1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 20, 2005, Pages 4432-4437

  Beadle, Christopher D ^a   Boot, John ^a   Camp, Nicholas P ^a   Dezutter, Nancy ^b   Findlay, Jeremy ^a   Hayhurst, Lorna ^a   Masters, John J ^a   Penariol, Roberta ^a   Walter, Magnus W ^a  

^a ELI LILLY AND COMPANY   (United States)

^b Eli Lilly Benelux   (Belgium)

Author keywords

Monoamine reuptake inhibitors; Norepinephrine; Pharmacophore; Quinolin 2 one; SAR; Selective norepinephrine reuptake inhibitor

Indexed keywords

ATOMOXETINE; CITALOPRAM; DULOXETINE; FLUOXETINE; NISOXETINE; NORADRENALIN UPTAKE INHIBITOR; QUINOLONE DERIVATIVE; REBOXETINE;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TARGETING; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; NEUROTRANSMITTER UPTAKE INHIBITORS; NOREPINEPHRINE; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 24344482127     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.038     Document Type: Article

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