Association between HLA-A alleles and Alzheimer's disease in a Southern Chinese community

Dementia and Geriatric Cognitive Disorders

Volumn 26, Issue 5, 2008, Pages 391-397

  Ma, Suk Ling ^a   Tang, Nelson Leung Sang ^a   Tam, Cindy Woon Chi ^b   Lui, Victor Wing Cheong ^b   Suen, Eddie Wai Chui ^a   Chiu, Helen Fung Kum ^b   Lam, Linda Chiu Wa ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Alzheimer's disease; Chinese, Alzheimer's disease; Genetics, Alzheimer's disease; HLA

Indexed keywords

APOLIPOPROTEIN E; HLA A ANTIGEN; HLA A2 ANTIGEN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CHINESE; CHROMOSOME 6P; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PATHOGENESIS; PRIORITY JOURNAL;

AGE OF ONSET; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; CASE-CONTROL STUDIES; CHINA; DNA; DOUBLE-BLIND METHOD; EXONS; FEMALE; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; HISTOCOMPATIBILITY TESTING; HLA-A ANTIGENS; HUMANS; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SURVIVAL ANALYSIS;

EID: 53949125938     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000164275     Document Type: Article

References (36)

1. Akiyama H, Barger S, Barnum S, et al: Inflammation and Alzheimer's disease. Neurobiol Aging 2000;21:383-421.
2. Ahluwalia N, Vellas B: Immunologic and inflammatory mediators and cognitive decline in Alzheimer's disease. Immunol Allergy Clin North Am 2003;23:103-115.
3. Candore G, Balistreri CR, Grimaldi MP, et al: Polymorphisms of pro-inflammatory genes and Alzheimer's disease risk: a pharmacogenomic approach. Mech Ageing Dev 2007;128: 67-75.
4. Listi F, Candore G, Balistreri CR, et al: Association between the HLA-A2 allele and Alzheimer disease. Rejuvenation Res 2006;9:99-101.
5. Ma SL, Tang NL, Lam LC, et al: Association between tumor necrosis factor-alpha promoter polymorphism and Alzheimer's disease. Neurology 2004;62:307-309.
6. Ma SL, Tang NL, Lam LC, et al: The association between promoter polymorphism of the interleukin-10 gene and Alzheimer's disease. Neurobiol Aging 2005;26:1005-1010.
7. Huang SM, Wu TJ, Lee TD, et al: The association of HLA-A, -B, and -DRB1 genotypes with Graves' disease in Taiwanese people. Tissue Antigens 2003;61:154-158.
8. Lu CC, Chen JC, Jin YT, et al: Genetic susceptibility to nasopharyngeal carcinoma within the HLA-A locus in Taiwanese. Int J Cancer 2003;103:745-751.
9. GAMES: A meta-analysis of whole genome linkage screens in multiple sclerosis. J Neuroimmunol 2003;143:39-46.
10. Small GW, Matsuyama SS: HLA-A2 as a possible marker for early-onset Alzheimer disease in men. Neurobiol Aging 1986;7:211-214.
11. Neill D, Curran MD, Middleton D, et al: Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1 *03. Neurosci Lett 1999;275:137-140.
12. Payami H, Kaye J, Becker W, et al: HLA-A2, or a closely linked gene, confers susceptibility to early-onset sporadic Alzheimer's disease in men. Neurology 1991;41:1544-1548.
13. Harris JM, Cumming AM, Craddock N, et al: Human leucocyte antigen-A2 increases risk of Alzheimer's disease but does not affect age of onset in a Scottish population. Neurosci Lett 2000;294:37-40.
14. Ballerini C, Nacmias B, Rombola G, et al: HLA A2 allele is associated with age at onset of Alzheimer's disease. Ann Neurol 1999;45:397-400.
15. Small GW, Ebeling SC, Matsuyama SS, et al: Variable association of HLA-A2 in men with early-onset Alzheimer disease. Neurobiol Aging 1991;12:375-377.
16. Araria-Goumidi L, Lambert JC, Cottel D, et al: No association of the HLA-A2 allele with Alzheimer's disease. Neurosci Lett 2002;335:75-78.
17. Middleton D, Mawhinney H, Curran MD, et al: Frequency of HLA-A and -B alleles in early-and late-onset Alzheimer's disease. Neurosci Lett 1999;262:140-142.
18. Guttridge MG, Street J, Thomas M, Darke C: Identification of HLA-A *0224: implications for PCR-SSP HLA typing. Tissue Antigens 1999;53:190-193.
19. Zareparsi S, James DM, Kaye JA, et al: HLAA2 homozygosity but not heterozygosity is associated with Alzheimer disease. Neurology 2002;58:973-975.
20. Chiu HF, Lam LC, Chi I, Leung T, et al: Prevalence of dementia in Chinese elderly in Hong Kong. Neurology 1998;50:1002-1009.
21. Chan AS, Choi MK, Salmon DP: The effects of age, education, and gender on the Mattis Dementia Rating Scale performance of elderly Chinese and American individuals. J Gerontol B Psychol Sci Soc Sci 2001;56:356-363.
22. Chu LW, Chiu KC, Hui SL, et al: The reliability and validity of the Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) among the elderly Chinese in Hong Kong. Ann Acad Med Singapore 2000;29:474-485.
23. Tsukamoto K, Watanabe T, Matsushima T, et al: Determination by PCR-RFLP of Apo E genotype in a Japanese population. J Lab Clin Med 1993;121:598-602.
24. Tang MX, Jacobs D, Stern Y, et al: Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 1996;348:429-432.
25. Cao K, Hollenbach J, Shi X, et al: Analysis of the frequencies of HLA-A, -B, and -C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum Immunol 2001;62:1009-1030.
26. Schreuder GM, Hurley CK, Marsh SG, et al: HLA dictionary 2004: summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR, and -DQ antigens. Hum Immunol 2005;66:170-210.
27. Chang YW, Hawkins BR: HLA class I and class II frequencies of a Hong Kong Chinese population based on bone marrow donor registry data. Hum Immunol 1997;56:125-135.
28. Payami H, Schellenberg GD, Zareparsi S, et al: Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease. Neurology 1997;49:512-518.
29. Small GW, Scott WK, Komo S, et al: No association between the HLA-A2 allele and Alzheimer disease. Neurogenetics 1999;2:177-182.
30. Combarros O, Escribano J, Sanchez-Velasco P, et al: Association of the HLA-A2 allele with an earlier age of onset of Alzheimer's disease. Acta Neurol Scand 1998;98:140-141.
31. Nakanishi K, Kobayashi T, Murase T, et al: Association of HLA-A24 with complete beta-cell destruction in IDDM. Diabetes 1993;42:1086-1093.
32. Wright P, Nimgaonkar VL, Donaldson PT, Murray RM: Schizophrenia and HLA: a review. Schizophr Res 2001;47:1-12.
33. Collins JS, Perry RT, Watson B Jr, et al: Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative. Am J Med Genet 2000;96:823-830.
34. Du Y, Dodel RC, Eastwood BJ, Bales KR, et al: Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology 2000;55:480-483.
35. Shibata N, Ohnuma T, Takahashi T, et al: Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases. Am J Med Genet 2002;114:436-439.
36. Griffin WS, Mrak RE: Interleukin-1 in the genesis and progression of and risk for development of neuronal degeneration in Alzheimer's disease. J Leukoc Biol 2002;72:233-238.