Structural and functional studies of Aspergillus clavatus N 5-carboxyaminoimidazole ribonucleotide synthetase

Biochemistry

Volumn 49, Issue 4, 2010, Pages 752-760

  Thoden, James B ^a   Holden, Hazel M ^a   Paritala, Hanumantharao ^b   Firestine, Steven M ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AMINO ACID RESIDUES; AMINO GROUP; ANTIMICROBIAL DRUG; CATALYTIC MECHANISMS; GENERAL BASE; INORGANIC PHOSPHATES; KEY ENZYMES; KINETIC DATA; RIBONUCLEOTIDES; SITE DIRECTED MUTAGENESIS; SUBSTRATE BINDING; SYNTHETASES;

AMINO ACIDS; BIOCHEMISTRY; CATALYSIS; CLONING; ENZYME ACTIVITY; ORGANIC ACIDS; QUANTUM CHEMISTRY; STRUCTURAL ANALYSIS; THREE DIMENSIONAL;

ENZYMES;

ADENOSINE DIPHOSPHATE MAGNESIUM; ADENOSINE TRIPHOSPHATE MAGNESIUM; ASPARTIC ACID; BICARBONATE; CARBON DIOXIDE; FUNGAL ENZYME; LYSINE; N5 CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE; PHOSPHATE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS; ASPERGILLUS CLAVATUS; CATALYSIS; CONTROLLED STUDY; CRYSTALLIZATION; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENE MUTATION; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PURINE METABOLISM; STRUCTURE ANALYSIS;

ADENOSINE DIPHOSPHATE; AMINOIMIDAZOLE CARBOXAMIDE; ASPERGILLUS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; KINETICS; LIGASES; RIBONUCLEOTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ASPERGILLUS CLAVATUS;

EID: 75149192731     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901599u     Document Type: Article

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