Effect of arachidonyl-2′-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 34, Issue 1, 2010, Pages 18-25

  Luszczki, Jarogniew J ^a,b   Czuczwar, Piotr ^a   Cioczek Czuczwar, Anna ^a   Dudra Jastrzebska, Monika ^a,b   Andres Mach, Marta ^b   Czuczwar, Stanislaw J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

ACEA; Antiepileptic drugs; Cannabinoids; Maximal electroshock seizure model; Pharmacokinetic pharmacodynamic interaction; Protective index

Indexed keywords

ARACHIDONYL 2' CHLOROETHYLAMIDE; BENZYLSULFONYL FLUORIDE; CANNABINOID 1 RECEPTOR AGONIST; CARBAMAZEPINE; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; TOPIRAMATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG BRAIN LEVEL; DRUG MECHANISM; DRUG POTENTIATION; ELECTRIC SHOCK; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; SEIZURE; TOXICITY TESTING;

ANIMALS; ANTICONVULSANTS; ARACHIDONIC ACIDS; AVOIDANCE LEARNING; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; ELECTROSHOCK; ENZYME INHIBITORS; MALE; MEMORY DISORDERS; MICE; MUSCLE STRENGTH; MUSCLE, SKELETAL; PHENYLMETHYLSULFONYL FLUORIDE; PSYCHOMOTOR PERFORMANCE; RECEPTOR, CANNABINOID, CB1; SEIZURES;

EID: 73649113131     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2009.09.005     Document Type: Article

References (63)

1. Angehagen M., Ben-Menachem E., Shank R., Ronnback L., and Hansson E. Topiramate modulation of kainate-induced calcium currents is inversely related to channel phosphorylation level. J Neurochem 88 (2004) 320-325
2. Bahremand A., Nasrabady S.E., Shafaroodi H., Ghasemi M., and Dehpour A.R. Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice. Epilepsy Res 84 (2009) 110-119
3. Bidaut-Russell M., and Howlett A.C. Cannabinoid receptor-regulated cyclic AMP accumulation in the rat striatum. J Neurochem 57 (1991) 1769-1773
4. Bidaut-Russell M., Devane W.A., and Howlett A.C. Cannabinoid receptors and modulation of cyclic AMP accumulation in the rat brain. J Neurochem 55 (1990) 21-26
5. Blair R.E., Deshpande L.S., Sombati S., Falenski K.W., Martin B.R., and DeLorenzo R.J. Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquire epilepsy and status epilepticus. J Pharmacol Exp Ther 317 (2006) 1072-1078
6. Boissier J.R., Tardy J., and Diverres J.C. Une nouvelle méthode simple pour explorer l'action tranquilisante: le test de la cheminée. Med Exp (Basel) 3 (1960) 81-84
7. Borowicz K.K., Kleinrok Z., and Czuczwar S.J. Influence of 7-nitroindazole on the anticonvulsive action of conventional antiepileptic drugs. Eur J Pharmacol 331 (1997) 127-132
8. Borowicz K.K., Starownik R., Kleinrok Z., and Czuczwar S.J. The influence of L-NG-nitroarginine methyl ester, an inhibitor of nitric oxide synthase, upon the anticonvulsive activity of conventional antiepileptic drugs against maximal electroshock in mice. J Neural Transm 105 (1998) 1-12
9. Brodie M.J., and Schachter S.C. Fast facts. Epilepsy. 2nd ed. (2001), Health Press, Oxford
10. Compton D.R., and Martin B.R. The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. J Pharmacol Exp Ther 283 (1997) 1138-1143
11. Consroe P.F., Wood G.C., and Buchsbaum H. Anticonvulsant nature of marihuana smoking. JAMA 234 (1975) 306-307
12. Cunha J.M., Carlini E.A., Pereira A.E., Ramos O.L., Pimentel C., Gagliardi R., et al. Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Pharmacology 21 (1980) 175-185
13. Deadwyler S.A., Hampson R.E., Bennett B.A., Edwards T.A., Mu J., Pacheco M.A., et al. Cannabinoids modulate potassium current in cultured hippocampal neurons. Recept Channels 1 (1993) 121-134
14. Dodgson S.J., Shank R.P., and Maryanoff B.E. Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia 41 Suppl 1 (2000) S35-S39
15. Ellison J.M., Gelwan E., and Ogletree J. Complex partial seizure symptoms affected by marijuana abuse. J Clin Psychiatry 51 (1990) 439-440
16. Falenski K.W., Carter D.S., Harrison A.J., Martin B.R., Blair R.E., and DeLorenzo R.J. Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus. Brain Res 1262 (2009) 64-72
17. Gholizadeh S., Shafaroodi H., Ghasemi M., Bahremand A., Sharifzadeh M., and Dehpour A.R. Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice. Neuropharmacology 53 (2007) 763-770
18. Giang D.K., and Cravatt B.F. Molecular characterization of human and mouse fatty acid amide hydrolases. Proc Natl Acad Sci USA 94 (1997) 2238-2242
19. Gibbs J.W., Sombati S., DeLorenzo R.J., and Coulter D.A. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 41 Suppl 1 (2000) S10-S16
20. Gordon E., and Devinsky O. Alcohol and marijuana: effects on epilepsy and use by patients with epilepsy. Epilepsia 42 (2001) 1266-1272
21. Gryder D.S., and Rogawski M.A. Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons. J Neurosci 23 (2003) 7069-7074
22. Hampson R.E., Evans G.J., Mu J., Zhuang S.Y., King V.C., Childers S.R., et al. Role of cyclic AMP dependent protein kinase in cannabinoid receptor modulation of potassium "A-current" in cultured rat hippocampal neurons. Life Sci 56 (1995) 2081-2088
23. Herrero A.I., Del Olmo N., Gonzalez-Escalada J.R., and Solis J.M. Two new actions of topiramate: inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance. Neuropharmacology 42 (2002) 210-220
24. Ko G.Y., Brown-Croyts L.M., and Teyler T.J. The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus. Brain Res Bull 42 (1997) 297-302
25. Koda S., Takeda S., Onimaru H., Akada S., and Sakamoto A. Cannabinoid suppressed bicuculline-induced convulsion without respiratory depression in the brainstem-spinal cord preparation from newborn rats. Biomed Res 26 (2005) 241-247
26. Kwan P., and Brodie M.J. Early identification of refractory epilepsy. N Engl J Med 342 (2000) 314-319
27. Kwan P., and Brodie M.J. Epilepsy after the first drug fails: substitution or add-on?. Seizure 9 (2000) 464-468
28. Litchfield J.T., and Wilcoxon F. A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96 (1949) 99-113
29. Löscher W. Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy. CNS Drugs 16 (2002) 669-694
30. Löscher W., and Fiedler M. The role of technical, biological, and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. VII. Seasonal influences on anticonvulsant drug actions in mouse models of generalized seizures. Epilepsy Res 38 (2000) 231-248
31. Löscher W., and Nolting B. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. IV. Protective indices. Epilepsy Res 9 (1991) 1-10
32. Löscher W., Fassbender C.P., and Nolting B. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models. Epilepsy Res 8 (1991) 79-94
33. Luszczki J.J. Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions. Pharmacol Rep 61 (2009) 197-216
34. Luszczki J.J., Swiader M., Parada-Turska J., and Czuczwar S.J. Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice. Neuropsychopharmacology 28 (2003) 1817-1830
35. Luszczki J.J., Wojcik-Cwikla J., Andres M.M., and Czuczwar S.J. Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis. Neuropsychopharmacology 30 (2005) 958-973
36. Luszczki J.J., Czuczwar M., Gawlik P., Sawiniec-Pozniak G., Czuczwar K., and Czuczwar S.J. 7-Nitroindazole potentiates the anticonvulsant action of some second-generation antiepileptic drugs in the mouse maximal electroshock-induced seizure model. J Neural Transm 113 (2006) 1157-1168
37. Luszczki J.J., Czuczwar M., Gawlik P., Sawiniec-Późniak G., Czuczwar K., Sawicka K.M., et al. Influence of NG-nitro-L-arginine on the anticonvulsant and acute adverse effects of some newer antiepileptic drugs in the maximal electroshock-induced seizures and chimney test in mice. Pharmacol Rep 58 (2006) 955-960
38. Luszczki J.J., Czuczwar P., Cioczek-Czuczwar A., and Czuczwar S.J. Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model. Eur J Pharmacol 547 (2006) 65-74
39. Luszczki J.J., Ratnaraj N., Patsalos P.N., and Czuczwar S.J. Isobolographic analysis of interactions between loreclezole and conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model. Naunyn-Schmiedeberg's Arch Pharmacol 373 (2006) 169-181
40. Luszczki J.J., Sacharuk A., Wojciechowska A., Andres-Mach M.M., Dudra-Jastrzebska M., Mohamed M., et al. 7-Nitroindazole enhances dose-dependently the anticonvulsant activities of conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model. Pharmacol Rep 58 (2006) 660-671
41. Luszczki J.J., Czernecki R., Wojtal K., Borowicz K.K., and Czuczwar S.J. Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model. J Neural Transm 115 (2008) 1485-1493
42. Luszczki J.J., Antkiewicz-Michaluk L., and Czuczwar S.J. Isobolographic analysis of interactions between 1-methyl-1, 2, 3, 4-tetrahydroisoquinoline and four conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model. Eur J Pharmacol 602 (2009) 298-305
43. Luszczki J.J., Sawicka K.M., Kozinska J., Dudra-Jastrzebska M., and Czuczwar S.J. Amiloride enhances the anticonvulsant action of various antiepileptic drugs in the mouse maximal electroshock seizure model. J Neural Transm 116 (2009) 57-66
44. Luszczki J.J., Wojda E., Andres-Mach M., Cisowski W., Glensk M., Glowniak K., et al. Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study. Epilepsy Res 85 (2009) 293-299
45. Mackie K., and Hille B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA 89 (1992) 3825-3829
46. Mackie K., Devane W.A., and Hille B. Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. Mol Pharmacol 44 (1993) 498-503
47. Mackie K., Lai Y., Westenbroek R., and Mitchell R. Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J Neurosci 15 (1995) 6552-6561
48. Maneuf Y.P., Nash J.E., Crossman A.R., and Brotchie J.M. Activation of the cannabinoid receptor by delta 9-tetrahydrocannabinol reduces gamma-aminobutyric acid uptake in the globus pallidus. Eur J Pharmacol 308 (1996) 161-164
49. Marsicano G., Goodenough S., Monory K., Hermann H., Eder M., Cannich A., et al. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302 (2003) 84-88
50. Mathers D.A., Wan X., and Puil E. Barbiturate activation and modulation of GABA(A) receptors in neocortex. Neuropharmacology 52 (2007) 1160-1168
51. Meyer O.A., Tilson H.A., Byrd W.C., and Riley M.T. A method for the routine assessment of fore- and hindlimb grip strength of rats and mice. Neurobehav Toxicol 1 (1979) 233-236
52. Naderi N., Aziz Ahari F., Shafaghi B., Najarkolaei A.H., and Motamedi F. Evaluation of interactions between cannabinoid compounds and diazepam in electroshock-induced seizure model in mice. J Neural Transm 115 (2008) 1501-1511
53. Richardson J.D., Aanonsen L., and Hargreaves K.M. Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia. J Neurosci 18 (1998) 451-457
54. Shafaroodi H., Samini M., Moezi L., Homayoun H., Sadeghipour H., Tavakoli S., et al. The interaction of cannabinoids and opioids on pentylenetetrazole-induced seizure threshold in mice. Neuropharmacology 47 (2004) 390-400
55. Shank R.P., Gardocki I.F., Streeter A.J., and Maryanoff B.E. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanisms of action. Epilepsia 41 Suppl 1 (2000) S3-S9
56. Sieradzan K.A., Fox S.H., Hill M., Dick J.P., Crossman A.R., and Brotchie J.M. Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study. Neurology 57 (2001) 2108-2111
57. + current fractions by the new anticonvulsant topiramate. J Pharmacol Exp Ther 288 (1999) 960-968
58. Venault P., Chapouthier G., de Carvalho L.P., Simiand J., Morre M., Dodd R.H., et al. Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks. Nature 321 (1986) 864-866
59. Wallace M.J., Wiley J.L., Martin B.R., and DeLorenzo R.J. Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. Eur J Pharmacol 428 (2001) 51-57
60. Wallace M.J., Martin B.R., and DeLorenzo R.J. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. Eur J Pharmacol 452 (2002) 295-301
61. Wallace M.J., Blair R.E., Falenski K.W., Martin B.R., and DeLorenzo R.J. The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. J Pharmacol Exp Ther 307 (2003) 129-137
62. White H.S., Brown S.D., Woodhead J.H., Skeen G.A., and Wolf H.H. Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism. Epilepsia 41 Suppl 1 (2000) S17-S20
63. Zhang X., Velumian A.A., Jones O.T., and Carlen P.L. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate. Epilepsia 41 Suppl 1 (2000) S52-S60