Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 47, 2009, Pages 19807-19812

  De Marco, V ^a,f   Gillespie, P J ^b   Li, A ^b   Karantzelis, N ^c   Christodoulou, E ^a,f   Klompmaker, R ^d   Van Gerwen, S ^a   Fish, A ^a   Petoukhov, M V ^e   Iliou, M S ^c,g   Lygerou, Z ^c   Medema, R H ^d   Blow, J J ^b   Svergun, D I ^e   Taraviras, S ^c   Perrakis, A ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF PATRAS   (Greece)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^f NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^g CATALAN INSTITUTE OF ONCOLOGY   (Spain)

Author keywords

Cell cycle; Pre RC; Solution structure; X ray structure

Indexed keywords

GEMININ; PROTEIN; REPLICATION LICENSING FACTOR CDT1; REPLICATION LICENSING FACTOR CDT1 GEMININ COMPLEX; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CHROMATIN; DNA REPLICATION; HUMAN; HUMAN CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DNA REPLICATION; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SCATTERING, SMALL ANGLE; SEQUENCE ALIGNMENT; X-RAY DIFFRACTION; XENOPUS LAEVIS;

EUKARYOTA; MAMMALIA;

EID: 73649143080     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905281106     Document Type: Article

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