Functionalized chalcones with basic functionalities have antibacterial activity against drug sensitive Staphylococcus aureus

European Journal of Medicinal Chemistry

Volumn 43, Issue 8, 2008, Pages 1681-1687

  Liu, X L ^a   Xu, Y J ^b   Go, M L ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b SCHOOL OF ENGINEERING   (Singapore)

Author keywords

Antibacterial activity; Basic substituents; Chalcones; Protection against hemolysis; Structure activity relationship

Indexed keywords

1 (2 HYDROXY 4,6 DIMETHOXY 3 (1 METHYLPIPERIDIN 4 YL)PHENYL 3 (3 CHLOROPHENYL)PROP 2 EN 1 ONE; 1 (2 HYDROXY 4,6 DIMETHOXY 3 (1 METHYLPIPERIDIN 4 YL)PHENYL 3 (4 METHYLPHENYL)PROP 2 EN 1 ONE; CHALCONE DERIVATIVE; LICOCHALCONE A; PENICILLIN G; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; ERYTHROCYTE; ESCHERICHIA COLI; HEMOLYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS; TOXICITY;

ANTI-BACTERIAL AGENTS; CHALCONE; MOLECULAR STRUCTURE; SENSITIVITY AND SPECIFICITY; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 47949126241     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.10.007     Document Type: Article

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