메뉴 건너뛰기




Volumn 33, Issue 2, 2010, Pages 91-97

Biochemical properties of renin and prorenin binding to the (pro)renin receptor

Author keywords

'handle' region peptide; 'hinge' region peptide; (P)RR blocker; (pro)renin receptor; Decoy peptide

Indexed keywords

ALISKIREN; ANGIOTENSIN; HANDLE REGION PEPTIDE; HINGE REGION PEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PRORENIN; PRORENIN RECEPTOR; RENIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

EID: 76349117647     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2009.201     Document Type: Review
Times cited : (19)

References (70)
  • 1
    • 0021148216 scopus 로고
    • Cellular biology of the renin-angiotensin systems
    • Re RN. Cellular biology of the renin-angiotensin systems. Arch Intern Med 1984; 144: 2037-2041.
    • (1984) Arch Intern Med , vol.144 , pp. 2037-2041
    • Re, R.N.1
  • 2
    • 0024834343 scopus 로고
    • Clinical and physiologic significance of local tissue renin-angiotensin systems
    • Frohlich ED, Iwata T, Sasaki O. Clinical and physiologic significance of local tissue renin-angiotensin systems. Am J Med 1989; 87: 19s-22s.
    • (1989) Am J Med , vol.87
    • Frohlich, E.D.1    Iwata, T.2    Sasaki, O.3
  • 3
    • 0024651086 scopus 로고
    • Renin: Endocrine, paracrine, or part-paracrine control of blood pressure?
    • Lever AF. Renin: endocrine, paracrine, or part-paracrine control of blood pressure? Am J Hypertens 1989; 2: 276-285.
    • (1989) Am J Hypertens , vol.2 , pp. 276-285
    • Lever, A.F.1
  • 4
    • 0024653199 scopus 로고
    • Extrarenal renin and blood pressure regulation: An alternative viewpoint
    • Campbell DJ. Extrarenal renin and blood pressure regulation: an alternative viewpoint. Am J Hypertens 1989; 2: 266-275.
    • (1989) Am J Hypertens , vol.2 , pp. 266-275
    • Campbell, D.J.1
  • 5
    • 0042562091 scopus 로고
    • The endocrinology of hypertension
    • Felig P, Baxter JD, Frohman LA (eds) 3rd edn McGraw, McHill: New York
    • Baxter JD, Perloff D, Hsueh W, Biglieri EG. The endocrinology of hypertension. In: Felig P, Baxter JD, Frohman LA (eds). Endocrinology and Metabolism, 3rd edn McGraw, McHill: New York, 1995 pp 749-853.
    • (1995) Endocrinology and Metabolism , pp. 749-853
    • Baxter, J.D.1    Perloff, D.2    Hsueh, W.3    Biglieri, E.G.4
  • 6
    • 0028012543 scopus 로고
    • Renin is not synthesized by cardiac and extrarenal vascular tissues: A review of experimental evidence
    • Lutterotti NV, Catanzaro DF, Sealey JE, Laragh JH. Renin is not synthesized by cardiac and extrarenal vascular tissues: a review of experimental evidence. Circulation 1994; 89: 458-470.
    • (1994) Circulation , vol.89 , pp. 458-470
    • Lutterotti, N.V.1    Catanzaro, D.F.2    Sealey, J.E.3    Laragh, J.H.4
  • 7
    • 42649143024 scopus 로고    scopus 로고
    • Circulating versus tissue renin-angiotensin system: On the origin of (pro)renin
    • Krop M, Danser AH. Circulating versus tissue renin-angiotensin system: on the origin of (pro)renin. Curr Hypertens Rep 2008, 112-118.
    • (2008) Curr Hypertens Rep , pp. 112-118
    • Krop, M.1    Danser, A.H.2
  • 8
    • 0025786622 scopus 로고
    • Observations on the renal processing and sorting of prorenin
    • Hsueh WA, Do YS, Wang PH. Observations on the renal processing and sorting of prorenin. Can J Physiol Pharmacol 1991; 69: 1327-1330.
    • (1991) Can J Physiol Pharmacol , vol.69 , pp. 1327-1330
    • Hsueh, W.A.1    Do, Y.S.2    Wang, P.H.3
  • 10
    • 0021889169 scopus 로고
    • Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
    • Luetsher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications. N Engl J Med 1985; 312: 1412-1417.
    • (1985) N Engl J Med , vol.312 , pp. 1412-1417
    • Luetsher, J.A.1    Kraemer, F.B.2    Wilson, D.M.3    Schwartz, H.C.4    Bryer-Ash, M.5
  • 11
    • 0025913636 scopus 로고
    • Purification of renin and prorenin
    • Inagami T. Purification of renin and prorenin. Hypertension 1991; 18: 241-251.
    • (1991) Hypertension , vol.18 , pp. 241-251
    • Inagami, T.1
  • 12
    • 0026529572 scopus 로고
    • Molecular biology of renin I: Gene and protein structure, synthesis and processing
    • Morris BJ. Molecular biology of renin I: gene and protein structure, synthesis and processing. J Hypertens 1992; 10: 209-214.
    • (1992) J Hypertens , vol.10 , pp. 209-214
    • Morris, B.J.1
  • 13
    • 0029148866 scopus 로고
    • Acid-activation of rat prorenin following non-proteolytic alteration
    • Takahashi K (ed) Plenum Publishing Co.: New York
    • Suzuki F, Tanaka N, Takeuchi K, Muramoto Y, Inagami T, Murakami K, Nakamura Y. Acid-activation of rat prorenin following non-proteolytic alteration. In: Takahashi K (ed). Aspartic Proteinases. Plenum Publishing Co.: New York, 1995 pp 267-272.
    • (1995) Aspartic Proteinases , pp. 267-272
    • Suzuki, F.1    Tanaka, N.2    Takeuchi, K.3    Muramoto, Y.4    Inagami, T.5    Murakami, K.6    Nakamura, Y.7
  • 15
    • 0024603573 scopus 로고
    • A structural model to explain the partial catalytic activity of human prorenin
    • Heinrikson RL, Hui J, Zurcher-Neely H, Poorman RA. A structural model to explain the partial catalytic activity of human prorenin. Am J Hypertens 1989; 2: 367-380.
    • (1989) Am J Hypertens , vol.2 , pp. 367-380
    • Heinrikson, R.L.1    Hui, J.2    Zurcher-Neely, H.3    Poorman, R.A.4
  • 18
    • 0017804513 scopus 로고
    • Activation of human inactive ('Pro') renin by cathepsin D and pepsin
    • Morris BJ. Activation of human inactive ('Pro') renin by cathepsin D and pepsin. J Clin Endocrinol Metab 1978; 46: 153-157.
    • (1978) J Clin Endocrinol Metab , vol.46 , pp. 153-157
    • Morris, B.J.1
  • 19
    • 0023318520 scopus 로고
    • Human neutrophils release serine proteases capable of activating prorenin
    • Dzau VJ, Gonzalez D, Kaempfer C, Dubin D, Wintroub B. Human neutrophils release serine proteases capable of activating prorenin. Circ Res 1987; 60: 595-601.
    • (1987) Circ Res , vol.60 , pp. 595-601
    • Dzau, V.J.1    Gonzalez, D.2    Kaempfer, C.3    Dubin, D.4    Wintroub, B.5
  • 21
    • 0029907237 scopus 로고    scopus 로고
    • Prohormone convertase PC5 is a candidate processing enzyme for prorenin in the human adrenal cortex
    • Chantal M, Isabelle J, Robert D, Nabil GS, Timothy LR. Prohormone convertase PC5 is a candidate processing enzyme for prorenin in the human adrenal cortex. Hypertension 1996; 28: 840-846.
    • (1996) Hypertension , vol.28 , pp. 840-846
    • Chantal, M.1    Isabelle, J.2    Robert, D.3    Nabil, G.S.4    Timothy, L.R.5
  • 22
    • 0026529572 scopus 로고
    • Molecular biology of renin I: Gene and protein structure, synthesis and processing
    • Morris BJ. Molecular biology of renin I: gene and protein structure, synthesis and processing. J Hypertens 1992; 10: 209-214.
    • (1992) J Hypertens , vol.10 , pp. 209-214
    • Morris, B.J.1
  • 25
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/ prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T Sraer JD. Pivotal role of the renin/ prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 109: 1417-1427.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller Sraer T, J.D.5
  • 26
    • 33750600468 scopus 로고    scopus 로고
    • Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system
    • Nabi AHMN, Kageshima A, Uddin MN, Nakagawa T, Park EY, Suzuki F. Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 2006; 18: 483-488.
    • (2006) Int J Mol Med , vol.18 , pp. 483-488
    • Ahmn, N.1    Kageshima, A.2    Uddin, M.N.3    Nakagawa, T.4    Park, E.Y.5    Suzuki, F.6
  • 27
    • 35848948398 scopus 로고    scopus 로고
    • Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
    • Batenburg WW, Krop M, Garrelds IM, de Vries R, de Bruin RJ, Burcklé CA, Müller DN, Bader M, Nguyen G, Danser AH. Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens 2007; 25: 2441-2453.
    • (2007) J Hypertens , vol.25 , pp. 2441-2453
    • Batenburg, W.W.1    Krop, M.2    Garrelds, I.M.3    De Vries, R.4    De Bruin, R.J.5    Burcklé, C.A.6    Müller, D.N.7    Bader, M.8    Nguyen, G.9    Danser, A.H.10
  • 28
    • 56049114004 scopus 로고    scopus 로고
    • Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells
    • Zhang J, Noble NA, Border WA, Owens RT, Huang Y. Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 2008; 295: E810-E819.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Zhang, J.1    Noble, N.A.2    Border, W.A.3    Owens, R.T.4    Huang, Y.5
  • 29
    • 34547693066 scopus 로고    scopus 로고
    • Role of 'handle' region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor
    • Nurun NA, Uddin MN, Nakagawa T, Iwata H, Ichihara A, Inagami T, Suzuki F. Role of 'handle' region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor. Front Biosci 2007; 12: 4810-4817.
    • (2007) Front Biosci , vol.12 , pp. 4810-4817
    • Nurun, N.A.1    Uddin, M.N.2    Nakagawa, T.3    Iwata, H.4    Ichihara, A.5    Inagami, T.6    Suzuki, F.7
  • 33
    • 43449113857 scopus 로고    scopus 로고
    • Involvement of (pro)renin receptor in the glomerular filtration barrier
    • Ichihara A, Sakoda M, Kurauchi-Mito A, Kaneshiro Y, Itoh H. Involvement of (pro)renin receptor in the glomerular filtration barrier. J Mol Med 2008; 86: 629-635.
    • (2008) J Mol Med , vol.86 , pp. 629-635
    • Ichihara, A.1    Sakoda, M.2    Kurauchi-Mito, A.3    Kaneshiro, Y.4    Itoh, H.5
  • 37
    • 0030838008 scopus 로고    scopus 로고
    • Effect of bilateral nephrectomy on active renin, angiotensinogen, and renin glycoforms in plasma and myocardium
    • Katz SA, Opsahl JA, Lunzer MM, Forbis LM, Hirsch AT. Effect of bilateral nephrectomy on active renin, angiotensinogen, and renin glycoforms in plasma and myocardium. Hypertension 1997; 30: 259-266.
    • (1997) Hypertension , vol.30 , pp. 259-266
    • Katz, S.A.1    Opsahl, J.A.2    Lunzer, M.M.3    Forbis, L.M.4    Hirsch, A.T.5
  • 39
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • Huang Y, Wongamorntham S, Kasting J, McQuillan D, Owens RT, Yu L, Noble NA, Border W. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 2006; 69: 105-113.
    • (2006) Kidney Int , vol.69 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6    Noble, N.A.7    Border, W.8
  • 42
    • 33845608395 scopus 로고    scopus 로고
    • A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
    • Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 2006; 99: 1155-1166.
    • (2006) Circ Res , vol.99 , pp. 1155-1166
    • Schefe, J.H.1    Menk, M.2    Reinemund, J.3    Effertz, K.4    Hobbs, R.M.5    Pandolfi, P.P.6    Ruiz, P.7    Unger, T.8    Funke-Kaiser, H.9
  • 43
    • 34547988930 scopus 로고    scopus 로고
    • Non-proteolytic activation of prorenin by the (pro)renin receptor is blocked by decoy peptide
    • Suzuki F. Non-proteolytic activation of prorenin by the (pro)renin receptor is blocked by decoy peptide. J Renin Angiotensin Aldosterone Syst 2007; 8: 101-103.
    • (2007) J Renin Angiotensin Aldosterone Syst , vol.8 , pp. 101-103
    • Suzuki, F.1
  • 44
    • 67649534504 scopus 로고    scopus 로고
    • Decoy peptide region (RIFLKRMPSI) of prorenin prosegment plays a crucial role in prorenin binding to the (pro)renin receptor
    • Nabi AHMN, Biswas KB, Nakagawa T, Ichihara A, Inagami T, Suzuki F. Decoy peptide region (RIFLKRMPSI) of prorenin prosegment plays a crucial role in prorenin binding to the (pro)renin receptor. Int J Mol Med 2009; 24: 83-89.
    • (2009) Int J Mol Med , vol.24 , pp. 83-89
    • Ahmn, N.1    Biswas, K.B.2    Nakagawa, T.3    Ichihara, A.4    Inagami, T.5    Suzuki, F.6
  • 49
    • 42649086029 scopus 로고    scopus 로고
    • Characterization of a functional (pro)renin receptor in rat brain neurons
    • Shan Z, Cuadra AE, Sumners C, Raizada MK. Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol 2008; 93: 701-708.
    • (2008) Exp Physiol , vol.93 , pp. 701-708
    • Shan, Z.1    Cuadra, A.E.2    Sumners, C.3    Raizada, M.K.4
  • 50
    • 54049106595 scopus 로고    scopus 로고
    • Cardiovascular effects of prorenin blockade in genetically hypertensive rats (SHR) on normal and high salt diet
    • Susic D, Zhou X, Frohlich ED, Lippton H, Knight M. Cardiovascular effects of prorenin blockade in genetically hypertensive rats (SHR) on normal and high salt diet. Am J Physiol Heart circ Physiol 2008; 295: H1117-H1121.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Susic, D.1    Zhou, X.2    Frohlich, E.D.3    Lippton, H.4    Knight, M.5
  • 51
    • 60949099315 scopus 로고    scopus 로고
    • Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release
    • He M, Zhang L, Shao Y, Wang X, Huang Y, Yao T, Lu L. Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release. Eur J Pharmacol 2009; 606: 155-161.
    • (2009) Eur J Pharmacol , vol.606 , pp. 155-161
    • He, M.1    Zhang, L.2    Shao, Y.3    Wang, X.4    Huang, Y.5    Yao, T.6    Lu, L.7
  • 52
    • 76349107749 scopus 로고    scopus 로고
    • A peptide corresponding to handle region for nonproteolytic activation of prorenin inhibits retinal neovascularization in a retinopathy of prematurity model
    • E-Abstract 4108
    • Yokota H, Takamiya A, Nagaoka T, Kitaya N, Mori F, Hikichi T, Yoshida A, Ishida Y, Suzuki F. A peptide corresponding to handle region for nonproteolytic activation of prorenin inhibits retinal neovascularization in a retinopathy of prematurity model. Invest Ophthalmol Vis Sci 2005; 46 E-Abstract 4108.
    • (2005) Invest Ophthalmol Vis Sci , vol.46
    • Yokota, H.1    Takamiya, A.2    Nagaoka, T.3    Kitaya, N.4    Mori, F.5    Hikichi, T.6    Yoshida, A.7    Ishida, Y.8    Suzuki, F.9
  • 55
    • 39749088803 scopus 로고    scopus 로고
    • (Pro) renin receptor peptide inhibitor 'handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
    • Muller DN, Klanke B, Feldt S, Cordasic N, Hartner A, Schmieder RE, Luft FC, Hilgers KF. (Pro)renin receptor peptide inhibitor 'handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension 2008; 51: 676-681.
    • (2008) Hypertension , vol.51 , pp. 676-681
    • Muller, D.N.1    Klanke, B.2    Feldt, S.3    Cordasic, N.4    Hartner, A.5    Schmieder, R.E.6    Luft, F.C.7    Hilgers, K.F.8
  • 56
    • 67049100691 scopus 로고    scopus 로고
    • Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies
    • Mercure C, Prescott G, Lacombe MJ, Silversides DW, Reudelhuber TL. Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies. Hypertension 2009; 53: 1062-1069.
    • (2009) Hypertension , vol.53 , pp. 1062-1069
    • Mercure, C.1    Prescott, G.2    Lacombe, M.J.3    Silversides, D.W.4    Reudelhuber, T.L.5
  • 58
    • 42949109643 scopus 로고    scopus 로고
    • Aliskiren: The first renin inhibitor for clinical treatment
    • Jensen C, Herold P, Brunner HR. Aliskiren: the first renin inhibitor for clinical treatment. Nat Rev Drug Discov 2008; 7: 399-410.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 399-410
    • Jensen, C.1    Herold, P.2    Brunner, H.R.3
  • 59
    • 76349121230 scopus 로고    scopus 로고
    • Aliskiren and the kidney: Beyond hypertension
    • Trimarchi H, Orias M. Aliskiren and the kidney: beyond hypertension. Nephrol Rev 2009; 1: 1-4.
    • (2009) Nephrol Rev , vol.1 , pp. 1-4
    • Trimarchi, H.1    Orias, M.2
  • 63
    • 0018178966 scopus 로고
    • Inhibition of pepsin by zymogen activation fragments. Spectrum of peptides released from pepsino-gen NH2 terminus and solid phase synthesis of two inhibitory peptide sequences
    • Dunn BM, Deyrup C, Moesching WG, Gilbert WA, Nolan RJ, Trach ML. Inhibition of pepsin by zymogen activation fragments. Spectrum of peptides released from pepsino-gen NH2 terminus and solid phase synthesis of two inhibitory peptide sequences. J Biol Chem 1978; 253: 7269-7275.
    • (1978) J Biol Chem , vol.253 , pp. 7269-7275
    • Dunn, B.M.1    Deyrup, C.2    Moesching, W.G.3    Gilbert, W.A.4    Nolan, R.J.5    Trach, M.L.6
  • 64
    • 0016166825 scopus 로고
    • The activation of bovine pepsinogen. Sequence of the peptides released, identification of a pepsin inhibitor
    • Harboe M, Andersen PM, Foltman B, Kay J, Kassell B. The activation of bovine pepsinogen. Sequence of the peptides released, identification of a pepsin inhibitor. J Biol Chem 1974; 249: 4487-4494.
    • (1974) J Biol Chem , vol.249 , pp. 4487-4494
    • Harboe, M.1    Andersen, P.M.2    Foltman, B.3    Kay, J.4    Kassell, B.5
  • 67
    • 0019137579 scopus 로고
    • A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor
    • De Lean A, Stadel JM, Lefkowitz RJ. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. J Biol Chem 1980; 255: 7108-7117.
    • (1980) J Biol Chem , vol.255 , pp. 7108-7117
    • De Lean, A.1    Stadel, J.M.2    Lefkowitz, R.J.3
  • 68
    • 0031041454 scopus 로고    scopus 로고
    • 1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII
    • 1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII. J Cell Biol 1997; 272: 4245-4251.
    • (1997) J Cell Biol , vol.272 , pp. 4245-4251
    • Balmforth, A.J.1    Alj, L.2    Warburton, P.3    Donnelly, D.4    Ball, S.G.5
  • 70
    • 67049144916 scopus 로고    scopus 로고
    • Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma
    • Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G. Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension 2009; 53: 1077-1082.
    • (2009) Hypertension , vol.53 , pp. 1077-1082
    • Cousin, C.1    Bracquart, D.2    Contrepas, A.3    Corvol, P.4    Muller, L.5    Nguyen, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.