7-Nitroindazole potentiates the anticonvulsant action of some second-generation antiepileptic drugs in the mouse maximal electroshock-induced seizure model

Journal of Neural Transmission

Volumn 113, Issue 9, 2006, Pages 1157-1168

  Luszczki, J J ^a   Czuczwar, M ^a   Gawlik, P ^a   Sawiniec Pozniak, G ^a   Czuczwar, K ^a   Czuczwar, S J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

7 Nitroindazole; Chimney test; Felbamate; Lamotrigine; Maximal electroshock; Nitric oxide; Oxcarbazepine; Pharmacodynamic interactions; Protective index; Topiramate

Indexed keywords

7 NITROINDAZOLE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; FELBAMATE; LAMOTRIGINE; NITRIC OXIDE SYNTHASE INHIBITOR; OXCARBAZEPINE; TOPIRAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLINICAL MEDICINE; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CHOICE; DRUG EFFECT; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG TOLERABILITY; ELECTRIC SHOCK; EXPERIMENTAL ANIMAL; LONG TERM MEMORY; LOW DRUG DOSE; MALE; MEMORY DISORDER; MOTOR COORDINATION; MOUSE; NERVE CELL; NEUROLOGIC EXAMINATION; NEUROTOXICITY; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK BENEFIT ANALYSIS; SEIZURE; TASK PERFORMANCE; TREATMENT FAILURE;

ANIMALS; ANTICONVULSANTS; AVOIDANCE LEARNING; DRUG SYNERGISM; ELECTROSHOCK; ENZYME INHIBITORS; INDAZOLES; MALE; MEMORY; MICE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE I; PSYCHOMOTOR PERFORMANCE; SEIZURES;

EID: 33747886423     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-005-0417-y     Document Type: Article

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