Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions

European Journal of Pharmacology

Volumn 459, Issue 2-3, 2003, Pages 113-120

  Nakajima, Masahide ^a   Hayashi, Kazutaka ^a   Katayama, Ken ichi ^a   Amano, Yusaku ^a   Egi, Yasuhiro ^a   Uehata, Masayoshi ^a   Goto, Nobuharu ^a   Kondo, Takao ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Angiogenesis; Endothelial cell; Invasion; Migration; Tumor metastasis; Wf 536

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)BENZAMIDE MONOHYDROCHLORIDE; ANTIMETASTATIC AGENT; MATRIGEL; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; WF 536;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEWIS CARCINOMA; METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; CARCINOMA, LEWIS LUNG; CELL MIGRATION INHIBITION; CELL MOVEMENT; CELLS, CULTURED; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES;

EID: 0037449474     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02869-8     Document Type: Article

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