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33746903357
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Definitive endoderm of the mouse embryo: Formation, cell fates and morphogenetic function
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This is a comprehensive review of endoderm formation, differentiation and morphogenesis
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Lewis SL, Tam PL. Definitive endoderm of the mouse embryo: formation, cell fates and morphogenetic function. Dev Dynamics 2006; 235:2315-2329. This is a comprehensive review of endoderm formation, differentiation and morphogenesis.
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(2006)
Dev Dynamics
, vol.235
, pp. 2315-2329
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Lewis, S.L.1
Tam, P.L.2
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2
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25144456045
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Functional specification in the Drosophila endoderm
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This is an extensive review of Drosophila endoderm formation
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Nakagoshi H. Functional specification in the Drosophila endoderm. Develop Growth Differ 2005; 47:383-392. This is an extensive review of Drosophila endoderm formation.
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(2005)
Develop Growth Differ
, vol.47
, pp. 383-392
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Nakagoshi, H.1
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3
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0036158611
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In vitro functional gut-like organ formation from embryonic stem cells
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Yamada T, Yoshikawa M, Takaki M, et al. In vitro functional gut-like organ formation from embryonic stem cells. Stem Cells 2002; 20:41-49.
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(2002)
Stem Cells
, vol.20
, pp. 41-49
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Yamada, T.1
Yoshikawa, M.2
Takaki, M.3
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4
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18344406019
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Characterization of in vitro gutlike organ formed from mouse embryonic stem cells
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Ishikawa T, Nakayama S, Nakagawa T, et al. Characterization of in vitro gutlike organ formed from mouse embryonic stem cells. Am J Physiol (Cell Physiol) 2004; 286:C1344-C1352.
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(2004)
Am J Physiol (Cell Physiol)
, vol.286
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Ishikawa, T.1
Nakayama, S.2
Nakagawa, T.3
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5
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33745004426
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Crucial transcription factors in endoderm and embryonic gut development are expressed in gut-like structures from mouse ES cells
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Embryoid bodies recapitulate many features of normal gut ontogeny and may provide a novel model system for studying morphogenesis
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Matsuura R, Kogo H, Ogaeri T, Miwa T, et al. Crucial transcription factors in endoderm and embryonic gut development are expressed in gut-like structures from mouse ES cells. Stem Cells 2006; 24:624-630. Embryoid bodies recapitulate many features of normal gut ontogeny and may provide a novel model system for studying morphogenesis.
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(2006)
Stem Cells
, vol.24
, pp. 624-630
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Matsuura, R.1
Kogo, H.2
Ogaeri, T.3
Miwa, T.4
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6
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29744461931
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Dessimoz J, Opoka R, Kordich JJ, et al. FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo. Mech Dev 2006; 123:42-55. FGF4 plays a critical role in anterior-posterior axis patterning.
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Dessimoz J, Opoka R, Kordich JJ, et al. FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo. Mech Dev 2006; 123:42-55. FGF4 plays a critical role in anterior-posterior axis patterning.
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7
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30344433300
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The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia
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Fairbanks TJ, Sala FG, Kanard R, et al. The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia. J Pediatr Surg 2006; 41:132-136.
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(2006)
J Pediatr Surg
, vol.41
, pp. 132-136
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Fairbanks, T.J.1
Sala, F.G.2
Kanard, R.3
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8
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25844505439
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Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis
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This paper provides critical information for zebrafish gut researchers, reporting a detailed analysis of zebrafish epithelial morphogenesis and generation of a novel transgenic model for evaluating enteroendocrine cells
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Ng ANY, de Jong-Curtain TA, Mawdsley DJ, et al. Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. Dev Biol 2005; 286:114-135. This paper provides critical information for zebrafish gut researchers, reporting a detailed analysis of zebrafish epithelial morphogenesis and generation of a novel transgenic model for evaluating enteroendocrine cells.
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(2005)
Dev Biol
, vol.286
, pp. 114-135
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ANY, N.1
de Jong-Curtain, T.A.2
Mawdsley, D.J.3
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9
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33746966624
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Lipscomb K, Schmitt C, Sablyak A, et al. Role for retinoid signaling in leftright asymmetric digestive organ morphogenesis. Dev Dyn 2006; 235:2266-2275. The authors provide a detailed analysis of the role of retinoid signaling in gut looping/rotation.
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Lipscomb K, Schmitt C, Sablyak A, et al. Role for retinoid signaling in leftright asymmetric digestive organ morphogenesis. Dev Dyn 2006; 235:2266-2275. The authors provide a detailed analysis of the role of retinoid signaling in gut looping/rotation.
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10
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33845191713
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Bosse T, Piaseckyj CM, Burghard E, et al. Gata 4 is essential for maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol Cell Biol 2006; Aug 28 [Epub ahead of print]. The authors describe an elegant study of the effects of gut-specific Gata4 knockout, resulting in 'ilealization' of the jejunum.
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Bosse T, Piaseckyj CM, Burghard E, et al. Gata 4 is essential for maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol Cell Biol 2006; Aug 28 [Epub ahead of print]. The authors describe an elegant study of the effects of gut-specific Gata4 knockout, resulting in 'ilealization' of the jejunum.
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11
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33344469569
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Spatio-temporal patterns of intestine-specific transcription factor expression during postnatal mouse gut development
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This is a detailed analysis of expression patterns of transcription factors that have important roles in gut ontogeny
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Fang R, Olds LC, Sibley E. Spatio-temporal patterns of intestine-specific transcription factor expression during postnatal mouse gut development. Gene Expression Patterns 2006; 6:426-432. This is a detailed analysis of expression patterns of transcription factors that have important roles in gut ontogeny.
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(2006)
Gene Expression Patterns
, vol.6
, pp. 426-432
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Fang, R.1
Olds, L.C.2
Sibley, E.3
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12
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0034928794
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Gene targeting reveals a crucial role for MTG8 in the gut
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Calabi F, Pannell R, Pavloska G. Gene targeting reveals a crucial role for MTG8 in the gut. Mol Cell Biol 2001; 21:5658-5660.
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(2001)
Mol Cell Biol
, vol.21
, pp. 5658-5660
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Calabi, F.1
Pannell, R.2
Pavloska, G.3
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13
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27144543553
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Amann JM, Irvin Chyla BJ, Ellis TC, et al. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Mol Cell Biol 2005; 25:9576-9585. This interesting study suggested a novel role for Mtgr1 in secretory cell lineage maintenance.
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Amann JM, Irvin Chyla BJ, Ellis TC, et al. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Mol Cell Biol 2005; 25:9576-9585. This interesting study suggested a novel role for Mtgr1 in secretory cell lineage maintenance.
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14
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33746682493
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Varnat F, Bordier-Ten Heggeler B, Grisel P, et al. PPARβ/δ regulates Paneth cell differentiation via controlling the Hedgehog signaling pathway. Gastroenterology 2006; 131:538-553. Novel observations of the role of PPARβ/δ and intersection with the Hh signaling pathway in Paneth cell differentiation.
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Varnat F, Bordier-Ten Heggeler B, Grisel P, et al. PPARβ/δ regulates Paneth cell differentiation via controlling the Hedgehog signaling pathway. Gastroenterology 2006; 131:538-553. Novel observations of the role of PPARβ/δ and intersection with the Hh signaling pathway in Paneth cell differentiation.
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15
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33745437746
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Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine
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This elegant study indicated a unique role for this important tyrosine kinase
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Haegebarth A, Bie W, Yang R, et al. Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. Mol Cell Biol 2006; 26:4949-4957. This elegant study indicated a unique role for this important tyrosine kinase.
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(2006)
Mol Cell Biol
, vol.26
, pp. 4949-4957
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Haegebarth, A.1
Bie, W.2
Yang, R.3
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16
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0035824487
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Requirement of Math 2 for secretory cell lineage in the mouse intestine
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Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY. Requirement of Math 2 for secretory cell lineage in the mouse intestine. Science 2001; 294:2155-2158.
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(2001)
Science
, vol.294
, pp. 2155-2158
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Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
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17
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26944474424
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Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation
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This elegant study sheds further light on molecular regulation of gut epithelial differentiation
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Shroyer NF, Wallis D, Venken KJT, et al. Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev 2005; 19:2412-2417. This elegant study sheds further light on molecular regulation of gut epithelial differentiation.
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(2005)
Genes Dev
, vol.19
, pp. 2412-2417
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Shroyer, N.F.1
Wallis, D.2
Venken, K.J.T.3
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18
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25444491191
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Overlapping gene expression in fetal mouse intestine development and human colorectal cancer
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This presents a novel statistical approach to analyze and compare expression profiles in cancer and development
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Hu M, Shivdasani RA. Overlapping gene expression in fetal mouse intestine development and human colorectal cancer. Cancer Res 2005; 65:8715-8722. This presents a novel statistical approach to analyze and compare expression profiles in cancer and development.
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(2005)
Cancer Res
, vol.65
, pp. 8715-8722
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Hu, M.1
Shivdasani, R.A.2
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19
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0032524069
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Mutations in the SMAD4/DPC4 gene in juvenile polyposis
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Howe JR, Roth S, Ringold JC, et al. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 1998; 280:1086-1088.
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(1998)
Science
, vol.280
, pp. 1086-1088
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Howe, J.R.1
Roth, S.2
Ringold, J.C.3
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20
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0034972978
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Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
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Howe JR, Bair JL, Sayed MG, et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet 2001; 28:184-187.
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(2001)
Nat Genet
, vol.28
, pp. 184-187
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Howe, J.R.1
Bair, J.L.2
Sayed, M.G.3
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21
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33646894742
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Batts LE, Polk DB, Dubois RN, Kulessa H. Bmp signaling is required for intestinal growth and morphogenesis. Dev Dyn 2006; 235:1563-1570. This study provided important confirmatory data that Bmp signaling is critical for regulating proliferation and crypt formation in the gut and expands observations to include the colon and implicate Hh and Pdgf signaling in juvenile polyposis.
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Batts LE, Polk DB, Dubois RN, Kulessa H. Bmp signaling is required for intestinal growth and morphogenesis. Dev Dyn 2006; 235:1563-1570. This study provided important confirmatory data that Bmp signaling is critical for regulating proliferation and crypt formation in the gut and expands observations to include the colon and implicate Hh and Pdgf signaling in juvenile polyposis.
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22
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1542618115
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De novo crypt formation and juvenile polyposis on Bmp inhibition in mouse intestine
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Haramis AG, Begthel H, van den Born M, et al. De novo crypt formation and juvenile polyposis on Bmp inhibition in mouse intestine. Science 2004; 303:1684-1686.
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(2004)
Science
, vol.303
, pp. 1684-1686
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Haramis, A.G.1
Begthel, H.2
van den Born, M.3
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23
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0036897340
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Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis
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Fritsch C, Swietlicki EA, Lefebvre O, et al. Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis. J Clin Invest 2002; 110: 1629-1641.
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(2002)
J Clin Invest
, vol.110
, pp. 1629-1641
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Fritsch, C.1
Swietlicki, E.A.2
Lefebvre, O.3
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24
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33745205659
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-/- mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis
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Deletion of a myofibroblast protein resulted in altered epithelial proliferation and crypt fission in the developing postnatal gut, affecting Bmp and β-catenin signaling pathways
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-/- mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis. J Clin Invest 2006; 116:1535-1546. Deletion of a myofibroblast protein resulted in altered epithelial proliferation and crypt fission in the developing postnatal gut, affecting Bmp and β-catenin signaling pathways.
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(2006)
J Clin Invest
, vol.116
, pp. 1535-1546
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Wang, Y.1
Wang, L.2
Iordanov, H.3
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25
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0030907001
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The mesenchymal winged helix transcription factor Fkh6 is required for the control of small intestinal proliferation and differentiation
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Kaestner KH, Silberg DG, Traber PG, Schutz G. The mesenchymal winged helix transcription factor Fkh6 is required for the control of small intestinal proliferation and differentiation. Genes Dev 1997; 11:1583-1595.
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(1997)
Genes Dev
, vol.11
, pp. 1583-1595
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Kaestner, K.H.1
Silberg, D.G.2
Traber, P.G.3
Schutz, G.4
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26
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33745798204
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Takano-Maruyama M, Hase K, Fukamachi H, et al. Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine. Am J Physiol Gastrointest Liver Physiol 2006; 291:G163-G170. Further analysis of the Foxl1 deficient mouse indicates aberrant Paneth cell localization and ectopic expression of ephrins.
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Takano-Maruyama M, Hase K, Fukamachi H, et al. Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine. Am J Physiol Gastrointest Liver Physiol 2006; 291:G163-G170. Further analysis of the Foxl1 deficient mouse indicates aberrant Paneth cell localization and ectopic expression of ephrins.
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27
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0035146670
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The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm
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Malapuu M, Ormestad M, Enerback S, Carlsson P. The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm. Development 2001; 128:155-166.
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(2001)
Development
, vol.128
, pp. 155-166
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Malapuu, M.1
Ormestad, M.2
Enerback, S.3
Carlsson, P.4
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28
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4444309406
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Function and regulation of Foxf1 during Xenopus gut development
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Tseng HT, Shah R, Jamrich M. Function and regulation of Foxf1 during Xenopus gut development. Development 2004; 131:3637-3647.
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(2004)
Development
, vol.131
, pp. 3637-3647
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Tseng, H.T.1
Shah, R.2
Jamrich, M.3
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29
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0038044736
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Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal devleopment of secondary palate
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Wang T, Tamakoshi T, Uezato T, et al. Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal devleopment of secondary palate. Dev Biol 2003; 259:83-94.
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(2003)
Dev Biol
, vol.259
, pp. 83-94
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Wang, T.1
Tamakoshi, T.2
Uezato, T.3
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33645535002
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Ormestad M, Astorga J, Landgren H, et al. Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production. Development 2005; 133:833-843. Elegant studies of Foxf2 null mice and mice in which one allele of Foxf1 and Foxf2 each are inactivated reveal novel roles for these transcription factors in gut ontogeny, including maintenance of the extracellular matrix, regulation of proliferation and apoptosis.
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Ormestad M, Astorga J, Landgren H, et al. Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production. Development 2005; 133:833-843. Elegant studies of Foxf2 null mice and mice in which one allele of Foxf1 and Foxf2 each are inactivated reveal novel roles for these transcription factors in gut ontogeny, including maintenance of the extracellular matrix, regulation of proliferation and apoptosis.
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