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Volumn 1161, Issue 1-2, 2007, Pages 29-35

Fast determination of conditions for maximum dynamic capacity in cation-exchange chromatography of human monoclonal antibodies

(4) Faude, Alexander a Zacher, Dörthe a Müller, Egbert b Böttinger, Heiner a

a UNIVERSITY OF STUTTGART (Germany)

b TOSOH CORPORATION (Japan)

Author keywords

Cation exchange chromatography; Dynamic binding capacity; Hofmeister series; Human monoclonal antibodies; Purification process development; Zeta potential

Indexed keywords

CATION-EXCHANGE CHROMATOGRAPHY; HOFMEISTER SERIES; HUMAN MONOCLONAL ANTIBODIES; PURIFICATION PROCESS DEVELOPMENT;

BINDING ENERGY; CHROMATOGRAPHIC ANALYSIS; ION EXCHANGE; PH EFFECTS; PURIFICATION; ZETA POTENTIAL;

ANTIBODIES;

ACETIC ACID; BUFFER; MONOCLONAL ANTIBODY; POTASSIUM ION; SODIUM DIHYDROGEN PHOSPHATE; SODIUM ION;

ADSORPTION; ARTICLE; BINDING AFFINITY; CONDUCTANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; HOFMEISTER SERIES; ION EXCHANGE CHROMATOGRAPHY; IONIC STRENGTH; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROTEIN PURIFICATION; SALTING OUT; SOLUBILITY; SURFACE TENSION; TITRIMETRY; ZETA POTENTIAL;

ANTIBODIES, MONOCLONAL; CATION EXCHANGE RESINS; CHROMATOGRAPHY, ION EXCHANGE; HUMANS; HYDROGEN-ION CONCENTRATION;

EID: 34447638512 PISSN: 00219673 EISSN: None Source Type: Journal
DOI: 10.1016/j.chroma.2007.03.114 Document Type: Article

Times cited : (28)

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