Regulation of T helper type 2 cell differentiation by murine Schnurri-2

Journal of Experimental Medicine

Volumn 201, Issue 3, 2005, Pages 397-408

  Kimura, Motoko Y ^a   Hosokawa, Hiroyuki ^a   Yamashita, Masakatsu ^a   Hasegawa, Akihiro ^a   Iwamura, Chiaki ^a   Watarai, Hiroshi ^a   Taniguchi, Masaru ^b   Takagi, Tsuyoshi ^c   Ishii, Shunsuke ^c   Nakayama, Toshinori ^a  

^a CHIBA UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c RIKEN TSUKUBA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; PROTEIN SCHNURRI 1; PROTEIN SCHNURRI 2; PROTEIN SCHNURRI 3; T LYMPHOCYTE ANTIBODY; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; HELPER CELL; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INDUCTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; TH1 CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; DNA-BINDING PROTEINS; GATA3 TRANSCRIPTION FACTOR; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, TRANSGENIC; NF-KAPPA B; PHENOTYPE; PROTEIN ISOFORMS; RECEPTORS, ANTIGEN, T-CELL; TH2 CELLS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 13644269313     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040733     Document Type: Article

References (46)

1. Mosmann, T.R., and R.L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
2. + T cells. Annu. Rev. Immunol. 12:635-673.
3. Reiner, S.L., and R.M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151-177.
4. Abbas, A.K., K.M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature. 383:787-793.
5. Constant, S.L., and K. Bottomly. 1997. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu. Rev. Immunol. 15:297-322.
6. Nelms, K., A.D. Keegan, J. Zamorano, J.J. Ryan, and W.E. Paul. 1999. The IL-4 receptor: signaling mechanisms and biologic functions. Annu. Rev. Immunol. 17:701-738.
7. O'Garra, A. 1998. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 8:275-283.
8. Murphy, K.M., W. Ouyang, J.D. Farrar, J. Yang, S. Ranganath, H. Asnagli, M. Afkarian, and T.L. Murphy. 2000. Signaling and transcription in T helper development. Annu. Rev. Immunol. 18:451-494.
9. lck tyrosine kinase activation in Th subset differentiation. Int. Immunol. 10:577-591.
10. Yamashita, M., M. Katsumata, M. Iwashima, M. Kimura, C. Shimizu, T. Kamata, T. Shin, N. Seki, S. Suzuki, M. Taniguchi, and T. Nakayama. 2000. T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex. J. Exp. Med. 191:1869-1879.
11. Yamashita, M., M. Kimura, M. Kubo, C. Shimizu, T. Tada, R.M. Perlmutter, and T. Nakayama. 1999. T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation. Proc. Natl. Acad. Sci. USA. 96:1024-1029.
12. Kamata, T., M. Yamashita, M. Kimura, K. Murata, M. Inami, C. Shimizu, K. Sugaya, C.R. Wang, M. Taniguchi, and T. Nakayama. 2003. src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation. J. Clin. Invest. 111:109-119.
13. Zhang, D.H., L. Cohn, P. Ray, K. Bottomly, and A. Ray. 1997. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J. Biol. Chem. 272:21597-21603.
14. Zheng, W., and R.A. Flavell. 1997. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell. 89:587-596.
15. Ouyang, W., S.H. Ranganath, K. Weindel, D. Bhattacharya, T.L. Murphy, W.C. Sha, and K.M. Murphy. 1998. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity. 9:745-755.
16. Lee, H.J., N. Takemoto, H. Kurata, Y. Kamogawa, S. Miyatake, A. O'Garra, and N. Arai. 2000. GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells. J. Exp. Med. 192:105-115.
17. Szabo, S.J., S.T. Kim, G.L. Costa, X. Zhang, C.G. Fathman, and L.H. Glimcher. 2000. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 100:655-669.
18. Affolter, M., T. Marty, M.A. Vigano, and A. Jazwinska. 2001. Nuclear interpretation of Dpp signaling in Drosophila. EMBO J. 20:3298-3305.
19. Arora, K., H. Dai, S.G. Kazuko, J. Jamal, M.B. O'Connor, A. Letsou, and R. Warrior. 1995. The Drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell. 81:781-790.
20. Staehling-Hampton, K., A.S. Laughon, and F.M. Hoffmann. 1995. A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling. Development. 121:3393-3403.
21. Kingsley, D.M. 1994. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8:133-146.
22. Makino, R., K. Akiyama, J. Yasuda, S. Mashiyama, S. Honda, T. Sekiya, and K. Hayashi. 1994. Cloning and characterization of a c-myc intron binding protein (MIBP1). Nucleic Acids Res. 22:5679-5685.
23. Ron, D., A.R. Brasier, and J.F. Habener. 1991. Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc finger motif. Mol. Cell. Biol. 11:2887-2895.
24. Campbell, D.B., and P. Levitt. 2003. Regionally restricted expression of the transcription factor c-myc intron 1 binding protein during brain development. J. Comp. Neurol. 467:581-592.
25. Takagi, T., J. Harada, and S. Ishii. 2001. Murine Schnurri-2 is required for positive selection of thymocytes. Nat. Immunol. 2:1048-1053.
26. Allen, C.E., N. Muthusamy, S.E. Weisbrode, J.W. Hong, and L.C. Wu. 2002. Developmental anomalies and neoplasia in animals and cells deficient in the large zinc finger protein KRC. Genes Chromosomes Cancer. 35:287-298.
27. Barnes, P.J., and M. Karin. 1997. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066-1071.
28. Yang, L., L. Cohn, D.H. Zhang, R. Homer, A. Ray, and P. Ray. 1998. Essential role of nuclear factor κB in the induction of eosinophilia in allergic airway inflammation. J. Exp. Med. 188:1739-1750.
29. Donovan, C.E., D.A. Mark, H.Z. He, H.C. Liou, L. Kobzik, Y. Wang, G.T. De Sanctis, D.L. Perkins, and P.W. Finn. 1999. NF-κB/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation. J. Immunol. 163:6827-6833.
30. Das, J., C.H. Chen, L. Yang, L. Cohn, P. Ray, and A. Ray. 2001. A critical role for NF-κB in GATA3 expression and TH2 differentiation in allergic airway inflammation. Nat. Immunol. 2:45-50.
31. Oukka, M., S.T. Kim, G. Lugo, J. Sun, L.C. Wu, and L.H. Glimcher. 2002. A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2. Mol. Cell. 9:121-131.
32. Bachmeyer, C., C.H. Mak, C.Y. Yu, and L.C. Wu. 1999. Regulation by phosphorylation of the zinc finger protein KRC that binds the κB motif and V(D)J recombination signal sequences. Nucleic Acids Res. 27:643-648.
33. Hong, J.W., C.E. Allen, and L.C. Wu. 2003. Inhibition of NF-κB by ZAS3, a zinc-finger protein that also binds to the κB motif. Proc. Natl. Acad. Sci. USA. 100:12301-12306.
34. Bird, J.J., D.R. Brown, A.C. Mullen, N.H. Moskowitz, M.A. Mahowald, J.R. Sider, T.F. Gajewski, C.R. Wang, and S.L. Reiner. 1998. Helper T cell differentiation is controlled by the cell cycle. Immunity. 9:229-237.
35. Kubo, M., M. Yamashita, R. Abe, T. Tada, K. Okumura, J.T. Ransom, and T. Nakayama. 1999. CD28 costimulation accelerates IL-4 receptor sensitivity and IL-4-mediated Th2 differentiation. J. Immunol. 163:2432-2442.
36. Inami, M., M. Yamashita, Y. Tenda, A. Hasegawa, M. Kimura, K. Hashimoto, N. Seki, M. Taniguchi, and T. Nakayama. 2004. CD28 costimulation controls histone hyperacetylation of the interleukin 5 gene locus in developing th2 cells. J. Biol. Chem. 279:23123-23133.
37. Lieberson, R., K.A. Mowen, K.D. McBride, V. Leautaud, X. Zhang, W.K. Suh, L. Wu, and L.H. Glimcher. 2001. Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45). J. Exp. Med. 194:89-98.
38. Lee, S.Y., A. Reichlin, A. Santana, K.A. Sokol, M.C. Nussenzweig, and Y. Choi. 1997. TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival. Immunity. 7:703-713.
39. Takeda, K., T. Tanaka, W. Shi, M. Matsumoto, M. Minami, S. Kashiwamura, K. Nakanishi, N. Yoshida, T. Kishimoto, and S. Akira. 1996. Essential role of Stat6 in IL-4 signalling. Nature. 380:627-630.
40. Kimura, M., Y. Koseki, M. Yamashita, N. Watanabe, C. Shimizu, T. Katsumoto, T. Kitamura, M. Taniguchi, H. Koseki, and T. Nakayama. 2001. Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene. Immunity. 15:275-287.
41. lo thymocytes in vivo. Science. 250:1720-1723.
42. + cells by CD4. Science. 249:1558-1561.
43. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R.M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693-1702.
44. Chen-Woan, M., C.P. Delaney, V. Fournier, Y. Wakizaka, N. Murase, J. Fung, T.E. Starzl, and A.J. Demetris. 1995. A new protocol for the propagation of dendritic cells from rat bone marrow using recombinant GM-CSF, and their quantification using the mAb OX-62. J. Immunol. Methods. 178:157-171.
45. Omori, M., M. Yamashita, M. Inami, M. Ukai-Tadenuma, M. Kimura, Y. Nigo, H. Hosokawa, A. Hasegawa, M. Taniguchi, and T. Nakayama. 2003. CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA. Immunity. 19:281-294.
46. Yamashita, M., M. Ukai-Tadenuma, M. Kimura, M. Omori, M. Inami, M. Taniguchi, and T. Nakayama. 2002. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J. Biol. Chem. 277:42399-42408.