Pathogenic amyloid β-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells

Amyloid

Volumn 6, Issue 3, 1999, Pages 157-164

  Davis, Judianne ^a   Cribbs, David H ^b   Cotman, Carl W ^b   Van Nostrand, William E ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyloid protein; Apoptosis; Cerebrovascular smooth muscle cells

Indexed keywords

AMYLOID BETA PROTEIN;

APOPTOSIS; ARTICLE; BRAIN BLOOD VESSEL; CELL DEGENERATION; CELL LOSS; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; SENILE PLAQUE; SMOOTH MUSCLE FIBER;

EID: 0039228392     PISSN: 13506129     EISSN: None     Source Type: Journal    
DOI: 10.3109/13506129909007321     Document Type: Article

References (32)

1. 1 Glenner GG and Wong CW (1984). Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120, 885-890
2. 2 Glenner GG and Wong CW (1984). Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Comm 122, 1131-1135
3. 3 Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL and Beyreuther K (1985). Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 82, 4245-4269
4. 4 Su JH, Anderson AJ, Cummings BJ and Cotman CW (1994). Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 5, 2529-2533
5. 5 Lassmann HC, Bancher C, Breitschoph H, Wegiel J, Bobinski M, Jellinger K, and Wisniewski HM (1995). Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol 89, 35-41
6. 6 Portera-Cailliau C, Hedreen JC, Price DL and Koliatsos VE (1995). Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J Neurosci 15, 3775-3787
7. 7 Yoshiyama Y, Yamada T, Asanuma K and Asahi T (1994). Apoptosis related antigen, Le(Y) and nick-end labeling are positive in spinal motor neurons in amyotrophic lateral sclerosis. Acta Neuropathol (Berl). 88, 207-211
8. 8 Migheli A, Cavalla P, Marino S and Schiffer D (1994). A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks. J Neuropathol Exp Neurol 53, 606-616
9. 9 Kirschner DA, Inouye H, Duffy LK, Sinclair A, Lind M and Selkoe DJ (1987). Synthetic peptide homologous to beta protein from Alzheimer's disease forms amyloid-like fibrils in vitro. Proc Natl Acad Sci USA 84, 6953-6957
10. 10 Burdick D, Soreghan B, Kwon M, Kosmoski J, Knauer M, Henschen A, Yates J, Cotman C and Glabe C (1992). Assembly and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs. J Biol Chem 267, 546-554
11. 11 Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ and Cotman CW (1993). Apoptosis is induced by β-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci USA 90, 7951-7955
12. 12 Cotman CW and Anderson AJ (1995). A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Mol Neurobiol 10, 19-45
13. 13 Watt JA, Pike CJ, Walencewicz-Wasserman AJ and Cotman CW (1994). Ultrastructural analysis of β-amyloid-induced apoptosis in cultured hippocampal neurons. Brain Res 661, 147-156
14. 14 Copani A, Bruno V, Battaglia G, Leanza G, Pellitteri R, Russo A, Stanzani S and Nicoletti F (1995). Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by β-amyloid peptide. Mol Pharmacol 47, 890-897
15. 15 Gschwind M and Huber G (1995). Apoptotic cell death induced by β-amyloid 1-42 peptide is cell type dependent. J Neurochem 65, 292-300
16. 16 Mark RJ, Hensley K, Butterfield DA and Mattson MP (1995). Amyloid β-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death. J Neurosci 15, 6239-6249
17. 17 Paradis E, Douillard H, Koutroumanis M, Goodyer C and LeBlanc A (1996). Amyloid β peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons. J Neurosci 16, 7533-7539
18. 18 Coria, F, Larrondo-Lillo, M, and Frangione, B (1989). Degeneration of smooth muscle cells in beta-amyloid angiopathies. J Neuropathol Exper Neurol 48, 368-375
19. 19 Kawai M, Kalaria RN, Cras P, Siedlak SL, Velasco ME, Shelton ER, Chan HW, Greenberg, BD and Perry G (1993). Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Res 623, 142-146
20. 20 Wisniewski, HM, Frackowiak, J, Zoltowska, A, and Kim, KS (1994). Vascular β-amyloid in Alzheimer's disease angiopathy is produced by proliferating and degenerating smooth muscle cells. Amyloid: Int J Exp Clin Invest 1, 8-16
21. 21 Davis-Salinas J, Saporito-Irwin SM, Cotman CW and Van Nostrand WE (1995). Amyloid β-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. J.Neurochem 65, 931-934
22. 22 Davis-Salinas J and Van Nostrand WE (1995). Aggregation of amyloid β-protein nullifies its pathologic properties in cultured cerebrovascular smooth muscle cells. J Biol Chem 270, 20887-20890
23. 23 Davis, J and Van Nostrand, WE (1996). Enhanced pathologic properties of Dutch-type mutant amyloid β-protein. Proc Natl Acad Sci USA 93, 2996-3000
24. 24 Rozemuller AJM, Roos RAC, Bots GTAM, Kamphorst W, Eikelenboom P and Van Nostrand WE (1993). Distribution of β/A4 and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease. Am J Pathol 142, 1449-1457
25. 25 Wattendorff AR, Frangione B, Luyendijk W and Bots GTAM (1995). Hereditary cerebral haemorrhage with amyloidosis, Dutch type (HCHWA-D): clinicopathological studies. J Neurol Neurosurg Psychiatry 59, 699-705
26. 26 Van Nostrand WE, Melchor J and Ruffini L (1998) Pathogenic Cell Surface Amyloid β-Protein Fibril Assembly in Cultured Human Cerebrovascular Smooth Muscle Cells. J Neurochem 70, 216-223
27. 27 Van Nostrand WE, Rozemuller AJM, Chung R, Cotman CW and Saporito-Irwin SM (1994). Amyloid β-protein precursor in cultured leptomeningeal smooth muscle cells. Amyloid: Int J Exp Clin Invest 1, 1-7
28. 28 Bradford MM (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal Biochem 72, 248-254
29. 29 Yang F, Sun X, Beech W, Teter B, Wu S, Sigel J, Vinters H, Frautschy S and Cole G (1998). Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma cells and plaque-associated neurons and microglia in Alzheimer's disease. Am J Pathol 152, 379-389
30. 30 Alnemri ES (1997). Mammalian cell death protease: a family of highly conserved aspartate specific cysteine proteases. J Cell Biochem 64, 33-42
31. 31 Hase M, Araki S and Hayashi H (1997). Fragments of amyloid beta induce apoptosis in vascular endothelial cells. Endothelium 5, 221-229
32. 32 Blanc EM, Toborek M, Mark RJ, Hennig B and Mattson MP (1997). Amyloid β-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells. J Neurochem 68, 1870-1881