Distinct antiviral signaling pathways in primary human hepatocytes and their differential disruption by HCV NS3 protease

Journal of Hepatology

Volumn 52, Issue 2, 2010, Pages 167-175

  Jouan, Loubna ^a,b   Melançon, Pierre ^a   Rodrigue Gervais, Ian Gaël ^a,b   Raymond, Valérie Ann ^a   Selliah, Subajini ^a   Boucher, Geneviève ^c   Bilodeau, Marc ^a,b   Grandvaux, Nathalie ^a,b   Lamarre, Daniel ^a,b,c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

Hepatitis C virus; Interferon stimulated genes; NS3 4A; Primary hepatocytes; Viral interference

Indexed keywords

CILUPREVIR; DOUBLE STRANDED RNA; LENTIVIRUS VECTOR; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; PATTERN RECOGNITION RECEPTOR; PROTEINASE; VIRUS PROTEIN; VIRUS RNA;

ANTIVIRAL GENE; ARTICLE; CCL5 GENE; CELL CULTURE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENETIC TRANSDUCTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IFIT1 GENE; IFNBETA GENE; IL6 GENE; IMMUNE RESPONSE; INNATE IMMUNITY; LIVER CELL; MICROARRAY ANALYSIS; MOLECULAR SENSOR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VIRUS INTERFERENCE;

CELLS, CULTURED; GENE EXPRESSION PROFILING; HEPACIVIRUS; HEPATOCYTES; HUMANS; IMMUNITY, INNATE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 75549086227     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2009.11.011     Document Type: Article

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