Structure-activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril cores

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 5, 2010, Pages 1555-1558

  Fensome, Andrew ^a   Goldberg, Joel ^a   McComas, Casey C ^a   Trybulski, Eugene J ^a   Woodworth, Richard P ^a   Deecher, Darlene C ^a   Whiteside, Garth T ^a   Zhang, Puwen ^a  

^a PFIZER INC   (United States)

Author keywords

Monoamine reuptake inhibitor; Norepinephrine reuptake inhibitor

Indexed keywords

BENZOTHIADIAZINE DERIVATIVE; DOPAMINE TRANSPORTER; MONOAMINE; NORADRENALIN UPTAKE INHIBITOR; SEROTONIN;

ARTICLE; IN VITRO STUDY; IN VIVO STUDY; MICROSOME; SCREENING; STRUCTURE ACTIVITY RELATION; SYNTHESIS; THERMOREGULATION;

ADRENERGIC UPTAKE INHIBITORS; ANIMALS; BENZOTHIADIAZINES; BIOLOGICAL TRANSPORT; CYCLIC S-OXIDES; HUMANS; MICROSOMES, LIVER; MODELS, ANIMAL; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZINES;

EID: 76649086971     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.01.056     Document Type: Article

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