Conserved mechanism of PLAG1 activation in salivary gland tumors with and without chromosome 8q12 abnormalities: Identification of SII as a new fusion partner gene

Cancer Research

Volumn 59, Issue 4, 1999, Pages 918-923

  Åström, Anna Karin ^a   Voz, Marianne L ^b   Kas, Koen ^b   Röijer, Eva ^a   Wedell, Barbro ^a   Mandahl, Nils ^c   Van De Ven, Wim ^b   Mark, Joachim ^a,d   Stenman, Göran ^a,e  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d CENTRAL HOSPITAL   (Sweden)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 8Q; CHROMOSOME ABERRATION; FUSION GENE; GENE ACTIVATION; GENE FUSION; GENE OVEREXPRESSION; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; KARYOTYPE; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PLEOMORPHIC ADENOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVARY GLAND TUMOR; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ARTIFICIAL GENE FUSION; BASE SEQUENCE; BLOTTING, NORTHERN; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 8; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASES; SALIVARY GLAND NEOPLASMS; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, GENERAL; TRANSCRIPTIONAL ELONGATION FACTORS;

EID: 2542508022     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Kas, K., Voz, M. L., Röijer, E., Åström, A-K., Meyen, E., Stenman, G., and Van de Ven, W. J. Promoter swapping between the genes for a novel zinc finger protein and β-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations. Nat. Genet., 15: 170-174, 1997.
2. Kas, K., Röijer, E., Voz, M., Meyen, E., Stenman, G., and Van de Ven, W. J. A 2-Mb YAC contig and physical map covering the chromosome 8q12 breakpoint cluster region in pleomorphic adenomas of the salivary glands. Genomics, 43: 349-358, 1997.
3. Kas, K., Voz, M. L., Hensen, K., Meyen, E., and Van de Ven, W. J. M. Transcriptional activation capacity of the novel PLAG family of zinc finger proteins. J. Biol. Chem., 273: 23026-23032, 1998.
4. Peifer, M. β-catenin as oncogene: the smoking gun. Science (Washington DC), 275: 1752-1753, 1997.
5. Willert, K., and Nusse, R. β-catenin: a key mediator of Wnt signaling. Curr. Opin. Genet. Dev., 8: 95-102, 1998.
6. Voz, M. L., Åström, A-K., Kas, K. Mark, J., Stenman, G., and Van de Ven, W. J. The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter. Oncogene, 16: 1409-1416, 1998.
7. Gearing, D. P., Thut, C. J., VandeBos, T., Gimpel, S. D., Delaney, P. B., King, J., Price, V., Cosman, D., and Beckmann, M. P. Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J., 10: 2839-2848, 1991.
8. Sandros, J., Stenman, G., and Mark, J. Cytogenetic and molecular observations in human and experimental salivary gland tumors. Cancer Genet. Cytogenet., 44: 153-167, 1990.
9. Bullerdiek, J., Wobst, G., Meyer-Bolte, K., Chilla, R., Haubrich, J., Thode, B., and Bartnitzke, S. Cytogenetic subtyping of 220 salivary gland pleomorphic adenomas: correlation to occurrence, histological subtype, and in vitro cellular behavior. Cancer Genet. Cytogenet., 65: 27-31, 1993.
10. Mark, J., Dahlenfors, R., and Wedell, B. Impact of the in vitro technique used on the cytogenetic patterns in pleomorphic adenomas. Cancer Genet. Cytogenet., 95: 9-15, 1997.
11. Schoenmakers, E. F., Wanschura, S., Mols, R., Bullerdiek, J., Van den Berghe, H., and Van de Ven, W. J. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat. Genet., 10: 436-444, 1995.
12. Geurts, J. M., Schoenmakers, E. F., Röijer, E., Stenman, G., and Van de Ven, W. J. Expression of reciprocal hybrid transcripts of HMGIC and FHIT in a pleomorphic adenoma of the parotid gland. Cancer Res, 57: 13-17, 1997.
13. Geurts, J. M., Schoenmakers, E. F., Röijer, E., Åström, A-K., Stenman, G., and van de Ven, W. J. Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas. Oncogene, 16: 865-872, 1998.
14. Ashar, H. R., Fejzo, M. S., Tkachenko, A., Zhou, X., Fletcher, J. A., Weremowicz, S., Morton, C. C., and Chada, K. Disruption of the architectural factor HMGI-C. DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell. 82: 57-65, 1995.
15. Petit, M. M. R., Mols, R., Schoenmakers, E. F., Mandahl, N., and Van de Ven, W. J. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics, 36: 118-129, 1996.
16. Rogalla, P., Kazmierczak, B., Meyer-Bolle, K., Tran, K. H., and Bullerdick, J. The t(3;12)(q27;q14-q15) with underlying HMGIC-LPP fusion is not determining an adipocytic phenotype. Genes Chromosomes Cancer, 22; 100-104, 1998.
17. Nordkvist, A., Mark, J., Gustafsson, H., Bang, G., and Stenman, G. Non-random chromosome rearrangements in adenoid cystic carcinoma of the salivary glands. Genes Chromosomes Cancer, 10: 115-121, 1994.
18. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd ed., pp. 1.1-18.88. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
19. Baier, G., Telford, D., Gulbins, E., Yamada, N., Kawakami, T., and Allman, A. Improved specificity of RT-PCR amplifications using nested cDNA primers. Nucleic-Acids Res., 21: 1329-1330, 1993.
20. DiMarco, S. P., Glover, T. W., Miller, D. E., Reines, D., and Warren, S. T. Transcription elongation factor SII (TCEA) maps to human chromosome 3p22->p21.3. Genomics, 36: 185-188, 1996.
21. Park, H., Back, K., Jeon, C., Agarwal, K., and Yoo, O. Characterization of the gene-encoding the human transcriptional elongation factor TFIIS. Gene, 139: 263-267, 1994.
22. Reines, D., Conaway, J. W., and Conaway, R. C. The RNA polymerase II general elongation factors. Trends Biochem. Sci., 21: 351-355, 1996.
23. Kanai, A., Kuzuhara, T., Sekimizu, K., and Natori, S. Heterogeneity and tissue-specific expression of eukaryotic transcription factor S-II-related protein mRNA. J. Biochem. (Tokyo). 109: 674-677, 1991.
24. Plant, K. E., Hair, A., and Morgan, G. T. Genes encoding isoforms of transcription elongation factor TFIIS in Xenopus and the use of multiple unusual RNA processing signals. Nucleic Acids Res., 24: 3514-3521, 1996.
25. Weaver, Z. A., and Kane, C. M. Genomic characterization of a testis-specific TFIIS (TCEA2) gene. Genomics. 46: 516-519, 1997.
26. Akasaka, T., Miura, I., Takahashi, N., Akasaka, H., Yonetani, N., Ohno, H., Fukuhara, S., and Okuma, M. A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5′ regulatory region of BCL6 with a novel H4 histone gene. Cancer Res., 57: 7-12, 1997.
27. Migliazza, A., Martinotti, S., Chen, W., Fusco, C., Ye, B. H., Knowles, D. M., Offit, K., Chaganti, R. S., and Dalla-Favera, R. Frequent somatic hypermutation of the 5′ noncoding region of the BCL6 gene in B-cell lymphoma. Proc. Natl. Acad. Sci. USA, 92: 12520-12524, 1995.
28. Bernardin, F., Collyn-d'Hooghe, M., Quief, S., Bastard, C., Leprince, D., and Kerckaert, J. P. Small deletions occur in highly conserved regions of the LAZ3/BCL6 major translocation cluster in one case of non-Hodgkin's lymphoma without 3q27 translocation. Oncogene, 14: 849-855, 1997.
29. Nakamura, Y., Miki, T., Kawamata, N., Hirosawa, S., Saito, K., Enokihara, H., Furosawa, S., and Shishido, H. Biallelic DNA rearrangements and deletions within the BCL-6 gene in B-cell non-Hodgkin's lymphoma. Br J. Haematol., 90: 404-408, 1995.
30. Gnepp, D. R., and Wenig, B. M. Malignant mixed tumors. In: G. L. Ellis, P. L. Auclair, and D. R. Gnepp (eds.), Surgical Pathology of the Salivary Glands, Vol. 25, pp. 350-368, Philadelphia: W. B. Saunders Company, 1991.