Effects of the very late adhesion molecule 4 antagonist WAY103 on human peripheral blood eosinophil vascular cell adhesion molecule 1-dependent functions

Journal of Allergy and Clinical Immunology

Volumn 116, Issue 4, 2005, Pages 812-819

  Sedgwick, Julie B ^a,d   Jansen, Kristyn J ^a   Kennedy, Jeffrey D ^b   Kita, Hirohito ^c   Busse, William W ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b PFIZER INC   (United States)

^c MAYO CLINIC   (United States)

^d CSC 3244 H6/355 ^*  (United States)

Author keywords

Adhesion; Degranulation; Endothelial cells; Eosinophil; Respiratory burst; Transendothelial migration; Vascular cell adhesion molecule 1; Very late adhesion molecule 4 antagonists

Indexed keywords

3 (4 DIMETHYLCARBAMOYLOXYPHENYL) 2 [[5,5 DIMETHYL 3 (1 METHYL 1H PYRAZOLE 4 SULFONYL)THIAZOLIDINE 4 CARBONYL]AMINO]PROPIONIC ACID; ANTIINFLAMMATORY AGENT; BETA2 INTEGRIN; CYTOCHROME C; INTERLEUKIN 4; MONOCLONAL ANTIBODY; NEUROTOXIN; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; WAY 103;

ARTICLE; CELL ADHESION; CELL MIGRATION; COMPARATIVE STUDY; CONTROLLED STUDY; DEGRANULATION; ENDOTHELIUM CELL; EOSINOPHIL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; RESPIRATORY BURST;

ADOLESCENT; ADULT; CELL ADHESION; CELL DEGRANULATION; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; EOSINOPHIL-DERIVED NEUROTOXIN; EOSINOPHILS; FEMALE; HUMANS; INTEGRIN ALPHA4BETA1; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; PYRAZOLES; SUPEROXIDES; THIAZOLES; THIAZOLIDINES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 25844439944     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2005.07.003     Document Type: Article

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