Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events

Journal of Cell Science

Volumn 123, Issue 3, 2010, Pages 401-412

  Struckhoff, Amanda P ^a   Vitko, Jason R ^a   Rana, Manish K ^a   Davis, Carter T ^a   Foderingham, Kamau E ^a   Liu, Chi Hsin ^a   Vanhoy Rhodes, Lyndsay ^b   Elliot, Steven ^b   Zhu, Yun ^b   Burow, Matt ^b   Worthylake, Rebecca A ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CXCL12; CXCR4; Flow; Metastasis; ROCK; Tumor recruitment

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CHEMOKINE RECEPTOR CXCR4; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; LAMININ; PAXILLIN; PROTEIN ROCK; PROTEIN SERINE THREONINE KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ZYXIN;

ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REACTIVATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHEAR STRESS; SIGNAL TRANSDUCTION; TUMOR CELL;

AMIDES; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CXCL12; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICROSCOPY, FLUORESCENCE; PYRIDINES; RECEPTORS, CXCR4; RHO-ASSOCIATED KINASES;

EID: 76649108219     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.052167     Document Type: Article

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