Activated factor X cleaves factor VIII at arginine 562, limiting its cofactor efficiency

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 2, 2010, Pages 286-293

  Plantier, J L ^a   Rolli, V ^b   Ducasse, C ^c   Dargaud, Y ^a   Enjolras, N ^a   Boukerche, H ^a   Negrier C ^a  

^a UNIVERSITÉ LYON 1   (France)

^b Inst de Rech en Hématologie   (France)

^c MINATEC   (France)

Author keywords

Coagulation; Factor VIII; Factor Xa; Hemostasis; Proteolysis

Indexed keywords

ARGININE; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; PHOSPHOLIPID; VON WILLEBRAND FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; GENE MUTATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN;

EID: 74749089803     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03675.x     Document Type: Article

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