-
1
-
-
3042783575
-
A critical review of the bioavailability of glucosinolates and related compounds
-
Holst, B., Williamson, G., A critical review of the bioavailability of glucosinolates and related compounds, Nat. Prod. Rep. 2004, 21, 425-447.
-
(2004)
Nat. Prod. Rep.
, vol.21
, pp. 425-447
-
-
Holst, B.1
Williamson, G.2
-
2
-
-
38949204895
-
Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in the rat
-
Hanlon, C., Coldham, C., Gielbert, A., Kuhnert, N., et al., Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in the rat, Br. J. Nutr. 2008, 99, 559-564.
-
(2008)
Br. J. Nutr.
, vol.99
, pp. 559-564
-
-
Hanlon, C.1
Coldham, C.2
Gielbert, A.3
Kuhnert, N.4
-
3
-
-
0032948428
-
Conversion of isothiocyanates in humans after ingestion of cooked watercress, Cancer Epidemiol
-
Getahun, S. M., Chung, F.-L., Conversion of isothiocyanates in humans after ingestion of cooked watercress, Cancer Epidemiol. Biomarkers Prev. 1999, 8, 447-451.
-
(1999)
Biomarkers Prev.
, vol.8
, pp. 447-451
-
-
Getahun, S.M.1
Chung, F.-L.2
-
4
-
-
26444561456
-
Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity
-
Yoxall, V., Kentish, P., Coldham, N., Kuhnert, N., et al., Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity, Int. J. Cancer 2005, 117, 356-632.
-
(2005)
Int. J. Cancer
, vol.117
, pp. 356-632
-
-
Yoxall, V.1
Kentish, P.2
Coldham, N.3
Kuhnert, N.4
-
5
-
-
68149108891
-
Modulation of rat hepatic and pulmonary cytochromes P450 and other xenobiotic-metabolising enzyme systems by the isothiocyanate erucin, a metabolite of sulforaphane
-
in press
-
Hanlon, N., Okpara, A., Coldham, N., Sauer, M. J., et al., Modulation of rat hepatic and pulmonary cytochromes P450 and other xenobiotic-metabolising enzyme systems by the isothiocyanate erucin, a metabolite of sulforaphane, J. Agric. Food Chem., in press.
-
J. Agric. Food Chem.
-
-
Hanlon, N.1
Okpara, A.2
Coldham, N.3
Sauer, M.J.4
-
6
-
-
0345303968
-
Phenethyl isothiocyanate inhibits nitrosamine carcinogenesis in a model for study of oral cancer chemoprevention
-
Solt, D. B., Chang, K., Helenowski, I., Rademaker, A. W., Phenethyl isothiocyanate inhibits nitrosamine carcinogenesis in a model for study of oral cancer chemoprevention, Cancer Lett. 2003, 202, 147-152.
-
(2003)
Cancer Lett.
, vol.202
, pp. 147-152
-
-
Solt, D.B.1
Chang, K.2
Helenowski, I.3
Rademaker, A.W.4
-
7
-
-
0036712961
-
Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung
-
Sticha, K. R., Kenney, P. M., Boysen, G., Liang, H., et al., Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung, Carcinogenesis 2002, 23, 1433-1439.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1433-1439
-
-
Sticha, K.R.1
Kenney, P.M.2
Boysen, G.3
Liang, H.4
-
8
-
-
10744226312
-
Effect of dietary constituents with chemopreventive potential on adduct formation of a low dose of the heterocyclic amines PhIP and IQ and phase II hepatic enzymes
-
Dingley, K. H., Ubick, E. A., Chiarappa-Zucca, M. L., Nowell, S., et al., Effect of dietary constituents with chemopreventive potential on adduct formation of a low dose of the heterocyclic amines PhIP and IQ and phase II hepatic enzymes, Nutr. Cancer 2003, 46, 212-221.
-
(2003)
Nutr. Cancer
, vol.46
, pp. 212-221
-
-
Dingley, K.H.1
Ubick, E.A.2
Chiarappa-Zucca, M.L.3
Nowell, S.4
-
9
-
-
0032543382
-
Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline] in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane
-
Barcelo, S., Mace, K., Pfeifer, A. M. A., Chipman, J. K., Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline] in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane, Mut. Res. 1998, 402, 111-120.
-
(1998)
Mut. Res.
, vol.402
, pp. 111-120
-
-
Barcelo, S.1
Mace, K.2
Pfeifer, A.M.A.3
Chipman, J.K.4
-
10
-
-
0346888660
-
Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes
-
Bacon, J. R., Williamson, G., Garner, R. C., Lappin, G., et al., Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes, Carcinogenesis 2003, 24, 1903-1911.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1903-1911
-
-
Bacon, J.R.1
Williamson, G.2
Garner, R.C.3
Lappin, G.4
-
11
-
-
0025809376
-
Structure-activity relationships for inhibition of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice
-
Morse, M. A., Eklind, K. I., Hecht, S. S., Jordan, K. G., et al., Structure-activity relationships for inhibition of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice, Cancer Res. 1991, 51,1846-1850.
-
(1991)
Cancer Res.
, vol.51
, pp. 1846-1850
-
-
Morse, M.A.1
Eklind, K.I.2
Hecht, S.S.3
Jordan, K.G.4
-
12
-
-
0030038193
-
Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats
-
Chung, F. L., Kelloff, G., Steele, V., Pittman, B., et al., Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats, Cancer Res. 1996, 56, 772-778.
-
(1996)
Cancer Res.
, vol.56
, pp. 772-778
-
-
Chung, F.L.1
Kelloff, G.2
Steele, V.3
Pittman, B.4
-
13
-
-
0034538640
-
Inhibition of carcinogenesis by isothiocyanates
-
Hecht, S. S., Inhibition of carcinogenesis by isothiocyanates, Drug Met. Rev. 2000, 32, 395-411.
-
(2000)
Drug Met. Rev.
, vol.32
, pp. 395-411
-
-
Hecht, S.S.1
-
14
-
-
0037058628
-
Benzyl isothiocyanate: An effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung
-
Hecht, S. S., Kenney, P. M., Wang, M., Upadhyaya, P., Benzyl isothiocyanate: An effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung, Cancer Lett. 2002,187,87-94.
-
(2002)
Cancer Lett.
, vol.187
, pp. 87-94
-
-
Hecht, S.S.1
Kenney, P.M.2
Wang, M.3
Upadhyaya, P.4
-
15
-
-
0035170990
-
Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism
-
Talalay, P., Fahey, J. W., Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism, J. Nutr. 2001, 131, 3027S-3033S.
-
(2001)
J. Nutr.
, vol.131
-
-
Talalay, P.1
Fahey, J.W.2
-
16
-
-
0032973226
-
Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: A comparison of the dynamic organ and multiwell plate culture procedures
-
Hashemi, E., Dobrota, M., Till, C., Ioannides, C., Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: A comparison of the dynamic organ and multiwell plate culture procedures, Xenobiotica 1999, 29, 11-25.
-
(1999)
Xenobiotica
, vol.29
, pp. 11-25
-
-
Hashemi, E.1
Dobrota, M.2
Till, C.3
Ioannides, C.4
-
17
-
-
0023930873
-
Direct measurement of NAD(P)H:Quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers
-
Prohaska, H. J., Santamaria, A. B., Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers, Anal. Biochem. 1988, 169, 328-336.
-
(1988)
Anal. Biochem.
, vol.169
, pp. 328-336
-
-
Prohaska, H.J.1
Santamaria, A.B.2
-
18
-
-
0016275313
-
Glutathione S-transferase, the first enzymic step in mercapturic acid formation
-
Habig, W. H., Pabst, M. J., Jakoby, W. B., Glutathione S-transferase, the first enzymic step in mercapturic acid formation, J. Biol. Chem. 1974, 249, 7130-7139.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jakoby, W.B.3
-
19
-
-
0028262418
-
Colorimetric and fluorometric assays of glutathione-S-transferase based on 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole
-
Ricci, G., Caccuri, A., Bello, M., Pastore, A., et al., Colorimetric and fluorometric assays of glutathione-S-transferase based on 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole, Anal. Biochem. 1994, 218, 463-465.
-
(1994)
Anal. Biochem.
, vol.218
, pp. 463-465
-
-
Ricci, G.1
Caccuri, A.2
Bello, M.3
Pastore, A.4
-
20
-
-
0019740345
-
Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples
-
Akerboom, T. P. H., Sies, H., Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples, Meth. Enzymol. 1981, 7, 373-382.
-
(1981)
Meth. Enzymol.
, vol.7
, pp. 373-382
-
-
Akerboom, T.P.H.1
Sies, H.2
-
21
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding
-
Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding, Anal. Biochem. 1976, 72, 248-254.
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
22
-
-
0032839441
-
Organ slices as an invitro test system for drug metabolism in human liver, lung and kidney
-
De Kanter, R., Olinga, P., De Jager, M. H., Merema, M. T., et al., Organ slices as an in invitro test system for drug metabolism in human liver, lung and kidney, Toxicol. In Vitro 1999, 13, 737-744.
-
(1999)
Toxicol. In Vitro
, vol.13
, pp. 737-744
-
-
de Kanter, R.1
Olinga, P.2
de Jager, M.H.3
Merema, M.T.4
-
23
-
-
0034676501
-
Precision-cut liver slices: Characteristics and use for in vitro pharmaco-toxicology
-
Lerche-Langrand, C., Toutain, H. J., Precision-cut liver slices: Characteristics and use for in vitro pharmaco-toxicology, Toxicology 2000, 153, 221-253.
-
(2000)
Toxicology
, vol.153
, pp. 221-253
-
-
Lerche-Langrand, C.1
Toutain, H.J.2
-
24
-
-
33846844804
-
Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S-transferase activities
-
Pushparajah, D. S., Umachandran, M., Plant, K. E., Plant, N., et al., Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S-transferase activities, Toxicology 2007, 231,68-80.
-
(2007)
Toxicology
, vol.231
, pp. 68-80
-
-
Pushparajah, D.S.1
Umachandran, M.2
Plant, K.E.3
Plant, N.4
-
25
-
-
37249077516
-
Up-regulation of CYP1A/B in rat lung and liver, and human precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size
-
Pushparajah, D. S., Umachandran, M., Nazir, T., Plant, K. E., et al., Up-regulation of CYP1A/B in rat lung and liver, and human precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size, Toxicol. In Vitro 2008, 22, 128-145.
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 128-145
-
-
Pushparajah, D.S.1
Umachandran, M.2
Nazir, T.3
Plant, K.E.4
-
26
-
-
46349100716
-
Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung
-
Pushparajah, D. S., Umachandran, M., Plant, K. E., Plant, N., et al., Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung, Mutagenesis 2008, 23, 299-308.
-
(2008)
Mutagenesis
, vol.23
, pp. 299-308
-
-
Pushparajah, D.S.1
Umachandran, M.2
Plant, K.E.3
Plant, N.4
-
27
-
-
0024465355
-
Redox and addition chemistry of quinoid compounds and its biological implications
-
Brunmark, A., Cadenas, E., Redox and addition chemistry of quinoid compounds and its biological implications, Free Rad. Biol. Med. 1989, 7, 435-477.
-
(1989)
Free Rad. Biol. Med.
, vol.7
, pp. 435-477
-
-
Brunmark, A.1
Cadenas, E.2
-
28
-
-
0002390649
-
-
in: Ioannides, C. (Ed.), John Wiley & Sons, Chichester
-
Sherrat, P. J., Hayes, J. D., in: Ioannides, C. (Ed.), Enzyme Systems That Metabolise Drugs and Other Xenobiotics, John Wiley & Sons, Chichester 2002, pp. 319-352.
-
(2002)
Enzyme Systems That Metabolise Drugs and Other Xenobiotics
, pp. 319-352
-
-
Sherrat, P.J.1
Hayes, J.D.2
-
29
-
-
0032866860
-
Stability of phase II conjugation systems in cultured precision-cut rat hepatic slices
-
Hashemi, E., Till, C., Ioannides, C., Stability of phase II conjugation systems in cultured precision-cut rat hepatic slices, Toxicol. In Vitro 1999, 13, 459-466.
-
(1999)
Toxicol. In Vitro
, vol.13
, pp. 459-466
-
-
Hashemi, E.1
Till, C.2
Ioannides, C.3
-
30
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
-
Zhang, Y., Talalay, P., Cho, G. C., Posner, G. H., A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure, Proc. Natl. Acad. Sci. 1992, 89, 2399-2403.
-
(1992)
Proc. Natl. Acad. Sci.
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, G.C.3
Posner, G.H.4
-
31
-
-
5144230473
-
Cancer-preventive isothiocyanates: Measurement of human exposure and mechanism of action
-
Zhang, Y., Cancer-preventive isothiocyanates: Measurement of human exposure and mechanism of action, Mut. Res. 2007, 555,173-190.
-
(2007)
Mut. Res.
, vol.555
, pp. 173-190
-
-
Zhang, Y.1
|