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Volumn 10, Issue 1, 2005, Pages 63-73

Intrinsic nuclear import acitivity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; GEMININ; PROTEASOME INHIBITOR; RECOMBINANT PROTEIN; REGULATOR PROTEIN; REPLICATION LICENSING FACTOR CDT1; UNCLASSIFIED DRUG;

EID: 14844357222     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2005.00815.x     Document Type: Article
Times cited : (52)

References (37)
  • 1
    • 8544283842 scopus 로고    scopus 로고
    • Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity
    • Benjamin, J.M., Torke, S.J., Demeler, B. & McGarry, T.J. (2004) Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity. J. Biol. Chem. 279, 45957-45968.
    • (2004) J. Biol. Chem. , vol.279 , pp. 45957-45968
    • Benjamin, J.M.1    Torke, S.J.2    Demeler, B.3    McGarry, T.J.4
  • 2
    • 0023904730 scopus 로고
    • A role for the nuclear envelope in controlling DNA replication within the cell cycle
    • Blow, J.J. & Laskey, R.A. (1988) A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature 332 546-548.
    • (1988) Nature , vol.332 , pp. 546-548
    • Blow, J.J.1    Laskey, R.A.2
  • 3
    • 0036470433 scopus 로고    scopus 로고
    • Replication licensing - Defining the proliferative state?
    • Blow, J.J. & Hodgson, B. (2002) Replication licensing - defining the proliferative state? Trends Cell Biol. 12, 72-78.
    • (2002) Trends Cell Biol. , vol.12 , pp. 72-78
    • Blow, J.J.1    Hodgson, B.2
  • 4
    • 0027177595 scopus 로고
    • Reversible effects of nuclear membrane permeabilization on DNA replication: Evidence for a positive licensing factor
    • Coverley, D., Downes, C.S., Romanowski, P. & Laskey, R.A. (1993) Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor. J. Cell Biol. 122, 985-992.
    • (1993) J. Cell Biol. , vol.122 , pp. 985-992
    • Coverley, D.1    Downes, C.S.2    Romanowski, P.3    Laskey, R.A.4
  • 5
    • 0029410629 scopus 로고
    • S-phasepromoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state
    • Dahmann, C., Diffley, J.F. & Nasmyth, K.A. (1995) S-phasepromoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state. Curr. Biol. 5, 1257-1269.
    • (1995) Curr. Biol. , vol.5 , pp. 1257-1269
    • Dahmann, C.1    Diffley, J.F.2    Nasmyth, K.A.3
  • 6
    • 0001128975 scopus 로고    scopus 로고
    • Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis
    • Findeisen, M., El-Denary, M., Kapitza, T., Graf, R. & Strausfeld, U. (1999) Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis. Eur. J. Biochem. 264, 415-426.
    • (1999) Eur. J. Biochem. , vol.264 , pp. 415-426
    • Findeisen, M.1    El-Denary, M.2    Kapitza, T.3    Graf, R.4    Strausfeld, U.5
  • 7
    • 0033520321 scopus 로고    scopus 로고
    • Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation
    • Fujita, M., Yamada, C., Goto, H., et al. (1999) Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation. J. Biol. Chem. 274, 25927-25932.
    • (1999) J. Biol. Chem. , vol.274 , pp. 25927-25932
    • Fujita, M.1    Yamada, C.2    Goto, H.3
  • 9
    • 0037900888 scopus 로고    scopus 로고
    • Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication
    • Hashimoto, Y. & Takisawa, H. (2003) Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication. EMBO J. 22, 2526-2535.
    • (2003) EMBO J. , vol.22 , pp. 2526-2535
    • Hashimoto, Y.1    Takisawa, H.2
  • 10
    • 0028059299 scopus 로고
    • Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
    • Hayles, J., Fisher, D., Woollard, A. & Nurse, P. (1994) Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex. Cell 78, 813 -822.
    • (1994) Cell , vol.78 , pp. 813-822
    • Hayles, J.1    Fisher, D.2    Woollard, A.3    Nurse, P.4
  • 11
    • 0029861615 scopus 로고    scopus 로고
    • Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex
    • Hendrickson, M., Madine, M., Dalton, S. & Gautier, J. (1996) Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex. Proc. Natl. Acad. Sci. USA 93, 12223-12228.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12223-12228
    • Hendrickson, M.1    Madine, M.2    Dalton, S.3    Gautier, J.4
  • 12
    • 0037117415 scopus 로고    scopus 로고
    • Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import
    • Hodgson, B., Li, A., Tada, S. & Blow, J.J. (2002) Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import. Curr. Biol. 12, 678-683.
    • (2002) Curr. Biol. , vol.12 , pp. 678-683
    • Hodgson, B.1    Li, A.2    Tada, S.3    Blow, J.J.4
  • 13
    • 0029000522 scopus 로고
    • Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor
    • Kubota, Y., Mimura, S., Nishimoto, S., Takisawa, H. & Nojima, H. (1995) Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor. Cell 81, 601-609.
    • (1995) Cell , vol.81 , pp. 601-609
    • Kubota, Y.1    Mimura, S.2    Nishimoto, S.3    Takisawa, H.4    Nojima, H.5
  • 14
    • 0027716212 scopus 로고
    • Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts
    • Kubota, Y. & Takisawa, H. (1993) Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts. J. Cell Biol. 123, 1321-1331.
    • (1993) J. Cell Biol. , vol.123 , pp. 1321-1331
    • Kubota, Y.1    Takisawa, H.2
  • 15
    • 0031007453 scopus 로고    scopus 로고
    • Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs
    • Kubota, Y., Mimura, S., Nishimoto, S., Masuda, T., Nojima, H. & Takisawa, H. (1997) Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs. EMBO J. 16, 3320-3331.
    • (1997) EMBO J. , vol.16 , pp. 3320-3331
    • Kubota, Y.1    Mimura, S.2    Nishimoto, S.3    Masuda, T.4    Nojima, H.5    Takisawa, H.6
  • 16
    • 0037126313 scopus 로고    scopus 로고
    • Competence to replicate in the unfertilized egg is conferred by Cdc6 during meiotic maturation
    • Lemaitre, J.M., Bocquet, S. & Mechali, M. (2002) Competence to replicate in the unfertilized egg is conferred by Cdc6 during meiotic maturation. Nature 419, 718-722.
    • (2002) Nature , vol.419 , pp. 718-722
    • Lemaitre, J.M.1    Bocquet, S.2    Mechali, M.3
  • 17
    • 2342442851 scopus 로고    scopus 로고
    • Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation
    • Liu, E., Li, X., Yan, F., Zhao, Q. & Wu, X. (2004) Cyclindependent kinases phosphorylate human Cdt1 and induce its degradation. J. Biol. Chem. 279, 17283-17288.
    • (2004) J. Biol. Chem. , vol.279 , pp. 17283-17288
    • Liu, E.1    Li, X.2    Yan, F.3    Zhao, Q.4    Wu, X.5
  • 18
    • 0032714974 scopus 로고    scopus 로고
    • DNA replication in quiescent cell nuclei: Regulation by the nuclear envelope and chromatin structure
    • Lu, Z.H., Xu, H. & Leno, G.H. (1999) DNA replication in quiescent cell nuclei: regulation by the nuclear envelope and chromatin structure. Mol. Biol. Cell 10, 4091-4106.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 4091-4106
    • Lu, Z.H.1    Xu, H.2    Leno, G.H.3
  • 19
    • 0032511148 scopus 로고    scopus 로고
    • Geminin, an inhibitor of DNA replication, is degraded during mitosis
    • McGarry, T.J. & Kirschner, M.W. (1998) Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell 93, 1043-1053.
    • (1998) Cell , vol.93 , pp. 1043-1053
    • McGarry, T.J.1    Kirschner, M.W.2
  • 20
    • 2542429354 scopus 로고    scopus 로고
    • Loss of Geminin induces rereplication in the presence of functional p53
    • Melixetian, M., Ballabeni, A., Masiero, L., et al. (2004) Loss of Geminin induces rereplication in the presence of functional p53. J. Cell Biol. 165, 473-482.
    • (2004) J. Cell Biol. , vol.165 , pp. 473-482
    • Melixetian, M.1    Ballabeni, A.2    Masiero, L.3
  • 21
    • 0036182133 scopus 로고    scopus 로고
    • Control of DNA replication and chromosome ploidy by geminin and cyclin A
    • Mihaylov, I.S., Kondo, T., Jones, L., et al. (2002) Control of DNA replication and chromosome ploidy by geminin and cyclin A. Mol. Cell. Biol. 22, 1868-1880.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1868-1880
    • Mihaylov, I.S.1    Kondo, T.2    Jones, L.3
  • 22
    • 0032190507 scopus 로고    scopus 로고
    • Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk
    • Mimura, S. & Takisawa, H. (1998) Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. EMBO J. 17, 5699-5707.
    • (1998) EMBO J. , vol.17 , pp. 5699-5707
    • Mimura, S.1    Takisawa, H.2
  • 23
    • 5344241161 scopus 로고    scopus 로고
    • A Role for Ran-GTP and Crml in Blocking Re-Replication
    • Newport. J. (2004) A Role for Ran-GTP and Crml in Blocking Re-Replication. Cell 119, 145.
    • (2004) Cell , vol.119 , pp. 145
    • Newport, J.1
  • 24
    • 0035963372 scopus 로고    scopus 로고
    • Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
    • Nguyen, V.Q., Co, C. & Li, J.J. (2001) Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. Nature 411, 1068-1073.
    • (2001) Nature , vol.411 , pp. 1068-1073
    • Nguyen, V.Q.1    Co, C.2    Li, J.J.3
  • 25
    • 0035998262 scopus 로고    scopus 로고
    • Control of DNA replication licensing in a cell cycle
    • Nishitani, H. & Lygerou, Z. (2002) Control of DNA replication licensing in a cell cycle. Genes Cells 7, 523-534.
    • (2002) Genes Cells , vol.7 , pp. 523-534
    • Nishitani, H.1    Lygerou, Z.2
  • 26
    • 0034611749 scopus 로고    scopus 로고
    • The Cdt1 protein is required to license DNA for replication in fission yeast
    • Nishitani, H., Lygerou, Z., Nishimoto, T. & Nurse, P. (2000) The Cdt1 protein is required to license DNA for replication in fission yeast. Nature 404, 625-628.
    • (2000) Nature , vol.404 , pp. 625-628
    • Nishitani, H.1    Lygerou, Z.2    Nishimoto, T.3    Nurse, P.4
  • 27
    • 0035976980 scopus 로고    scopus 로고
    • The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase
    • Nishitani, H., Taraviras, S., Lygerou, Z. & Nishimoto, T. (2001) The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase. J. Biol. Chem. 276 44905-44911.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44905-44911
    • Nishitani, H.1    Taraviras, S.2    Lygerou, Z.3    Nishimoto, T.4
  • 28
    • 3142766071 scopus 로고    scopus 로고
    • Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region
    • Nishitani, H., Lygerou, Z. & Nishimoto, T. (2004) Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region. J. Biol. Chem. 279 30807-30816.
    • (2004) J. Biol. Chem. , vol.279 , pp. 30807-30816
    • Nishitani, H.1    Lygerou, Z.2    Nishimoto, T.3
  • 29
    • 2442427423 scopus 로고    scopus 로고
    • Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding
    • Sugimoto, N., Tatsumi, Y., Tsurumi, T., et al. (2004) Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. J. Biol. Chem. 279 19691-19697.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19691-19697
    • Sugimoto, N.1    Tatsumi, Y.2    Tsurumi, T.3
  • 30
    • 0002257482 scopus 로고    scopus 로고
    • The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins
    • Sun, W., Hola, M., Pedley, K., et al. (2000) The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. J. Cell Sci. 113, 683-695.
    • (2000) J. Cell Sci. , vol.113 , pp. 683-695
    • Sun, W.1    Hola, M.2    Pedley, K.3
  • 31
    • 0035147434 scopus 로고    scopus 로고
    • Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
    • Tada, S., Li, A., Maiorano, D., Mechali, M. & Blow, J.J. (2001) Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin. Nature Cell Biol. 3, 107-113.
    • (2001) Nature Cell Biol. , vol.3 , pp. 107-113
    • Tada, S.1    Li, A.2    Maiorano, D.3    Mechali, M.4    Blow, J.J.5
  • 32
    • 0037623356 scopus 로고    scopus 로고
    • A p53-dependent checkpoint pathway prevents rereplication
    • Vaziri, C., Saxena, S., Jeon, Y., et al. (2003) A p53-dependent checkpoint pathway prevents rereplication. Mol. Cell 11, 997-1008.
    • (2003) Mol. Cell , vol.11 , pp. 997-1008
    • Vaziri, C.1    Saxena, S.2    Jeon, Y.3
  • 33
    • 0037126302 scopus 로고    scopus 로고
    • Cdc6 synthesis regulates replication competence in Xenopus oocytes
    • Whitmire, E., Khan, B. & Coue, M. (2002) Cdc6 synthesis regulates replication competence in Xenopus oocytes. Nature 419, 722-725.
    • (2002) Nature , vol.419 , pp. 722-725
    • Whitmire, E.1    Khan, B.2    Coue, M.3
  • 35
    • 0035801342 scopus 로고    scopus 로고
    • Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication
    • Yanow, S.K., Lygerou, Z. & Nurse, P. (2001) Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication. EMBO J. 20, 4648-4656.
    • (2001) EMBO J. , vol.20 , pp. 4648-4656
    • Yanow, S.K.1    Lygerou, Z.2    Nurse, P.3
  • 36
    • 0037967230 scopus 로고    scopus 로고
    • CUL4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing
    • Zhong, W., Feng, H., Santiago, F.E. & Kipreos, E.T. (2003) CUL4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing. Nature 423, 885-889.
    • (2003) Nature , vol.423 , pp. 885-889
    • Zhong, W.1    Feng, H.2    Santiago, F.E.3    Kipreos, E.T.4
  • 37
    • 3543041247 scopus 로고    scopus 로고
    • Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint
    • Zhu, W., Chen, Y. & Dutta, A. (2004) Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint. Mol. Cell. Biol. 24, 7140 -7150.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7140-7150
    • Zhu, W.1    Chen, Y.2    Dutta, A.3


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