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Volumn 63, Issue 1, 2010, Pages 4-11

Fusion genes in epithelial neoplasia

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; HIGH MOBILITY GROUP A2 PROTEIN; NTRK1 TYROSIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 1; PROTEIN RET; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR ETV6; UNCLASSIFIED DRUG;

EID: 74049110546     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2009.068759     Document Type: Review
Times cited : (7)

References (87)
  • 1
    • 1842535882 scopus 로고    scopus 로고
    • Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
    • Mitelman F, Johansson B, Mertens F. Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat Genet 2004;36:331-4.
    • (2004) Nat Genet , vol.36 , pp. 331-334
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 2
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman F, Johansson B, Mertens F. The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 2007;7:233- 45.
    • (2007) Nat Rev Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 3
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005;310:644-8.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 4
    • 33845255290 scopus 로고    scopus 로고
    • Santoro M, Melillo RM, Fusco A. RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture. Eur J Endocrinol 2006;155:645-53.
    • Santoro M, Melillo RM, Fusco A. RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture. Eur J Endocrinol 2006;155:645-53.
  • 6
    • 34547819754 scopus 로고    scopus 로고
    • HOOK3-RET: A novel type of RET/PTC rearrangement in papillary thyroid carcinoma
    • Ciampi R, Giordano TJ, Wikenheiser-Brokamp K, et al. HOOK3-RET: a novel type of RET/PTC rearrangement in papillary thyroid carcinoma. Endocr Relat Cancer 2007;14:445-52.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 445-452
    • Ciampi, R.1    Giordano, T.J.2    Wikenheiser-Brokamp, K.3
  • 7
    • 0035986363 scopus 로고    scopus 로고
    • RET/PTC rearrangement in thyroid tumors
    • Nikiforov YE. RET/PTC rearrangement in thyroid tumors. Endocr Pathol 2002;13:3-16.
    • (2002) Endocr Pathol , vol.13 , pp. 3-16
    • Nikiforov, Y.E.1
  • 8
    • 33645232222 scopus 로고    scopus 로고
    • Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas
    • Adeniran AJ, Zhu Z, Gandhi M, et al. Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas. Am J Surg Pathol 2006;30:216-22.
    • (2006) Am J Surg Pathol , vol.30 , pp. 216-222
    • Adeniran, A.J.1    Zhu, Z.2    Gandhi, M.3
  • 9
    • 0030941779 scopus 로고    scopus 로고
    • Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children
    • Nikiforov YE, Rowland JM, Bove KE, et al. Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children. Cancer Res 1997;57:1690-4.
    • (1997) Cancer Res , vol.57 , pp. 1690-1694
    • Nikiforov, Y.E.1    Rowland, J.M.2    Bove, K.E.3
  • 10
    • 18244390747 scopus 로고    scopus 로고
    • RET activation and clinicopathologic features in poorly differentiated thyroid tumors
    • Santoro M, Papotti M, Chiappetta G, et al. RET activation and clinicopathologic features in poorly differentiated thyroid tumors. J Clin Endocrinol Metab 2002;87:370-9.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 370-379
    • Santoro, M.1    Papotti, M.2    Chiappetta, G.3
  • 11
    • 0031933680 scopus 로고    scopus 로고
    • RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes
    • Tallini G, Santoro M, Helie M, et al. RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes. Clin Cancer Res 1998;4:287-94.
    • (1998) Clin Cancer Res , vol.4 , pp. 287-294
    • Tallini, G.1    Santoro, M.2    Helie, M.3
  • 12
    • 0034613291 scopus 로고    scopus 로고
    • Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells
    • Nikiforova MN, Stringer JR, Blough R, et al. Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. Science 2000;290:138-41.
    • (2000) Science , vol.290 , pp. 138-141
    • Nikiforova, M.N.1    Stringer, J.R.2    Blough, R.3
  • 13
    • 85047691154 scopus 로고    scopus 로고
    • Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
    • Ciampi R, Knauf JA, Kerler R, et al. Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. J Clin Invest 2005;115:94-101.
    • (2005) J Clin Invest , vol.115 , pp. 94-101
    • Ciampi, R.1    Knauf, J.A.2    Kerler, R.3
  • 14
    • 28044443680 scopus 로고    scopus 로고
    • Alterations of the BRAF gene in thyroid tumors
    • Ciampi R, Nikiforov YE. Alterations of the BRAF gene in thyroid tumors. Endocr Pathol 2005;16:163-72.
    • (2005) Endocr Pathol , vol.16 , pp. 163-172
    • Ciampi, R.1    Nikiforov, Y.E.2
  • 15
    • 59449089240 scopus 로고    scopus 로고
    • High rate of BRAF and RET/ PTC dual mutations associated with recurrent papillary thyroid carcinoma
    • Henderson YC, Shellenberger TD, Williams MD, et al. High rate of BRAF and RET/ PTC dual mutations associated with recurrent papillary thyroid carcinoma. Clin Cancer Res 2009;15:485-91.
    • (2009) Clin Cancer Res , vol.15 , pp. 485-491
    • Henderson, Y.C.1    Shellenberger, T.D.2    Williams, M.D.3
  • 16
    • 0034714190 scopus 로고    scopus 로고
    • PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]
    • Kroll TG, Sarraf P, Pecciarini L, et al. PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]. Science 2000;289:1357-60.
    • (2000) Science , vol.289 , pp. 1357-1360
    • Kroll, T.G.1    Sarraf, P.2    Pecciarini, L.3
  • 17
    • 0031777309 scopus 로고    scopus 로고
    • Follicular cells of the thyroid gland require Pax8 gene function
    • Mansouri A, Chowdhury K, Gruss P. Follicular cells of the thyroid gland require Pax8 gene function. Nat Genet 1998;19:87-90.
    • (1998) Nat Genet , vol.19 , pp. 87-90
    • Mansouri, A.1    Chowdhury, K.2    Gruss, P.3
  • 18
    • 0032867442 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: A family of lipid-activated transcription factors
    • Clarke SD, Thuillier P, Baillie RA, et al. Peroxisome proliferator-activated receptors: a family of lipid-activated transcription factors. Am J Clin Nutr 1999;70:566-71.
    • (1999) Am J Clin Nutr , vol.70 , pp. 566-571
    • Clarke, S.D.1    Thuillier, P.2    Baillie, R.A.3
  • 19
    • 0036344885 scopus 로고    scopus 로고
    • Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas
    • Marques AR, Espadinha C, Catarino AL, et al. Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas. J Clin Endocrinol Metab 2002;87:3947-52.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3947-3952
    • Marques, A.R.1    Espadinha, C.2    Catarino, A.L.3
  • 20
    • 0037238701 scopus 로고    scopus 로고
    • Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas
    • Cheung L, Messina M, Gill A, et al. Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas. J Clin Endocrinol Metab 2003;88:354-7.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 354-357
    • Cheung, L.1    Messina, M.2    Gill, A.3
  • 21
    • 0035984201 scopus 로고    scopus 로고
    • PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses
    • Nikiforova MN, Biddinger PW, Caudill CM, et al. PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses. Am J Surg Pathol 2002;26:1016-23.
    • (2002) Am J Surg Pathol , vol.26 , pp. 1016-1023
    • Nikiforova, M.N.1    Biddinger, P.W.2    Caudill, C.M.3
  • 22
    • 30344476973 scopus 로고    scopus 로고
    • PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma
    • Castro P, Rebocho AP, Soares RJ, et al. PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma. J Clin Endocrinol Metab 2006;91:213-20.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 213-220
    • Castro, P.1    Rebocho, A.P.2    Soares, R.J.3
  • 23
    • 52049095050 scopus 로고    scopus 로고
    • CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis
    • Lui WO, Zeng L, Rehrmann V, et al. CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis. Cancer Res 2008;68:7156-64.
    • (2008) Cancer Res , vol.68 , pp. 7156-7164
    • Lui, W.O.1    Zeng, L.2    Rehrmann, V.3
  • 24
    • 0031038873 scopus 로고    scopus 로고
    • Promoter swapping between the genes for a novel zinc finger protein and b-catenin in pleomorphic adenomas with t(3;8)(p21;q12) translocations
    • Kas K, Voz ML, Roijer E, et al. Promoter swapping between the genes for a novel zinc finger protein and b-catenin in pleomorphic adenomas with t(3;8)(p21;q12) translocations. Nat Genet 1997;15:170-4.
    • (1997) Nat Genet , vol.15 , pp. 170-174
    • Kas, K.1    Voz, M.L.2    Roijer, E.3
  • 25
    • 0032546234 scopus 로고    scopus 로고
    • The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter
    • Voz ML, Astrom AK, Kas K, et al. The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter. Oncogene 1998;16:1409-6.
    • (1998) Oncogene , vol.16 , pp. 1409-1416
    • Voz, M.L.1    Astrom, A.K.2    Kas, K.3
  • 26
    • 2542508022 scopus 로고    scopus 로고
    • Conserved mechanism of PLAG1 activation in salivary gland tumors with and without chromosome 8q12 abnormalities: Identification of SII as a new fusion partner gene
    • Astrom AK, Voz ML, Kas K, et al. Conserved mechanism of PLAG1 activation in salivary gland tumors with and without chromosome 8q12 abnormalities: identification of SII as a new fusion partner gene. Cancer Res 1999;59:918-23.
    • (1999) Cancer Res , vol.59 , pp. 918-923
    • Astrom, A.K.1    Voz, M.L.2    Kas, K.3
  • 27
    • 33746816237 scopus 로고    scopus 로고
    • CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas
    • Asp J, Persson F, Kost-Alimova M, et al. CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas. Genes Chromosomes Cancer 2006;45:820-8.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 820-828
    • Asp, J.1    Persson, F.2    Kost-Alimova, M.3
  • 28
    • 34250875866 scopus 로고    scopus 로고
    • Advances in salivary gland pathology
    • Cheuk W, Chan JK. Advances in salivary gland pathology. Histopathology 2007;51:1-20.
    • (2007) Histopathology , vol.51 , pp. 1-20
    • Cheuk, W.1    Chan, J.K.2
  • 29
    • 33846512789 scopus 로고    scopus 로고
    • WIF1, an inhibitor of the Wnt pathway, is rearranged in salivary gland tumors
    • Queimado L, Lopes CS, Reis AM. WIF1, an inhibitor of the Wnt pathway, is rearranged in salivary gland tumors. Genes Chromosomes Cancer 2007;46:215-25.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 215-225
    • Queimado, L.1    Lopes, C.S.2    Reis, A.M.3
  • 30
    • 58149389526 scopus 로고    scopus 로고
    • High-resolution genomic profiling of adenomas and carcinomas of the salivary glands reveals amplification, rearrangement, and fusion of HMGA2
    • Persson F, Andrén Y, Winnes M, et al. High-resolution genomic profiling of adenomas and carcinomas of the salivary glands reveals amplification, rearrangement, and fusion of HMGA2. Genes Chromosomes Cancer 2009;48:69-82.
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 69-82
    • Persson, F.1    Andrén, Y.2    Winnes, M.3
  • 31
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007;315:1576-9.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 32
    • 33645826528 scopus 로고    scopus 로고
    • Molecular classification of mucoepidermoid carcinomas-prognostic significance of the MECT1-MAML2 fusion oncogene
    • Behboudi A, Enlund F, Winnes M, et al. Molecular classification of mucoepidermoid carcinomas-prognostic significance of the MECT1-MAML2 fusion oncogene. Genes Chromosomes Cancer 2006;45:470-81.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 470-481
    • Behboudi, A.1    Enlund, F.2    Winnes, M.3
  • 33
    • 0037313331 scopus 로고    scopus 로고
    • t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
    • Tonon G, Modi S, Wu L, et al. t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nat Genet 2003;33:208-13.
    • (2003) Nat Genet , vol.33 , pp. 208-213
    • Tonon, G.1    Modi, S.2    Wu, L.3
  • 34
    • 0141922981 scopus 로고    scopus 로고
    • TORCs: Transducers of regulated CREB activity
    • Conkright MD, Canettieri G, Screaton R, et al. TORCs: transducers of regulated CREB activity. Mol Cell 2003;12:413-23.
    • (2003) Mol Cell , vol.12 , pp. 413-423
    • Conkright, M.D.1    Canettieri, G.2    Screaton, R.3
  • 35
    • 0036837899 scopus 로고    scopus 로고
    • Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors
    • Wu L, Sun T, Kobayashi K, et al. Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. Mol Cell Biol 2002;22:7688-700.
    • (2002) Mol Cell Biol , vol.22 , pp. 7688-7700
    • Wu, L.1    Sun, T.2    Kobayashi, K.3
  • 36
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray SJ. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 2006;7:678-89.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 37
    • 23844523415 scopus 로고    scopus 로고
    • Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes
    • Coxon A, Rozenblum E, Park YS, et al. Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes. Cancer Res 2005;65:7137-44.
    • (2005) Cancer Res , vol.65 , pp. 7137-7144
    • Coxon, A.1    Rozenblum, E.2    Park, Y.S.3
  • 38
    • 22744458562 scopus 로고    scopus 로고
    • Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation
    • Wu L, Liu J, Gao P, et al. Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation. EMBO J 2005;24:2391-402.
    • (2005) EMBO J , vol.24 , pp. 2391-2402
    • Wu, L.1    Liu, J.2    Gao, P.3
  • 39
    • 33746005602 scopus 로고    scopus 로고
    • The MECT1-MAML2 gene fusion and benign Warthin's tumor: Is the MECT1-MAML2 gene fusion specific to mucuepidermoid carcinoma?
    • Winnes M, Enlund F, Mark J, et al. The MECT1-MAML2 gene fusion and benign Warthin's tumor: is the MECT1-MAML2 gene fusion specific to mucuepidermoid carcinoma? J Mol Diagn 2006;8:394-5.
    • (2006) J Mol Diagn , vol.8 , pp. 394-395
    • Winnes, M.1    Enlund, F.2    Mark, J.3
  • 40
    • 17044384692 scopus 로고    scopus 로고
    • Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion
    • Behboudi A, Winnes M, Gorunova L, et al. Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion. Genes Chromosomes Cancer 2005;43:202-5.
    • (2005) Genes Chromosomes Cancer , vol.43 , pp. 202-205
    • Behboudi, A.1    Winnes, M.2    Gorunova, L.3
  • 41
    • 34247474279 scopus 로고    scopus 로고
    • Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas
    • Winnes M, Molne L, Suurkula M, et al. Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas. Genes Chromosomes Cancer 2007;46:559-63.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 559-563
    • Winnes, M.1    Molne, L.2    Suurkula, M.3
  • 42
    • 38549121686 scopus 로고    scopus 로고
    • A new type of MAML2 fusion in mucoepidermoid carcinoma
    • Fehr A, Roser K, Heidorn K, et al. A new type of MAML2 fusion in mucoepidermoid carcinoma. Genes Chromosomes Cancer 2008;47:203-6.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 203-206
    • Fehr, A.1    Roser, K.2    Heidorn, K.3
  • 43
    • 42949150065 scopus 로고    scopus 로고
    • POU5F1, encoding a key regulator of stem cell pluripotency, is fused to EWSR1 in hidradenoma of the skin and mucoepidermoid carcinoma of the salivary glands
    • Möller E, Stenman G, Mandahl N, et al. POU5F1, encoding a key regulator of stem cell pluripotency, is fused to EWSR1 in hidradenoma of the skin and mucoepidermoid carcinoma of the salivary glands. J Pathol 2008;215:78-86.
    • (2008) J Pathol , vol.215 , pp. 78-86
    • Möller, E.1    Stenman, G.2    Mandahl, N.3
  • 44
    • 0035446797 scopus 로고    scopus 로고
    • Upper respiratory tract carcinoma with chromosomal translocation 15;19: Evidence for a distinct disease entity of young patients with a rapidly fatal course
    • Vargas SO, French CA, Faul PN, et al. Upper respiratory tract carcinoma with chromosomal translocation 15;19: evidence for a distinct disease entity of young patients with a rapidly fatal course. Cancer 2001;92:1195-203.
    • (2001) Cancer , vol.92 , pp. 1195-1203
    • Vargas, S.O.1    French, C.A.2    Faul, P.N.3
  • 45
    • 0037439788 scopus 로고    scopus 로고
    • BRD4-NUT fusion oncogene: A novel mechanism in aggressive carcinoma
    • French CA, Miyoshi I, Kubonishi I, et al. BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma. Cancer Res 2003;63:304-7.
    • (2003) Cancer Res , vol.63 , pp. 304-307
    • French, C.A.1    Miyoshi, I.2    Kubonishi, I.3
  • 46
    • 0036724194 scopus 로고    scopus 로고
    • A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase
    • Maruyama T, Farina A, Dey A, et al. A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase. Mol Cell Biol 2002;22:6509-20.
    • (2002) Mol Cell Biol , vol.22 , pp. 6509-6520
    • Maruyama, T.1    Farina, A.2    Dey, A.3
  • 47
    • 42049095157 scopus 로고    scopus 로고
    • The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase
    • Mochizuki K, Nishiyama A, Jang MK, et al. The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase. J Biol Chem 2008;283:9040-8.
    • (2008) J Biol Chem , vol.283 , pp. 9040-9048
    • Mochizuki, K.1    Nishiyama, A.2    Jang, M.K.3
  • 48
    • 38549113034 scopus 로고    scopus 로고
    • Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression
    • Yang Z, He N, Zhou Q. Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression. Mol Cell Biol 2008;28:967-76.
    • (2008) Mol Cell Biol , vol.28 , pp. 967-976
    • Yang, Z.1    He, N.2    Zhou, Q.3
  • 49
    • 7044245866 scopus 로고    scopus 로고
    • Midline carcinoma of children and young adults with NUT rearrangement
    • French CA, Kutok JL, Faquin WC, et al. Midline carcinoma of children and young adults with NUT rearrangement. J Clin Oncol 2004;22:4135-9.
    • (2004) J Clin Oncol , vol.22 , pp. 4135-4139
    • French, C.A.1    Kutok, J.L.2    Faquin, W.C.3
  • 50
    • 41649120757 scopus 로고    scopus 로고
    • BRD-NUT oncoproteins: A family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells
    • French CA, Ramirez CL, Kolmakova J, et al. BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells. Oncogene 2008;27:2237-42.
    • (2008) Oncogene , vol.27 , pp. 2237-2242
    • French, C.A.1    Ramirez, C.L.2    Kolmakova, J.3
  • 51
    • 67649531792 scopus 로고    scopus 로고
    • Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody
    • Haack H, Johnson LA, Fry CJ, et al. Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody. Am J Surg Pathol 2009;33:984-91.
    • (2009) Am J Surg Pathol , vol.33 , pp. 984-991
    • Haack, H.1    Johnson, L.A.2    Fry, C.J.3
  • 52
    • 77953714098 scopus 로고    scopus 로고
    • Molecular pathology of NUT midline carcinomas
    • Published Online First: 13 June, doi:10.1136/jcp.2007. 052902
    • French CA. Molecular pathology of NUT midline carcinomas. J Clin Pathol. Published Online First: 13 June 2008. doi:10.1136/jcp.2007. 052902
    • (2008) J Clin Pathol
    • French, C.A.1
  • 53
    • 17444381939 scopus 로고    scopus 로고
    • Translocation carcinomas of the kidney
    • Argani P, Ladanyi M. Translocation carcinomas of the kidney. Clin Lab Med 2005;25:363-78.
    • (2005) Clin Lab Med , vol.25 , pp. 363-378
    • Argani, P.1    Ladanyi, M.2
  • 54
    • 0026077913 scopus 로고
    • The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22
    • Henthorn PS, Stewart CC, Kadesch T, et al. The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22. Genomics 1991;11:374-8.
    • (1991) Genomics , vol.11 , pp. 374-378
    • Henthorn, P.S.1    Stewart, C.C.2    Kadesch, T.3
  • 55
    • 0035804224 scopus 로고    scopus 로고
    • The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25
    • Ladanyi M, Lui MY, Antonescu CR, et al. The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25. Oncogene 2001;20:48-57.
    • (2001) Oncogene , vol.20 , pp. 48-57
    • Ladanyi, M.1    Lui, M.Y.2    Antonescu, C.R.3
  • 56
    • 33748338144 scopus 로고    scopus 로고
    • The evolving story of renal translocation carcinomas
    • Argani P. The evolving story of renal translocation carcinomas. Am J Clin Pathol 2006;126:332-4.
    • (2006) Am J Clin Pathol , vol.126 , pp. 332-334
    • Argani, P.1
  • 57
    • 0037501437 scopus 로고    scopus 로고
    • Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: A sensitive and specific immunohistochemical assay
    • Argani P, Lal P, Hutchinson B, et al. Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay. Am J Surg Pathol 2003;27:750- 61.
    • (2003) Am J Surg Pathol , vol.27 , pp. 750-761
    • Argani, P.1    Lal, P.2    Hutchinson, B.3
  • 58
    • 42649107487 scopus 로고    scopus 로고
    • Renal translocation carcinomas: Clinicopathologic, immunohistochemical, and gene expression profiling analysis of 31 cases with a review of the literature
    • Camparo P, Vasiliu V, Molinie V, et al. Renal translocation carcinomas: clinicopathologic, immunohistochemical, and gene expression profiling analysis of 31 cases with a review of the literature. Am J Surg Pathol 2008;32:656-70.
    • (2008) Am J Surg Pathol , vol.32 , pp. 656-670
    • Camparo, P.1    Vasiliu, V.2    Molinie, V.3
  • 59
    • 0037609538 scopus 로고    scopus 로고
    • Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation
    • Davis IJ, Hsi BL, Arroyo JD, et al. Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation. Proc Natl Acad Sci U S A 2003;100:6051-6.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6051-6056
    • Davis, I.J.1    Hsi, B.L.2    Arroyo, J.D.3
  • 60
    • 19944433827 scopus 로고    scopus 로고
    • Renal carcinomas with the t(6;11)(p21;q12): Clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR
    • Argani P, Lae M, Hutchinson B, et al. Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR. Am J Surg Pathol 2005;29:230-40.
    • (2005) Am J Surg Pathol , vol.29 , pp. 230-240
    • Argani, P.1    Lae, M.2    Hutchinson, B.3
  • 61
    • 33645741110 scopus 로고    scopus 로고
    • Translocation carcinomas of the kidney after chemotherapy in childhood
    • Argani P, Lae M, Ballard ET, et al. Translocation carcinomas of the kidney after chemotherapy in childhood. J Clin Oncol 2006;24:1529-34.
    • (2006) J Clin Oncol , vol.24 , pp. 1529-1534
    • Argani, P.1    Lae, M.2    Ballard, E.T.3
  • 62
    • 19044391610 scopus 로고    scopus 로고
    • Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
    • Tognon C, Knezevich SR, Huntsman D, et al. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell 2002;2:367-76.
    • (2002) Cancer Cell , vol.2 , pp. 367-376
    • Tognon, C.1    Knezevich, S.R.2    Huntsman, D.3
  • 63
    • 2342624760 scopus 로고    scopus 로고
    • A fluorescence in situ hybridization study of ETV6-NTRK3 fusion gene in secretory breast carcinoma
    • Makretsov N, He M, Hayes M, et al. A fluorescence in situ hybridization study of ETV6-NTRK3 fusion gene in secretory breast carcinoma. Genes Chromosomes Cancer 2004;40:152-7.
    • (2004) Genes Chromosomes Cancer , vol.40 , pp. 152-157
    • Makretsov, N.1    He, M.2    Hayes, M.3
  • 64
    • 23844476815 scopus 로고    scopus 로고
    • Secretory carcinoma of the breast. Case report and review of the literature
    • Ozguroglu M, Tascilar K, Ilvan S, et al. Secretory carcinoma of the breast. Case report and review of the literature. Oncology 2005;68:263-8.
    • (2005) Oncology , vol.68 , pp. 263-268
    • Ozguroglu, M.1    Tascilar, K.2    Ilvan, S.3
  • 65
    • 0031953233 scopus 로고    scopus 로고
    • A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma
    • Knezevich SR, McFadden DE, Tao W, et al. A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. Nat Genet 1998;18:184-7.
    • (1998) Nat Genet , vol.18 , pp. 184-187
    • Knezevich, S.R.1    McFadden, D.E.2    Tao, W.3
  • 66
    • 0031738824 scopus 로고    scopus 로고
    • Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: Cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma
    • Rubin BP, Chen CJ, Morgan TW, et al. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Am J Pathol 1998;153:1451-8.
    • (1998) Am J Pathol , vol.153 , pp. 1451-1458
    • Rubin, B.P.1    Chen, C.J.2    Morgan, T.W.3
  • 67
    • 0033557864 scopus 로고    scopus 로고
    • Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25)
    • Eguchi M, Eguchi-Ishimae M, Tojo A, et al. Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25). Blood 1999;93:1355-63.
    • (1999) Blood , vol.93 , pp. 1355-1363
    • Eguchi, M.1    Eguchi-Ishimae, M.2    Tojo, A.3
  • 68
    • 0028090302 scopus 로고
    • The Trk family of neurotrophin receptors
    • Barbacid M. The Trk family of neurotrophin receptors. J Neurobiol 1994;25:1386-403.
    • (1994) J Neurobiol , vol.25 , pp. 1386-1403
    • Barbacid, M.1
  • 69
    • 59149096465 scopus 로고    scopus 로고
    • Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum
    • Laé M, Fréneaux P, Sastre-Garau X, et al. Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum. Mod Pathol 2009;22:291-8.
    • (2009) Mod Pathol , vol.22 , pp. 291-298
    • Laé, M.1    Fréneaux, P.2    Sastre-Garau, X.3
  • 70
    • 0038122822 scopus 로고    scopus 로고
    • A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene
    • Adelaide J, Huang HE, Murati A, et al. A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene. Genes Chromosomes Cancer 2003;37:333-45.
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 333-345
    • Adelaide, J.1    Huang, H.E.2    Murati, A.3
  • 71
    • 4444280219 scopus 로고    scopus 로고
    • Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases
    • Hahn Y, Bera TK, Gehlhaus K, et al. Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases. Proc Natl Acad Sci U S A 2004;101:13257-61.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13257-13261
    • Hahn, Y.1    Bera, T.K.2    Gehlhaus, K.3
  • 72
    • 0036883717 scopus 로고    scopus 로고
    • Cloning of BCAS3 (17q23) and BCAS4 (20q13) genes that undergo amplification, overexpression, and fusion in breast cancer
    • Barlund M, Monni O, Weaver JD, et al. Cloning of BCAS3 (17q23) and BCAS4 (20q13) genes that undergo amplification, overexpression, and fusion in breast cancer. Genes Chromosomes Cancer 2002;35:311-7.
    • (2002) Genes Chromosomes Cancer , vol.35 , pp. 311-317
    • Barlund, M.1    Monni, O.2    Weaver, J.D.3
  • 73
    • 33750378672 scopus 로고    scopus 로고
    • Evidence of recurrent gene fusions in common epithelial tumors
    • Kumar-Sinha C, Tomlins SA, Chinnaiyan AM. Evidence of recurrent gene fusions in common epithelial tumors. Trends Mol Med 2006;12:529-36.
    • (2006) Trends Mol Med , vol.12 , pp. 529-536
    • Kumar-Sinha, C.1    Tomlins, S.A.2    Chinnaiyan, A.M.3
  • 74
    • 39049170313 scopus 로고    scopus 로고
    • Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer
    • Helgeson BE, Tomlins SA, Shah N, et al. Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer. Cancer Res 2008;68:73-80.
    • (2008) Cancer Res , vol.68 , pp. 73-80
    • Helgeson, B.E.1    Tomlins, S.A.2    Shah, N.3
  • 75
    • 34547642493 scopus 로고    scopus 로고
    • Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
    • Tomlins SA, Laxman B, Dhanasekaran SM, et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 2007;448:595-9.
    • (2007) Nature , vol.448 , pp. 595-599
    • Tomlins, S.A.1    Laxman, B.2    Dhanasekaran, S.M.3
  • 76
    • 44849123245 scopus 로고    scopus 로고
    • Two unique novel prostatespecific and androgen-regulated fusion partners of ETV4 in prostate cancer
    • Hermans KG, Bressers AA, van der Korput HA, et al. Two unique novel prostatespecific and androgen-regulated fusion partners of ETV4 in prostate cancer. Cancer Res 2008;68:3094-8.
    • (2008) Cancer Res , vol.68 , pp. 3094-3098
    • Hermans, K.G.1    Bressers, A.A.2    van der Korput, H.A.3
  • 77
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007;448:561-6.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 78
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008;3:13-7.
    • (2008) J Thorac Oncol , vol.3 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 79
    • 57349113565 scopus 로고    scopus 로고
    • Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts
    • Takeuchi K, Choi YL, Soda M, et al. Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res 2008;14:6618-24.
    • (2008) Clin Cancer Res , vol.14 , pp. 6618-6624
    • Takeuchi, K.1    Choi, Y.L.2    Soda, M.3
  • 80
    • 65249095599 scopus 로고    scopus 로고
    • The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
    • Wong DW, Leung EL, So KK, et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009;115:1723-33.
    • (2009) Cancer , vol.115 , pp. 1723-1733
    • Wong, D.W.1    Leung, E.L.2    So, K.K.3
  • 81
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008;14:4275-83.
    • (2008) Clin Cancer Res , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullahu, K.3
  • 82
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007;131:1190-203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3
  • 83
    • 63949086127 scopus 로고    scopus 로고
    • KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
    • Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 2009;15:3143-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 3143-3149
    • Takeuchi, K.1    Choi, Y.L.2    Togashi, Y.3
  • 84
    • 47649105190 scopus 로고    scopus 로고
    • EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas
    • Shinmura K, Kageyama S, Tao H, et al. EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung Cancer 2008;61:163-9.
    • (2008) Lung Cancer , vol.61 , pp. 163-169
    • Shinmura, K.1    Kageyama, S.2    Tao, H.3
  • 85
    • 67650441507 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
    • Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol 2009;40:1152-8.
    • (2009) Hum Pathol , vol.40 , pp. 1152-1158
    • Boland, J.M.1    Erdogan, S.2    Vasmatzis, G.3
  • 86
    • 58149382583 scopus 로고    scopus 로고
    • A mouse model for EML4-ALK-positive lung cancer
    • Soda M, Takada S, Takeuchi K, et al. A mouse model for EML4-ALK-positive lung cancer. Proc Natl Acad Sci U S A 2008;105:19893-7.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19893-19897
    • Soda, M.1    Takada, S.2    Takeuchi, K.3
  • 87
    • 73249115584 scopus 로고    scopus 로고
    • Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
    • Persson M, Andrén Y, Mark J, et al. Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc Natl Acad Sci USA 2009;106:18740-4.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18740-18744
    • Persson, M.1    Andrén, Y.2    Mark, J.3


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