15-Deoxy-Δ12,14-prostaglandin J2 induces renal epithelial cell death through NF-κB-dependent and MAPK-independent mechanism

Toxicology and Applied Pharmacology

Volumn 216, Issue 3, 2006, Pages 426-435

  Kang, Dae Sik ^a   Kwon, Chae Hwa ^a   Park, Ji Yeon ^a   Kim, Jae Ho ^a   Woo, Jae Suk ^a   Jung, Jin Sup ^a   Kim, Yong Keun ^a  

^a Pusan National University School of Medicine   (South Korea)

Author keywords

Apoptosis; MAPK; NF B; Opossum kidney cells; PPAR ; ROS production

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 CHLORO 5 NITROBENZANILIDE; ACETYLCYSTEINE; CATALASE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; SYNAPTOTAGMIN; 15 DEOXY DELTA(12,14) PROSTAGLANDIN J2; 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J2; BISBENZIMIDE; DRUG DERIVATIVE; PROSTAGLANDIN D2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; NONHUMAN; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; KIDNEY; METABOLISM; OPOSSUM; PHYSIOLOGY; REPORTER GENE; WESTERN BLOTTING;

DIDELPHIDAE;

ANIMALS; APOPTOSIS; BISBENZIMIDE; BLOTTING, WESTERN; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPITHELIAL CELLS; FLOW CYTOMETRY; GENES, REPORTER; KIDNEY; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; OPOSSUMS; PROSTAGLANDIN D2; REACTIVE OXYGEN SPECIES; TRANSFECTION;

EID: 33750036728     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.06.008     Document Type: Article

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