-
1
-
-
0021148216
-
Cellular biology of the renin-angiotensin systems
-
Re RN. Cellular biology of the renin-angiotensin systems. Arch Intern Med 1984; 144: 2037-2041.
-
(1984)
Arch Intern Med
, vol.144
, pp. 2037-2041
-
-
Re, R.N.1
-
2
-
-
0024834343
-
Clinical and physiologic significance of local tissue renin-angiotensin systems
-
Frohlich ED, Iwata T, Sasaki O. Clinical and physiologic significance of local tissue renin-angiotensin systems. Am J Med 1989; 87: 19s-22s.
-
(1989)
Am J Med
, vol.87
-
-
Frohlich, E.D.1
Iwata, T.2
Sasaki, O.3
-
3
-
-
0024651086
-
Renin: Endocrine, paracrine, or part-paracrine control of blood pressure?
-
Lever AF. Renin: endocrine, paracrine, or part-paracrine control of blood pressure? Am J Hypertens 1989; 2: 276-285.
-
(1989)
Am J Hypertens
, vol.2
, pp. 276-285
-
-
Lever, A.F.1
-
4
-
-
0024653199
-
Extrarenal renin and blood pressure regulation: An alternative viewpoint
-
Campbell DJ. Extrarenal renin and blood pressure regulation: an alternative viewpoint. Am J Hypertens 1989; 2: 266-275.
-
(1989)
Am J Hypertens
, vol.2
, pp. 266-275
-
-
Campbell, D.J.1
-
5
-
-
0042562091
-
The endocrinology of hypertension
-
Felig P, Baxter JD, Frohman LA (eds) 3rd edn McGraw, McHill: New York
-
Baxter JD, Perloff D, Hsueh W, Biglieri EG. The endocrinology of hypertension. In: Felig P, Baxter JD, Frohman LA (eds). Endocrinology and Metabolism, 3rd edn McGraw, McHill: New York, 1995 pp 749-853.
-
(1995)
Endocrinology and Metabolism
, pp. 749-853
-
-
Baxter, J.D.1
Perloff, D.2
Hsueh, W.3
Biglieri, E.G.4
-
6
-
-
0028012543
-
Renin is not synthesized by cardiac and extrarenal vascular tissues: A review of experimental evidence
-
Lutterotti NV, Catanzaro DF, Sealey JE, Laragh JH. Renin is not synthesized by cardiac and extrarenal vascular tissues: a review of experimental evidence. Circulation 1994; 89: 458-470.
-
(1994)
Circulation
, vol.89
, pp. 458-470
-
-
Lutterotti, N.V.1
Catanzaro, D.F.2
Sealey, J.E.3
Laragh, J.H.4
-
7
-
-
42649143024
-
Circulating versus tissue renin-angiotensin system: On the origin of (pro)renin
-
Krop M, Danser AH. Circulating versus tissue renin-angiotensin system: on the origin of (pro)renin. Curr Hypertens Rep 2008, 112-118.
-
(2008)
Curr Hypertens Rep
, pp. 112-118
-
-
Krop, M.1
Danser, A.H.2
-
8
-
-
0025786622
-
Observations on the renal processing and sorting of prorenin
-
Hsueh WA, Do YS, Wang PH. Observations on the renal processing and sorting of prorenin. Can J Physiol Pharmacol 1991; 69: 1327-1330.
-
(1991)
Can J Physiol Pharmacol
, vol.69
, pp. 1327-1330
-
-
Hsueh, W.A.1
Do, Y.S.2
Wang, P.H.3
-
10
-
-
0021889169
-
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
-
Luetsher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications. N Engl J Med 1985; 312: 1412-1417.
-
(1985)
N Engl J Med
, vol.312
, pp. 1412-1417
-
-
Luetsher, J.A.1
Kraemer, F.B.2
Wilson, D.M.3
Schwartz, H.C.4
Bryer-Ash, M.5
-
11
-
-
0025913636
-
Purification of renin and prorenin
-
Inagami T. Purification of renin and prorenin. Hypertension 1991; 18: 241-251.
-
(1991)
Hypertension
, vol.18
, pp. 241-251
-
-
Inagami, T.1
-
12
-
-
0026529572
-
Molecular biology of renin I: Gene and protein structure, synthesis and processing
-
Morris BJ. Molecular biology of renin I: gene and protein structure, synthesis and processing. J Hypertens 1992; 10: 209-214.
-
(1992)
J Hypertens
, vol.10
, pp. 209-214
-
-
Morris, B.J.1
-
13
-
-
0029148866
-
Acid-activation of rat prorenin following non-proteolytic alteration
-
Takahashi K (ed) Plenum Publishing Co.: New York
-
Suzuki F, Tanaka N, Takeuchi K, Muramoto Y, Inagami T, Murakami K, Nakamura Y. Acid-activation of rat prorenin following non-proteolytic alteration. In: Takahashi K (ed). Aspartic Proteinases. Plenum Publishing Co.: New York, 1995 pp 267-272.
-
(1995)
Aspartic Proteinases
, pp. 267-272
-
-
Suzuki, F.1
Tanaka, N.2
Takeuchi, K.3
Muramoto, Y.4
Inagami, T.5
Murakami, K.6
Nakamura, Y.7
-
14
-
-
0024952989
-
The molecular biology of human renin and its gene
-
Baxter JD, James MN, Chu WN, Duncan K, Haidar MA, Carilli CT, Reudelhuber TL. The molecular biology of human renin and its gene. Yale J Biol Med 1989; 62: 493-501.
-
(1989)
Yale J Biol Med
, vol.62
, pp. 493-501
-
-
Baxter, J.D.1
James, M.N.2
Chu, W.N.3
Duncan, K.4
Haidar, M.A.5
Carilli, C.T.6
Reudelhuber, T.L.7
-
15
-
-
0024603573
-
A structural model to explain the partial catalytic activity of human prorenin
-
Heinrikson RL, Hui J, Zurcher-Neely H, Poorman RA. A structural model to explain the partial catalytic activity of human prorenin. Am J Hypertens 1989; 2: 367-380.
-
(1989)
Am J Hypertens
, vol.2
, pp. 367-380
-
-
Heinrikson, R.L.1
Hui, J.2
Zurcher-Neely, H.3
Poorman, R.A.4
-
16
-
-
0023682895
-
Characterization of recombinant human prorenin and renin
-
Carilli CT, Vigne JL, Wallace LC, Smith LM, Wong MA, Lewicki JA, Baxter JD. Characterization of recombinant human prorenin and renin. Hypertension 1988; 11: 713-716.
-
(1988)
Hypertension
, vol.11
, pp. 713-716
-
-
Carilli, C.T.1
Vigne, J.L.2
Wallace, L.C.3
Smith, L.M.4
Wong, M.A.5
Lewicki, J.A.6
Baxter, J.D.7
-
17
-
-
0025779129
-
Identification of renal cathepsin B as a human prorenin-processing enzyme
-
Wang PH, Do YS, Macaulay L, Shinagawa T, Anderson PW, Baxter JD, Hsueh WA. Identification of renal cathepsin B as a human prorenin-processing enzyme. J Biol Chem 1991; 266: 12633-12638.
-
(1991)
J Biol Chem
, vol.266
, pp. 12633-12638
-
-
Wang, P.H.1
Do, Y.S.2
MacAulay, L.3
Shinagawa, T.4
Anderson, P.W.5
Baxter, J.D.6
Hsueh, W.A.7
-
18
-
-
0017804513
-
Activation of human inactive ('Pro') renin by cathepsin D and pepsin
-
Morris BJ. Activation of human inactive ('Pro') renin by cathepsin D and pepsin. J Clin Endocrinol Metab 1978; 46: 153-157.
-
(1978)
J Clin Endocrinol Metab
, vol.46
, pp. 153-157
-
-
Morris, B.J.1
-
19
-
-
0023318520
-
Human neutrophils release serine proteases capable of activating prorenin
-
Dzau VJ, Gonzalez D, Kaempfer C, Dubin D, Wintroub B. Human neutrophils release serine proteases capable of activating prorenin. Circ Res 1987; 60: 595-601.
-
(1987)
Circ Res
, vol.60
, pp. 595-601
-
-
Dzau, V.J.1
Gonzalez, D.2
Kaempfer, C.3
Dubin, D.4
Wintroub, B.5
-
20
-
-
0018600842
-
Activation of inactive plasma renin by tissue kallikreins
-
Derkx FHM, Tan-Tjiong L, Veld AJM, Schalekamp MPA, Schalekamp MADH. Activation of inactive plasma renin by tissue kallikreins. J Clin Endocrinol Metab 1979; 49: 765-769.
-
(1979)
J Clin Endocrinol Metab
, vol.49
, pp. 765-769
-
-
Derkx, F.H.M.1
Tan-Tjiong, L.2
Veld, A.J.M.3
Schalekamp, M.P.A.4
Schalekamp, M.A.D.H.5
-
21
-
-
0029907237
-
Prohormone convertase PC5 is a candidate processing enzyme for prorenin in the human adrenal cortex
-
Chantal M, Isabelle J, Robert D, Nabil GS, Timothy LR. Prohormone convertase PC5 is a candidate processing enzyme for prorenin in the human adrenal cortex. Hypertension 1996; 28: 840-846.
-
(1996)
Hypertension
, vol.28
, pp. 840-846
-
-
Chantal, M.1
Isabelle, J.2
Robert, D.3
Nabil, G.S.4
Timothy, L.R.5
-
22
-
-
0026529572
-
Molecular biology of renin I: Gene and protein structure, synthesis and processing
-
Morris BJ. Molecular biology of renin I: gene and protein structure, synthesis and processing. J Hypertens 1992; 10: 209-214.
-
(1992)
J Hypertens
, vol.10
, pp. 209-214
-
-
Morris, B.J.1
-
24
-
-
0037591344
-
Human prorenin has 'gate and handle' regions for its non-proteolytic activation
-
Suzuki F, Hayakawa M, Nakagawa T, Uddin MN, Ebihara A, Iwasawa A, Ishida Y, Nakamura Y, Kazuo M. Human prorenin has 'gate and handle' regions for its non-proteolytic activation. J Biol Chem 2003; 278: 22217-22222.
-
(2003)
J Biol Chem
, vol.278
, pp. 22217-22222
-
-
Suzuki, F.1
Hayakawa, M.2
Nakagawa, T.3
Uddin, M.N.4
Ebihara, A.5
Iwasawa, A.6
Ishida, Y.7
Nakamura, Y.8
Kazuo, M.9
-
25
-
-
0036266596
-
Pivotal role of the renin/ prorenin receptor in angiotensin II production and cellular responses to renin
-
Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T Sraer JD. Pivotal role of the renin/ prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 109: 1417-1427.
-
(2002)
J Clin Invest
, vol.109
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burckle, C.3
Bouzhir, L.4
Giller Sraer T, J.D.5
-
26
-
-
33750600468
-
Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system
-
Nabi AHMN, Kageshima A, Uddin MN, Nakagawa T, Park EY, Suzuki F. Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 2006; 18: 483-488.
-
(2006)
Int J Mol Med
, vol.18
, pp. 483-488
-
-
Ahmn, N.1
Kageshima, A.2
Uddin, M.N.3
Nakagawa, T.4
Park, E.Y.5
Suzuki, F.6
-
27
-
-
35848948398
-
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
-
Batenburg WW, Krop M, Garrelds IM, de Vries R, de Bruin RJ, Burcklé CA, Müller DN, Bader M, Nguyen G, Danser AH. Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens 2007; 25: 2441-2453.
-
(2007)
J Hypertens
, vol.25
, pp. 2441-2453
-
-
Batenburg, W.W.1
Krop, M.2
Garrelds, I.M.3
De Vries, R.4
De Bruin, R.J.5
Burcklé, C.A.6
Müller, D.N.7
Bader, M.8
Nguyen, G.9
Danser, A.H.10
-
28
-
-
56049114004
-
Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells
-
Zhang J, Noble NA, Border WA, Owens RT, Huang Y. Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 2008; 295: E810-E819.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Zhang, J.1
Noble, N.A.2
Border, W.A.3
Owens, R.T.4
Huang, Y.5
-
29
-
-
34547693066
-
Role of 'handle' region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor
-
Nurun NA, Uddin MN, Nakagawa T, Iwata H, Ichihara A, Inagami T, Suzuki F. Role of 'handle' region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor. Front Biosci 2007; 12: 4810-4817.
-
(2007)
Front Biosci
, vol.12
, pp. 4810-4817
-
-
Nurun, N.A.1
Uddin, M.N.2
Nakagawa, T.3
Iwata, H.4
Ichihara, A.5
Inagami, T.6
Suzuki, F.7
-
30
-
-
9644283069
-
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the 'handle' region for nonproteolytic activation of prorenin
-
Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, Koura Y, Nishiyama A, Okada H, Uddin MN, Nabi AHMN, Ishida Y, Inagami T, Saruta T. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the 'handle' region for nonproteolytic activation of prorenin. J Clin Invest 2004; 114: 1128-1135.
-
(2004)
J Clin Invest
, vol.114
, pp. 1128-1135
-
-
Ichihara, A.1
Hayashi, M.2
Kaneshiro, Y.3
Suzuki, F.4
Nakagawa, T.5
Tada, Y.6
Koura, Y.7
Nishiyama, A.8
Okada, H.9
Uddin, M.N.10
Ahmn, N.11
Ishida, Y.12
Inagami, T.13
Saruta, T.14
-
31
-
-
34249881320
-
Slowly progressive, angiotensin II-indepen-dent glomerulosclerosis in human renin/prorenin receptor transgenic rats
-
Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AN, Uddin MN, Nakagawa T, Nishiyama A, Suzuki F, Inagami T, Itoh H. Slowly progressive, angiotensin II-indepen-dent glomerulosclerosis in human renin/prorenin receptor transgenic rats. J Am Soc Nephrol 2007; 18: 1789-1795.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1789-1795
-
-
Kaneshiro, Y.1
Ichihara, A.2
Sakoda, M.3
Takemitsu, T.4
Nabi, A.N.5
Uddin, M.N.6
Nakagawa, T.7
Nishiyama, A.8
Suzuki, F.9
Inagami, T.10
Itoh, H.11
-
32
-
-
33644983896
-
Elevated blood pressure and heart rate in human renin receptor transgenic rats
-
Burckle CA, Jan Danser AH, Muller DN, Garrelds IM, Gasc JM, Popova E, Plehm R, Peters J, Bader M, Nguyen G. Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 2006; 47: 1-5.
-
(2006)
Hypertension
, vol.47
, pp. 1-5
-
-
Burckle, C.A.1
Jan Danser, A.H.2
Muller, D.N.3
Garrelds, I.M.4
Gasc, J.M.5
Popova, E.6
Plehm, R.7
Peters, J.8
Bader, M.9
Nguyen, G.10
-
33
-
-
43449113857
-
Involvement of (pro)renin receptor in the glomerular filtration barrier
-
Ichihara A, Sakoda M, Kurauchi-Mito A, Kaneshiro Y, Itoh H. Involvement of (pro)renin receptor in the glomerular filtration barrier. J Mol Med 2008; 86: 629-635.
-
(2008)
J Mol Med
, vol.86
, pp. 629-635
-
-
Ichihara, A.1
Sakoda, M.2
Kurauchi-Mito, A.3
Kaneshiro, Y.4
Itoh, H.5
-
35
-
-
69449099438
-
Renin, prorenin and the kidney: A new chapter in an old saga
-
Ichihara A, Sakoda M, Kurauchi-Mito A, Kaneshiro Y, Itoh H. Renin, prorenin and the kidney: a new chapter in an old saga. J Nephrol 2009; 22: 306-311.
-
(2009)
J Nephrol
, vol.22
, pp. 306-311
-
-
Ichihara, A.1
Sakoda, M.2
Kurauchi-Mito, A.3
Kaneshiro, Y.4
Itoh, H.5
-
36
-
-
0028229413
-
Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis
-
Danser AHJ, van Kats JP, Admiraal PJJ, Derkx FHM, Lamers JMJ, Verdouw PD, Saxena PR, Schalekamp MADH. Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis. Hypertension 1994; 24: 37-48.
-
(1994)
Hypertension
, vol.24
, pp. 37-48
-
-
Danser, A.H.J.1
Van Kats, J.P.2
Admiraal, P.J.J.3
Derkx, F.H.M.4
Lamers, J.M.J.5
Verdouw, P.D.6
Saxena, P.R.7
Schalekamp, M.A.D.H.8
-
37
-
-
0030838008
-
Effect of bilateral nephrectomy on active renin, angiotensinogen, and renin glycoforms in plasma and myocardium
-
Katz SA, Opsahl JA, Lunzer MM, Forbis LM, Hirsch AT. Effect of bilateral nephrectomy on active renin, angiotensinogen, and renin glycoforms in plasma and myocardium. Hypertension 1997; 30: 259-266.
-
(1997)
Hypertension
, vol.30
, pp. 259-266
-
-
Katz, S.A.1
Opsahl, J.A.2
Lunzer, M.M.3
Forbis, L.M.4
Hirsch, A.T.5
-
38
-
-
39749098706
-
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
-
Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burckle C, Contrepas A, Danser AHJ, Bader M, Nguyen G, Luft FC, Muller DN. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 2008; 51: 682-688.
-
(2008)
Hypertension
, vol.51
, pp. 682-688
-
-
Feldt, S.1
Batenburg, W.W.2
Mazak, I.3
Maschke, U.4
Wellner, M.5
Kvakan, H.6
Dechend, R.7
Fiebeler, A.8
Burckle, C.9
Contrepas, A.10
Danser, A.H.J.11
Bader, M.12
Nguyen, G.13
Luft, F.C.14
Muller, D.N.15
-
39
-
-
30944469631
-
Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
-
Huang Y, Wongamorntham S, Kasting J, McQuillan D, Owens RT, Yu L, Noble NA, Border W. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 2006; 69: 105-113.
-
(2006)
Kidney Int
, vol.69
, pp. 105-113
-
-
Huang, Y.1
Wongamorntham, S.2
Kasting, J.3
McQuillan, D.4
Owens, R.T.5
Yu, L.6
Noble, N.A.7
Border, W.8
-
40
-
-
33750266798
-
Prorenin induces intracellular signalling in cardiomyocytes independently of angiotensin II
-
Saris JJ, t Hoen PA, Garrelds IM, Dekkers DH, den Dunnen JT, Lamers JM, Jan Danser AH. Prorenin induces intracellular signalling in cardiomyocytes independently of angiotensin II. Hypertension 2006; 48: 564-571.
-
(2006)
Hypertension
, vol.48
, pp. 564-571
-
-
Saris, J.J.1
Hoen P A, T.2
Garrelds, I.M.3
Dekkers, D.H.4
Den Dunnen, J.T.5
Lamers, J.M.6
Jan Danser, A.H.7
-
41
-
-
37849044605
-
(Pro) renin receptor-mediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells
-
Sakoda M, Ichihara A, Kaneshiro Y, Takemitsu T, Nakazato Y, Nabi AH, Nakagawa T, Suzuki F, Inagami T, Itoh H. (Pro)renin receptor-mediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells. Hypertens Res 2007; 30: 1139-1146.
-
(2007)
Hypertens Res
, vol.30
, pp. 1139-1146
-
-
Sakoda, M.1
Ichihara, A.2
Kaneshiro, Y.3
Takemitsu, T.4
Nakazato, Y.5
Nabi, A.H.6
Nakagawa, T.7
Suzuki, F.8
Inagami, T.9
Itoh, H.10
-
42
-
-
33845608395
-
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
-
Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 2006; 99: 1155-1166.
-
(2006)
Circ Res
, vol.99
, pp. 1155-1166
-
-
Schefe, J.H.1
Menk, M.2
Reinemund, J.3
Effertz, K.4
Hobbs, R.M.5
Pandolfi, P.P.6
Ruiz, P.7
Unger, T.8
Funke-Kaiser, H.9
-
43
-
-
34547988930
-
Non-proteolytic activation of prorenin by the (pro)renin receptor is blocked by decoy peptide
-
Suzuki F. Non-proteolytic activation of prorenin by the (pro)renin receptor is blocked by decoy peptide. J Renin Angiotensin Aldosterone Syst 2007; 8: 101-103.
-
(2007)
J Renin Angiotensin Aldosterone Syst
, vol.8
, pp. 101-103
-
-
Suzuki, F.1
-
44
-
-
67649534504
-
Decoy peptide region (RIFLKRMPSI) of prorenin prosegment plays a crucial role in prorenin binding to the (pro)renin receptor
-
Nabi AHMN, Biswas KB, Nakagawa T, Ichihara A, Inagami T, Suzuki F. Decoy peptide region (RIFLKRMPSI) of prorenin prosegment plays a crucial role in prorenin binding to the (pro)renin receptor. Int J Mol Med 2009; 24: 83-89.
-
(2009)
Int J Mol Med
, vol.24
, pp. 83-89
-
-
Ahmn, N.1
Biswas, K.B.2
Nakagawa, T.3
Ichihara, A.4
Inagami, T.5
Suzuki, F.6
-
45
-
-
73049099445
-
Prorenin has high affinity multiple binding sites for (pro)renin receptor
-
Nabi AHMN, Biswas KB, Nakagawa T, Ichihara A, Inagami T, Suzuki F. Prorenin has high affinity multiple binding sites for (pro)renin receptor. Biochim Biophys Acta 2009; 1794: 1838-1847.
-
(2009)
Biochim Biophys Acta
, vol.1794
, pp. 1838-1847
-
-
Ahmn, N.1
Biswas, K.B.2
Nakagawa, T.3
Ichihara, A.4
Inagami, T.5
Suzuki, F.6
-
46
-
-
34447272037
-
Regression of nephropathy developed in diabetes by (Pro)renin receptor blockade
-
Takahashi H, Ichihara A, Kaneshiro Y, Inomata K, Sakoda M, Takemitsu T, Nishiyama A, Itoh H. Regression of nephropathy developed in diabetes by (Pro)renin receptor blockade. J Am Soc Nephrol 2007; 18: 2054-2061.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2054-2061
-
-
Takahashi, H.1
Ichihara, A.2
Kaneshiro, Y.3
Inomata, K.4
Sakoda, M.5
Takemitsu, T.6
Nishiyama, A.7
Itoh, H.8
-
47
-
-
33748044643
-
Contribution of non-proteolytically activated prorenin in glomeruli to hypertensive renal damage
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Nakagawa T, Nishiyama A, Kawachi H, Shimizu F, Inagami T. Contribution of non-proteolytically activated prorenin in glomeruli to hypertensive renal damage. J Am Soc Nephrol 2006; 17: 2495-2503.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2495-2503
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Nakagawa, T.5
Nishiyama, A.6
Kawachi, H.7
Shimizu, F.8
Inagami, T.9
-
48
-
-
33646160993
-
Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, Nishiyama A, Inagami T, Hayashi M. Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 2006; 47: 894-900.
-
(2006)
Hypertension
, vol.47
, pp. 894-900
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
Nakagawa, T.6
Nishiyama, A.7
Inagami, T.8
Hayashi, M.9
-
49
-
-
42649086029
-
Characterization of a functional (pro)renin receptor in rat brain neurons
-
Shan Z, Cuadra AE, Sumners C, Raizada MK. Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol 2008; 93: 701-708.
-
(2008)
Exp Physiol
, vol.93
, pp. 701-708
-
-
Shan, Z.1
Cuadra, A.E.2
Sumners, C.3
Raizada, M.K.4
-
50
-
-
54049106595
-
Cardiovascular effects of prorenin blockade in genetically hypertensive rats (SHR) on normal and high salt diet
-
Susic D, Zhou X, Frohlich ED, Lippton H, Knight M. Cardiovascular effects of prorenin blockade in genetically hypertensive rats (SHR) on normal and high salt diet. Am J Physiol Heart circ Physiol 2008; 295: H1117-H1121.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Susic, D.1
Zhou, X.2
Frohlich, E.D.3
Lippton, H.4
Knight, M.5
-
51
-
-
60949099315
-
Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release
-
He M, Zhang L, Shao Y, Wang X, Huang Y, Yao T, Lu L. Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release. Eur J Pharmacol 2009; 606: 155-161.
-
(2009)
Eur J Pharmacol
, vol.606
, pp. 155-161
-
-
He, M.1
Zhang, L.2
Shao, Y.3
Wang, X.4
Huang, Y.5
Yao, T.6
Lu, L.7
-
52
-
-
76349107749
-
A peptide corresponding to handle region for nonproteolytic activation of prorenin inhibits retinal neovascularization in a retinopathy of prematurity model
-
E-Abstract 4108
-
Yokota H, Takamiya A, Nagaoka T, Kitaya N, Mori F, Hikichi T, Yoshida A, Ishida Y, Suzuki F. A peptide corresponding to handle region for nonproteolytic activation of prorenin inhibits retinal neovascularization in a retinopathy of prematurity model. Invest Ophthalmol Vis Sci 2005; 46 E-Abstract 4108.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
-
-
Yokota, H.1
Takamiya, A.2
Nagaoka, T.3
Kitaya, N.4
Mori, F.5
Hikichi, T.6
Yoshida, A.7
Ishida, Y.8
Suzuki, F.9
-
53
-
-
33846902147
-
Role of nonproteolytically activated prorenin in pathologic, but not physiologic, retinal neovascularization
-
Satofuka S, Ichihara A, Nagai N, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Itoh H, Oike Y, Ishida S. Role of nonproteolytically activated prorenin in pathologic, but not physiologic, retinal neovascularization. Invest Ophthalmol Vis Sci 2007; 48: 422-429.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 422-429
-
-
Satofuka, S.1
Ichihara, A.2
Nagai, N.3
Koto, T.4
Shinoda, H.5
Noda, K.6
Ozawa, Y.7
Inoue, M.8
Tsubota, K.9
Itoh, H.10
Oike, Y.11
Ishida, S.12
-
54
-
-
33745674108
-
Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin
-
Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Suzuki F, Oike Y, Ishida S. Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin. Invest Ophthalmol Vis Sci 2006; 47: 2686-2692.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 2686-2692
-
-
Satofuka, S.1
Ichihara, A.2
Nagai, N.3
Yamashiro, K.4
Koto, T.5
Shinoda, H.6
Noda, K.7
Ozawa, Y.8
Inoue, M.9
Tsubota, K.10
Suzuki, F.11
Oike, Y.12
Ishida, S.13
-
55
-
-
39749088803
-
(Pro) renin receptor peptide inhibitor 'handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
-
Muller DN, Klanke B, Feldt S, Cordasic N, Hartner A, Schmieder RE, Luft FC, Hilgers KF. (Pro)renin receptor peptide inhibitor 'handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension 2008; 51: 676-681.
-
(2008)
Hypertension
, vol.51
, pp. 676-681
-
-
Muller, D.N.1
Klanke, B.2
Feldt, S.3
Cordasic, N.4
Hartner, A.5
Schmieder, R.E.6
Luft, F.C.7
Hilgers, K.F.8
-
56
-
-
67049100691
-
Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies
-
Mercure C, Prescott G, Lacombe MJ, Silversides DW, Reudelhuber TL. Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies. Hypertension 2009; 53: 1062-1069.
-
(2009)
Hypertension
, vol.53
, pp. 1062-1069
-
-
Mercure, C.1
Prescott, G.2
Lacombe, M.J.3
Silversides, D.W.4
Reudelhuber, T.L.5
-
57
-
-
0042661157
-
Structure-based design of aliskiren, a novel orally effective renin inhibitor
-
Wood JM, Maibaum J, Rahuel J, Grütter MG, Cohen NC, Rasetti V, Rüger H, Göschke R, Stutz S, Fuhrer W, Schilling W, Rigollier P, Yamaguchi Y, Cumin F, Baum HP, Schnell CR, Herold P, Mah R, Jensen C, O'Brien E, Stanton A, Bedigian MP. Structure-based design of aliskiren, a novel orally effective renin inhibitor. Biochem Biophys Res Commun 2003; 308: 698-705.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 698-705
-
-
Wood, J.M.1
Maibaum, J.2
Rahuel, J.3
Grütter, M.G.4
Cohen, N.C.5
Rasetti, V.6
Rüger, H.7
Göschke, R.8
Stutz, S.9
Fuhrer, W.10
Schilling, W.11
Rigollier, P.12
Yamaguchi, Y.13
Cumin, F.14
Baum, H.P.15
Schnell, C.R.16
Herold, P.17
Mah, R.18
Jensen, C.19
O'Brien, E.20
Stanton, A.21
Bedigian, M.P.22
more..
-
58
-
-
42949109643
-
Aliskiren: The first renin inhibitor for clinical treatment
-
Jensen C, Herold P, Brunner HR. Aliskiren: the first renin inhibitor for clinical treatment. Nat Rev Drug Discov 2008; 7: 399-410.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 399-410
-
-
Jensen, C.1
Herold, P.2
Brunner, H.R.3
-
59
-
-
76349121230
-
Aliskiren and the kidney: Beyond hypertension
-
Trimarchi H, Orias M. Aliskiren and the kidney: beyond hypertension. Nephrol Rev 2009; 1: 1-4.
-
(2009)
Nephrol Rev
, vol.1
, pp. 1-4
-
-
Trimarchi, H.1
Orias, M.2
-
60
-
-
57449100853
-
Aliskiren accumulates in renin secretory granules and binds plasma prorenin
-
Krop M, Garrelds IM, de Bruin RJA, van Gool JMG, Fisher NDL, Hollenberg NK, Danser AHJ. Aliskiren accumulates in renin secretory granules and binds plasma prorenin. Hypertension 2008; 52: 1076-1083.
-
(2008)
Hypertension
, vol.52
, pp. 1076-1083
-
-
Krop, M.1
Garrelds, I.M.2
De Bruin, R.J.A.3
Van Gool, J.M.G.4
Fisher, N.D.L.5
Hollenberg, N.K.6
Danser, A.H.J.7
-
61
-
-
46449118638
-
Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
-
Feldman DL, Jin L, Xuan H, Contrepas A, Zhou Y, Webb RL, Mueller DN, Feldt S, Cumin F, Maniara W, Persohn E, Schuetz H, Jan Danser AH, Nguyen G. Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 2008; 52: 130-136.
-
(2008)
Hypertension
, vol.52
, pp. 130-136
-
-
Feldman, D.L.1
Jin, L.2
Xuan, H.3
Contrepas, A.4
Zhou, Y.5
Webb, R.L.6
Mueller, D.N.7
Feldt, S.8
Cumin, F.9
Maniara, W.10
Persohn, E.11
Schuetz, H.12
Jan Danser, A.H.13
Nguyen, G.14
-
62
-
-
0019958486
-
Potent new inhibitors of human renin
-
Szelke M, Leckie B, Hallett A, Jones DM, Sueiras J, Atrash B, Lever AF. Potent new inhibitors of human renin. Nature 1982; 299: 555-557.
-
(1982)
Nature
, vol.299
, pp. 555-557
-
-
Szelke, M.1
Leckie, B.2
Hallett, A.3
Jones, D.M.4
Sueiras, J.5
Atrash, B.6
Lever, A.F.7
-
63
-
-
0018178966
-
Inhibition of pepsin by zymogen activation fragments. Spectrum of peptides released from pepsino-gen NH2 terminus and solid phase synthesis of two inhibitory peptide sequences
-
Dunn BM, Deyrup C, Moesching WG, Gilbert WA, Nolan RJ, Trach ML. Inhibition of pepsin by zymogen activation fragments. Spectrum of peptides released from pepsino-gen NH2 terminus and solid phase synthesis of two inhibitory peptide sequences. J Biol Chem 1978; 253: 7269-7275.
-
(1978)
J Biol Chem
, vol.253
, pp. 7269-7275
-
-
Dunn, B.M.1
Deyrup, C.2
Moesching, W.G.3
Gilbert, W.A.4
Nolan, R.J.5
Trach, M.L.6
-
64
-
-
0016166825
-
The activation of bovine pepsinogen. Sequence of the peptides released, identification of a pepsin inhibitor
-
Harboe M, Andersen PM, Foltman B, Kay J, Kassell B. The activation of bovine pepsinogen. Sequence of the peptides released, identification of a pepsin inhibitor. J Biol Chem 1974; 249: 4487-4494.
-
(1974)
J Biol Chem
, vol.249
, pp. 4487-4494
-
-
Harboe, M.1
Andersen, P.M.2
Foltman, B.3
Kay, J.4
Kassell, B.5
-
65
-
-
0022253247
-
Inhibition of human renin by synthetic peptides derived from its prosegment
-
Cumin F, Evin G, Fehrentz JA, Seyer R, Castro B, Menard I, Corvol P. Inhibition of human renin by synthetic peptides derived from its prosegment. J Biol Chem 1985; 260: 9154-9157.
-
(1985)
J Biol Chem
, vol.260
, pp. 9154-9157
-
-
Cumin, F.1
Evin, G.2
Fehrentz, J.A.3
Seyer, R.4
Castro, B.5
Menard, I.6
Corvol, P.7
-
66
-
-
2642544810
-
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER a and ER b
-
Paige LA, Christensen DJ, Grøn H, Norris JD, Gottlin EB, Padilla KM, Chang C, Ballas LM, Hamilton PT, Mcdonnell DP, Fowlkes D. Estrogen receptor (ER) modulators each induce distinct conformational changes in ER a and ER b. Proc Natl Acad Sci USA 1999; 96: 3999-4004.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3999-4004
-
-
Paige, L.A.1
Christensen, D.J.2
Grøn, H.3
Norris, J.D.4
Gottlin, E.B.5
Padilla, K.M.6
Chang, C.7
Ballas, L.M.8
Hamilton, P.T.9
McDonnell, D.P.10
Fowlkes, D.11
-
67
-
-
0019137579
-
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor
-
De Lean A, Stadel JM, Lefkowitz RJ. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. J Biol Chem 1980; 255: 7108-7117.
-
(1980)
J Biol Chem
, vol.255
, pp. 7108-7117
-
-
De Lean, A.1
Stadel, J.M.2
Lefkowitz, R.J.3
-
68
-
-
0031041454
-
1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII
-
1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII. J Cell Biol 1997; 272: 4245-4251.
-
(1997)
J Cell Biol
, vol.272
, pp. 4245-4251
-
-
Balmforth, A.J.1
Alj, L.2
Warburton, P.3
Donnelly, D.4
Ball, S.G.5
-
69
-
-
13444274458
-
Regulation of a5b1 integrin conformation and function by urokinase receptor binding
-
Wei Y, Czekay RP, Robillard L, Kugler MC, Zhang F, Kim KK, Xiong J, Humphries MJ, Chapman HA. Regulation of a5b1 integrin conformation and function by urokinase receptor binding. J Cell Biol 2005; 168: 501-511.
-
(2005)
J Cell Biol
, vol.168
, pp. 501-511
-
-
Wei, Y.1
Czekay, R.P.2
Robillard, L.3
Kugler, M.C.4
Zhang, F.5
Kim, K.K.6
Xiong, J.7
Humphries, M.J.8
Chapman, H.A.9
-
70
-
-
67049144916
-
Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma
-
Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G. Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension 2009; 53: 1077-1082.
-
(2009)
Hypertension
, vol.53
, pp. 1077-1082
-
-
Cousin, C.1
Bracquart, D.2
Contrepas, A.3
Corvol, P.4
Muller, L.5
Nguyen, G.6
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