Mechanisms of factor Xa-catalyzed cleavage of the factor VIIIa A1 subunit resulting in cofactor inactivation

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 16502-16509

  Nogami, Keiji ^a   Wakabayashi, Hironao ^a   Fay, Philip J ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CHEMICAL ACTIVATION; PROTEINS;

PROTEOLYSIS;

BIOCHEMICAL ENGINEERING;

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 8A; HEPARIN; MONOCLONAL ANTIBODY; PHOSPHOLIPID; PLASMA PROTEIN; RECOMBINANT BLOOD CLOTTING FACTOR 8; SYNTHETIC PEPTIDE; RECOMBINANT PROTEIN;

BINDING SITE; BLOOD CLOTTING; CATALYSIS; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME SUBUNIT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; WESTERN BLOTTING; ARTICLE; CHEMISTRY; HUMAN; HYDROLYSIS; KINETICS; METABOLISM;

BLOOD COAGULATION; FACTOR VIIIA; FACTOR XA; HUMANS; HYDROLYSIS; KINETICS; RECOMBINANT PROTEINS;

EID: 0037593891     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213044200     Document Type: Conference Paper

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