-
1
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science. 1986;232:34-47.
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
2
-
-
0000063546
-
Lipoprotein receptors: New roles for ancient proteins
-
Willnow TE, Nykjaer A, Herz J. Lipoprotein receptors: new roles for ancient proteins. Nat Cell Biol. 1999;1:157-162.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 157-162
-
-
Willnow, T.E.1
Nykjaer, A.2
Herz, J.3
-
3
-
-
0000600880
-
Familial hypercholesterolemia
-
Scriver CR, Beaudet AL, Sly WS, VaIIe D, eds. New York, NY: McGraw-Hill
-
Goldstein JL, Hobbs HH, Brown MS. Familial hypercholesterolemia. In: Scriver CR, Beaudet AL, Sly WS, VaIIe D, eds. The Metabolic and Molecular Bases of Inherited Disease. Vol 2. New York, NY: McGraw-Hill; 2001:2863-2913.
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
, vol.2
, pp. 2863-2913
-
-
Goldstein, J.L.1
Hobbs, H.H.2
Brown, M.S.3
-
4
-
-
0141832797
-
Diverse role of LDL receptor-related protein in the clearance of proteases and in signalling
-
Strickland DK, Ranganathan S. Diverse role of LDL receptor-related protein in the clearance of proteases and in signalling. J Thromb Haemost. 2003;1:1663-1670.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 1663-1670
-
-
Strickland, D.K.1
Ranganathan, S.2
-
5
-
-
0034812412
-
The roles of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family
-
Bu G. The roles of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family. Int Rev Cytol. 2001;209: 76-116.
-
(2001)
Int Rev Cytol
, vol.209
, pp. 76-116
-
-
Bu, G.1
-
6
-
-
0032004972
-
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
-
Rohlmann A, Gotthardt M, Hammer RE, Herz J. Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. J Clin Invest. 1998;101:689-695.
-
(1998)
J Clin Invest
, vol.101
, pp. 689-695
-
-
Rohlmann, A.1
Gotthardt, M.2
Hammer, R.E.3
Herz, J.4
-
7
-
-
0033588163
-
The light chain of factor VIII comprises a binding site for low density lipoprotein receptor-related protein
-
Lenting PJ, Neels JG, van den Berg BMM, et al. The light chain of factor VIII comprises a binding site for low density lipoprotein receptor-related protein. J Biol Chem. 1999;274:23734-23739.
-
(1999)
J Biol Chem
, vol.274
, pp. 23734-23739
-
-
Lenting, P.J.1
Neels, J.G.2
Van Den Berg, B.M.M.3
-
8
-
-
0033621486
-
Role of the low density lipoprolein-related protein receptor in mediation of factor VIII catabolism
-
Saenko EL, Yakhyaev AV, Mikhailenko I, Strickland DK, Sarafanov AG. Role of the low density lipoprolein-related protein receptor in mediation of factor VIII catabolism. J Biol Chem. 1999;274: 37685-37692.
-
(1999)
J Biol Chem
, vol.274
, pp. 37685-37692
-
-
Saenko, E.L.1
Yakhyaev, A.V.2
Mikhailenko, I.3
Strickland, D.K.4
Sarafanov, A.G.5
-
9
-
-
0032402122
-
The life cycle of coagulation factor VIII in view of its structure and function
-
Lenting PJ, van Mourik JA, Mertens K. The life cycle of coagulation factor VIII in view of its structure and function. Blood. 1998;92:3983-3996.
-
(1998)
Blood
, vol.92
, pp. 3983-3996
-
-
Lenting, P.J.1
Van Mourik, J.A.2
Mertens, K.3
-
10
-
-
0028814316
-
Role of clotting factor VIII in efrect of von Willebrand factor on occurrence of deep-vein thrombosis
-
Koster T, Blann AD, Briet E, Vanderbroucke JP, Rosendaal FR. Role of clotting factor VIII in efrect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet 1995;344:152-155.
-
(1995)
Lancet
, vol.344
, pp. 152-155
-
-
Koster, T.1
Blann, A.D.2
Briet, E.3
Vanderbroucke, J.P.4
Rosendaal, F.R.5
-
12
-
-
0031686041
-
Biochemistry and genetics of von Willebrand factor
-
Sadler JE. Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem. 1998;67:395-424.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 395-424
-
-
Sadler, J.E.1
-
13
-
-
0037926885
-
Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency
-
Bovenschen N, Herz J, Grimbergen JM, et al. Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency. Blood. 2003;101:3933-3939.
-
(2003)
Blood
, vol.101
, pp. 3933-3939
-
-
Bovenschen, N.1
Herz, J.2
Grimbergen, J.M.3
-
14
-
-
4544305933
-
Very low density lipoprotein receptor interacts with coagulation factor VIII
-
Abstract 301
-
Kouiavskaia DV, Ruiz JF, Strickland DK, Saenko EL. Very low density lipoprotein receptor interacts with coagulation factor VIII [abstract]. Blood. 2003;102:88. Abstract 301.
-
(2003)
Blood
, vol.102
, pp. 88
-
-
Kouiavskaia, D.V.1
Ruiz, J.F.2
Strickland, D.K.3
Saenko, E.L.4
-
15
-
-
4544310501
-
Clearance of coagulation factor VIII in very low-density lipoprotein knockout mice
-
Bovenschen N, Willems van Dijk K, Havekes LM, Mertens K, van Vlijmen BJM. Clearance of coagulation factor VIII in very low-density lipoprotein knockout mice. Br J Haematol. 2004;126:722-725.
-
(2004)
Br J Haematol
, vol.126
, pp. 722-725
-
-
Bovenschen, N.1
Willems Van Dijk, K.2
Havekes, L.M.3
Mertens, K.4
Van Vlijmen, B.J.M.5
-
16
-
-
0024468983
-
Inhibition of human coagulation factor VIII by monoclonal antibodies: Mapping of functional epitopes with the use of recombinant factor VIII fragments
-
Leyte A, Mertens K, Distel B, et al. Inhibition of human coagulation factor VIII by monoclonal antibodies: mapping of functional epitopes with the use of recombinant factor VIII fragments. Biochem J. 1989;263:187-194.
-
(1989)
Biochem J.
, vol.263
, pp. 187-194
-
-
Leyte, A.1
Mertens, K.2
Distel, B.3
-
17
-
-
0021249145
-
Characterization of 25 monoclonal antibodies to factor VIII-von Willebrand factor: Relationship between ristocetin-induced platelet aggregation and platelet adherence to subendothelium
-
Stel HV, Sakariassen KS, Scholte BJ, et al. Characterization of 25 monoclonal antibodies to factor VIII-von Willebrand factor: relationship between ristocetin-induced platelet aggregation and platelet adherence to subendothelium. Blood. 1984; 63:1408-1415.
-
(1984)
Blood
, vol.63
, pp. 1408-1415
-
-
Stel, H.V.1
Sakariassen, K.S.2
Scholte, B.J.3
-
18
-
-
0037646472
-
Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein
-
Rohlena J, Kolkman JA, Boertjes RC, Mertens K, Lenting PJ. Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein. J Biol Chem. 2003;278:9394-9401.
-
(2003)
J Biol Chem
, vol.278
, pp. 9394-9401
-
-
Rohlena, J.1
Kolkman, J.A.2
Boertjes, R.C.3
Mertens, K.4
Lenting, P.J.5
-
19
-
-
0028239173
-
Identification of a binding site for blood coagulation factor IXa on the light chain of human factor VIII
-
Lenting PJ, Donath MJSH, van Mourik JA, Mertens K. Identification of a binding site for blood coagulation factor IXa on the light chain of human factor VIII. J Biol Chem. 1994;269:7150-7155.
-
(1994)
J Biol Chem
, vol.269
, pp. 7150-7155
-
-
Lenting, P.J.1
Donath, M.J.S.H.2
Van Mourik, J.A.3
Mertens, K.4
-
20
-
-
0025786502
-
39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor
-
Herz J, Goldstein JL, Strickland DK, Ho YK, Brown MS. 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. J Biol Chem. 1991;266:21232-21238.
-
(1991)
J Biol Chem
, vol.266
, pp. 21232-21238
-
-
Herz, J.1
Goldstein, J.L.2
Strickland, D.K.3
Ho, Y.K.4
Brown, M.S.5
-
21
-
-
0027174832
-
Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia
-
van den Maagdenberg AMJM, Hofker MH, Krimpenfort PJA, et al. Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia. J Biol Chem. 1993;268:10540-10545.
-
(1993)
J Biol Chem
, vol.268
, pp. 10540-10545
-
-
Van Den Maagdenberg, A.M.J.M.1
Hofker, M.H.2
Krimpenfort, P.J.A.3
-
22
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
23
-
-
0027258140
-
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest. 1993;92:883-893.
-
(1993)
J Clin Invest
, vol.92
, pp. 883-893
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
24
-
-
0027409026
-
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice
-
Herz J, Gerard RD. Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc Natl Acad Sci USA. 1993;90:2812-2816.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2812-2816
-
-
Herz, J.1
Gerard, R.D.2
-
25
-
-
0033615548
-
The second and fourth cluster of class a cysteine-rich iepeats of the low density lipoprotein receptor-related protein share ligand-binding properties
-
Neels JG, van den Berg BMM, Lookene A, Olivecrona G, Pannekoek H, van Zonneveld AJ. The second and fourth cluster of class A cysteine-rich iepeats of the low density lipoprotein receptor-related protein share ligand-binding properties. J Biol Chem. 1999;274:31305-31311.
-
(1999)
J Biol Chem
, vol.274
, pp. 31305-31311
-
-
Neels, J.G.1
Van Den Berg, B.M.M.2
Lookene, A.3
Olivecrona, G.4
Pannekoek, H.5
Van Zonneveld, A.J.6
-
26
-
-
0026756089
-
Low density lipoprotein receptor-related protein/ alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator
-
Bu G, Williams S, Strickland DK, Schwartz AL. Low density lipoprotein receptor-related protein/ alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator. Proc Natl Acad Sci U S A. 1992;89:7427-7431.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 7427-7431
-
-
Bu, G.1
Williams, S.2
Strickland, D.K.3
Schwartz, A.L.4
-
27
-
-
0029959746
-
Sustained somatic gene inactivation by viral transfer of Cre recombinase
-
Rohlmann A, Gotthardt M, Willnow TE, Hammer RE, Herz J. Sustained somatic gene inactivation by viral transfer of Cre recombinase. Nat Biotechnol. 1996;14:1562-1565.
-
(1996)
Nat Biotechnol
, vol.14
, pp. 1562-1565
-
-
Rohlmann, A.1
Gotthardt, M.2
Willnow, T.E.3
Hammer, R.E.4
Herz, J.5
-
28
-
-
0028215636
-
Diet-induced hyperlipoproteinemia and atherosclerosis in apoliprotein E3-Leiden transgenic mice
-
van Vlijmen BJM, van den Maagdenberg AMJM, Gijbels MJJ, et al. Diet-induced hyperlipoproteinemia and atherosclerosis in apoliprotein E3-Leiden transgenic mice. J Clin Invest. 1994;93:1403-1410.
-
(1994)
J Clin Invest
, vol.93
, pp. 1403-1410
-
-
Van Vlijmen, B.J.M.1
Van Den Maagdenberg, A.M.J.M.2
Gijbels, M.J.J.3
-
29
-
-
0029115499
-
Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor
-
Frykman PK, Brown MS, Yamamoto T, Goldstein JL, Herz J. Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. Proc Natl Acad Sci USA. 1995;92:8453-8457.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8453-8457
-
-
Frykman, P.K.1
Brown, M.S.2
Yamamoto, T.3
Goldstein, J.L.4
Herz, J.5
-
30
-
-
0029851509
-
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway
-
Jong MC, Dahlmans VEH, van Gorp PJJ, et al. In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway. J Clin Invest. 1996;98:2259-2267.
-
(1996)
J Clin Invest
, vol.98
, pp. 2259-2267
-
-
Jong, M.C.1
Dahlmans, V.E.H.2
Van Gorp, P.J.J.3
-
31
-
-
0031028921
-
The pharmacokinetics of factor VIII and factor IX: Methodology, pitfalls and applications
-
Björkman S, Carlsson M. The pharmacokinetics of factor VIII and factor IX: methodology, pitfalls and applications. Haemophilia. 1997;3:1-8.
-
(1997)
Haemophilia
, vol.3
, pp. 1-8
-
-
Björkman, S.1
Carlsson, M.2
-
32
-
-
0028284556
-
Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
-
Willnow TE, Sheng Z, Ishibashi S, Herz J. Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist. Science. 1994;264:1471-1474.
-
(1994)
Science
, vol.264
, pp. 1471-1474
-
-
Willnow, T.E.1
Sheng, Z.2
Ishibashi, S.3
Herz, J.4
-
33
-
-
0037646492
-
Low-density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII
-
Bovenschen N, Boertjes RC, van Stempvoort G, et al. Low-density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII. J Biol Chem. 2003;278:9370-9377.
-
(2003)
J Biol Chem
, vol.278
, pp. 9370-9377
-
-
Bovenschen, N.1
Boertjes, R.C.2
Van Stempvoort, G.3
-
34
-
-
0032509268
-
Soluble LDL minireceptors: Minimal structure requirements for recognition of minor group human rhinovirus
-
Marlovits TC, Abrahamsberg C, Blaas D. Soluble LDL minireceptors: minimal structure requirements for recognition of minor group human rhinovirus. J Biol Chem. 1998;273:33835-33840.
-
(1998)
J Biol Chem
, vol.273
, pp. 33835-33840
-
-
Marlovits, T.C.1
Abrahamsberg, C.2
Blaas, D.3
-
35
-
-
0028912587
-
The 39-kDa receptor-associated protein modulates lipoprotein catabolism by binding to LDL receptors
-
Medh JD, Fry GL, Bowen SL, Pladet MW, Strickland DK, Chappell DA. The 39-kDa receptor-associated protein modulates lipoprotein catabolism by binding to LDL receptors. J Biol Chem. 1995; 270:536-540.
-
(1995)
J Biol Chem
, vol.270
, pp. 536-540
-
-
Medh, J.D.1
Fry, G.L.2
Bowen, S.L.3
Pladet, M.W.4
Strickland, D.K.5
Chappell, D.A.6
-
36
-
-
0028268018
-
The two-receptor model of lipoprotein clearance: Tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins
-
Ishibashi S, Herz J, Maeda N, Goldstein JL, Brawn MS. The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc Natl Acad Sci U S A. 1994;91:4431-4435.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4431-4435
-
-
Ishibashi, S.1
Herz, J.2
Maeda, N.3
Goldstein, J.L.4
Brawn, M.S.5
-
37
-
-
2342615453
-
Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol
-
Espirito Santo SMS, Pires NMM, Boesten LSM, et al. Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol. Blood. 2004;103:3777-3782.
-
(2004)
Blood
, vol.103
, pp. 3777-3782
-
-
Espirito Santo, S.M.S.1
Pires, N.M.M.2
Boesten, L.S.M.3
-
38
-
-
3442880397
-
The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis
-
Goudriaan JR, Espirito Santo SMS, Voshol PJ, et al. The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis. J Lipid Res. 2004;45: 1475-1481.
-
(2004)
J Lipid Res
, vol.45
, pp. 1475-1481
-
-
Goudriaan, J.R.1
Espirito Santo, S.M.S.2
Voshol, P.J.3
-
39
-
-
0035853843
-
Cell surface heparan sulfate proteoglycans participate in factor VIII catabolism mediated by low density lipoprotein receptor-related protein
-
Sarafanov AG, Ananyeva NM, Shima M, Saenko EL. Cell surface heparan sulfate proteoglycans participate in factor VIII catabolism mediated by low density lipoprotein receptor-related protein. J Biol Chem. 2001;276:11970-11979.
-
(2001)
J Biol Chem
, vol.276
, pp. 11970-11979
-
-
Sarafanov, A.G.1
Ananyeva, N.M.2
Shima, M.3
Saenko, E.L.4
-
40
-
-
0027990682
-
Secretion-capture role for apolipoprotein e in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans
-
Ji ZS, Fazio S, Lee YL, Mahley RW. Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans. J Biol Chem. 1994; 269:2764-2772.
-
(1994)
J Biol Chem
, vol.269
, pp. 2764-2772
-
-
Ji, Z.S.1
Fazio, S.2
Lee, Y.L.3
Mahley, R.W.4
-
41
-
-
0024391837
-
Stoichiometric binding of low density lipoprotein (LDL) and monoclonal antibodies to LDL receptors in a solid phase assay
-
van Driel IR, Brown MS, Goldstein JL. Stoichiometric binding of low density lipoprotein (LDL) and monoclonal antibodies to LDL receptors in a solid phase assay. J Biol Chem. 1989;264:9533-9538.
-
(1989)
J Biol Chem
, vol.264
, pp. 9533-9538
-
-
Van Driel, I.R.1
Brown, M.S.2
Goldstein, J.L.3
-
42
-
-
0035947646
-
Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates
-
Li Y, Lu W, Paz Marzolo M, Bu G. Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates. J Biol Chem. 2001;276:18000-18006.
-
(2001)
J Biol Chem
, vol.276
, pp. 18000-18006
-
-
Li, Y.1
Lu, W.2
Paz Marzolo, M.3
Bu, G.4
-
43
-
-
0033862227
-
The factor VIII acute phase response requires the participation of NFκB and C/EBP
-
Begbie M, Notley C, Tinlin S, Sawyer L, Lillicrap D. The factor VIII acute phase response requires the participation of NFκB and C/EBP. Thromb Haemost. 2000;84:216-222.
-
(2000)
Thromb Haemost
, vol.84
, pp. 216-222
-
-
Begbie, M.1
Notley, C.2
Tinlin, S.3
Sawyer, L.4
Lillicrap, D.5
-
44
-
-
0035863915
-
Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models
-
Denis CV, Kwack K, Saffaripour S, et al. Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models. Blood. 2001; 97:465-472.
-
(2001)
Blood
, vol.97
, pp. 465-472
-
-
Denis, C.V.1
Kwack, K.2
Saffaripour, S.3
|