메뉴 건너뛰기




Volumn 9, Issue 1, 2010, Pages 32-37

Vitamin D: Proteases, protease inhibitors and cancer

Author keywords

Cancer; Cystatins; Protease inhibitors; Proteases; Proteasome; Ubiquitin; Vitamin D

Indexed keywords

BORTEZOMIB; CALCITRIOL; CYSTATIN; CYSTATIN D; MATRIX METALLOPROTEINASE; PROTEINASE INHIBITOR; SEOCALCITOL; SERINE PROTEINASE; UNCLASSIFIED DRUG; VITAMIN D;

EID: 74549186671     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.1.10266     Document Type: Review
Times cited : (34)

References (44)
  • 1
    • 57649155302 scopus 로고    scopus 로고
    • Proteases: Multifunctional enzymes in life and disease
    • López-Otín C, Bond JS. Proteases: multifunctional enzymes in life and disease. J Biol Chem 2008; 283:30433-7.
    • (2008) J Biol Chem , vol.283 , pp. 30433-30437
    • López-Otín, C.1    Bond, J.S.2
  • 2
    • 34648815810 scopus 로고    scopus 로고
    • Emerging roles of proteases in tumour suppression
    • López-Otín C, Matrisian LM. Emerging roles of proteases in tumour suppression. Nat Rev Cancer 2007; 7:800-8.
    • (2007) Nat Rev Cancer , vol.7 , pp. 800-808
    • López-Otín, C.1    Matrisian, L.M.2
  • 3
    • 0030918546 scopus 로고    scopus 로고
    • Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors
    • Turk B, Turk V, Turk D. Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors. Biol Chem 1997; 378:141-50.
    • (1997) Biol Chem , vol.378 , pp. 141-150
    • Turk, B.1    Turk, V.2    Turk, D.3
  • 5
    • 27244441777 scopus 로고    scopus 로고
    • Global approaches to understanding ubiquitination
    • Kaiser P, Huang L. Global approaches to understanding ubiquitination. Genome Biol 2005; 6:233.
    • (2005) Genome Biol , vol.6 , pp. 233
    • Kaiser, P.1    Huang, L.2
  • 6
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges D, Zwickl P, Baumeister W. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 1999; 68:1015-68.
    • (1999) Annu Rev Biochem , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 7
    • 8144222388 scopus 로고    scopus 로고
    • The emerging roles of human tissue kallikreins in cancer
    • Borgono CA, Diamandis EP. The emerging roles of human tissue kallikreins in cancer. Nat Rev Cancer 2004; 4:876-90.
    • (2004) Nat Rev Cancer , vol.4 , pp. 876-890
    • Borgono, C.A.1    Diamandis, E.P.2
  • 8
    • 33749017931 scopus 로고    scopus 로고
    • Cysteine cathepsins: Multifunctional enzymes in cancer
    • Mohamed MM, Sloane BF. Cysteine cathepsins: multifunctional enzymes in cancer. Nat Rev Cancer 2006; 6:764-75.
    • (2006) Nat Rev Cancer , vol.6 , pp. 764-775
    • Mohamed, M.M.1    Sloane, B.F.2
  • 9
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002; 2:161-74.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 12
    • 34548202165 scopus 로고    scopus 로고
    • Vitamin D signalling pathways in cancer: Potential for anticancer therapeutics
    • Deeb KK, Trump DL, Johnson CS. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer 2007; 7:684-700.
    • (2007) Nat Rev Cancer , vol.7 , pp. 684-700
    • Deeb, K.K.1    Trump, D.L.2    Johnson, C.S.3
  • 15
    • 66749105045 scopus 로고    scopus 로고
    • Nuclear receptors: Genomic and non-genomic effects converge
    • Ordóñez-Morán P, Muñoz A. Nuclear receptors: genomic and non-genomic effects converge. Cell Cycle 2009; 8:1675-80.
    • (2009) Cell Cycle , vol.8 , pp. 1675-1680
    • Ordóñez-Morán, P.1    Muñoz, A.2
  • 16
    • 0037224484 scopus 로고    scopus 로고
    • Nongenomic actions of steroid hormones
    • Losel R, Wehling M. Nongenomic actions of steroid hormones. Nat Rev Mol Cell Biol 2003; 4:46-56.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 46-56
    • Losel, R.1    Wehling, M.2
  • 17
    • 58149186769 scopus 로고    scopus 로고
    • RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype and Wnt pathway in colon cancer cells
    • Ordóñez-Morán P, Larriba MJ, Pálmer HG, Valero RA, Barbáchano A, Dunach M, et al. RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype and Wnt pathway in colon cancer cells. J Cell Biol 2008; 183:697-710.
    • (2008) J Cell Biol , vol.183 , pp. 697-710
    • Ordóñez-Morán, P.1    Larriba, M.J.2    Pálmer, H.G.3    Valero, R.A.4    Barbáchano, A.5    Dunach, M.6
  • 18
    • 68549094357 scopus 로고    scopus 로고
    • A genomic perspective on vitamin D signaling
    • Carlberg C, Seuter S. A genomic perspective on vitamin D signaling. Anticancer Res 2009; 29:3485-93.
    • (2009) Anticancer Res , vol.29 , pp. 3485-3493
    • Carlberg, C.1    Seuter, S.2
  • 19
    • 0034976117 scopus 로고    scopus 로고
    • Regulation of gene expression by 1á,25-dihydroxyvitamin D3 and its analog EB1089 under growth-inhibitory conditions in squamous carcinoma cells
    • Akutsu N, Lin R, Bastien Y, Bestawros A, Enepekides DJ, Black MJ, White JH. Regulation of gene expression by 1á,25-dihydroxyvitamin D3 and its analog EB1089 under growth-inhibitory conditions in squamous carcinoma cells. Mol Endocrinol 2001; 15:1127-39.
    • (2001) Mol Endocrinol , vol.15 , pp. 1127-1139
    • Akutsu, N.1    Lin, R.2    Bastien, Y.3    Bestawros, A.4    Enepekides, D.J.5    Black, M.J.6    White, J.H.7
  • 20
    • 85047681364 scopus 로고    scopus 로고
    • Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation
    • Lin R, Nagai Y, Sladek R, Bastien Y, Ho J, Petrecca K, et al. Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation. Mol Endocrinol 2002; 16:1243-56.
    • (2002) Mol Endocrinol , vol.16 , pp. 1243-1256
    • Lin, R.1    Nagai, Y.2    Sladek, R.3    Bastien, Y.4    Ho, J.5    Petrecca, K.6
  • 21
    • 0036046405 scopus 로고    scopus 로고
    • Gene expression analysis of 1,25(OH)2D3-dependent differentiation of HL-60 cells: A cDNA array study
    • Savli H, Aalto Y, Nagy B, Knuutila S, Pakkala S. Gene expression analysis of 1,25(OH)2D3-dependent differentiation of HL-60 cells: a cDNA array study. Br J Haematol 2002; 118:1065-70.
    • (2002) Br J Haematol , vol.118 , pp. 1065-1070
    • Savli, H.1    Aalto, Y.2    Nagy, B.3    Knuutila, S.4    Pakkala, S.5
  • 23
    • 0037485699 scopus 로고    scopus 로고
    • Vitamin D growth inhibition of breast cancer cells: Gene expression patterns assessed by cDNA microarray
    • Swami S, Raghavachari N, Muller UR, Bao YP, Feldman D. Vitamin D growth inhibition of breast cancer cells: gene expression patterns assessed by cDNA microarray. Breast Cancer Res Treat 2003; 80:49-62.
    • (2003) Breast Cancer Res Treat , vol.80 , pp. 49-62
    • Swami, S.1    Raghavachari, N.2    Muller, U.R.3    Bao, Y.P.4    Feldman, D.5
  • 24
    • 1942443627 scopus 로고    scopus 로고
    • Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays
    • Krishnan AV, Shinghal R, Raghavachari N, Brooks JD, Peehl DM, Feldman D. Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays. Prostate 2004; 59:243-51.
    • (2004) Prostate , vol.59 , pp. 243-251
    • Krishnan, A.V.1    Shinghal, R.2    Raghavachari, N.3    Brooks, J.D.4    Peehl, D.M.5    Feldman, D.6
  • 25
    • 27444435423 scopus 로고    scopus 로고
    • Suppression of death receptor-mediated apoptosis by 1,25-dihydroxyvitamin D3 revealed by microarray analysis
    • Zhang X, Li P, Bao J, Nicosia SV, Wang H, Enkemann SA, Bai W. Suppression of death receptor-mediated apoptosis by 1,25-dihydroxyvitamin D3 revealed by microarray analysis. J Biol Chem 2005; 280:35458-68.
    • (2005) J Biol Chem , vol.280 , pp. 35458-35468
    • Zhang, X.1    Li, P.2    Bao, J.3    Nicosia, S.V.4    Wang, H.5    Enkemann, S.A.6    Bai, W.7
  • 26
    • 68849107323 scopus 로고    scopus 로고
    • Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells
    • Alvarez-Díaz S, Valle N, García JM, Peña C, Freije JM, Quesada V, et al. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. J Clin Invest 2009; 119:2343-58.
    • (2009) J Clin Invest , vol.119 , pp. 2343-2358
    • Alvarez-Díaz, S.1    Valle, N.2    García, J.M.3    Peña, C.4    Freije, J.M.5    Quesada, V.6
  • 27
    • 0028021728 scopus 로고
    • Structural and functional characterization of two allelic variants of human cystatin D sharing a characteristic inhibition spectrum against mammalian cysteine proteinases
    • Balbín M, Hall A, Grubb A, Mason RW, López-Otín C, Abrahamson M. Structural and functional characterization of two allelic variants of human cystatin D sharing a characteristic inhibition spectrum against mammalian cysteine proteinases. J Biol Chem 1994; 269:23156-62.
    • (1994) J Biol Chem , vol.269 , pp. 23156-23162
    • Balbín, M.1    Hall, A.2    Grubb, A.3    Mason, R.W.4    López-Otín, C.5    Abrahamson, M.6
  • 28
    • 0025757378 scopus 로고
    • Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor
    • Freije JP, Abrahamson M, Olafsson I, Velasco G, Grubb A, López-Otín C. Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor. J Biol Chem 1991; 266:20538-43.
    • (1991) J Biol Chem , vol.266 , pp. 20538-20543
    • Freije, J.P.1    Abrahamson, M.2    Olafsson, I.3    Velasco, G.4    Grubb, A.5    López-Otín, C.6
  • 29
    • 4944252978 scopus 로고    scopus 로고
    • Cystatin m: A novel candidate tumor suppressor gene for breast cancer
    • Zhang J, Shridhar R, Dai Q, Song J, Barlow SC, Yin L, et al. Cystatin m: a novel candidate tumor suppressor gene for breast cancer. Cancer Res 2004; 64:6957-64.
    • (2004) Cancer Res , vol.64 , pp. 6957-6964
    • Zhang, J.1    Shridhar, R.2    Dai, Q.3    Song, J.4    Barlow, S.C.5    Yin, L.6
  • 32
    • 0038389309 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D(3) increases human cystatin A expression by inhibiting the Raf-1/MEK1/ERK signaling pathway of keratinocytes
    • Takahashi H, Ibe M, Honma M, Ishida-Yamamoto A, Hashimoto Y, Iizuka H. 1,25-dihydroxyvitamin D(3) increases human cystatin A expression by inhibiting the Raf-1/MEK1/ERK signaling pathway of keratinocytes. Arch Dermatol Res 2003; 295:80-7.
    • (2003) Arch Dermatol Res , vol.295 , pp. 80-87
    • Takahashi, H.1    Ibe, M.2    Honma, M.3    Ishida-Yamamoto, A.4    Hashimoto, Y.5    Iizuka, H.6
  • 33
    • 0030200377 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 induces morphological and biochemical markers of apoptosis in MCF-7 breast cancer cells
    • Simboli-Campbell M, Narvaez CJ, Tenniswood M, Welsh J. 1,25-Dihydroxyvitamin D3 induces morphological and biochemical markers of apoptosis in MCF-7 breast cancer cells. J Steroid Biochem Mol Biol 1996; 58:367-76.
    • (1996) J Steroid Biochem Mol Biol , vol.58 , pp. 367-376
    • Simboli-Campbell, M.1    Narvaez, C.J.2    Tenniswood, M.3    Welsh, J.4
  • 34
    • 0035947776 scopus 로고    scopus 로고
    • Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
    • Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, et al. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001; 153:999-1010.
    • (2001) J Cell Biol , vol.153 , pp. 999-1010
    • Foghsgaard, L.1    Wissing, D.2    Mauch, D.3    Lademann, U.4    Bastholm, L.5    Boes, M.6
  • 35
    • 0033756474 scopus 로고    scopus 로고
    • Cathepsin B contributes to TNFalpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
    • Guicciardi ME, Deussing J, Miyoshi H, Bronk SF, Svingen PA, Peters C, et al. Cathepsin B contributes to TNFalpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest 2000; 106:1127-37.
    • (2000) J Clin Invest , vol.106 , pp. 1127-1137
    • Guicciardi, M.E.1    Deussing, J.2    Miyoshi, H.3    Bronk, S.F.4    Svingen, P.A.5    Peters, C.6
  • 36
    • 0027946430 scopus 로고    scopus 로고
    • Guenette RS, Mooibroek M, Wong K, Wong P, Tenniswood M. Cathepsin B, a cysteine protease implicated in metastatic progression, is also expressed during regression of the rat prostate and mammary glands. Eur J Biochem 1994; 226:311-21.
    • Guenette RS, Mooibroek M, Wong K, Wong P, Tenniswood M. Cathepsin B, a cysteine protease implicated in metastatic progression, is also expressed during regression of the rat prostate and mammary glands. Eur J Biochem 1994; 226:311-21.
  • 37
    • 33947114372 scopus 로고    scopus 로고
    • Identification of novel mediators of Vitamin D signaling and 1,25(OH)2D3 resistance in mammary cells
    • Byrne B, Welsh J. Identification of novel mediators of Vitamin D signaling and 1,25(OH)2D3 resistance in mammary cells. J Steroid Biochem Mol Biol 2007; 103:703-7.
    • (2007) J Steroid Biochem Mol Biol , vol.103 , pp. 703-707
    • Byrne, B.1    Welsh, J.2
  • 38
    • 0035879752 scopus 로고    scopus 로고
    • Sensitization to TNF-induced apoptosis by 1,25-dihydroxy vitamin D(3) involves upregulation of the TNF receptor 1 and cathepsin B
    • Mathiasen IS, Hansen CM, Foghsgaard L, Jaattela M. Sensitization to TNF-induced apoptosis by 1,25-dihydroxy vitamin D(3) involves upregulation of the TNF receptor 1 and cathepsin B. Int J Cancer 2001; 93:224-31.
    • (2001) Int J Cancer , vol.93 , pp. 224-231
    • Mathiasen, I.S.1    Hansen, C.M.2    Foghsgaard, L.3    Jaattela, M.4
  • 39
    • 0033625046 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 and its analogues downregulate cell invasionassociated proteases in cultured malignant cells
    • Koli K, Keski-Oja J. 1alpha,25-dihydroxyvitamin D3 and its analogues downregulate cell invasionassociated proteases in cultured malignant cells. Cell Growth Differ 2000; 11:221-9.
    • (2000) Cell Growth Differ , vol.11 , pp. 221-229
    • Koli, K.1    Keski-Oja, J.2
  • 40
    • 29744463149 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 inhibits prostate cancer cell invasion via modulation of selective proteases
    • Bao BY, Yeh SD, Lee YF. 1alpha,25-dihydroxyvitamin D3 inhibits prostate cancer cell invasion via modulation of selective proteases. Carcinogenesis 2006; 27:32-42.
    • (2006) Carcinogenesis , vol.27 , pp. 32-42
    • Bao, B.Y.1    Yeh, S.D.2    Lee, Y.F.3
  • 41
    • 19344371357 scopus 로고    scopus 로고
    • Human tissue kallikrein gene family: Applications in cancer
    • Obiezu CV, Diamandis EP. Human tissue kallikrein gene family: applications in cancer. Cancer Lett 2005; 224:1-22.
    • (2005) Cancer Lett , vol.224 , pp. 1-22
    • Obiezu, C.V.1    Diamandis, E.P.2
  • 42
    • 33947224164 scopus 로고    scopus 로고
    • Human tissue kallikreins: The cancer biomarker family
    • Paliouras M, Borgono C, Diamandis EP. Human tissue kallikreins: the cancer biomarker family. Cancer Lett 2007; 249:61-79.
    • (2007) Cancer Lett , vol.249 , pp. 61-79
    • Paliouras, M.1    Borgono, C.2    Diamandis, E.P.3
  • 43
    • 74549153376 scopus 로고    scopus 로고
    • The Ubiquitin-Proteasome System in cancer, a major player in DNA Repair. Part 1: Posttranslational regulation
    • Vlachostergios PJ, Patrikidou A, Daliani DD, Papandreou CN. The Ubiquitin-Proteasome System in cancer, a major player in DNA Repair. Part 1: Posttranslational regulation. J Cell Mol Med 2009.
    • (2009) J Cell Mol Med
    • Vlachostergios, P.J.1    Patrikidou, A.2    Daliani, D.D.3    Papandreou, C.N.4
  • 44
    • 66749083491 scopus 로고    scopus 로고
    • DUBs and cancer: The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors
    • Hussain S, Zhang Y, Galardy PJ. DUBs and cancer: the role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors. Cell Cycle 2009; 8:1688-97.
    • (2009) Cell Cycle , vol.8 , pp. 1688-1697
    • Hussain, S.1    Zhang, Y.2    Galardy, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.