Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain

Journal of Biological Chemistry

Volumn 279, Issue 32, 2004, Pages 33104-33113

  Nogami, Keiji ^a   Freas, Jan ^a   Manithody, Chandrashekhara ^b   Wakabayashi, Hironao ^a   Rezaie, Alireza R ^b   Fay, Philip J ^a,c  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; ENZYMES;

CLEAVAGE; MUTANTS; PHASE BINDING;

BIOCHEMISTRY;

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 8; HEPARIN; RECOMBINANT BLOOD CLOTTING FACTOR 8; SEPHAROSE;

ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CROSS LINKING; HEMOPHILIA A; MUTANT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; WESTERN BLOTTING;

ALANINE; ANTIBODIES, MONOCLONAL; BINDING SITES; CALCIUM; CROSS-LINKING REAGENTS; FACTOR VIII; FACTOR X; FACTOR XA; HEPARIN; HUMANS; KINETICS; LYSINE; MUTAGENESIS; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4043069944     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405537200     Document Type: Article

References (32)

1. Mann, K. G., Nesheim, M. E., Church, W. R., Haley, P., and Krishnaswamy, S. (1990) Blood 76, 1-16
2. Wood, W. I., Capon, D. J., Simonsen, C. C., Eaton, D. L., Gitschier, J., Keyt, B., Seeburg, P. H., Smith, D. H., Hollingshead, P., Wion, K. L., Delwart, E., Tuddenham, E. D. G., Vehar, G. A., and Lawn, R. M. (1984) Nature 312, 330-337
3. Vehar, G. A., Keyt, B., Eaton, D., Rodriguez, H., O'Brien, D. P., Rotblat, F., Oppermann, H., Keck, R., Wood, W. I., Harkins, R. N., Tuddenham, E. G. D., Lawn, R. M., and Capon, D. J. (1984) Nature 312, 337-342
4. Fay, P. J., Anderson, M. T., Chavin, S. I., and Marder, V. J. (1986) Biochim. Biophys. Acta 871, 268-278
5. Eaton, D., Rodriguez, H., and Vehar, G. A. (1986) Biochemistry 25, 505-512
6. Fay, P. J. (2004) Blood Rev. 18, 1-15
7. Fay, P. J., Mastri, M., Koszelak, M. E., and Wakabayashi, H. (2001) J. Biol. Chem. 276, 12434-12439
8. Lollar, P., Hill-Eubanks, D. C., and Parker, C. G. (1988) J. Biol. Chem. 263, 10451-10455
9. Regan, L. M., and Fay, P. J. (1995) J. Biol. Chem. 270, 8546-8552
10. Donath, M. S., Lenting, P. J., van Mourik, J. A., and Mertens, K. (1995) J. Biol. Chem. 270, 3648-3655
11. Nogami, K., Wakabayashi, H., and Fay, P. J. (2003) J. Biol. Chem. 278, 16502-16509
12. Koszelak Rosenblum, M. E., Schmidt, K., Freas, J., Mastri, M., and Fay, P. J. (2002) J. Biol. Chem. 277, 11664-11669
13. Nogami, K., Wakabayashi, H., Schmidt, K., and Fay, P. J. (2003) J. Biol. Chem. 278, 1634-1641
14. Lapan, K. A., and Fay, P. J. (1997) J. Biol. Chem. 272, 2082-2088
15. Lamphear, B. J., and Fay, P. J. (1992) Blood 80, 3120-3126
16. Nogami, K., Shima, M., Hosokawa, K., Suzuki, T., Koide, T., Saenko, E. L., Scandella, D., Shibata, M., Kamisue, S., Tanaka, I., and Yoshioka, A. (1999) J. Biol. Chem. 274, 31000-31007
17. Nogami, K., Lapan, K. A., Zhou, Q., Wakabayashi, H., and Fay, P. J. (2004) J. Biol. Chem. 279, 15763-15771
18. Rezaie, A. R. (2000) J. Biol. Chem. 275, 3320-3327
19. O'Brien, L. M., Huggins, C. F., and Fay, P. J. (1997) Blood 90, 3943-3950
20. Foster, P. A., Fulcher, C. A., Houghten, R. A., de Graaf Mahoney, S., and Zimmerman, T. S. (1988) J. Clin. Invest. 82, 123-128
21. Mimms, L. T., Zampighi, G., Nozaki, Y., Tanford, C., and Reynolds, J. A. (1981) Biochemistry 20, 833-840
22. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
23. Chen, L., Manithody, C., Yang, L., and Rezaie, A. R. (2004) Protein Sci. 13, 431-442
24. Rezaie, A. R., Neuenschwander, P. F., Morrissey, J. H., and Esmon, C. T. (1993) J. Biol. Chem. 268, 8176-8180
25. Lollar, P., Fay, P. J., and Fass, D. N. (1993) Methods Enzymol. 222, 128-143
26. Laemmli, U. K. (1970) Nature 227, 680-685
27. Lapan, K. A., and Fay, P. J. (1998) Thromb. Haemostasis 80, 418-422
28. Anderson, P. J., Nesset, A., Dharmawardana, K. R., and Bock, P. E. (2000) J. Biol. Chem. 275, 16428-16434
29. Rezaie, A. R. (1998) J. Biol. Chem. 273, 16824-16827
30. Betz, A., Hofsteenge, J., and Stone, S. R. (1991) Biochemistry 30, 9848-9853
31. Karshikov, A., Bode, W., Tulinsky, A., and Stone, S. R. (1992) Protein Sci. 1, 727-735
32. Myles, T., Le Bonniec, B., Betz, A., and Stone, S. R. (2001) Biochemistry 40, 4972-4979