Pharmacological characterisation of the human small conductance calcium-activated potassium channel hSK3 reveals sensitivity to tricyclic antidepressants and antipsychotic phenothiazines

Neuropharmacology

Volumn 40, Issue 6, 2001, Pages 772-783

  Terstappen, G C ^a   Pula, G ^a   Carignani, C ^a   Chen, M X ^b   Roncarati, R ^c  

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Univ V   (Italy)

Author keywords

125I Apamin binding; DiBAC4(3); Human small conductance calcium activated potassium channel SK3 (hSK3); Phenothiazines; Protein phosphatase inhibitors; Tricyclic antidepressants

Indexed keywords

ANTIBODY; APAMIN; CALYCULIN A; CHARYBDOTOXIN; CHLORPROMAZINE; DEQUALINIUM; DESIPRAMINE; FLUORESCENT DYE; FLUPHENAZINE; IBERIOTOXIN; IMIPRAMINE; IODINE 125; IONOMYCIN; NEUROLEPTIC AGENT; NORTRIPTYLINE; NOXIUSTOXIN; OKADAIC ACID; PHENOTHIAZINE DERIVATIVE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROMETHAZINE; RADIOLIGAND; TRICYCLIC ANTIDEPRESSANT AGENT; TRIFLUOPERAZINE; TUBOCURARINE CHLORIDE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; CHANNEL GATING; CHO CELL; COMPETITIVE INHIBITION; DRUG POTENCY; DRUG SENSITIVITY; IC 50; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOFLUORESCENCE TEST; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ANTIPSYCHOTIC AGENTS; APAMIN; CHO CELLS; CRICETINAE; HUMANS; PHENOTHIAZINES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS;

EID: 0035012655     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00007-7     Document Type: Article

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