Association of the Gly82Ser polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating levels of soluble RAGE and inflammatory markers in nondiabetic and nonobese Koreans

Metabolism: Clinical and Experimental

Volumn 56, Issue 2, 2007, Pages 199-205

  Jang, Yangsoo ^a,b   Kim, Ji Young ^b,c   Kang, Seok Min ^a   Kim, Jung Sun ^a   Chae, Jey Sook ^b   Kim, Oh Yoen ^b   Koh, Soo Jeong ^b   Lee, Hyun Chul ^a   Ahn, Chul Woo ^a   Song, Young Duk ^d   Lee, Jong Ho ^b  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c DNA Link Inc   (South Korea)

^d National Health Insurance Corporation   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALCOHOL; BIOLOGICAL MARKER; C REACTIVE PROTEIN; GLUCOSE; INSULIN; LIPID; PROSTAGLANDIN F2 ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; ANTHROPOMETRY; ARTICLE; BLOOD LEVEL; BODY MASS; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE MARKER; DRINKING BEHAVIOR; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HOMOZYGOSITY; HUMAN; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; KOREA; LIPID BLOOD LEVEL; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEPTOR GENE; RISK FACTOR; SENSITIVITY ANALYSIS; SEX; STATISTICAL SIGNIFICANCE; URINARY EXCRETION;

5' UNTRANSLATED REGIONS; ADIPONECTIN; ADULT; AGED; ANTHROPOMETRY; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; C-REACTIVE PROTEIN; DINOPROST; EXONS; FEMALE; GENOTYPE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; INFLAMMATION; INSULIN; KOREA; LIPID PEROXIDES; LIPIDS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, IMMUNOLOGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33846044183     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2006.09.013     Document Type: Article

References (32)

1. Hudson B.I., and Schmidt A.M. RAGE: a novel target for drug intervention in diabetic vascular disease. Pharm Res 21 (2004) 1079-1086
2. Yan S.F., Ramasamy R., Naka Y., and Schmidt A.M. Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond. Circ Res 93 (2003) 1159-1169
3. Falcone C., Campo I., Emanuele E., Buzzi M.P., Geroldi D., Belvito C., et al. -374T/A polymorphism of the RAGE gene promoter in relation to severity of coronary atherosclerosis. Clin Chim Acta 354 (2005) 111-116
4. Kanauchi M., Tsujimoto N., and Hashimoto T. Advanced glycation end products in nondiabetic patients with coronary artery disease. Diabetes Care 24 (2001) 1620-1623
5. Chavakis T., Bierhaus A., and Nawroth P.P. RAGE (receptor for advanced glycation end products): a central player in the inflammatory response. Microbes Infect 6 (2004) 1219-1225
6. Stern D.M., Yan S.D., Yan S.F., and Schmidt A.M. Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes. Ageing Res 1 (2002) 1-15
7. Hudson B.I., Bucciarelli L.G., Wendt T., Sakaguchi T., Lalla E., Qu W., et al. Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders. Arch Biochem Biophys 419 (2003) 80-88
8. Falcone C., Emanuele E., D'Angelo A., Buzzi M.P., Belvito C., Cuccia M., et al. Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men. Arterioscler Thromb Vasc Biol 25 (2005) 1032-1037
9. Yoshioka K., Yoshida T., Takakura Y., Umekawa T., Kogure A., Toda H., et al. Association study of G1704T and G82S polymorphisms of RAGE gene for microalbuminuria in Japanese type 2 diabetic patients. Metabolism 54 (2005) 488-491
10. Malherbe P., Richards J.G., Gaillard H., Thompson A., Diener C., Schuler A., et al. cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein. Brain Res Mol Brain Res 71 (1999) 159-170
11. Yonekura H., Yamamoto Y., Sakurai S., Petrova R.G., Abedin M.J., Li H., et al. Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. Biochem J 370 (2003) 1097-1099
12. Park I.H., Yeon S.I., Youn J.H., Choi J.E., Sasaki N., Choi I.H., et al. Expression of a novel secreted splice variant of the receptor for advanced glycation end products (RAGE) in human brain astrocytes and peripheral blood mononuclear cells. Mol Immunol 40 (2004) 1203-1211
13. Yonekura H., Yamamoto Y., Sakurai S., Petrova R.G., Abedin M.J., Li H., et al. Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. Biochem J 370 (2003) 1097-1109
14. Kislinger T., Fu C., Huber B., Qu W., Taguchi A., Du Yan S., et al. N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem 1274 (1999) 31740-31749
15. Hanford L.E., Enghild J.J., Valnickova Z., Petersen S.V., Schaefer L.M., Schaefer T.M., et al. Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE). J Biol Chem 279 (2004) 50019-50024
16. Pullerits R., Bokarewa M., Dahlberg L., and Tarkowski A. Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control. Arthritis Res Ther 7 (2005) R817-R824
17. Hofmann M.A., Drury S., Hudson B.I., Gleason M.R., Qu W., Lu Y., et al. RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. Genes Immun 3 (2002) 123-135
18. Hofmann M.A., Yang O., Harja E., Kedia P., Gregersen P.K., Cupples L.A., et al. The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study. Atherosclerosis 182 (2005) 301-305
19. Moshides J.S. Kinetic enzymatic method for automated determination of HDL cholesterol in plasma. J Clin Chem Clin Biochem 25 (1987) 583-587
20. Friedewald W.T., Levy R.T., and Frederickson D.S. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the ultracentrifuge. Clin Chem 18 (1972) 449-502
21. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
22. Horiuchi S., Araki N., and Morino Y. Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. J Biol Chem 266 (1991) 7329-7332
23. Taussky H.H. A procedure increasing the specificity of the Jaffe reaction for the determination of creatinine and creatinine in urine and plasma. Clin Chim Acta 1 (1956) 210-224
24. Kankova K., Zahejsky J., Marova I., Muzik J., Kuhrova V., Blazkova M., et al. Polymorphisms in the RAGE gene influence susceptibility to diabetes-associated microvascular dermatoses in NIDDM. J Diabetes Complications 15 (2001) 185-192
25. Kankova K., Vasku A., Hajek D., Zahejsky J., and Vasku V. Association of G82S polymorphism in the RAGE gene with skin complications in type 2 diabetes. Diabetes Care 22 (1999) 1745
26. Yonekura H., Yamamoto Y., Sakurai S., Petrova R.G., Abedin M.J., Li H., et al. Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. Biochem J 370 (2003) 1097-1099
27. Hudson B.I., Harja E., Moser B., and Schmidt A.M. Soluble levels of receptor for advanced glycation endproducts (sRAGE) and coronary artery disease the next C-reactive protein?. Arterioscler Thromb Vasc Biol 25 (2005) 879-882
28. Rifai N., and Ridker P.M. High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease. Clin Chem 47 (2001) 3403-3411
29. Hofmann M.A., Drury S., Hudson B.I., Gleason M.R., Qu W., Lu Y., et al. RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. Genes Immun 3 (2003) 123-135
30. Baynes J.W., and Thorpe S.R. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 48 (1999) 1-9
31. Paolisso G., Tagliamonte M.R., Rizzo M.R., and Giugliano D. Advancing age and insulin resistance. Eur J Clin Invest 29 (1999) 758-769
32. Ridker P.M., Buring J.E., Cook N.R., and Rifai N. C-Reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation 107 (2003) 391-397