BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK

Cellular Signalling

Volumn 19, Issue 7, 2007, Pages 1465-1472

  Beck, Stayce E ^a,b   Jung, Barbara H ^a,b,c   Del Rosario, Eunice ^a   Gomez, Jessica ^a,b   Carethers, John M ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Bone morphogenetic protein; Colorectal cancer; ERK; RAS; TGF

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHO SMAD1 PROTEIN; SMAD1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER CONTROL; CANCER GROWTH; COLORECTAL CANCER; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOGENESIS; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

BONE MORPHOGENETIC PROTEINS; CELL NUCLEUS; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; PROTEIN KINASE INHIBITORS; PTEN PHOSPHOHYDROLASE; RAS PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; THERMODYNAMICS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 34249340845     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.01.017     Document Type: Article

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