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Volumn 37, Issue 22, 2009, Pages 7691-7700

Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase α4 helix

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; MAGNESIUM ION; MANGANESE; OLIGONUCLEOTIDE; PEPTIDE DERIVATIVE;

EID: 75649146606     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp824     Document Type: Article
Times cited : (13)

References (72)
  • 2
    • 0031434606 scopus 로고    scopus 로고
    • Molecular mechanisms in retrovirus DNA integration
    • Asante-Appiah, E. and Skalka, A.M. (1997) Molecular mechanisms in retrovirus DNA integration. Antiviral Res., 36, 139-156.
    • (1997) Antiviral Res , vol.36 , pp. 139-156
    • Asante-Appiah, E.1    Skalka, A.M.2
  • 4
    • 0036163845 scopus 로고    scopus 로고
    • Slipping through the door: HIV entry into the nucleus
    • Sherman, M.P. and Greene, W.C. (2002) Slipping through the door: HIV entry into the nucleus. Microbes. Infect., 4, 67-73.
    • (2002) Microbes. Infect. , vol.4 , pp. 67-73
    • Sherman, M.P.1    Greene, W.C.2
  • 5
    • 0027179416 scopus 로고
    • Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini
    • van Gent, D.C., Oude Groeneger, A.A. and Plasterk, R.H. (1993) Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini. Nucleic Acids Res., 21, 3373-3377.
    • (1993) Nucleic Acids Res , vol.21 , pp. 3373-3377
    • van Gent, D.C.1    Oude Groeneger, A.A.2    Plasterk, R.H.3
  • 6
    • 0027179694 scopus 로고
    • Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex
    • Engelman, A., Bushman, F.D. and Craigie, R. (1993) Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex. EMBO J., 12, 3269-3275.
    • (1993) EMBO J , vol.12 , pp. 3269-3275
    • Engelman, A.1    Bushman, F.D.2    Craigie, R.3
  • 8
    • 0026649557 scopus 로고
    • Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
    • Engelman, A. and Craigie, R. (1992) Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J. Virol., 66, 6361-6369.
    • (1992) J. Virol. , vol.66 , pp. 6361-6369
    • Engelman, A.1    Craigie, R.2
  • 9
    • 0029643858 scopus 로고    scopus 로고
    • The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations
    • Bujacz, G., Jaskolski, M., Alexandratos, J., Wlodawer, A., Merkel, G., Katz, R.A. and Skalka, A.M. (1996) The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations. Structure., 4, 89-96.
    • (1996) Structure , vol.4 , pp. 89-96
    • Bujacz, G.1    Jaskolski, M.2    Alexandratos, J.3    Wlodawer, A.4    Merkel, G.5    Katz, R.A.6    Skalka, A.M.7
  • 10
    • 0028584269 scopus 로고
    • Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases
    • Dyda, F., Hickman, A.B., Jenkins, T.M., Engelman, A., Craigie, R. and Davies, D.R. (1994) Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science, 266, 1981-1986.
    • (1994) Science , vol.266 , pp. 1981-1986
    • Dyda, F.1    Hickman, A.B.2    Jenkins, T.M.3    Engelman, A.4    Craigie, R.5    Davies, D.R.6
  • 11
    • 0026719238 scopus 로고
    • Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases
    • Kulkosky, J., Jones, K.S., Katz, R.A., Mack, J.P. and Skalka, A.M. (1992) Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Mol. Cell Biol., 12, 2331-2338.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 2331-2338
    • Kulkosky, J.1    Jones, K.S.2    Katz, R.A.3    Mack, J.P.4    Skalka, A.M.5
  • 12
    • 0027470432 scopus 로고
    • Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro
    • Leavitt, A.D., Shiue, L. and Varmus, H.E. (1993) Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. J. Biol. Chem., 268, 2113-2119.
    • (1993) J. Biol. Chem. , vol.268 , pp. 2113-2119
    • Leavitt, A.D.1    Shiue, L.2    Varmus, H.E.3
  • 13
    • 0029129435 scopus 로고
    • Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration
    • Rice, P. and Mizuuchi, K. (1995) Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration. Cell, 82, 209-220.
    • (1995) Cell , vol.82 , pp. 209-220
    • Rice, P.1    Mizuuchi, K.2
  • 14
    • 0025908083 scopus 로고
    • Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase
    • Davies, J.F., Hostomska, Z., Hostomsky, Z., Jordan, S.R. and Matthews, D.A. (1991) Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase. Science, 252, 88-95.
    • (1991) Science , vol.252 , pp. 88-95
    • Davies, J.F.1    Hostomska, Z.2    Hostomsky, Z.3    Jordan, S.R.4    Matthews, D.A.5
  • 15
    • 0027377121 scopus 로고
    • Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site
    • Katayanagi, K., Okumura, M. and Morikawa, K. (1993) Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site. Proteins, 17, 337-346.
    • (1993) Proteins , vol.17 , pp. 337-346
    • Katayanagi, K.1    Okumura, M.2    Morikawa, K.3
  • 17
    • 33846272678 scopus 로고    scopus 로고
    • Single-particle image reconstruction of a tetramer of HIV integrase bound to DNA
    • Ren, G., Gao, K., Bushman, F.D. and Yeager, M. (2007) Single-particle image reconstruction of a tetramer of HIV integrase bound to DNA. J. Mol. Biol., 366, 286-294.
    • (2007) J. Mol. Biol. , vol.366 , pp. 286-294
    • Ren, G.1    Gao, K.2    Bushman, F.D.3    Yeager, M.4
  • 18
    • 0037234457 scopus 로고    scopus 로고
    • Modeling HIV-1 integrase complexes based on their hydrodynamic properties
    • Podtelezhnikov, A.A., Gao, K., Bushman, F.D. and McCammon, J.A. (2003) Modeling HIV-1 integrase complexes based on their hydrodynamic properties. Biopolymers, 68, 110-120.
    • (2003) Biopolymers , vol.68 , pp. 110-120
    • Podtelezhnikov, A.A.1    Gao, K.2    Bushman, F.D.3    McCammon, J.A.4
  • 19
    • 22144463200 scopus 로고    scopus 로고
    • Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design
    • Karki, R.G., Tang, Y., Burke, T.R. Jr and Nicklaus, M.C. (2004) Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design. J. Comput. Aided Mol. Des., 18, 739-760.
    • (2004) J. Comput. Aided Mol. Des. , vol.18 , pp. 739-760
    • Karki, R.G.1    Tang, Y.2    Burke T.R., Jr.3    Nicklaus, M.C.4
  • 20
    • 26644456674 scopus 로고    scopus 로고
    • A three-dimensional model of the human immunodeficiency virus type 1 integration complex
    • Wielens, J., Crosby, I.T. and Chalmers, D.K. (2005) A three-dimensional model of the human immunodeficiency virus type 1 integration complex. J. Comput. Aided Mol. Des., 19, 301-317.
    • (2005) J. Comput. Aided Mol. Des. , vol.19 , pp. 301-317
    • Wielens, J.1    Crosby, I.T.2    Chalmers, D.K.3
  • 21
    • 0026019625 scopus 로고
    • Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism
    • Beese, L.S. and Steitz, T.A. (1991) Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. EMBO J., 10, 25-33.
    • (1991) EMBO J , vol.10 , pp. 25-33
    • Beese, L.S.1    Steitz, T.A.2
  • 22
    • 0029083428 scopus 로고
    • Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity
    • Engelman, A. and Craigie, R. (1995) Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity. J. Virol., 69, 5908-5911.
    • (1995) J. Virol. , vol.69 , pp. 5908-5911
    • Engelman, A.1    Craigie, R.2
  • 23
    • 0032189652 scopus 로고    scopus 로고
    • Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction
    • Esposito, D. and Craigie, R. (1998) Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction. EMBO J., 17, 5832-5843.
    • (1998) EMBO J , vol.17 , pp. 5832-5843
    • Esposito, D.1    Craigie, R.2
  • 24
    • 0024431589 scopus 로고
    • The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration
    • Katzman, M., Katz, R.A., Skalka, A.M. and Leis, J. (1989) The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration. J. Virol., 63, 5319-5327.
    • (1989) J. Virol. , vol.63 , pp. 5319-5327
    • Katzman, M.1    Katz, R.A.2    Skalka, A.M.3    Leis, J.4
  • 26
    • 33645962475 scopus 로고    scopus 로고
    • Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificity
    • Yang, W., Lee, J.Y. and Nowotny, M. (2006) Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificity. Mol. Cell, 22, 5-13.
    • (2006) Mol. Cell. , vol.22 , pp. 5-13
    • Yang, W.1    Lee, J.Y.2    Nowotny, M.3
  • 27
    • 0032567350 scopus 로고    scopus 로고
    • Structural determinants of metal-induced conformational changes in HIV-1 integrase
    • Asante-Appiah, E., Seeholzer, S.H. and Skalka, A.M. (1998) Structural determinants of metal-induced conformational changes in HIV-1 integrase. J. Biol. Chem., 273, 35078-35087.
    • (1998) J. Biol. Chem. , vol.273 , pp. 35078-35087
    • Asante-Appiah, E.1    Seeholzer, S.H.2    Skalka, A.M.3
  • 30
    • 0026608073 scopus 로고
    • Environment affects amino acid preference for secondary structure
    • Zhong, L. and Johnson, W.C. Jr. (1992) Environment affects amino acid preference for secondary structure. Proc. Natl Acad. Sci. USA, 89, 4462-4465.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 4462-4465
    • Zhong, L.1    Johnson W.C., Jr.2
  • 32
    • 0024282849 scopus 로고
    • Clean Tocsy for H-1 spin system-identification in macromolecules
    • Griesinger, C., Otting, G., Wuthrich, K. and Ernst, R.R. (1988) Clean Tocsy for H-1 spin system-identification in macromolecules. J. Am. Chem. Soc., 110, 7870-7872.
    • (1988) J. Am. Chem. Soc. , vol.110 , pp. 7870-7872
    • Griesinger, C.1    Otting, G.2    Wuthrich, K.3    Ernst, R.R.4
  • 33
    • 37249085616 scopus 로고    scopus 로고
    • HIV-1 integrase inhibitors: update and perspectives
    • Semenova, E.A.M.C.a.P.Y. (2008) HIV-1 integrase inhibitors: update and perspectives. Adv. Pharmacol., 56, 199-228.
    • (2008) Adv. Pharmacol. , vol.56 , pp. 199-228
    • Semenova, E.A.M.C.a.P.Y.1
  • 34
    • 52749086245 scopus 로고    scopus 로고
    • Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors
    • Rhee, S.Y., Liu, T.F., Kiuchi, M., Zioni, R., Gifford, R.J., Holmes, S.P. and Shafer, R.W. (2008) Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors. Retrovirology, 5, 74.
    • (2008) Retrovirology , vol.5 , pp. 74
    • Rhee, S.Y.1    Liu, T.F.2    Kiuchi, M.3    Zioni, R.4    Gifford, R.J.5    Holmes, S.P.6    Shafer, R.W.7
  • 35
    • 58749105663 scopus 로고    scopus 로고
    • RNA folding: thermodynamic and molecular descriptions of the roles of ions
    • Draper, D.E. (2008) RNA folding: thermodynamic and molecular descriptions of the roles of ions. Biophys. J., 95, 5489-5495.
    • (2008) Biophys. J. , vol.95 , pp. 5489-5495
    • Draper, D.E.1
  • 36
    • 63349104786 scopus 로고    scopus 로고
    • Effects of magnesium and related divalent metal ions in topoisomerase structure and function
    • Sissi, C. and Palumbo, M. (2009) Effects of magnesium and related divalent metal ions in topoisomerase structure and function. Nucleic Acids Res., 37, 702-711.
    • (2009) Nucleic Acids Res , vol.37 , pp. 702-711
    • Sissi, C.1    Palumbo, M.2
  • 37
    • 0036312073 scopus 로고    scopus 로고
    • Structural and catalytic chemistry of magnesium-dependent enzymes
    • Cowan, J.A. (2002) Structural and catalytic chemistry of magnesium-dependent enzymes. Biometals, 15, 225-235.
    • (2002) Biometals , vol.15 , pp. 225-235
    • Cowan, J.A.1
  • 38
    • 0043037215 scopus 로고    scopus 로고
    • Cations as hydrogen bond donors: a view of electrostatic interactions in DNA
    • Subirana, J.A. and Soler-Lopez, M. (2003) Cations as hydrogen bond donors: a view of electrostatic interactions in DNA. Annu. Rev. Biophys. Biomol. Struct., 32, 27-45.
    • (2003) Annu. Rev. Biophys. Biomol. Struct. , vol.32 , pp. 27-45
    • Subirana, J.A.1    Soler-Lopez, M.2
  • 39
    • 0032419499 scopus 로고    scopus 로고
    • On the role of magnesium ions in RNA stability
    • Misra, V.K. and Draper, D.E. (1998) On the role of magnesium ions in RNA stability. Biopolymers, 48, 113-135.
    • (1998) Biopolymers , vol.48 , pp. 113-135
    • Misra, V.K.1    Draper, D.E.2
  • 40
    • 0017895903 scopus 로고
    • The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides
    • Manning, G.S. (1978) The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides. Q Rev. Biophys., 11, 179-246.
    • (1978) Q Rev. Biophys. , vol.11 , pp. 179-246
    • Manning, G.S.1
  • 41
    • 0034714010 scopus 로고    scopus 로고
    • 1 A crystal structures of B-DNA reveal sequence-specific binding and groove-specific bending of DNA by magnesium and calcium
    • Chiu, T.K. and Dickerson, R.E. (2000) 1 A crystal structures of B-DNA reveal sequence-specific binding and groove-specific bending of DNA by magnesium and calcium. J. Mol. Biol., 301, 915-945.
    • (2000) J. Mol. Biol. , vol.301 , pp. 915-945
    • Chiu, T.K.1    Dickerson, R.E.2
  • 43
    • 0033579408 scopus 로고    scopus 로고
    • The interpretation of Mg(2+) binding isotherms for nucleic acids using Poisson-Boltzmann theory
    • Misra, V.K. and Draper, D.E. (1999) The interpretation of Mg(2+) binding isotherms for nucleic acids using Poisson-Boltzmann theory. J. Mol. Biol., 294, 1135-1147.
    • (1999) J. Mol. Biol. , vol.294 , pp. 1135-1147
    • Misra, V.K.1    Draper, D.E.2
  • 44
    • 0035796559 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes
    • Gao, K., Butler, S.L. and Bushman, F. (2001) Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes. EMBO J., 20, 3565-3576.
    • (2001) EMBO J , vol.20 , pp. 3565-3576
    • Gao, K.1    Butler, S.L.2    Bushman, F.3
  • 45
    • 13444269378 scopus 로고    scopus 로고
    • Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase
    • Lu, R., Limon, A., Ghory, H.Z. and Engelman, A. (2005) Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase. J. Virol., 79, 2493-2505.
    • (2005) J. Virol. , vol.79 , pp. 2493-2505
    • Lu, R.1    Limon, A.2    Ghory, H.Z.3    Engelman, A.4
  • 48
    • 0030828521 scopus 로고    scopus 로고
    • Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking
    • Jenkins, T.M., Esposito, D., Engelman, A. and Craigie, R. (1997) Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking. EMBO J., 16, 6849-6859.
    • (1997) EMBO J , vol.16 , pp. 6849-6859
    • Jenkins, T.M.1    Esposito, D.2    Engelman, A.3    Craigie, R.4
  • 50
    • 0028034050 scopus 로고
    • Characterization of the minimal DNA-binding domain of the HIV integrase protein
    • Lutzke, R.A., Vink, C. and Plasterk, R.H. (1994) Characterization of the minimal DNA-binding domain of the HIV integrase protein. Nucleic Acids Res., 22, 4125-4131.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4125-4131
    • Lutzke, R.A.1    Vink, C.2    Plasterk, R.H.3
  • 51
    • 0032510707 scopus 로고    scopus 로고
    • Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex
    • Heuer, T.S. and Brown, P.O. (1998) Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex. Biochemistry, 37, 6667-6678.
    • (1998) Biochemistry , vol.37 , pp. 6667-6678
    • Heuer, T.S.1    Brown, P.O.2
  • 52
    • 0034824775 scopus 로고    scopus 로고
    • Mapping DNA-binding sites of HIV-1 integrase by protein footprinting
    • Dirac, A.M. and Kjems, J. (2001) Mapping DNA-binding sites of HIV-1 integrase by protein footprinting. Eur. J. Biochem., 268, 743-751.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 743-751
    • Dirac, A.M.1    Kjems, J.2
  • 53
    • 0030988998 scopus 로고    scopus 로고
    • Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase
    • Engelman, A., Liu, Y., Chen, H., Farzan, M. and Dyda, F. (1997) Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase. J. Virol., 71, 3507-3514.
    • (1997) J. Virol. , vol.71 , pp. 3507-3514
    • Engelman, A.1    Liu, Y.2    Chen, H.3    Farzan, M.4    Dyda, F.5
  • 54
    • 0031949592 scopus 로고    scopus 로고
    • Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions
    • Gerton, J.L., Ohgi, S., Olsen, M., DeRisi, J. and Brown, P.O. (1998) Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions. J. Virol., 72, 5046-5055.
    • (1998) J. Virol. , vol.72 , pp. 5046-5055
    • Gerton, J.L.1    Ohgi, S.2    Olsen, M.3    DeRisi, J.4    Brown, P.O.5
  • 55
    • 0034908087 scopus 로고    scopus 로고
    • Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection
    • Harper, A.L., Skinner, L.M., Sudol, M. and Katzman, M. (2001) Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection. J. Virol., 75, 7756-7762.
    • (2001) J. Virol. , vol.75 , pp. 7756-7762
    • Harper, A.L.1    Skinner, L.M.2    Sudol, M.3    Katzman, M.4
  • 56
    • 33645216987 scopus 로고    scopus 로고
    • Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends
    • Chen, A., Weber, I.T., Harrison, R.W. and Leis, J. (2006) Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends. J. Biol. Chem., 281, 4173-4182.
    • (2006) J. Biol. Chem. , vol.281 , pp. 4173-4182
    • Chen, A.1    Weber, I.T.2    Harrison, R.W.3    Leis, J.4
  • 57
    • 0037137609 scopus 로고    scopus 로고
    • AutoDocking dinucleotides to the HIV-1 integrase core domain: exploring possible binding sites for viral and genomic DNA
    • Perryman, A.L. and McCammon, J.A. (2002) AutoDocking dinucleotides to the HIV-1 integrase core domain: exploring possible binding sites for viral and genomic DNA. J. Med. Chem., 45, 5624-5627.
    • (2002) J. Med. Chem. , vol.45 , pp. 5624-5627
    • Perryman, A.L.1    McCammon, J.A.2
  • 58
    • 0002619244 scopus 로고
    • Effect of high salt concentrations on water structure
    • Leberman, R. and Soper, A.K. (1995) Effect of high salt concentrations on water structure. Nature, 378, 364-366.
    • (1995) Nature , vol.378 , pp. 364-366
    • Leberman, R.1    Soper, A.K.2
  • 59
    • 0034711942 scopus 로고    scopus 로고
    • Conformational flexibility of B-DNA at 0.74 A resolution: d(CCAGTACTGG)(2)
    • Kielkopf, C.L., Ding, S., Kuhn, P. and Rees, D.C. (2000) Conformational flexibility of B-DNA at 0.74 A resolution: d(CCAGTACTGG)(2). J. Mol. Biol., 296, 787-801.
    • (2000) J. Mol. Biol. , vol.296 , pp. 787-801
    • Kielkopf, C.L.1    Ding, S.2    Kuhn, P.3    Rees, D.C.4
  • 60
    • 4644229880 scopus 로고    scopus 로고
    • NMR studies of protein-nucleic acid interactions
    • Varani, G., Chen, Y. and Leeper, T.C. (2004) NMR studies of protein-nucleic acid interactions. Methods Mol. Biol., 278, 289-312.
    • (2004) Methods Mol. Biol. , vol.278 , pp. 289-312
    • Varani, G.1    Chen, Y.2    Leeper, T.C.3
  • 61
    • 38149013941 scopus 로고    scopus 로고
    • Electron spin relaxation enhancement measurements of interspin distances in human, porcine, and Rhodobacter electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO)
    • Fielding, A.J., Usselman, R.J., Watmough, N., Simkovic, M., Frerman, F.E., Eaton, G.R. and Eaton, S.S. (2008) Electron spin relaxation enhancement measurements of interspin distances in human, porcine, and Rhodobacter electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO). J. Magn Reson., 190, 222-232.
    • (2008) J. Magn Reson. , vol.190 , pp. 222-232
    • Fielding, A.J.1    Usselman, R.J.2    Watmough, N.3    Simkovic, M.4    Frerman, F.E.5    Eaton, G.R.6    Eaton, S.S.7
  • 62
    • 0028239062 scopus 로고
    • A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro
    • Ellison, V. and Brown, P.O. (1994) A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proc. Natl Acad. Sci. USA, 91, 7316-7320.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 7316-7320
    • Ellison, V.1    Brown, P.O.2
  • 63
    • 0028238134 scopus 로고
    • A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein
    • Vink, C., Banks, M., Bethell, R. and Plasterk, R.H. (1994) A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein. Nucleic Acids Res., 22, 2176-2177.
    • (1994) Nucleic Acids Res , vol.22 , pp. 2176-2177
    • Vink, C.1    Banks, M.2    Bethell, R.3    Plasterk, R.H.4
  • 66
    • 60549083469 scopus 로고    scopus 로고
    • Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes
    • Sechi, M., Carta, F., Sannia, L., Dallocchio, R., Dessi, A., Al-Safi, R.I. and Neamati, N. (2009) Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes. Antiviral Res., 81, 267-276.
    • (2009) Antiviral Res , vol.81 , pp. 267-276
    • Sechi, M.1    Carta, F.2    Sannia, L.3    Dallocchio, R.4    Dessi, A.5    Al-Safi, R.I.6    Neamati, N.7
  • 69
    • 0036529540 scopus 로고    scopus 로고
    • Structural analysis of conserved base pairs in protein-DNA complexes
    • Mirny, L.A. and Gelfand, M.S. (2002) Structural analysis of conserved base pairs in protein-DNA complexes. Nucleic Acids Res., 30, 1704-1711.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1704-1711
    • Mirny, L.A.1    Gelfand, M.S.2
  • 70
    • 0035930331 scopus 로고    scopus 로고
    • Recognition of specific DNA sequences
    • Garvie, C.W. and Wolberger, C. (2001) Recognition of specific DNA sequences. Mol. Cell, 8, 937-946.
    • (2001) Mol. Cell. , vol.8 , pp. 937-946
    • Garvie, C.W.1    Wolberger, C.2
  • 71
    • 0043236049 scopus 로고    scopus 로고
    • Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker
    • Egli, M., Tereshko, V., Mushudov, G.N., Sanishvili, R., Liu, X. and Lewis, F.D. (2003) Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker. J. Am. Chem. Soc., 125, 10842-10849.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 10842-10849
    • Egli, M.1    Tereshko, V.2    Mushudov, G.N.3    Sanishvili, R.4    Liu, X.5    Lewis, F.D.6
  • 72
    • 0037126629 scopus 로고    scopus 로고
    • Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein
    • Wang, J.Y., Ling, H., Yang, W. and Craigie, R. (2001) Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J., 20, 7333-7343.
    • (2001) EMBO J , vol.20 , pp. 7333-7343
    • Wang, J.Y.1    Ling, H.2    Yang, W.3    Craigie, R.4


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