Dynamic, thermodynamic, and kinetic basis for recognition and transformation of DNA by human immunodeficiency virus type 1 integrase

Biochemistry

Volumn 42, Issue 30, 2003, Pages 9235-9247

  Bugreev, Dmitrii V ^a   Baranova, Svetlana ^a   Zakharova, Olga D ^a   Parissi, Vincent ^b   Desjobert, Cécile ^b   Sottofattori, Enzo ^c   Balbi, Alessandro ^c   Litvak, Simon ^b   Tarrago Litvak, Laura ^b   Nevinsky, Georgy A ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DNA; ENZYMES; FREE ENERGY; IMMUNOLOGY; OLIGOMERS; SUBSTRATES; THERMODYNAMICS;

LIGAND COMPLEXITY;

BIOCHEMISTRY;

DNA; INTEGRASE; NUCLEOTIDE; OLIGONUCLEOTIDE; VIRUS DNA;

ARTICLE; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; DYNAMICS; ENERGY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; EQUILIBRIUM CONSTANT; GENOME; HUMAN IMMUNODEFICIENCY VIRUS 1; KINETICS; LIGAND BINDING; LONG TERMINAL REPEAT; MICHAELIS CONSTANT; PRIORITY JOURNAL; PROTEIN INTERACTION; RETROVIRUS; SEQUENCE ANALYSIS; THERMODYNAMICS;

DNA, SINGLE-STRANDED; DNA, VIRAL; ENZYME ACTIVATION; HIV INTEGRASE; HIV-1; HUMANS; KINETICS; MODELS, CHEMICAL; NUCLEIC ACID HETERODUPLEXES; OLIGONUCLEOTIDES; PROTEIN BINDING; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TRANSFORMATION, GENETIC;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; INSERTION SEQUENCES; UNIDENTIFIED RETROVIRUS;

EID: 0043166967     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0300480     Document Type: Article

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