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Volumn 23, Issue 4, 2003, Pages 222-228

Troglitazone inhibits isolated cell proliferation, and induces apoptosis in isolated rat mesangial cells

Author keywords

Apoptosis; Cell proliferation; Mesangial cell; Mitogen activated protein kinase; Peroxyisome proliferator activated receptor gamma; Troglitazone

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BROXURIDINE; DNA FRAGMENT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; TROGLITAZONE;

EID: 0043074753     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000072053     Document Type: Article
Times cited : (24)

References (42)
  • 1
    • 0024817766 scopus 로고
    • The contribution of glomerular mesangial cells to progressive glomerulosclerosis
    • Striker LJ, Doi T, Elliot S, Striker GE: The contribution of glomerular mesangial cells to progressive glomerulosclerosis. Semin Nephrol 1989;9:318-328.
    • (1989) Semin Nephrol , vol.9 , pp. 318-328
    • Striker, L.J.1    Doi, T.2    Elliot, S.3    Striker, G.E.4
  • 2
    • 0024422014 scopus 로고
    • Mesangial expansion as a central mechanism for loss of kidney function in diabetic patients
    • Steffes MW, Osterby R, Chavers B, Mauer SM: Mesangial expansion as a central mechanism for loss of kidney function in diabetic patients. Diabetes 1989;38:1077-1081.
    • (1989) Diabetes , vol.38 , pp. 1077-1081
    • Steffes, M.W.1    Osterby, R.2    Chavers, B.3    Mauer, S.M.4
  • 3
    • 0026787630 scopus 로고
    • High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-beta
    • Wolf G, Sharma K, Chen Y, Ericksen M, Ziyadeh FN: High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-beta. Kidney Int 1992;42:647-656.
    • (1992) Kidney Int , vol.42 , pp. 647-656
    • Wolf, G.1    Sharma, K.2    Chen, Y.3    Ericksen, M.4    Ziyadeh, F.N.5
  • 6
    • 0028146675 scopus 로고
    • Translocation of protein kinase C alpha and zeta in rat glomerular mesangial cells cultured under high glucose conditions
    • Kikkawa R, Haneda M, Uzu T, Koya D, Sugimoto T, Shigeta Y: Translocation of protein kinase C alpha and zeta in rat glomerular mesangial cells cultured under high glucose conditions. Diabetologia 1994;37:838-841.
    • (1994) Diabetologia , vol.37 , pp. 838-841
    • Kikkawa, R.1    Haneda, M.2    Uzu, T.3    Koya, D.4    Sugimoto, T.5    Shigeta, Y.6
  • 7
    • 0030907294 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions
    • Haneda M, Arai S, Togawa M, Sugimoto T, Isono M, Kikkawa R: Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions. Diabetes 1997;46:847-853.
    • (1997) Diabetes , vol.46 , pp. 847-853
    • Haneda, M.1    Arai, S.2    Togawa, M.3    Sugimoto, T.4    Isono, M.5    Kikkawa, R.6
  • 8
    • 0031883161 scopus 로고    scopus 로고
    • Protein kinase C activation and its role in the development of vascular complication in diabetes mellitus
    • Ishii H, Koya D, King GL: Protein kinase C activation and its role in the development of vascular complication in diabetes mellitus. J Mol Med 1998;76:21-31.
    • (1998) J Mol Med , vol.76 , pp. 21-31
    • Ishii, H.1    Koya, D.2    King, G.L.3
  • 9
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complication
    • Koya D, King GL: Protein kinase C activation and the development of diabetic complication. Diabetes 1998;47:859-866.
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2
  • 11
    • 0024160854 scopus 로고
    • Characterization of new oral antidiabetic agent CS-045: Studies in KK and ob/ob mice and Zucker fatty rats
    • Fujiwara T, Yoshioka S, Yoshioka T, Ushiyama I, Horikoshi H: Characterization of new oral antidiabetic agent CS-045: Studies in KK and ob/ob mice and Zucker fatty rats. Diabetes 1988;37:1549-1558.
    • (1988) Diabetes , vol.37 , pp. 1549-1558
    • Fujiwara, T.1    Yoshioka, S.2    Yoshioka, T.3    Ushiyama, I.4    Horikoshi, H.5
  • 12
    • 0025938575 scopus 로고
    • Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice
    • Fujiwara T, Wada M, Fukuda K, Fukami M, Yoshioka S, Yoshioka T, Horikoshi H: Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice. Metabolism 1991;40:1213-1218.
    • (1991) Metabolism , vol.40 , pp. 1213-1218
    • Fujiwara, T.1    Wada, M.2    Fukuda, K.3    Fukami, M.4    Yoshioka, S.5    Yoshioka, T.6    Horikoshi, H.7
  • 13
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J: Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 1994;331:1188-1193.
    • (1994) N Engl J Med , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3    Joyce, M.4    Olefsky, J.5
  • 14
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkinson WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 1995;270:12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkinson, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 16
    • 0035098304 scopus 로고    scopus 로고
    • Expression and function of peroxisome proliferator-activated receptor-γ in mesangial cells
    • Nicholas SB, Kawano Y, Wakino S, Collins AR, Hsueh WA: Expression and function of peroxisome proliferator-activated receptor-γ in mesangial cells. Hyertension 2001;37:722-727.
    • (2001) Hyertension , vol.37 , pp. 722-727
    • Nicholas, S.B.1    Kawano, Y.2    Wakino, S.3    Collins, A.R.4    Hsueh, W.A.5
  • 18
    • 0034595727 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma 1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation
    • Asano T, Wakisaka M, Yoshinari M, Iino K, Sonoki K, Iwase M, Fujishima M: Peroxisome proliferator-activated receptor gamma 1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation. Biochm Biophys Acta 2000;1497:148-154.
    • (2000) Biochm Biophys Acta , vol.1497 , pp. 148-154
    • Asano, T.1    Wakisaka, M.2    Yoshinari, M.3    Iino, K.4    Sonoki, K.5    Iwase, M.6    Fujishima, M.7
  • 20
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytoxicity assays
    • Mosmann T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytoxicity assays. J Immunol Methods 1983;65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 21
    • 0022183360 scopus 로고
    • Quantification of 5-bromo-2-deoxyuridine incorporation into DNA: An enzyme immunoassay for the assessment of the lymphoid cell proliferative response
    • Porstmann T, Ternynck T, Avrameas S: Quantification of 5-bromo-2-deoxyuridine incorporation into DNA: An enzyme immunoassay for the assessment of the lymphoid cell proliferative response. J Immunol Methods 1985;82:169-179.
    • (1985) J Immunol Methods , vol.82 , pp. 169-179
    • Porstmann, T.1    Ternynck, T.2    Avrameas, S.3
  • 23
    • 0029781804 scopus 로고    scopus 로고
    • Induction of apoptosis by ubenimex (Bestatin®) in human non-small-cell lung cancer cell lines
    • Ezawa K, Minato K, Dobashi K: Induction of apoptosis by ubenimex (Bestatin®) in human non-small-cell lung cancer cell lines. Biomed Pharmacother 1996;50:283-289.
    • (1996) Biomed Pharmacother , vol.50 , pp. 283-289
    • Ezawa, K.1    Minato, K.2    Dobashi, K.3
  • 24
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:906-919.
    • (1993) Cell , vol.74 , pp. 906-919
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 26
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348:334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 27
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat
    • Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W: Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology 1996;137:354-366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 28
    • 0031847401 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker Fatty rats
    • Buckingham RE, Al-Barazanji KA, Toseland CD, Slaighter M, Connor SC, West A, Bond B, Turner NC, Clapham JC: Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker Fatty rats. Diabetes 1998;47:1326-1334.
    • (1998) Diabetes , vol.47 , pp. 1326-1334
    • Buckingham, R.E.1    Al-Barazanji, K.A.2    Toseland, C.D.3    Slaighter, M.4    Connor, S.C.5    West, A.6    Bond, B.7    Turner, N.C.8    Clapham, J.C.9
  • 29
    • 0033807476 scopus 로고    scopus 로고
    • Inflammation and microalbuminuria in nondiabetic and type 2 diabetic subjects: The Insulin Resistance Atherosclerosis study
    • Festa A, D'Agostino R, Howard G, Mykkanen L, Tracy RP, Haffner SM: Inflammation and microalbuminuria in nondiabetic and type 2 diabetic subjects: The Insulin Resistance Atherosclerosis Study. Kidney Int 2000;58:1703-1710.
    • (2000) Kidney Int , vol.58 , pp. 1703-1710
    • Festa, A.1    D'Agostino, R.2    Howard, G.3    Mykkanen, L.4    Tracy, R.P.5    Haffner, S.M.6
  • 30
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • Haffner SM, Greenberg AS, Weston WM, Chen H, Williams K, Freed MI: Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 2002;106:679-684.
    • (2002) Circulation , vol.106 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 31
    • 0001020521 scopus 로고
    • Phase I study of a new hypoglycemic agent CS-045 in healthy volunteers: Safety and pharmacokinetics in single administration
    • Shibata H, Nii S, Kobayashi M: Phase I study of a new hypoglycemic agent CS-045 in healthy volunteers: Safety and pharmacokinetics in single administration. Rinsho Iyaku 1993;9:1503-1518.
    • (1993) Rinsho Iyaku , vol.9 , pp. 1503-1518
    • Shibata, H.1    Nii, S.2    Kobayashi, M.3
  • 32
    • 0030979315 scopus 로고    scopus 로고
    • D-Glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: Implications for diabetic nephropathy
    • Heilig CW, Liu Y, England RL, Freytag SO, Gilbert JD, Heilig KO, Zhu M, Concepcion LA, Brosius FC 3rd: D-Glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: Implications for diabetic nephropathy. Diabetes 1997;46:1030-1039.
    • (1997) Diabetes , vol.46 , pp. 1030-1039
    • Heilig, C.W.1    Liu, Y.2    England, R.L.3    Freytag, S.O.4    Gilbert, J.D.5    Heilig, K.O.6    Zhu, M.7    Concepcion, L.A.8    Brosius F.C. III9
  • 33
    • 0034018619 scopus 로고    scopus 로고
    • Troglitazone enhances glycolysis and improves intracellular glucose metabolism in rat mesangial cells
    • Asano T, Wakisaka M, Yoshinari M, Nakamura S, Doi Y, Fujishima M: Troglitazone enhances glycolysis and improves intracellular glucose metabolism in rat mesangial cells. Metabolism 2000;49:308-313.
    • (2000) Metabolism , vol.49 , pp. 308-313
    • Asano, T.1    Wakisaka, M.2    Yoshinari, M.3    Nakamura, S.4    Doi, Y.5    Fujishima, M.6
  • 35
    • 0027218509 scopus 로고
    • Atrial natriuretic peptide inhibits endothelin-1-induced activation of mitogen-activated protein kinase in cultured rat mesangial cells
    • Sugimoto T, Kikkawa R, Haneda M, Shigeta Y: Atrial natriuretic peptide inhibits endothelin-1-induced activation of mitogen-activated protein kinase in cultured rat mesangial cells. Biochem Biophys Res Commun 1993;195:72-78.
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 72-78
    • Sugimoto, T.1    Kikkawa, R.2    Haneda, M.3    Shigeta, Y.4
  • 36
    • 0028811286 scopus 로고
    • Abnormalities in protein kinase C and MAP kinase cascade in mesangial cells cultured under high glucose conditions
    • Haneda M, Kikkawa R, Sugimoto T, Koya D, Araki S, Togawa M, Shigeta Y: Abnormalities in protein kinase C and MAP kinase cascade in mesangial cells cultured under high glucose conditions. J Diab Complications 1995;9:246-248.
    • (1995) J Diab Complications , vol.9 , pp. 246-248
    • Haneda, M.1    Kikkawa, R.2    Sugimoto, T.3    Koya, D.4    Araki, S.5    Togawa, M.6    Shigeta, Y.7
  • 37
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, Shintaku P, Said JW, Heber D, Koeffler HP: Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA 1998;95:8806-8811.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 38
    • 0032586875 scopus 로고    scopus 로고
    • Activation of PPAR gamma inhibits cell growth and induces apoptosis in human gastric cancer cells
    • Takahashi N, Okumura T, Motomura W, Fujimoto Y, Kawabata I, Kohgo Y: Activation of PPAR gamma inhibits cell growth and induces apoptosis in human gastric cancer cells. FEBS Lett 1999;455:135-139.
    • (1999) FEBS Lett , vol.455 , pp. 135-139
    • Takahashi, N.1    Okumura, T.2    Motomura, W.3    Fujimoto, Y.4    Kawabata, I.5    Kohgo, Y.6
  • 39
    • 0032696319 scopus 로고    scopus 로고
    • Thiazolidinedione induces apoptosis and monocytic differentiation in the promyelocytic leukemia cell line HL60
    • Hirase N, Yanase T, Mu Y, Muta K, Uemura T, Takayanagi R, Nawata H: Thiazolidinedione induces apoptosis and monocytic differentiation in the promyelocytic leukemia cell line HL60. Oncology 1999;57(suppl 2):17-26.
    • (1999) Oncology , vol.57 , Issue.SUPPL. 2 , pp. 17-26
    • Hirase, N.1    Yanase, T.2    Mu, Y.3    Muta, K.4    Uemura, T.5    Takayanagi, R.6    Nawata, H.7
  • 40
    • 85011526556 scopus 로고    scopus 로고
    • Troglitazone (CS-045) inhibits beta-cell proliferation rate following stimulation of insulin secretion in HIT-T 15 cells
    • Ohtani K, Shimizu H, Sato N, Mori M: Troglitazone (CS-045) inhibits beta-cell proliferation rate following stimulation of insulin secretion in HIT-T 15 cells. Endocrinology 1998;139:172-178.
    • (1998) Endocrinology , vol.139 , pp. 172-178
    • Ohtani, K.1    Shimizu, H.2    Sato, N.3    Mori, M.4


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