24308262)
38. M Takeuchi S Kikuchi N Sasaki T Suzuki T Watai M Iwaki R Bucala S Yamagishi 2004 Involvement of advanced glycation end-products (AGEs) in Alzheimer's disease Curr Alzheimer Res 1 39 46 10.2174/1567205043480582 1:CAS:528:DC%2BD2cXjvF2jtLg%3D 15975084
39. N Tanaka H Yonekura S Yamagishi H Fujimori Y Yamamoto H Yamamoto 2000 The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells J Biol Chem 275 25781 25790 10.1074/jbc.M001235200 1:CAS:528:DC%2BD3cXmtVehtL4%3D 10829018 (Pubitemid 30687083)
40. GS Watson S Craft 2006 Insulin resistance, inflammation, and cognition in Alzheimer's disease: lessons for multiple sclerosis J Neurol Sci 245 21 33 10.1016/j.jns.2005.08.017 1:CAS:528:DC%2BD28Xlt1CltL0%3D 16631207
41. SD Yan X Chen J Fu M Chen H Zhu A Roher T Slattery L Zhao M Nagashima J Morser A Migheli P Nawroth D Stern AM Schmidt 1996 RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease Nature 382 685 691 10.1038/382685a0 1:CAS:528:DyaK28Xlt1yltr0%3D 8751438 (Pubitemid 26282167)
42. SD Yan H Zhu J Fu SF Yan A Roher WW Tourtellotte T Rajavashisth X Chen GC Godman D Stern AM Schmidt 1997 Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease Proc Natl Acad Sci USA 94 5296 5301 10.1073/pnas.94.10.5296 1:CAS:528:DyaK2sXjtleltrY%3D 9144231 (Pubitemid 27214777)
43. T Yoshida S Yamagishi K Nakamura T Matsui T Imaizumi M Takeuchi H Koga T Ueno M Sata 2006 Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation Diabetologia 49 3094 3099 10.1007/s00125-006-0437-7 1:CAS:528:DC%2BD28XhtFylt7nL 17004092 (Pubitemid 44730314)
44. K Yoshioka T Yoshida Y Takakura T Umekawa A Kogure H Toda T Yoshikawa 2005 Association study of G1704T and G82S polymorphisms of RAGE gene for microalbuminuria in Japanese type 2 diabetic patients Metabolism 54 488 491 10.1016/j.metabol.2004.11.001 1:CAS:528:DC%2BD2MXis1Gqs7w%3D 15798956 (Pubitemid 40410450)