Amoxapine inhibits the delayed rectifier outward k+ current in mouse cortical neurons via cAMP/protein kinase a pathways

Journal of Pharmacology and Experimental Therapeutics

Volumn 332, Issue 2, 2010, Pages 437-445

  He, Yan Lin ^a   Zhan, Xiao Qin ^a   Yang, Guang ^a   Sun, Ji ^a   Mei, Yan Ai ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXAPINE; ANTIDEPRESSANT AGENT; BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DELAYED RECTIFIER POTASSIUM CHANNEL; FORSKOLIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); N [2 (P BROMOCINNAMYLAMINO)ETHYL] 5 ISO QUINOLINESULPHONAMIDE; SEROTONIN; SEROTONIN 2 RECEPTOR; SEROTONIN RECEPTOR; SHAB POTASSIUM CHANNEL; SULFONAMIDE; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; IMMUNOHISTOCHEMISTRY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEADY STATE;

AMOXAPINE; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CELL CULTURE TECHNIQUES; CEREBRAL CORTEX; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DELAYED RECTIFIER POTASSIUM CHANNELS; DRUG INTERACTIONS; MEMBRANE POTENTIALS; MICE; NEURONS; RECEPTORS, SEROTONIN, 5-HT2; SHAB POTASSIUM CHANNELS; SIGNAL TRANSDUCTION;

EID: 76749093565     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.159160     Document Type: Article

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