Inhibition of astroglial inwardly rectifying Kir4.1 channels by a tricyclic antidepressant, nortriptyline

Journal of Pharmacology and Experimental Therapeutics

Volumn 320, Issue 2, 2007, Pages 573-580

  Su, Suwen ^a   Ohno, Yukihiro ^a   Lossin, Christoph ^a   Hibino, Hiroshi ^a   Inanobe, Atsushi ^a   Kurachi, Yoshihisa ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; DESIPRAMINE; IMIPRAMINE; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL KIR4.1; NORTRIPTYLINE; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL STRAIN HEK293; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; DRUG PENETRATION; ELECTRIC POTENTIAL; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; MACROGLIA; NERVE CELL; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; WHOLE CELL;

ANTIDEPRESSIVE AGENTS, TRICYCLIC; ASTROCYTES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KINETICS; NORTRIPTYLINE; POTASSIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING;

EID: 33846413540     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.112094     Document Type: Article

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