Theoretical and structural analysis of the active site of the transcriptional regulators LasR and TraR, using molecular docking methodology for identifying potential analogues of acyl homoserine lactones (AHLs) with anti-quorum sensing activity

European Journal of Medicinal Chemistry

Volumn 45, Issue 2, 2010, Pages 608-615

  Ahumedo, Maicol ^a   Díaz, Antonio ^a   Vivas Reyes, Ricardo ^a  

^a UNIVERSIDAD DE CARTAGENA   (Colombia)

Author keywords

Acyl homoserin lactones; Agrobacterium tumefaciens; Bacteria; Docking; Pseudomonas aeruginosa; Quorum sensing

Indexed keywords

AMIDE; AMINO ACID; BACTERIAL PROTEIN; CARBONYL DERIVATIVE; LASR PROTEIN; LIGAND; N ACYLHOMOSERINE LACTONE; REGULATOR PROTEIN; TRAR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; EXPOSURE; MICROENVIRONMENT; MOLECULAR DOCKING; NONHUMAN; PROTEIN FAMILY; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RHIZOBIUM RADIOBACTER; SEQUENCE HOMOLOGY; STEREOCHEMISTRY; STRUCTURE ANALYSIS; THEORETICAL STUDY; TRANSCRIPTION REGULATION;

ACYL-BUTYROLACTONES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATALYTIC DOMAIN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RHIZOBIUM RADIOBACTER; TRANS-ACTIVATORS;

EID: 73549091234     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.11.004     Document Type: Article

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