-
1
-
-
0028972025
-
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 1995;83:803-812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
2
-
-
0032173439
-
The nuclear receptor PPARgamma- bigger than fat
-
Kliewer SA, Willson TM. The nuclear receptor PPARgamma- bigger than fat. Curr Opin Genet Dev. 1998;8:576-581.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 576-581
-
-
Kliewer, S.A.1
Willson, T.M.2
-
3
-
-
0035851187
-
PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM. PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem. 2001;276:37731-37734.
-
(2001)
J Biol Chem
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
4
-
-
0142210246
-
Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: Association with extracellular signal-regulated kinase signal pathway
-
Kim EJ, Park KS, Chung SY, Sheen YY, Moon DC, Song YS, Kim KS, Song S, Yun YP, Lee MK, Oh KW, Yoon do Y, Hong JT. Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: Association with extracellular signal-regulated kinase signal pathway. J Pharmacol Exp Ther. 2003;307:505-517.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 505-517
-
-
Kim, E.J.1
Park, K.S.2
Chung, S.Y.3
Sheen, Y.Y.4
Moon, D.C.5
Song, Y.S.6
Kim, K.S.7
Song, S.8
Yun, Y.P.9
Lee, M.K.10
Oh, K.W.11
Yoon Do, Y.12
Hong, J.T.13
-
5
-
-
0033546710
-
Troglitazone suppresses cell growth of myeloid leukemia cell lines by induction of p21WAF1/CIP1 cyclin-dependent kinase inhibitor
-
Sugimura A, Kiriyama Y, Nochi H, Tsuchiya H, Tamoto K, Sakurada Y, Ui M, Tokumitsu Y. Troglitazone suppresses cell growth of myeloid leukemia cell lines by induction of p21WAF1/CIP1 cyclin-dependent kinase inhibitor. Biochem Biophys Res Commun. 1999;261:833-837.
-
(1999)
Biochem Biophys Res Commun
, vol.261
, pp. 833-837
-
-
Sugimura, A.1
Kiriyama, Y.2
Nochi, H.3
Tsuchiya, H.4
Tamoto, K.5
Sakurada, Y.6
Ui, M.7
Tokumitsu, Y.8
-
6
-
-
0035831025
-
Toxic effect of troglitazone on cultured rat hepatocytes
-
Toyoda Y, Tsuchida A, Iwami E, Miwa I. Toxic effect of troglitazone on cultured rat hepatocytes. Life Sci. 2001; 68:1867-1876.
-
(2001)
Life Sci
, vol.68
, pp. 1867-1876
-
-
Toyoda, Y.1
Tsuchida, A.2
Iwami, E.3
Miwa, I.4
-
7
-
-
34047143137
-
Role of mitogen-activated protein kinase (MAPK) in troglitazone- induced osteoblastic cell death
-
Jung JY, Yoo CI, Kim HT, Kwon CH, Park JY, Kim YK. Role of mitogen-activated protein kinase (MAPK) in troglitazone- induced osteoblastic cell death. Toxicology. 2007; 234:73-82.
-
(2007)
Toxicology
, vol.234
, pp. 73-82
-
-
Jung, J.Y.1
Yoo, C.I.2
Kim, H.T.3
Kwon, C.H.4
Park, J.Y.5
Kim, Y.K.6
-
8
-
-
38949150006
-
Ciglitazone induces caspase-independent apoptosis through downregulation of XIAP and surviving in human glioma cells
-
Kang DW, Choi CH, Park JY, Kang SK, Kim YK: Ciglitazone induces caspase-independent apoptosis through downregulation of XIAP and surviving in human glioma cells. Neurochem Res. 2008;33:551-561.
-
(2008)
Neurochem Res
, vol.33
, pp. 551-561
-
-
Kang, D.W.1
Choi, C.H.2
Park, J.Y.3
Kang, S.K.4
Kim, Y.K.5
-
9
-
-
43849099390
-
15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells
-
Lee SJ, Kim MS, Park JY, Woo JS, Kim YK. 15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells. Toxicology. 2008; 248:121-129.
-
(2008)
Toxicology
, vol.248
, pp. 121-129
-
-
Lee, S.J.1
Kim, M.S.2
Park, J.Y.3
Woo, J.S.4
Kim, Y.K.5
-
10
-
-
0037262092
-
Negative growth effects of ciglitazone on kidney interstitial fibroblasts: Role of PPAR-gamma
-
Parameswaran N, Hall CS, Bomberger JM, Sparks HV, Jump DB, Spielman WS. Negative growth effects of ciglitazone on kidney interstitial fibroblasts: Role of PPAR-gamma. Kidney Blood Press Res. 2003;26:2-9.
-
(2003)
Kidney Blood Press Res
, vol.26
, pp. 2-9
-
-
Parameswaran, N.1
Hall, C.S.2
Bomberger, J.M.3
Sparks, H.V.4
Jump, D.B.5
Spielman, W.S.6
-
11
-
-
20544469044
-
Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts
-
Zafiriou S, Stanners SR, Saad S, Polhill TS, Poronnik P, Pollock CA. Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts. J Am Soc Nephrol. 2005;16:638-645.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 638-645
-
-
Zafiriou, S.1
Stanners, S.R.2
Saad, S.3
Polhill, T.S.4
Poronnik, P.5
Pollock, C.A.6
-
12
-
-
9644254466
-
Stimulation of proximal tubular cell apoptosis by albuminbound fatty acids mediated by peroxisome proliferator activated receptor-gamma
-
Arici M, Chana R, Lewington A, Brown J, Brunskill NJ. Stimulation of proximal tubular cell apoptosis by albuminbound fatty acids mediated by peroxisome proliferator activated receptor-gamma. J Am Soc Nephrol. 2003;14:17-27.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 17-27
-
-
Arici, M.1
Chana, R.2
Lewington, A.3
Brown, J.4
Brunskill, N.J.5
-
13
-
-
33750036728
-
15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism
-
Kang DS, Kwon CH, Park JY, Kim JH, Woo JS, Jung JS, Kim YK. 15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism. Toxicol Appl Pharmacol. 2006;216:426-435.
-
(2006)
Toxicol Appl Pharmacol
, vol.216
, pp. 426-435
-
-
Kang, D.S.1
Kwon, C.H.2
Park, J.Y.3
Kim, J.H.4
Woo, J.S.5
Jung, J.S.6
Kim, Y.K.7
-
14
-
-
37549025332
-
Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells
-
Kwon CH, Yoon CS, Kim YK. Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells. Toxicology. 2007;244:13-24.
-
(2007)
Toxicology
, vol.244
, pp. 13-24
-
-
Kwon, C.H.1
Yoon, C.S.2
Kim, Y.K.3
-
15
-
-
34547812041
-
Cytotoxicity of peroxisome proliferator-activated receptor alpha and gamma agonists in renal proximal tubular cell lines
-
Giral H, Villa-Bellosta R, Catalan J, Sorribas V: Cytotoxicity of peroxisome proliferator-activated receptor alpha and gamma agonists in renal proximal tubular cell lines. Toxicol In Vitro. 2007;21:1066-1076.
-
(2007)
Toxicol in Vitro
, vol.21
, pp. 1066-1076
-
-
Giral, H.1
Villa-Bellosta, R.2
Catalan, J.3
Sorribas, V.4
-
16
-
-
2442678866
-
Differential effects of peroxisome proliferator activated receptor-gamma (PPAR gamma) ligands in proximal tubular cells: Thiazolidinediones are partial PPAR gamma agonists
-
Chana RS, Lewington AJ, Brunskill NJ. Differential effects of peroxisome proliferator activated receptor-gamma (PPAR gamma) ligands in proximal tubular cells: Thiazolidinediones are partial PPAR gamma agonists. Kidney Int. 2004; 65:2081-2090.
-
(2004)
Kidney Int
, vol.65
, pp. 2081-2090
-
-
Chana, R.S.1
Lewington, A.J.2
Brunskill, N.J.3
-
17
-
-
0043074753
-
Troglitazone inhibits isolated cell proliferation, and induces apoptosis in isolated rat mesangial cells
-
Tsuchiya T, Shimizu H, Shimomura K, Mori M. Troglitazone inhibits isolated cell proliferation, and induces apoptosis in isolated rat mesangial cells. Am J Nephrol. 2003;23: 222-228.
-
(2003)
Am J Nephrol
, vol.23
, pp. 222-228
-
-
Tsuchiya, T.1
Shimizu, H.2
Shimomura, K.3
Mori, M.4
-
18
-
-
34547629755
-
Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury
-
Doi S, Masaki T, Arakawa T, Takahashi S, Kawai T, Nakashima A, Naito T, Kohno N, Yorioka N. Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury. Transplantation. 2007; 84:207-213.
-
(2007)
Transplantation
, vol.84
, pp. 207-213
-
-
Doi, S.1
Masaki, T.2
Arakawa, T.3
Takahashi, S.4
Kawai, T.5
Nakashima, A.6
Naito, T.7
Kohno, N.8
Yorioka, N.9
-
19
-
-
0043074737
-
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury
-
Sivarajah A, Chatterjee PK, Patel NS, Todorovic Z, Hattori Y, Brown PA, Stewart KN, Mota-Filipe H, Cuzzocrea S, Thiemermann C: Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury. Am J Nephrol. 2003;23:267-276.
-
(2003)
Am J Nephrol
, vol.23
, pp. 267-276
-
-
Sivarajah, A.1
Chatterjee, P.K.2
Patel, N.S.3
Todorovic, Z.4
Hattori, Y.5
Brown, P.A.6
Stewart, K.N.7
Mota-Filipe, H.8
Cuzzocrea, S.9
Thiemermann, C.10
-
20
-
-
20344380466
-
Expression of peroxisome proliferator-activated receptor-gamma in renal ischemia-reperfusion injury
-
Matsuyama M, Yoshimura R, Hase T, Uchida J, Tsuchida K, Takemoto Y, Kawahito Y, Sano H, Nakatani T. Expression of peroxisome proliferator-activated receptor-gamma in renal ischemia-reperfusion injury. Transplant Proc. 2005;37: 1684-1685.
-
(2005)
Transplant Proc
, vol.37
, pp. 1684-1685
-
-
Matsuyama, M.1
Yoshimura, R.2
Hase, T.3
Uchida, J.4
Tsuchida, K.5
Takemoto, Y.6
Kawahito, Y.7
Sano, H.8
Nakatani, T.9
-
21
-
-
34547128115
-
Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol- induced acute renal failure
-
Yousefipour Z, Hercule H, Truong L, Oyekan A, Newaz M. Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol- induced acute renal failure. J Pharmacol Exp Ther. 2007;322:461-468.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 461-468
-
-
Yousefipour, Z.1
Hercule, H.2
Truong, L.3
Oyekan, A.4
Newaz, M.5
-
22
-
-
34147213227
-
Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation
-
Ohga S, Shikata K, Yozai K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H. Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation. Am J Physiol Renal Physiol. 2007;292: F1141-1150.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Ohga, S.1
Shikata, K.2
Yozai, K.3
Okada, S.4
Ogawa, D.5
Usui, H.6
Wada, J.7
Shikata, Y.8
Makino, H.9
-
23
-
-
33748335467
-
Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms
-
Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H. Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms. Diabetes. 2006;55:1666-1677.
-
(2006)
Diabetes
, vol.55
, pp. 1666-1677
-
-
Okada, T.1
Wada, J.2
Hida, K.3
Eguchi, J.4
Hashimoto, I.5
Baba, M.6
Yasuhara, A.7
Shikata, K.8
Makino, H.9
-
24
-
-
14444281382
-
Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma
-
Young PW, Buckle DR, Cantello BC, Chapman H, Clapham JC, Coyle PJ, Haigh D, Hindley RM, Holder JC, Kallender H, Latter AJ, Lawrie KW, Mossakowska D, Murphy GJ, Roxbee Cox L, Smith SA. Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma. J Pharmacol Exp Ther. 1998;284:751-759.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 751-759
-
-
Young, P.W.1
Buckle, D.R.2
Cantello, B.C.3
Chapman, H.4
Clapham, J.C.5
Coyle, P.J.6
Haigh, D.7
Hindley, R.M.8
Holder, J.C.9
Kallender, H.10
Latter, A.J.11
Lawrie, K.W.12
Mossakowska, D.13
Murphy, G.J.14
Roxbee Cox, L.15
Smith, S.A.16
-
25
-
-
0031847401
-
Peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats
-
Buckingham RE, Al-Barazanji KA, Toseland CD, Slaughter M, Connor SC, West A, Bond B, Turner NC, Clapham JC. Peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats. Diabetes. 1998;47: 1326-1334.
-
(1998)
Diabetes
, vol.47
, pp. 1326-1334
-
-
Buckingham, R.E.1
Al-Barazanji, K.A.2
Toseland, C.D.3
Slaughter, M.4
Connor, S.C.5
West, A.6
Bond, B.7
Turner, N.C.8
Clapham, J.C.9
-
26
-
-
0345599866
-
Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity
-
Baylis C, Atzpodien EA, Freshour G, Engels K. Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity. J Pharmacol Exp Ther. 2003;307:854-860.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 854-860
-
-
Baylis, C.1
Atzpodien, E.A.2
Freshour, G.3
Engels, K.4
-
27
-
-
33748056444
-
Rosiglitazone ameliorates cisplatin-induced renal injury in mice
-
Lee S, Kim W, Moon SO, Sung MJ, Kim DH, Kang KP, Jang YB, Lee JE, Jang KY, Park SK. Rosiglitazone ameliorates cisplatin-induced renal injury in mice. Nephrol Dial Transplant. 2006;21:2096-2105.
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 2096-2105
-
-
Lee, S.1
Kim, W.2
Moon, S.O.3
Sung, M.J.4
Kim, D.H.5
Kang, K.P.6
Jang, Y.B.7
Lee, J.E.8
Jang, K.Y.9
Park, S.K.10
-
28
-
-
33947279878
-
Rosiglitazone prevents advanced glycation end products-induced renal toxicity likely through suppression of plasminogen activator inhibitor-1
-
Yu X, Li C, Li X, Cai L. Rosiglitazone prevents advanced glycation end products-induced renal toxicity likely through suppression of plasminogen activator inhibitor-1. Toxicol Sci. 2007;96:346-356.
-
(2007)
Toxicol Sci
, vol.96
, pp. 346-356
-
-
Yu, X.1
Li, C.2
Li, X.3
Cai, L.4
-
29
-
-
34447545820
-
Rosiglitazone increases PPAR gamma in renal tubular epithelial cells and protects against damage by hydrogen peroxide
-
Sommer M, Wolf G. Rosiglitazone increases PPARgamma in renal tubular epithelial cells and protects against damage by hydrogen peroxide. Am J Nephrol. 2007;27:425-434.
-
(2007)
Am J Nephrol
, vol.27
, pp. 425-434
-
-
Sommer, M.1
Wolf, G.2
-
30
-
-
0041382970
-
Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells
-
Nowak G, Price PM, Schnellmann RG. Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells. Am J Physiol Renal Physiol. 2003;285:F440-F450.
-
(2003)
Am J Physiol Renal Physiol
, vol.285
-
-
Nowak, G.1
Price, P.M.2
Schnellmann, R.G.3
-
31
-
-
5144223523
-
The induction of cell cycle regulatory and DNA repair proteins in cisplatininduced acute renal failure
-
Zhou H, Kato A, Yasuda H, Miyaji T, Fujigaki Y, Yamamoto T, Yonemura K, Hishida A. The induction of cell cycle regulatory and DNA repair proteins in cisplatininduced acute renal failure. Toxicol Appl Pharmacol. 2004;200:111-120.
-
(2004)
Toxicol Appl Pharmacol
, vol.200
, pp. 111-120
-
-
Zhou, H.1
Kato, A.2
Yasuda, H.3
Miyaji, T.4
Fujigaki, Y.5
Yamamoto, T.6
Yonemura, K.7
Hishida, A.8
-
32
-
-
0035040940
-
Role of the increase in p21 in cisplatin-induced acute renal failure in rats
-
Miyaji T, Kato A, Yasuda H, Fujigaki Y, Hishida A. Role of the increase in p21 in cisplatin-induced acute renal failure in rats. J Am Soc Nephrol. 2001;12:900-908.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 900-908
-
-
Miyaji, T.1
Kato, A.2
Yasuda, H.3
Fujigaki, Y.4
Hishida, A.5
-
33
-
-
0032519006
-
Induction of p21WAF1/ CIP1/SDI1 in kidney tubule cells affects the course of cisplatin- induced acute renal failure
-
Megyesi J, Safirstein RL, Price PM. Induction of p21WAF1/ CIP1/SDI1 in kidney tubule cells affects the course of cisplatin- induced acute renal failure. J Clin Invest. 1998;101: 777-782.
-
(1998)
J Clin Invest
, vol.101
, pp. 777-782
-
-
Megyesi, J.1
Safirstein, R.L.2
Price, P.M.3
-
34
-
-
0035176512
-
Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure
-
Megyesi J, Andrade L, Vieira JM Jr, Safirstein RL, Price PM. Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure. Kidney Int. 2001;60:2164-2172.
-
(2001)
Kidney Int
, vol.60
, pp. 2164-2172
-
-
Megyesi, J.1
Andrade, L.2
Vieira Jr., J.M.3
Safirstein, R.L.4
Price, P.M.5
-
35
-
-
33646198038
-
Apoptosis and proliferation of cultured mesangial cells isolated from kidneys of rosiglitazone-treated pregnant diabetic rats
-
Weissgarten J, Berman S, Efrati S, Rapoport M, Averbukh Z, Feldman L. Apoptosis and proliferation of cultured mesangial cells isolated from kidneys of rosiglitazone-treated pregnant diabetic rats. Nephrol Dial Transplant. 2006;21:1198-1204.
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 1198-1204
-
-
Weissgarten, J.1
Berman, S.2
Efrati, S.3
Rapoport, M.4
Averbukh, Z.5
Feldman, L.6
-
36
-
-
34547445697
-
PPAR-gamma activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats
-
Efrati S, Berman S, Ilgiyeav E, Averbukh Z, Weissgarten J. PPAR-gamma activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats. Nephron Exp Nephrol. 2007;106: e107-e112.
-
(2007)
Nephron Exp Nephrol
, vol.106
-
-
Efrati, S.1
Berman, S.2
Ilgiyeav, E.3
Averbukh, Z.4
Weissgarten, J.5
-
37
-
-
9344263462
-
Ligands of peroxisome proliferator-activated receptor gamma induce apoptosis in multiple myeloma
-
Eucker J, Bangeroth K, Zavrski I, Krebbel H, Zang C, Heider U, Jakob C, Elstner E, Possinger K, Sezer O. Ligands of peroxisome proliferator-activated receptor gamma induce apoptosis in multiple myeloma. Anticancer Drugs. 2004;15: 955-960.
-
(2004)
Anticancer Drugs
, vol.15
, pp. 955-960
-
-
Eucker, J.1
Bangeroth, K.2
Zavrski, I.3
Krebbel, H.4
Zang, C.5
Heider, U.6
Jakob, C.7
Elstner, E.8
Possinger, K.9
Sezer, O.10
-
38
-
-
11344266106
-
The PPAR gamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines
-
Morosetti R, Servidei T, Mirabella M, Rutella S, Mangiola A, Maira G, Mastrangelo R, Koeffler HP. The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines. Int J Oncol. 2004;25: 493-502.
-
(2004)
Int J Oncol
, vol.25
, pp. 493-502
-
-
Morosetti, R.1
Servidei, T.2
Mirabella, M.3
Rutella, S.4
Mangiola, A.5
Maira, G.6
Mastrangelo, R.7
Koeffler, H.P.8
-
39
-
-
9644295737
-
Ligand-independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: Dependent on phosphatidylinositol 3-kinase activity
-
Al-Rasheed NM, Chana RS, Baines RJ, Willars GB, Brunskill NJ. Ligand-independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: Dependent on phosphatidylinositol 3-kinase activity. J Biol Chem. 2004;279:49747-49754.
-
(2004)
J Biol Chem
, vol.279
, pp. 49747-49754
-
-
Al-Rasheed, N.M.1
Chana, R.S.2
Baines, R.J.3
Willars, G.B.4
Brunskill, N.J.5
-
40
-
-
0034306996
-
The Rb/E2F pathway: Expanding roles and emerging paradigms
-
Harbour JW, Dean DC. The Rb/E2F pathway: Expanding roles and emerging paradigms. Genes Dev. 2000;14:2393-2409.
-
(2000)
Genes Dev
, vol.14
, pp. 2393-2409
-
-
Harbour, J.W.1
Dean, D.C.2
-
41
-
-
0031425276
-
PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF
-
Choudhury GG, Karamitsos C, Hernandez J, Gentilini A, Bardgette J, Abboud HE. PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF. Am J Physiol. 1997;273:F931-F938.
-
(1997)
Am J Physiol
, vol.273
-
-
Choudhury, G.G.1
Karamitsos, C.2
Hernandez, J.3
Gentilini, A.4
Bardgette, J.5
Abboud, H.E.6
-
42
-
-
0033618410
-
Multiple ras effector pathways contribute to G(1) cell cycle progression
-
Gille H, Downward J. Multiple ras effector pathways contribute to G(1) cell cycle progression. J Biol Chem. 1999; 274:22033-22040.
-
(1999)
J Biol Chem
, vol.274
, pp. 22033-22040
-
-
Gille, H.1
Downward, J.2
-
43
-
-
33748063941
-
Roles of the RAF/MEK/ERK and PI3K/PTEN/ AKT pathways in malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M. Roles of the RAF/MEK/ERK and PI3K/PTEN/ AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul. 2006;46:249-279.
-
(2006)
Adv Enzyme Regul
, vol.46
, pp. 249-279
-
-
McCubrey, J.A.1
Steelman, L.S.2
Abrams, S.L.3
Lee, J.T.4
Chang, F.5
Bertrand, F.E.6
Navolanic, P.M.7
Terrian, D.M.8
Franklin, R.A.9
D'Assoro, A.B.10
Salisbury, J.L.11
Mazzarino, M.C.12
Stivala, F.13
Libra, M.14
-
44
-
-
34250013383
-
PPAR-gamma agonist protects podocytes from injury
-
Kanjanabuch T, Ma LJ, Chen J, Pozzi A, Guan Y, Mundel P, Fogo AB. PPAR-gamma agonist protects podocytes from injury. Kidney Int. 2007;71:1232-1239.
-
(2007)
Kidney Int
, vol.71
, pp. 1232-1239
-
-
Kanjanabuch, T.1
Ma, L.J.2
Chen, J.3
Pozzi, A.4
Guan, Y.5
Mundel, P.6
Fogo, A.B.7
-
45
-
-
0035089354
-
Troglitazone and rosiglitazone induce apoptosis of vascular smooth muscle cells through an extracellular signal-regulated kinase-independent pathway
-
DOI 10.1007/s002100000352
-
Gouni-Berthold I, Berthold HK, Weber AA, Ko Y, Seul C, Vetter H, Sachinidis A. Troglitazone and rosiglitazone induce apoptosis of vascular smooth muscle cells through an extracellular signal-regulated kinase-independent pathway. Naunyn Schmiedebergs Arch Pharmacol. 2001;363: 215-221. (Pubitemid 32200330)
-
(2001)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.363
, Issue.2
, pp. 215-221
-
-
Gouni-Berthold, I.1
Berthold, H.K.2
Weber, A.-A.3
Ko, Y.4
Seul, C.5
Vetter, H.6
Sachinidis, A.7
-
46
-
-
0034698074
-
Peroxisome proliferator-activated receptor gamma ligands inhibit retinoblastoma phosphorylation and G1'S transition in vascular smooth muscle cells
-
Wakino S, Kintscher U, Kim S, Yin F, Hsueh WA, Law RE. Peroxisome proliferator-activated receptor gamma ligands inhibit retinoblastoma phosphorylation and G1'S transition in vascular smooth muscle cells. J Biol Chem. 2000;275: 22435-22441.
-
(2000)
J Biol Chem
, vol.275
, pp. 22435-22441
-
-
Wakino, S.1
Kintscher, U.2
Kim, S.3
Yin, F.4
Hsueh, W.A.5
Law, R.E.6
-
47
-
-
0032475922
-
Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages
-
Chinetti G, Griglio S, Antonucci M, Torra IP, Delerive P, Majd Z, Fruchart JC, Chapman J, Najib J, Staels B. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. J Biol Chem. 1998;273:25573-25580.
-
(1998)
J Biol Chem
, vol.273
, pp. 25573-25580
-
-
Chinetti, G.1
Griglio, S.2
Antonucci, M.3
Torra, I.P.4
Delerive, P.5
Majd, Z.6
Fruchart, J.C.7
Chapman, J.8
Najib, J.9
Staels, B.10
-
48
-
-
0035497756
-
PPAR gamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in rastransformed rat intestinal epithelial cells
-
Kitamura S, Miyazaki Y, Hiraoka S, Nagasawa Y, Toyota M, Takakura R, Kiyohara T, Shinomura Y, Matsuzawa Y. PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in rastransformed rat intestinal epithelial cells. Int J Cancer. 2001; 94:335-342.
-
(2001)
Int J Cancer
, vol.94
, pp. 335-342
-
-
Kitamura, S.1
Miyazaki, Y.2
Hiraoka, S.3
Nagasawa, Y.4
Toyota, M.5
Takakura, R.6
Kiyohara, T.7
Shinomura, Y.8
Matsuzawa, Y.9
-
49
-
-
0035019640
-
Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells
-
Ohta K, Endo T, Haraguchi K, Hershman JM, Onaya T. Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells. J Clin Endocrinol Metab. 2001; 86:2170-2177.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 2170-2177
-
-
Ohta, K.1
Endo, T.2
Haraguchi, K.3
Hershman, J.M.4
Onaya, T.5
-
50
-
-
1542268988
-
Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion
-
Liu HR, Tao L, Gao E, Lopez BL, Christopher TA, Willette RN, Ohlstein EH, Yue TL, Ma XL. Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion. Cardiovasc Res. 2004; 62:135-144.
-
(2004)
Cardiovasc Res
, vol.62
, pp. 135-144
-
-
Liu, H.R.1
Tao, L.2
Gao, E.3
Lopez, B.L.4
Christopher, T.A.5
Willette, R.N.6
Ohlstein, E.H.7
Yue, T.L.8
Ma, X.L.9
-
51
-
-
20444398490
-
Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation
-
Luna-Medina R, Cortes-Canteli M, Alonso M, Santos A, Martinez A, Perez-Castillo A. Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation. J Biol Chem. 2005;280:21453-21462.
-
(2005)
J Biol Chem
, vol.280
, pp. 21453-21462
-
-
Luna-Medina, R.1
Cortes-Canteli, M.2
Alonso, M.3
Santos, A.4
Martinez, A.5
Perez-Castillo, A.6
-
52
-
-
1542329710
-
PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms
-
Ward JE, Gould H, Harris T, Bonacci JV, Stewart AG. PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms. Br J Pharmacol. 2004;141:517-525.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 517-525
-
-
Ward, J.E.1
Gould, H.2
Harris, T.3
Bonacci, J.V.4
Stewart, A.G.5
-
53
-
-
0037699445
-
PPARgamma controls cell proliferation and apoptosis in an RB-dependent manner
-
Fajas L, Egler V, Reiter R, Miard S, Lefebvre AM, Auwerx J. PPARgamma controls cell proliferation and apoptosis in an RB-dependent manner. Oncogene. 2003;22:4186-4193.
-
(2003)
Oncogene
, vol.22
, pp. 4186-4193
-
-
Fajas, L.1
Egler, V.2
Reiter, R.3
Miard, S.4
Lefebvre, A.M.5
Auwerx, J.6
-
54
-
-
32544444894
-
Rosiglitazone inhibits endothelial proliferation and angiogenesis
-
Sheu WH, Ou HC, Chou FP, Lin TM, Yang CH. Rosiglitazone inhibits endothelial proliferation and angiogenesis. Life Sci. 2006;78:1520-1528.
-
(2006)
Life Sci
, vol.78
, pp. 1520-1528
-
-
Sheu, W.H.1
Ou, H.C.2
Chou, F.P.3
Lin, T.M.4
Yang, C.H.5
-
55
-
-
0032497832
-
Structure and function of phosphoinositide 3-kinases
-
Wymann MP, Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim Biophys Acta. 1998;1436:127-150.
-
(1998)
Biochim Biophys Acta
, vol.1436
, pp. 127-150
-
-
Wymann, M.P.1
Pirola, L.2
-
56
-
-
33747876794
-
The ERK1/2 pathway modulates nuclear PTENmediated cell cycle arrest by cyclin D1 transcriptional regulation
-
Chung JH, Ostrowski MC, Romigh T, Minaguchi T, Waite KA, Eng C. The ERK1/2 pathway modulates nuclear PTENmediated cell cycle arrest by cyclin D1 transcriptional regulation. Hum Mol Genet. 2006;15:2553-2559.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2553-2559
-
-
Chung, J.H.1
Ostrowski, M.C.2
Romigh, T.3
Minaguchi, T.4
Waite, K.A.5
Eng, C.6
-
57
-
-
0042971700
-
PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1
-
Radu A, Neubauer V, Akagi T, Hanafusa H, Georgescu MM. PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. Mol Cell Biol. 2003;23: 6139-6149.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6139-6149
-
-
Radu, A.1
Neubauer, V.2
Akagi, T.3
Hanafusa, H.4
Georgescu, M.M.5
-
58
-
-
4043050174
-
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/ p70S6K1 signaling in human ovarian cancer cells
-
Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/ p70S6K1 signaling in human ovarian cancer cells. Am J Physiol Cell Physiol. 2004;287:C281-C291.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Gao, N.1
Flynn, D.C.2
Zhang, Z.3
Zhong, X.S.4
Walker, V.5
Liu, K.J.6
Shi, X.7
Jiang, B.H.8
-
59
-
-
4644283083
-
Ability of the activated PI3K/Akt oncoprotein to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells
-
Shelton JG, Blalock WL, White ER, Steelman LS, McCubrey JA. Ability of the activated PI3K/Akt oncoprotein to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells. Cell Cycle. 2004;3:503-512.
-
(2004)
Cell Cycle
, vol.3
, pp. 503-512
-
-
Shelton, J.G.1
Blalock, W.L.2
White, E.R.3
Steelman, L.S.4
McCubrey, J.A.5
|